Sources

1 source could not be confirmed against a real DOI/PMID and are marked unresolved below — see each entry’s note.

7 real papers for which PubMed/Crossref couldn’t find a volume, issue, pages, or DOI in this pass — never invented, flagged below with “INCOMPLETE METADATA”.

1. abbasi2012magnesiuminsomnia

   B. Abbasi et al. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res Med Sci, 17(12):1161-9, 2012. Evidence: Low

   Verified 2026-09-22 · PMID 23853635

   n=46; small single trial, not independently replicated at scale.

   • Wiki: Magnesium (supplement)

2. abdelrahman2017cigarettesmoking

   O. Abdel-Rahman et al. Cigarette smoking as a risk factor for the development of and mortality from hepatocellular carcinoma: An updated systematic review of 81 epidemiological studies. J Evid Based Med, 10(4):245-254, 2017. doi:10.1111/jebm.12270 Evidence: High

   Verified 2026-09-26 · PMID 28891275 · DOI 10.1111/jebm.12270

   • What Matters: Habits behind liver cancer death risk

3. abdullah2010overweightobesity

   A. Abdullah et al. The magnitude of association between overweight and obesity and the risk of diabetes: a meta-analysis of prospective cohort studies. Diabetes Res Clin Pract, 89(3):309-19, 2010. doi:10.1016/j.diabres.2010.04.012 Evidence: High

   Verified 2026-09-26 · PMID 20493574 · DOI 10.1016/j.diabres.2010.04.012

   • Wiki: Metabolic health and type 2 diabetes
   • Wiki: Body weight
   • What Matters: What moves diabetes death odds

4. abdullah2011yearslived

   A. Abdullah et al. The number of years lived with obesity and the risk of all-cause and cause-specific mortality. Int J Epidemiol, 40(4):985-96, 2011. doi:10.1093/ije/dyr018 Evidence: Low

   Verified 2026-09-26 · PMID 21357186 · DOI 10.1093/ije/dyr018

   • Wiki: Body weight
   • Deep dive: How much is the extra weight actually costing you?

5. acog2010caffeinepregnancy

   American College of Obstetricians and Gynecologists. ACOG CommitteeOpinion No. 462: Moderate caffeine consumption during pregnancy. Obstet Gynecol, 116(2 Pt 1):467-468, 2010. doi:10.1097/AOG.0b013e3181eeb2a1 Evidence: Not graded (guideline)

   Verified 2026-09-28 · PMID 20664420 · DOI 10.1097/AOG.0b013e3181eeb2a1

   Professional-society committee opinion (guideline); left untiered.

   • Wiki: Coffee, tea and energy drinks
   • Deep dive: The 7 things to know about coffee, tea, and energy drinks

6. afonso2021strengthstretching

   J. Afonso et al. Strength Training versus Stretching for Improving Range of Motion: A Systematic Review and Meta-Analysis. Healthcare (Basel), 9(4):427, 2021. doi:10.3390/healthcare9040427 Evidence: Low

   Verified 2026-09-28 · PMID 33917036 · DOI 10.3390/healthcare9040427

   • Wiki: Flexibility and mobility

7. afshin2014nutlegume

   A. Afshin et al. Consumption of nuts and legumes and risk of incident ischemic heart disease, stroke, and diabetes: a systematic review and meta-analysis. Am J Clin Nutr, 100(1):278-88, 2014. doi:10.3945/ajcn.113.076901 Evidence: High

   Verified 2026-09-26 · PMID 24898241 · DOI 10.3945/ajcn.113.076901

   • What Matters: Habits that swing heart-disease death risk

8. ahn2013incidentchronic

   S. Y. Ahn et al. Incident chronic kidney disease and newly developed complications related to renal dysfunction in an elderly population during 5 years: a community-based elderly population cohort study. PLoS One, 8(12):e84467, 2013. doi:10.1371/journal.pone.0084467 Evidence: Low

   Verified 2026-09-26 · PMID 24367663 · DOI 10.1371/journal.pone.0084467

   • What Matters: Levers on hypertensive disease deaths

9. aimhigh2011niacinadded

   AIM-HIGH Investigators et al. Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy. N Engl J Med, 365(24):2255-67, 2011. doi:10.1056/NEJMoa1107579 Evidence: Moderate

   Verified 2026-09-26 · PMID 22085343 · DOI 10.1056/NEJMoa1107579

   Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

   • Wiki: Cholesterol
   • Deep dive: The 9 things that matter most for your cholesterol

10. akerstedt2019weekendsleep

    T. Åkerstedt et al. Sleep duration and mortality - Does weekend sleep matter?. J Sleep Res, 28(1):e12712, 2019. doi:10.1111/jsr.12712 Evidence: Low

    Verified 2026-09-26 · PMID 29790200 · DOI 10.1111/jsr.12712

    • Wiki: Sleep physiology
    • Wiki: Sleep duration and mortality
    • What Matters: What sleep does to how long you live
    • Deep dive: How sleep affects how long you live
    • What Matters: The healthiest habits, ranked

11. albanese2017midlifebmi

    E. Albanese et al. Body mass index in midlife and dementia: Systematic review and meta-regression analysis of 589,649 men and women followed in longitudinal studies. Alzheimers Dement (Amst), 8(1):165-178, 2017. doi:10.1016/j.dadm.2017.05.007 Evidence: Moderate

    Verified 2026-09-27 · PMID 28761927 · DOI 10.1016/j.dadm.2017.05.007

    • Wiki: Dementia risk factors
    • Deep dive: How to escape dementia: all 14 risk factors, ranked

12. albert2000suddendeath

    C. M. Albert et al. Triggering of sudden death from cardiac causes by vigorous exertion. N Engl J Med, 343(19):1355-61, 2000. doi:10.1056/NEJM200011093431902 Evidence: Low

    Verified 2026-09-28 · PMID 11070099 · DOI 10.1056/NEJM200011093431902

    • Wiki: High-intensity interval training

13. albulescu2022microbreaks

    P. Albulescu et al. "Give me a break!" A systematic review and meta-analysis on the efficacy of micro-breaks for increasing well-being and performance. PLoS One, 17(8):e0272460, 2022. doi:10.1371/journal.pone.0272460 Evidence: Moderate

    Verified 2026-09-26 · PMID 36044424 · DOI 10.1371/journal.pone.0272460

    • What Matters: What stretches, or shreds, attention

14. alimujiang2019lifepurpose

    A. Alimujiang et al. Association Between Life Purpose and Mortality Among US Adults Older Than 50 Years. JAMA Netw Open, 2(5):e194270, 2019. doi:10.1001/jamanetworkopen.2019.4270 Evidence: Low

    Verified 2026-09-27 · PMID 31125099 · DOI 10.1001/jamanetworkopen.2019.4270

    • Wiki: Stress and anxiety
    • Wiki: Social connection
    • Deep dive: The 8 things that matter most for connection and purpose
    • Deep dive: The 8 things that matter most for staying calm

15. alladi2013bilingualismdelays

    S. Alladi et al. Bilingualism delays age at onset of dementia, independent of education and immigration status. Neurology, 81(22):1938-44, 2013. doi:10.1212/01.wnl.0000436620.33155.a4 Evidence: Very low

    Verified 2026-09-26 · PMID 24198291 · DOI 10.1212/01.wnl.0000436620.33155.a4

    • What Matters: What moves your cognitive age
    • Deep dive: How to lower your cognitive age: every habit with a number in years

16. allen2016cogfxindoor

    J. G. Allen et al. Associations of Cognitive Function Scores with Carbon Dioxide, Ventilation, and Volatile Organic Compound Exposures in Office Workers: A Controlled Exposure Study of Green and Conventional Office Environments. Environ Health Perspect, 124(6):805-12, 2016. doi:10.1289/ehp.1510037 Evidence: Low

