Marker check · 5 questions

Family history

Twin studies put lifespan heritability around 20–25%, and having parents or grandparents who lived past 90 meaningfully raises your own odds. You can’t change this marker — it’s here to calibrate the estimate, and because a strong family history of specific diseases should sharpen your screening habits (see Preventive care).

The research

  • Herskind et al., Hum Genet 1996 — lifespan heritability ~25% (Danish twins)
  • van den Berg et al., Nat Commun 2019 — top-10% longest-lived ancestry effect
  • Lloyd-Jones et al., JAMA 2004 — parental premature CVD doubles risk
  1. 1. Did your grandparents / older relatives live long lives?

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  2. 2. Any strong family history of cancer or dementia?

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  3. 3. Any parents or siblings with type 2 diabetes?

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  4. 4. Any close family with a stroke before ~65?

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  5. 5. Any close family with early heart disease (before ~60)?

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