    Verified 2026-09-26 · PMID 26502459 · DOI 10.1289/ehp.1510037

    Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

    • What Matters: What stretches, or shreds, attention

17. almond2005hyponatremiaamong

    C. S. Almond et al. Hyponatremia among runners in the Boston Marathon. N Engl J Med, 352(15):1550-6, 2005. doi:10.1056/NEJMoa043901 Evidence: Low

    Verified 2026-09-26 · PMID 15829535 · DOI 10.1056/NEJMoa043901

    Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

    • Wiki: Hydration
    • Deep dive: The 7 things worth knowing about hydration

18. altmann2014interruptions

    E. M. Altmann, J. G. Trafton, and D. Z. Hambrick. Momentary interruptions can derail the train of thought. J Exp Psychol Gen, 143(1):215-26, 2014. doi:10.1037/a0030986 Evidence: Very low

    Verified 2026-09-28 · PMID 23294345 · DOI 10.1037/a0030986

    • What Matters: What stretches, or shreds, attention

19. alvarezbueno2019lowversus

    C. Álvarez-Bueno et al. Comparative Effect of Low-Glycemic Index versus High-Glycemic Index Breakfasts on Cognitive Function: A Systematic Review and Meta-Analysis. Nutrients, 11(8):1706, 2019. doi:10.3390/nu11081706 Evidence: Moderate

    Verified 2026-09-26 · PMID 31344892 · DOI 10.3390/nu11081706

    Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

    • What Matters: What stretches, or shreds, attention

20. american2023healthysleep

    American College of Cardiology. Getting Good Sleep Could Add Years to Your Life. American College of Cardiology, 2023. Evidence: Not graded (news release)

    Verified 2026-09-27

    Original URL was dead (404); replaced with the correct current URL for the same page, confirmed live.

    • Wiki: Sleep duration and mortality
    • Deep dive: The 8 things that matter most for your sleep

21. americannacolorectalcancer

    American Cancer Society. American Cancer Society Guideline for Colorectal Cancer Screening. American Cancer Society. Evidence: Not graded (guideline)

    Verified 2026-09-27

    Continuously-updated agency resource page, no single publication year stated.

    • Wiki: Family history and genetics
    • Deep dive: What you inherit from your family, and what you don’t

22. americannahairloss

    American Academy of Dermatology. Hair Loss Resource Center. American Academy of Dermatology. Evidence: Not graded (reference page)

    Verified 2026-09-27

    Continuously-updated patient resource page, no single publication year stated.

    • Wiki: Hair loss
    • Deep dive: The 9 things balding is actually telling you about your health

23. americannahayfever

    American College of Allergy, Asthma and Immunology. Hay Fever (Rhinitis). ACAAI. Evidence: Not graded (reference page)

    Verified 2026-09-27

    • Wiki: Skin aging
    • Deep dive: What your eyebags are actually telling you about your health

24. americannahypothyroidism

    American Thyroid Association. Hypothyroidism. American Thyroid Association. Evidence: Not graded (reference page)

    Verified 2026-09-27

    • Wiki: Skin aging
    • Deep dive: What your eyebags are actually telling you about your health

25. anagnostakis2025radiomicproteomic

    F. Anagnostakis et al. Radiomic and proteomic signatures of body mass index on brain ageing and Alzheimer's-like patterns of brain atrophy. EBioMedicine, 116:105763, 2025. doi:10.1016/j.ebiom.2025.105763 Evidence: Very low

    Verified 2026-09-26 · PMID 40435724 · DOI 10.1016/j.ebiom.2025.105763

    • What Matters: What moves your cognitive age
    • Deep dive: How to lower your cognitive age: every habit with a number in years

26. anda1999adversechildhood

    R. F. Anda et al. Adverse childhood experiences and smoking during adolescence and adulthood. JAMA, 282(17):1652-8, 1999. doi:10.1001/jama.282.17.1652 Evidence: Very low

    Verified 2026-09-26 · PMID 10553792 · DOI 10.1001/jama.282.17.1652

    • Wiki: Adverse childhood experiences
    • Deep dive: Adverse childhood experiences: what an ACE score predicts, and what still helps now

27. anda2020insideadverse

    R. F. Anda, L. E. Porter, and D. W. Brown. Inside the Adverse Childhood Experience Score: Strengths, Limitations, and Misapplications. Am J Prev Med, 59(2):293-295, 2020. doi:10.1016/j.amepre.2020.01.009 Evidence: Not graded (review)

    Verified 2026-09-26 · PMID 32222260 · DOI 10.1016/j.amepre.2020.01.009

    • Wiki: Adverse childhood experiences
    • Deep dive: Adverse childhood experiences: what an ACE score predicts, and what still helps now

28. andreasson2017waisthip

    A. Andreasson et al. Waist/Hip Ratio Better Predicts Development of Severe Liver Disease Within 20 Years Than Body Mass Index: A Population-based Cohort Study. Clin Gastroenterol Hepatol, 15(8):1294-1301.e2, 2017. doi:10.1016/j.cgh.2017.02.040 Evidence: Low

    Verified 2026-09-26 · PMID 28342948 · DOI 10.1016/j.cgh.2017.02.040

    • What Matters: Factors that swing liver disease deaths

29. anglemyer2014firearmaccess

    A. Anglemyer, T. Horvath, and G. Rutherford. The accessibility of firearms and risk for suicide and homicide victimization among household members: a systematic review and meta-analysis. Ann Intern Med, 160(2):101-10, 2014. doi:10.7326/M13-1301 Evidence: Moderate

    Verified 2026-09-26 · PMID 24592495 · DOI 10.7326/M13-1301

    Metadata confirmed against the Europe PMC MEDLINE record for this PMID (NCBI E-utilities unavailable 2026-09-26). The abstract carries a published correction: 16 studies, suicide OR 3.24.

    • What Matters: Factors linked to suicide deaths

30. ansari2024primarysjogren

    N. Ansari and M. Salesi. The association between primary Sjogren's syndrome and non-Hodgkin's lymphoma: a systematic review and meta-analysis of cohort studies. Clin Rheumatol, 43(7):2177-2186, 2024. doi:10.1007/s10067-024-06993-6 Evidence: High

    Verified 2026-09-26 · PMID 38722505 · DOI 10.1007/s10067-024-06993-6

    • What Matters: What moves blood-cancer death risk

31. appel1997dashdiet

    L. J. Appel et al. A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group. N Engl J Med, 336(16):1117-24, 1997. doi:10.1056/NEJM199704173361601 Evidence: Low

    Verified 2026-09-26 · PMID 9099655 · DOI 10.1056/NEJM199704173361601

    Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

    • Wiki: Blood pressure
    • Deep dive: Is your blood pressure quietly aging you? The 9 things that matter most

32. appleby2016mortalityvegetarians

    P. N. Appleby et al. Mortality in vegetarians and comparable nonvegetarians in the United Kingdom. Am J Clin Nutr, 103(1):218-30, 2016. doi:10.3945/ajcn.115.119461 Evidence: Moderate

    Verified 2026-09-26 · PMID 26657045 · DOI 10.3945/ajcn.115.119461

    • Wiki: Dietary patterns
    • Deep dive: Vegan, vegetarian, omnivore, carnivore: what the labels actually buy you

33. araujo202210second

    C. G. Araujo et al. Successful 10-second one-legged stance performance predicts survival in middle-aged and older individuals. Br J Sports Med, 56(17):975-980, 2022. doi:10.1136/bjsports-2021-105360 Evidence: Low

    Verified 2026-09-26 · PMID 35728834 · DOI 10.1136/bjsports-2021-105360

    Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

    • Wiki: Balance training
    • Wiki: Functional fitness
    • Wiki: Balance, mobility and function (section)
    • What Matters: Movement: What Matters?
    • Deep dive: Body Check: five at-home tests linked to how long you live

34. araujo2024bodyflexibility

    C. G. S. Araújo et al. Reduced Body Flexibility Is Associated With Poor Survival in Middle-Aged Men and Women: A Prospective Cohort Study. Scand J Med Sci Sports, 34(8):e14708, 2024. doi:10.1111/sms.14708 Evidence: Low

    Verified 2026-09-26 · PMID 39165228 · DOI 10.1111/sms.14708

    Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

    • Wiki: Flexibility and mobility
    • Wiki: Balance, mobility and function (section)
    • What Matters: Movement: What Matters?

35. arcelus2011mortalityeating

    J. Arcelus et al. Mortality rates in patients with anorexia nervosa and other eating disorders. A meta-analysis of 36 studies. Arch Gen Psychiatry, 68(7):724-31, 2011. doi:10.1001/archgenpsychiatry.2011.74 Evidence: High

    Verified 2026-09-26 · PMID 21727255 · DOI 10.1001/archgenpsychiatry.2011.74

    • Wiki: Mental health conditions and lifespan
    • Deep dive: The mental health conditions that cost the most years, ranked

36. arem2015leisuretime

    H. Arem et al. Leisure time physical activity and mortality: a detailed pooled analysis of the dose-response relationship. JAMA Intern Med, 175(6):959-67, 2015. doi:10.1001/jamainternmed.2015.0533 Evidence: High

    Verified 2026-09-27 · PMID 25844730 · DOI 10.1001/jamainternmed.2015.0533

    • Wiki: Exercise and longevity
    • Wiki: Zone 2 training
    • Wiki: Exercise (section)
    • Wiki: Cardio and aerobic fitness (section)
    • What Matters: Movement: What Matters?
    • Deep dive: The 8 things that matter most in exercise
    • Quiz: Exercise

37. armstrong2012milddehydration

    L. E. Armstrong et al. Mild dehydration affects mood in healthy young women. J Nutr, 142(2):382-8, 2012. doi:10.3945/jn.111.142000 Evidence: Low

    Verified 2026-09-26 · PMID 22190027 · DOI 10.3945/jn.111.142000

    • Wiki: Hydration
    • Deep dive: The 7 things worth knowing about hydration

38. asfour2023maleandrogenetic

    L. Asfour, W. Cranwell, and R. Sinclair. Male Androgenetic Alopecia. Endotext [Internet], MDText.com, 2023. Evidence: Not graded (reference page)

    Verified 2026-09-29 · PMID 25905192

    Endotext online textbook chapter (updated 2023 Jan 25), indexed in PubMed with abstract; narrative review, left untiered.

    • Wiki: Hair loss
    • Wiki: Skin and hair (section)

39. asher2022periodontalhealth

    S. Asher et al. Periodontal health, cognitive decline, and dementia: A systematic review and meta-analysis of longitudinal studies. J Am Geriatr Soc, 70(9):2695-2709, 2022. doi:10.1111/jgs.17978 Evidence: Low

    Verified 2026-09-26 · PMID 36073186 · DOI 10.1111/jgs.17978

    • Wiki: Oral health
    • Wiki: Digestive and oral health (section)
    • What Matters: What raises dementia risk most
    • Deep dive: How to escape dementia: all 14 risk factors, ranked
    • Deep dive: Does oral care actually affect how long you live?
    • What Matters: Factors behind Alzheimer’s death risk

40. ashwell2012whtr

    M. Ashwell, P. Gunn, and S. Gibson. Waist-to-height ratio is a better screening tool than waist circumference and BMI for adult cardiometabolic risk factors: systematic review and meta-analysis. Obes Rev, 13(3):275-286, 2012. doi:10.1111/j.1467-789X.2011.00952.x Evidence: Very low

    Verified 2026-09-30 · PMID 22106927 · DOI 10.1111/j.1467-789X.2011.00952.x

    • Deep dive: Body Check: five at-home tests linked to how long you live

41. athey2025substancesuicide

    A. Athey et al. Association of substance use with suicide mortality: An updated systematic review and meta-analysis. Drug Alcohol Depend Rep, 14:100310, 2025. doi:10.1016/j.dadr.2024.100310 Evidence: Moderate

    Verified 2026-09-26 · PMID 39830682 · DOI 10.1016/j.dadr.2024.100310

    Metadata confirmed against the Europe PMC MEDLINE record for this PMID (NCBI E-utilities unavailable 2026-09-26). Online-only journal: article number, no issue. The abstract’s alcohol SMR (65.39, CI 3.02–19.62) is internally inconsistent and is not used.

    • What Matters: Factors linked to suicide deaths

42. aune2011dietaryfibre

    D. Aune et al. Dietary fibre, whole grains, and risk of colorectal cancer: systematic review and dose-response meta-analysis of prospective studies. BMJ, 343:d6617, 2011. doi:10.1136/bmj.d6617 Evidence: High

    Verified 2026-09-26 · PMID 22074852 · DOI 10.1136/bmj.d6617

    • What Matters: What changes bowel cancer death risk

43. aune2012bodymass

    D. Aune et al. Body mass index, abdominal fatness and pancreatic cancer risk: a systematic review and non-linear dose-response meta-analysis of prospective studies. Ann Oncol, 23(4):843-52, 2012. doi:10.1093/annonc/mdr398 Evidence: High

    Verified 2026-09-26 · PMID 21890910 · DOI 10.1093/annonc/mdr398

    • What Matters: What moves pancreatic cancer death risk

44. aune2013wholegrain

    D. Aune et al. Whole grain and refined grain consumption and the risk of type 2 diabetes: a systematic review and dose-response meta-analysis of cohort studies. Eur J Epidemiol, 28(11):845-58, 2013. doi:10.1007/s10654-013-9852-5 Evidence: Moderate

    Verified 2026-09-26 · PMID 24158434 · DOI 10.1007/s10654-013-9852-5

    • What Matters: What moves diabetes death odds

45. aune2015anthropometricfactors

    D. Aune et al. Anthropometric factors and endometrial cancer risk: a systematic review and dose-response meta-analysis of prospective studies. Ann Oncol, 26(8):1635-48, 2015. doi:10.1093/annonc/mdv142 Evidence: High

    Verified 2026-09-26 · PMID 25791635 · DOI 10.1093/annonc/mdv142

    • What Matters: Habits that change uterine cancer death risk

46. aune2016nuts

    D. Aune et al. Nut consumption and risk of cardiovascular disease, total cancer, all-cause and cause-specific mortality: a systematic review and dose-response meta-analysis of prospective studies. BMC Med, 14(1):207, 2016. doi:10.1186/s12916-016-0730-3 Evidence: High

    Verified 2026-10-01 · PMID 27916000 · DOI 10.1186/s12916-016-0730-3

    • Wiki: Nuts
    • Wiki: Foods (section)
    • What Matters: Foods ranked for longevity

47. aune2016wholegrain

    D. Aune et al. Whole grain consumption and risk of cardiovascular disease, cancer, and all cause and cause specific mortality: systematic review and dose-response meta-analysis of prospective studies. BMJ, 353:i2716, 2016. doi:10.1136/bmj.i2716 Evidence: High

    Verified 2026-09-27 · PMID 27301975 · DOI 10.1136/bmj.i2716

    • Wiki: Dietary fiber
    • Wiki: Whole grains
    • Deep dive: Why doctors will not shut up about fiber

48. aune2017fruitvegetable

    D. Aune et al. Fruit and vegetable intake and the risk of cardiovascular disease, total cancer and all-cause mortality-a systematic review and dose-response meta-analysis of prospective studies. Int J Epidemiol, 46(3):1029-1056, 2017. doi:10.1093/ije/dyw319 Evidence: High

    Verified 2026-09-26 · PMID 28338764 · DOI 10.1093/ije/dyw319

    • Wiki: Leafy greens
    • Wiki: Vegetables
    • Wiki: Citrus fruit
    • What Matters: Habits that change cancer death risk

49. aune2017restingheart

    D. Aune et al. Resting heart rate and the risk of cardiovascular disease, total cancer, and all-cause mortality - A systematic review and dose-response meta-analysis of prospective studies. Nutr Metab Cardiovasc Dis, 27(6):504-517, 2017. doi:10.1016/j.numecd.2017.04.004 Evidence: Moderate

    Verified 2026-09-26 · PMID 28552551 · DOI 10.1016/j.numecd.2017.04.004

    • Wiki: Cardiovascular disease
    • Deep dive: The 10 things that matter most for your heart

50. axelsson2010beautysleep

    J. Axelsson et al. Beauty sleep: experimental study on the perceived health and attractiveness of sleep deprived people. BMJ, 341:c6614, 2010. doi:10.1136/bmj.c6614 Evidence: Very low

    Verified 2026-09-27 · PMID 21156746 · DOI 10.1136/bmj.c6614

    Automated link-check got HTTP 429 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

    • Wiki: Skin aging
    • Deep dive: What your eyebags are actually telling you about your health

51. ayoubcharette2025lncs

    S. Ayoub-Charette et al. Reconciling conflicting evidence on low- and no-calorie sweeteners and cardiometabolic outcomes: an umbrella review using naïve and bias-adjusted methods. Appl Physiol Nutr Metab, 50:1-26, 2025. doi:10.1139/apnm-2025-0068 Evidence: Low

    Verified 2026-10-01 · PMID 41428417 · DOI 10.1139/apnm-2025-0068

    • Wiki: Diet drinks
    • Deep dive: Diet soda vs regular soda vs water: what the evidence shows

52. ba2021mushroommeta

    D. M. Ba et al. Prospective study of dietary mushroom intake and risk of mortality: results from continuous National Health and Nutrition Examination Survey (NHANES) 2003-2014 and a meta-analysis. Nutr J, 20(1):80, 2021. doi:10.1186/s12937-021-00738-w Evidence: Moderate

    Verified 2026-10-01 · PMID 34548082 · DOI 10.1186/s12937-021-00738-w

    • Wiki: Mushrooms
    • What Matters: Foods ranked for longevity

53. ba2021mushroomnhanes3

    D. M. Ba et al. Association of mushroom consumption with all-cause and cause-specific mortality among American adults: prospective cohort study findings from NHANES III. Nutr J, 20(1):38, 2021. doi:10.1186/s12937-021-00691-8 Evidence: Low

    Verified 2026-10-01 · PMID 33888143 · DOI 10.1186/s12937-021-00691-8

    • Wiki: Mushrooms

54. bach2019healthydietary

    K. E. Bach et al. Healthy Dietary Patterns and Incidence of CKD: A Meta-Analysis of Cohort Studies. Clin J Am Soc Nephrol, 14(10):1441-1449, 2019. doi:10.2215/CJN.00530119 Evidence: Moderate

    Verified 2026-09-26 · PMID 31551237 · DOI 10.2215/CJN.00530119

    • What Matters: Factors that swing kidney disease deaths

55. bagnardi2015alcoholconsumption

    V. Bagnardi et al. Alcohol consumption and site-specific cancer risk: a comprehensive dose-response meta-analysis. Br J Cancer, 112(3):580-93, 2015. doi:10.1038/bjc.2014.579 Evidence: High

    Verified 2026-09-26 · PMID 25422909 · DOI 10.1038/bjc.2014.579

    • Wiki: Alcohol
    • What Matters: Habits that change cancer death risk
    • What Matters: What changes bowel cancer death risk
    • What Matters: Habits behind liver cancer death risk

56. baker2011senescentclearance

    D. J. Baker et al. Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature, 479(7372):232-6, 2011. doi:10.1038/nature10600 Evidence: Very low

    Verified 2026-09-28 · PMID 22048312 · DOI 10.1038/nature10600

    • Wiki: Telomeres
    • Wiki: Inflammation and aging

57. baker2023effectscocoa

    L. D. Baker et al. Effects of cocoa extract and a multivitamin on cognitive function: A randomized clinical trial. Alzheimers Dement, 19(4):1308-1319, 2023. doi:10.1002/alz.12767 Evidence: Moderate

    Verified 2026-09-26 · PMID 36102337 · DOI 10.1002/alz.12767

    • Deep dive: How to lower your cognitive age: every habit with a number in years

58. balban2023cyclicsighing

    M. Y. Balban et al. Brief structured respiration practices enhance mood and reduce physiological arousal. Cell Rep Med, 4(1):100895, 2023. doi:10.1016/j.xcrm.2022.100895 Evidence: Low

    Verified 2026-10-08 · PMID 36630953 · DOI 10.1016/j.xcrm.2022.100895

    • Deep dive: Top 10 insomnia remedies, ranked by the evidence

59. bamberg2025acutefasting

    C. Bamberg and D. Moreau. Acute effects of fasting on cognitive performance: A systematic review and meta-analysis. Psychol Bull, 151(9):1147-1169, 2025. doi:10.1037/bul0000492 Evidence: High

    Verified 2026-09-26 · PMID 41182703 · DOI 10.1037/bul0000492

    • What Matters: What stretches, or shreds, attention

60. bandera2007fruitsvegetables

    E. V. Bandera et al. Fruits and vegetables and endometrial cancer risk: a systematic literature review and meta-analysis. Nutr Cancer, 58(1):6-21, 2007. doi:10.1080/01635580701307929 Evidence: Low

    Verified 2026-09-26 · PMID 17571962 · DOI 10.1080/01635580701307929

    • What Matters: Habits that change uterine cancer death risk

61. baniassadi2023nighttimeambient

    A. Baniassadi et al. Nighttime ambient temperature and sleep in community-dwelling older adults. Sci Total Environ, 899:165623, 2023. doi:10.1016/j.scitotenv.2023.165623 Evidence: Low

    Verified 2026-09-26 · PMID 37474050 · DOI 10.1016/j.scitotenv.2023.165623

    • Wiki: Sleep physiology
    • Wiki: Insomnia
    • Wiki: Sleep quality
    • What Matters: What actually moves sleep quality
    • Deep dive: What matters most for high-quality sleep
    • Deep dive: Bryan Johnson's Ten Sleep Power Laws: what each one asks and how strong the evidence is
    • Deep dive: Top 10 insomnia remedies, ranked by the evidence
    • What Matters: The healthiest habits, ranked

62. bannai2012glycinemedicine

    M. Bannai and N. Kawai. New therapeutic strategy for amino acid medicine: glycine improves the quality of sleep. J Pharmacol Sci, 118(2):145-8, 2012. doi:10.1254/jphs.11r04fm Evidence: Very low

    Verified 2026-09-22 · PMID 22293292 · DOI 10.1254/jphs.11r04fm

    PR #555 audit: the original PMID (22673476) resolved to an unrelated dental fluvastatin-gel study; corrected to 22293292.

    • Wiki: Glycine (supplement)

63. bansal2013type2

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    Verified 2026-09-26 · PMID 23032360 · DOI 10.1038/pcan.2012.40

    • What Matters: Levers on prostate cancer death risk

64. bao2013nutconsumption

    Y. Bao et al. Association of nut consumption with total and cause-specific mortality. N Engl J Med, 369(21):2001-11, 2013. doi:10.1056/NEJMoa1307352 Evidence: Moderate

    Verified 2026-09-26 · PMID 24256379 · DOI 10.1056/NEJMoa1307352

    Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

    • Wiki: Dietary patterns
    • Deep dive: The 8 things that matter most on your plate

65. bao2013pancreaticcancer

    Y. Bao et al. Nut consumption and risk of pancreatic cancer in women. Br J Cancer, 109(11):2911-6, 2013. doi:10.1038/bjc.2013.665 Evidence: Low

    Verified 2026-09-26 · PMID 24149179 · DOI 10.1038/bjc.2013.665

    • What Matters: What moves pancreatic cancer death risk

66. barnes2023minddiet

    L. L. Barnes et al. Trial of the MIND Diet for Prevention of Cognitive Decline in Older Persons. N Engl J Med, 389(7):602-611, 2023. doi:10.1056/NEJMoa2302368 Evidence: Moderate

    Verified 2026-09-26 · PMID 37466280 · DOI 10.1056/NEJMoa2302368

    • Wiki: Dementia risk factors
    • Deep dive: Plants and your brain: what the vegetarian, Mediterranean and MIND studies really show about dementia

67. barry2014fitnessvs

    V. W. Barry et al. Fitness vs. fatness on all-cause mortality: a meta-analysis. Prog Cardiovasc Dis, 56(4):382-90, 2014. doi:10.1016/j.pcad.2013.09.002 Evidence: High

    Verified 2026-09-26 · PMID 24438729 · DOI 10.1016/j.pcad.2013.09.002

    • Wiki: VO2 max
    • Wiki: Body weight
    • Deep dive: How much is the extra weight actually costing you?
    • Quiz: Weight check

68. baskaran2019smokingpneumonia

    V. Baskaran et al. Effect of tobacco smoking on the risk of developing community acquired pneumonia: A systematic review and meta-analysis. PLoS One, 14(7):e0220204, 2019. doi:10.1371/journal.pone.0220204 Evidence: High

    Verified 2026-09-26 · PMID 31318967 · DOI 10.1371/journal.pone.0220204

    • What Matters: Factors that swing flu and pneumonia deaths

69. basner2018whoenvironmental

    M. Basner and S. McGuire. WHO Environmental Noise Guidelines for the European Region: A Systematic Review on Environmental Noise and Effects on Sleep. Int J Environ Res Public Health, 15(3):519, 2018. doi:10.3390/ijerph15030519 Evidence: Moderate

    Verified 2026-09-26 · PMID 29538344 · DOI 10.3390/ijerph15030519

    Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

    • Deep dive: What matters most for high-quality sleep

70. bastien2001insomniaseverity

    C. H. Bastien, A. Vallières, and C. M. Morin. Validation of the Insomnia Severity Index as an outcome measure for insomnia research. Sleep Med, 2(4):297-307, 2001. doi:10.1016/s1389-9457(00)00065-4 Evidence: Not graded (measurement tool)

    Verified 2026-09-28 · PMID 11438246 · DOI 10.1016/s1389-9457(00)00065-4

    Instrument-validation paper cited for ISI score bands; not an outcome claim, left untiered.

    • Wiki: Insomnia
    • What Matters: What actually moves sleep quality

71. bateman2012biomarkertimeline

    R. J. Bateman et al. Clinical and biomarker changes in dominantly inherited Alzheimer's disease. N Engl J Med, 367(9):795-804, 2012. doi:10.1056/NEJMoa1202753 Evidence: Very low

    Verified 2026-09-26 · PMID 22784036 · DOI 10.1056/NEJMoa1202753

    Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

    • Wiki: Dementia risk factors
    • Deep dive: The 8 things to know about Alzheimer’s risk

72. bauer2013protage

    J. Bauer et al. Evidence-based recommendations for optimal dietary protein intake in older people: a position paper from the PROT-AGE Study Group. J Am Med Dir Assoc, 14(8):542-59, 2013. doi:10.1016/j.jamda.2013.05.021 Evidence: Not graded (guideline)

    Verified 2026-09-28 · PMID 23867520 · DOI 10.1016/j.jamda.2013.05.021

    Expert position paper (PROT-AGE Study Group recommendations); left untiered.

    • Wiki: Muscle mass
    • Wiki: Sarcopenia
    • Quiz: Diet check

73. bavishi2016bookreading

    A. Bavishi, M. D. Slade, and B. R. Levy. A chapter a day: Association of book reading with longevity. Soc Sci Med, 164:44-48, 2016. doi:10.1016/j.socscimed.2016.07.014 Evidence: Low

    Verified 2026-09-28 · PMID 27471129 · DOI 10.1016/j.socscimed.2016.07.014

    • What Matters: What moves your cognitive age
    • What Matters: The healthiest habits, ranked

74. beaudart2017sarcopeniaoutcomes

    C. Beaudart et al. Health Outcomes of Sarcopenia: A Systematic Review and Meta-Analysis. PLoS One, 12(1):e0169548, 2017. doi:10.1371/journal.pone.0169548 Evidence: Moderate

    Verified 2026-09-28 · PMID 28095426 · DOI 10.1371/journal.pone.0169548

    • Wiki: Sarcopenia

75. bediou2018actionvideo

    B. Bediou et al. Meta-analysis of action video game impact on perceptual, attentional, and cognitive skills. Psychol Bull, 144(1):77-110, 2018. doi:10.1037/bul0000130 Evidence: Moderate

    Verified 2026-09-26 · PMID 29172564 · DOI 10.1037/bul0000130

    • What Matters: What stretches, or shreds, attention

76. behm2016stretching

    D. G. Behm et al. Acute effects of muscle stretching on physical performance, range of motion, and injury incidence in healthy active individuals: a systematic review. Appl Physiol Nutr Metab, 41(1):1-11, 2016. doi:10.1139/apnm-2015-0235 Evidence: Moderate

    Verified 2026-09-28 · PMID 26642915 · DOI 10.1139/apnm-2015-0235

    • Wiki: Flexibility and mobility

77. behrens2014bodysize

    G. Behrens et al. Body size and physical activity in relation to incidence of chronic obstructive pulmonary disease. CMAJ, 186(12):E457-69, 2014. doi:10.1503/cmaj.140025 Evidence: Low

    Verified 2026-09-26 · PMID 25002559 · DOI 10.1503/cmaj.140025

    • What Matters: Factors that swing COPD deaths

78. benjafield2019osaprevalence

    A. V. Benjafield et al. Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis. Lancet Respir Med, 7(8):687-698, 2019. doi:10.1016/S2213-2600(19)30198-5 Evidence: Very low

    Verified 2026-09-28 · PMID 31300334 · DOI 10.1016/S2213-2600(19)30198-5

    • Wiki: Insomnia
    • Wiki: Sleep duration and mortality
    • Wiki: Sleep quality
    • Wiki: Sleep (section)
    • Deep dive: Top 10 insomnia remedies, ranked by the evidence

79. benke2009valerenicacid

    D. Benke et al. GABA A receptors as in vivo substrate for the anxiolytic action of valerenic acid, a major constituent of valerian root extracts. Neuropharmacology, 56(1):174-181, 2009. doi:10.1016/j.neuropharm.2008.06.013 Evidence: Very low

    Verified 2026-09-28 · PMID 18602406 · DOI 10.1016/j.neuropharm.2008.06.013

    • Wiki: Valerian (supplement)

80. bent2006valerian

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    PR #555 audit: the original PMID (17085453, also cited with the wrong year) resolved to an unrelated hTERT mRNA-stabilization paper; corrected to 17145239. A meta-analysis, but the pooled effect is small and individual trials are inconsistent — kept at "moderate" rather than "high" for that reason.

    • Wiki: Supplements (section)
    • Wiki: Valerian (supplement)
    • Deep dive: Top 10 insomnia remedies, ranked by the evidence

81. berwick1996screeningcutaneous

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    Verified 2026-09-26 · PMID 8847720 · DOI 10.1093/jnci/88.1.17

    • What Matters: Sun and the rest: melanoma death risk

82. best2018noninvasivediagnostic

    L. M. Best et al. Non-invasive diagnostic tests for Helicobacter pylori infection. Cochrane Database Syst Rev, 3(3):CD012080, 2018. doi:10.1002/14651858.CD012080.pub2 Evidence: Moderate

    Verified 2026-10-04 · PMID 29543326 · DOI 10.1002/14651858.CD012080.pub2

    • Wiki: Helicobacter pylori
    • Deep dive: H. pylori and stomach cancer: what the evidence shows

83. bethell2019positivechildhood

    C. Bethell et al. Positive Childhood Experiences and Adult Mental and Relational Health in a Statewide Sample: Associations Across Adverse Childhood Experiences Levels. JAMA Pediatr, 173(11):e193007, 2019. doi:10.1001/jamapediatrics.2019.3007 Evidence: Very low

    Verified 2026-09-26 · PMID 31498386 · DOI 10.1001/jamapediatrics.2019.3007

    • Wiki: Adverse childhood experiences
    • Deep dive: Adverse childhood experiences: what an ACE score predicts, and what still helps now

84. beukers2021lowernumber

    N. G. F. M. Beukers et al. Lower Number of Teeth Is Related to Higher Risks for ACVD and Death-Systematic Review and Meta-Analyses of Survival Data. Front Cardiovasc Med, 8:621626, 2021. doi:10.3389/fcvm.2021.621626 Evidence: High

    Verified 2026-09-26 · PMID 34026863 · DOI 10.3389/fcvm.2021.621626

    • Wiki: Oral health
    • Deep dive: Does oral care actually affect how long you live?

85. bhaskaran2018bmiall

    K. Bhaskaran et al. Association of BMI with overall and cause-specific mortality: a population-based cohort study of 3·6 million adults in the UK. Lancet Diabetes Endocrinol, 6(12):944-953, 2018. doi:10.1016/S2213-8587(18)30288-2 Evidence: Low

    Verified 2026-09-26 · PMID 30389323 · DOI 10.1016/S2213-8587(18)30288-2

    • Wiki: Body weight
    • Deep dive: How much is the extra weight actually costing you?

86. bialystok2007bilingualismas

    E. Bialystok, F. I. Craik, and M. Freedman. Bilingualism as a protection against the onset of symptoms of dementia. Neuropsychologia, 45(2):459-64, 2007. doi:10.1016/j.neuropsychologia.2006.10.009 Evidence: Very low

    Verified 2026-09-26 · PMID 17125807 · DOI 10.1016/j.neuropsychologia.2006.10.009

    • Wiki: Cognitive aging
    • What Matters: What moves your cognitive age
    • Deep dive: How to lower your cognitive age: every habit with a number in years

87. biswas2015sedentarytime

    A. Biswas et al. Sedentary time and its association with risk for disease incidence, mortality, and hospitalization in adults: a systematic review and meta-analysis. Ann Intern Med, 162(2):123-32, 2015. doi:10.7326/M14-1651 Evidence: Moderate

    Verified 2026-09-26 · PMID 25599350 · DOI 10.7326/M14-1651

    • Wiki: Sedentary time
    • What Matters: Habits that swing heart-disease death risk

88. black2015mindfulnesspsqi

    D. S. Black et al. Mindfulness meditation and improvement in sleep quality and daytime impairment among older adults with sleep disturbances: a randomized clinical trial. JAMA Intern Med, 175(4):494-501, 2015. doi:10.1001/jamainternmed.2014.8081 Evidence: Low

    Verified 2026-09-26 · PMID 25686304 · DOI 10.1001/jamainternmed.2014.8081

    • Wiki: Sleep quality
    • What Matters: What actually moves sleep quality
    • Deep dive: What matters most for high-quality sleep
    • What Matters: The healthiest habits, ranked

89. blumenthal2016stressmanagement

    J. A. Blumenthal et al. Enhancing Cardiac Rehabilitation With Stress Management Training: A Randomized, Clinical Efficacy Trial. Circulation, 133(14):1341-50, 2016. doi:10.1161/CIRCULATIONAHA.115.018926 Evidence: Low

    Verified 2026-09-26 · PMID 27045127 · DOI 10.1161/CIRCULATIONAHA.115.018926

    • Wiki: Stress and anxiety
    • Deep dive: The 8 things that matter most for staying calm

90. bodnar1998telomerase

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    • Wiki: Telomeres

91. bolland2018vitamindmusculoskeletal

    M. J. Bolland, A. Grey, and A. Avenell. Effects of vitamin D supplementation on musculoskeletal health: a systematic review, meta-analysis, and trial sequential analysis. Lancet Diabetes Endocrinol, 6(11):847-858, 2018. doi:10.1016/S2213-8587(18)30265-1 Evidence: High

    Verified 2026-09-28 · PMID 30293909 · DOI 10.1016/S2213-8587(18)30265-1

    • Wiki: Fall prevention

92. bondonno2023flavonoidfoods

    N. P. Bondonno et al. Change in habitual intakes of flavonoid-rich foods and mortality in US males and females. BMC Med, 21(1):181, 2023. doi:10.1186/s12916-023-02873-z Evidence: Low

    Verified 2026-10-01 · PMID 37173745 · DOI 10.1186/s12916-023-02873-z

    • Wiki: Berries
    • Wiki: Citrus fruit

93. boniol2012indoortanning

    M. Boniol et al. Cutaneous melanoma attributable to sunbed use: systematic review and meta-analysis. BMJ, 345:e4757, 2012. doi:10.1136/bmj.e4757 Evidence: High

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    • Wiki: Skin aging
    • Deep dive: What your skin is actually telling you about how long you live
    • What Matters: Sun and the rest: melanoma death risk

94. boonstra2015gaba

    E. Boonstra et al. Neurotransmitters as food supplements: the effects of GABA on brain and behavior. Front Psychol, 6:1520, 2015. doi:10.3389/fpsyg.2015.01520 Evidence: Very low

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    Front Psychol is a continuous-publication journal with no issue number.

    • Wiki: Supplements (section)
    • Wiki: GABA (supplement)

95. bootzin1972stimuluscontrolINCOMPLETE METADATA

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    PR #555 audit: the original psycnet.apa.org record could not be confirmed (JS-only page); replaced with a verified PDF of the actual paper hosted by Penn CBTI. The DOI is the APA PsycEXTRA record of the same paper (Crossref dates it 1973).

    • Wiki: Insomnia
    • Deep dive: Bryan Johnson's Ten Sleep Power Laws: what each one asks and how strong the evidence is
    • Deep dive: Top 10 insomnia remedies, ranked by the evidence

96. borbely1982twoprocess

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    • Wiki: Sleep physiology
    • Wiki: Sleep (section)

97. bosettinapanc4ann

    C. Bosetti et al. Cigarette smoking and pancreatic cancer: an analysis from the International Pancreatic Cancer Case-Control Consortium (Panc4). Ann Oncol, 23(7):1880-8, 2012. doi:10.1093/annonc/mdr541 Evidence: Moderate

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    • What Matters: What moves pancreatic cancer death risk

98. botteri2008smokingcolorectal

    E. Botteri et al. Smoking and colorectal cancer: a meta-analysis. JAMA, 300(23):2765-78, 2008. doi:10.1001/jama.2008.839 Evidence: High

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    • Wiki: Colon health
    • Deep dive: The 9 things that matter most for your colon
    • What Matters: What changes bowel cancer death risk

99. boubekri2014daylightwindows

    M. Boubekri et al. Impact of windows and daylight exposure on overall health and sleep quality of office workers: a case-control pilot study. J Clin Sleep Med, 10(6):603-11, 2014. doi:10.5664/jcsm.3780 Evidence: Very low

    Verified 2026-09-26 · PMID 24932139 · DOI 10.5664/jcsm.3780

    • What Matters: What actually moves sleep quality
    • Deep dive: What matters most for high-quality sleep
    • What Matters: The healthiest habits, ranked

100. bouchard1998vo2maxheritability

     C. Bouchard et al. Familial resemblance for VO2max in the sedentary state: the HERITAGE family study. Med Sci Sports Exerc, 30(2):252-8, 1998. doi:10.1097/00005768-199802000-00013 Evidence: Very low

     Verified 2026-09-28 · PMID 9502354 · DOI 10.1097/00005768-199802000-00013

     • Wiki: VO2 max

101. bouvard2015carcinogenicityred

     V. Bouvard et al. Carcinogenicity of consumption of red and processed meat. Lancet Oncol, 16(16):1599-600, 2015. doi:10.1016/S1470-2045(15)00444-1 Evidence: Not graded (guideline)

     Verified 2026-09-26 · PMID 26514947 · DOI 10.1016/S1470-2045(15)00444-1

     • Wiki: Dietary patterns
     • Wiki: Colon health
     • Wiki: Digestive and oral health (section)
     • Deep dive: The 8 things that matter most on your plate
     • Deep dive: The 9 things that matter most for your colon
     • Deep dive: Vegan, vegetarian, omnivore, carnivore: what the labels actually buy you
     • Quiz: Gut & colon health

102. boyd2007mammographicdensity

     N. F. Boyd et al. Mammographic density and the risk and detection of breast cancer. N Engl J Med, 356(3):227-36, 2007. doi:10.1056/NEJMoa062790 Evidence: Moderate

     Verified 2026-09-26 · PMID 17229950 · DOI 10.1056/NEJMoa062790

     • What Matters: What changes breast cancer odds

103. bretthauer2022colonoscopyscreening

     M. Bretthauer et al. Effect of Colonoscopy Screening on Risks of Colorectal Cancer and Related Death. N Engl J Med, 387(17):1547-1556, 2022. doi:10.1056/NEJMoa2208375 Evidence: High

     Verified 2026-09-29 · PMID 36214590 · DOI 10.1056/NEJMoa2208375

     • Wiki: Colon health

104. brito2014sittingrising

     L. B. Brito et al. Ability to sit and rise from the floor as a predictor of all-cause mortality. Eur J Prev Cardiol, 21(7):892-8, 2014. doi:10.1177/2047487312471759 Evidence: Low

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Flexibility and mobility
     • Wiki: Functional fitness
     • What Matters: Movement: What Matters?
     • Deep dive: Body Check: five at-home tests linked to how long you live

105. brooker2019onlineinvestigation

     H. Brooker et al. An online investigation of the relationship between the frequency of word puzzle use and cognitive function in a large sample of older adults. Int J Geriatr Psychiatry, 34(7):921-931, 2019. doi:10.1002/gps.5033 Evidence: Very low

     Verified 2026-09-26 · PMID 30443984 · DOI 10.1002/gps.5033

     • Wiki: Cognitive aging
     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

106. brooker2019relationshipbetween

     H. Brooker et al. The relationship between the frequency of number-puzzle use and baseline cognitive function in a large online sample of adults aged 50 and over. Int J Geriatr Psychiatry, 34(7):932-940, 2019. doi:10.1002/gps.5085 Evidence: Very low

     Verified 2026-09-26 · PMID 30746778 · DOI 10.1002/gps.5085

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Deep dive: How to lower your cognitive age: every habit with a number in years

107. brooks2006napduration

     A. Brooks and L. Lack. A brief afternoon nap following nocturnal sleep restriction: which nap duration is most recuperative?. Sleep, 29(6):831-40, 2006. doi:10.1093/sleep/29.6.831 Evidence: Very low

     Verified 2026-09-29 · PMID 16796222 · DOI 10.1093/sleep/29.6.831

     • Wiki: Naps

108. brown2009adversechildhood

     D. W. Brown et al. Adverse childhood experiences and the risk of premature mortality. Am J Prev Med, 37(5):389-96, 2009. doi:10.1016/j.amepre.2009.06.021 Evidence: Low

     Verified 2026-09-26 · PMID 19840693 · DOI 10.1016/j.amepre.2009.06.021

     • Wiki: Adverse childhood experiences
     • Deep dive: Adverse childhood experiences: what an ACE score predicts, and what still helps now

109. brunt2016passiveheat

     V. E. Brunt et al. Passive heat therapy improves endothelial function, arterial stiffness and blood pressure in sedentary humans. J Physiol, 594(18):5329-42, 2016. doi:10.1113/jp272453 Evidence: Low

     Verified 2026-09-27 · PMID 27270841 · DOI 10.1113/jp272453

     • Wiki: Heat exposure
     • Deep dive: Are hot tubs good for your health and longevity?

110. brzezinski2005melatonin17

     A. Brzezinski et al. Effects of exogenous melatonin on sleep: a meta-analysis. Sleep Med Rev, 9(1):41-50, 2005. doi:10.1016/j.smrv.2004.06.004 Evidence: Moderate

     Verified 2026-09-26 · PMID 15649737 · DOI 10.1016/j.smrv.2004.06.004

     • Wiki: Melatonin (supplement)
     • What Matters: What actually moves sleep quality
     • What Matters: The healthiest habits, ranked

111. bubu2017sleepproblems

     O. M. Bubu et al. Sleep, Cognitive impairment, and Alzheimer's disease: A Systematic Review and Meta-Analysis. Sleep, 40(1), 2017. doi:10.1093/sleep/zsw032 Evidence: High

     Verified 2026-09-26 · PMID 28364458 · DOI 10.1093/sleep/zsw032

     • What Matters: What raises dementia risk most
     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • What Matters: Factors behind Alzheimer’s death risk
     • What Matters: The healthiest habits, ranked

112. buffey2022postmeal

     A. J. Buffey et al. The Acute Effects of Interrupting Prolonged Sitting Time in Adults with Standing and Light-Intensity Walking on Biomarkers of Cardiometabolic Health in Adults: A Systematic Review and Meta-analysis. Sports Med, 52(8):1765-1787, 2022. doi:10.1007/s40279-022-01649-4 Evidence: Moderate

     Verified 2026-09-26 · PMID 35147898 · DOI 10.1007/s40279-022-01649-4

     • Wiki: Sedentary time
     • Wiki: Metabolic health and type 2 diabetes
     • What Matters: Movement: What Matters?
     • Deep dive: The 8 things that matter most for your metabolism

113. bull2020who

     F. C. Bull et al. World Health Organization 2020 guidelines on physical activity and sedentary behaviour. Br J Sports Med, 54(24):1451-1462, 2020. doi:10.1136/bjsports-2020-102955 Evidence: Not graded (guideline)

     Verified 2026-09-28 · PMID 33239350 · DOI 10.1136/bjsports-2020-102955

     • Wiki: Exercise and longevity
     • Wiki: Zone 2 training
     • Wiki: High-intensity interval training
     • Wiki: Resistance training
     • Wiki: Sarcopenia
     • Wiki: Sedentary time
     • Wiki: Exercise (section)
     • Wiki: Cardio and aerobic fitness (section)
     • Wiki: Strength and muscle (section)
     • Wiki: Everyday movement (section)

114. buysse1989pittsburgh

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     Instrument-definition paper cited for the PSQI scoring cut-off (global score >5); not an outcome claim, left untiered.

     • Wiki: Sleep quality
     • What Matters: What actually moves sleep quality

115. byun2018gaba

     J. I. Byun et al. Safety and Efficacy of Gamma-Aminobutyric Acid from Fermented Rice Germ in Patients with Insomnia Symptoms: A Randomized, Double-Blind Trial. J Clin Neurol, 14(3):291-295, 2018. doi:10.3988/jcn.2018.14.3.291 Evidence: Low

     Verified 2026-09-22 · PMID 29856155 · DOI 10.3988/jcn.2018.14.3.291

     PR #555 audit: the original PMID (29629536) resolved to an unrelated ALS/CMT case report; corrected to 29856155.

     • Wiki: GABA (supplement)

116. caffeine2025restedadults

     K. Kløve and A. Petersen. A systematic review and meta-analysis of the acute effect of caffeine on attention. Psychopharmacology, 242(9):1909-1930, 2025. doi:10.1007/s00213-025-06775-1 Evidence: High

     Verified 2026-09-26 · PMID 40335666 · DOI 10.1007/s00213-025-06775-1

     • What Matters: What stretches, or shreds, attention

117. calle2003overweightobesity

     E. E. Calle et al. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med, 348(17):1625-38, 2003. doi:10.1056/NEJMoa021423 Evidence: Low

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     • What Matters: Habits that change cancer death risk

118. cannon2015ezetimibe

     C. P. Cannon et al. Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes. N Engl J Med, 372(25):2387-97, 2015. doi:10.1056/NEJMoa1410489 Evidence: Moderate

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     • Wiki: Cholesterol
     • Deep dive: The 9 things that matter most for your cholesterol

119. cao2011bodymass

     Y. Cao and J. Ma. Body mass index, prostate cancer-specific mortality, and biochemical recurrence: a systematic review and meta-analysis. Cancer Prev Res (Phila), 4(4):486-501, 2011. doi:10.1158/1940-6207.CAPR-10-0229 Evidence: High

     Verified 2026-09-26 · PMID 21233290 · DOI 10.1158/1940-6207.CAPR-10-0229

     • What Matters: Levers on prostate cancer death risk

120. cappuccio2010quantityquality

     F. P. Cappuccio et al. Quantity and quality of sleep and incidence of type 2 diabetes: a systematic review and meta-analysis. Diabetes Care, 33(2):414-20, 2010. doi:10.2337/dc09-1124 Evidence: High

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     • Wiki: Metabolic health and type 2 diabetes
     • What Matters: What moves diabetes death odds

121. cappuccio2010sleep

     F. P. Cappuccio et al. Sleep duration and all-cause mortality: a systematic review and meta-analysis of prospective studies. Sleep, 33(5):585-92, 2010. doi:10.1093/sleep/33.5.585 Evidence: Moderate

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     • Wiki: Sleep physiology
     • Wiki: Sleep duration and mortality
     • Wiki: Sleep (section)
     • What Matters: What sleep does to how long you live
     • Deep dive: The 8 things that matter most for your sleep
     • Deep dive: The 7 things to know about coffee, tea, and energy drinks
     • Deep dive: How sleep affects how long you live
     • Quiz: Sleep
     • Quiz: Sleep check
     • What Matters: What Affects Lifespan the Most
     • What Matters: The healthiest habits, ranked

122. cappuccio2011sleepduration

     F. P. Cappuccio et al. Sleep duration predicts cardiovascular outcomes: a systematic review and meta-analysis of prospective studies. Eur Heart J, 32(12):1484-92, 2011. doi:10.1093/eurheartj/ehr007 Evidence: High

     Verified 2026-09-26 · PMID 21300732 · DOI 10.1093/eurheartj/ehr007

     • Wiki: Sleep physiology
     • Wiki: Sleep duration and mortality
     • What Matters: Habits that swing heart-disease death risk

123. carrascomarin2025fourdietary

     F. Carrasco-Marín et al. Adherence to four dietary indices and the risk of all-cause and cause-specific dementia: Findings from the UK Biobank study. Diabetes Obes Metab, 27(10):5612-5621, 2025. doi:10.1111/dom.16609 Evidence: Low

     Verified 2026-09-26 · PMID 40667707 · DOI 10.1111/dom.16609

     • Deep dive: Plants and your brain: what the vegetarian, Mediterranean and MIND studies really show about dementia

124. carskadon2015normalsleep

     M. A. Carskadon and W. C. Dement. Normal Human Sleep. Principles and Practice of Sleep Medicine, 15-24.e3, 2015. doi:10.1016/B978-0-323-24288-2.00002-7 Evidence: Not graded (review)

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     PR #555 audit: original citation had no working link at all (blank/broken); this DOI was found and confirmed to resolve to the named chapter.

     • Wiki: Sleep physiology
     • Wiki: Sleep (section)

125. castillo2012obesitybut

     J. J. Castillo et al. Obesity but not overweight increases the incidence and mortality of leukemia in adults: a meta-analysis of prospective cohort studies. Leuk Res, 36(7):868-75, 2012. doi:10.1016/j.leukres.2011.12.020 Evidence: Moderate

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     • What Matters: What moves blood-cancer death risk

126. caveroredondo2019dairy

     I. Cavero-Redondo et al. Milk and Dairy Product Consumption and Risk of Mortality: An Overview of Systematic Reviews and Meta-Analyses. Adv Nutr, 10(suppl_2):S97-S104, 2019. doi:10.1093/advances/nmy128 Evidence: Moderate

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     • Wiki: Dairy overall

127. cavon2026multivariatedeterminants

     J. Cavon et al. Multivariate determinants of wearable-measured sleep quality across a large observational cohort: roles of physical activity, gut microbiome, blood analytes, and lifestyle factors. medRxiv, 2026. doi:10.64898/2026.05.27.26354250 Evidence: Very low

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Deep dive: What matters most for high-quality sleep

128. cdc2023heartdisease

     CDC / National Center for Health Statistics. Heart Disease and Stroke Facts and Statistics. CDC/NCHS, 2023. Evidence: Not graded (statistics)

     Verified 2026-09-26

     Regex-only miss (year was already in the original label's parenthetical '2023 data'); no URL change needed. Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Deep dive: Are hot tubs good for your health and longevity?
     • What Matters: What Affects Lifespan the Most

129. cdcnaaboutcdc

     CDC. About the CDC-Kaiser ACE Study. CDC. Evidence: Not graded (reference page)

     Verified 2026-09-26

     Continuously-updated agency resource page, no single publication year stated. Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Deep dive: Adverse childhood experiences: what an ACE score predicts, and what still helps now

130. cdcnachronickidney

     CDC. Chronic Kidney Disease in the United States: Data and Research. CDC. Evidence: Not graded (statistics)

     Verified 2026-09-26

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Skin aging
     • Deep dive: What your eyebags are actually telling you about your health

131. cdcnadiabetesdata

     CDC. Diabetes Data and Research. CDC. Evidence: Not graded (statistics)

     Verified 2026-09-26

     Continuously-updated data hub, no single publication year stated. Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Deep dive: The 9 factors that decide your type 2 diabetes risk

132. cdcnvsr2022lifeexpectancy

     National Center for Health Statistics. National Vital Statistics Reports, Vol. 74 No. 2: U.S. life expectancy. CDC National Vital Statistics System, 2022. Evidence: Not graded (statistics)

     Verified 2026-09-26

     PR #589 confirmed this is the specific report PDF (not a homepage); automated re-fetch here got a 403 (bot-block), consistent with a real, working government page.

     • Quiz: Background
     • What Matters: What Affects Lifespan the Most

133. cdcwonder2023overdose

     CDC WONDER. Underlying Cause of Death, 1999-2023 (ICD-10 query tool). CDC National Center for Health Statistics, 2023. Evidence: Not graded (statistics)

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     PR #589 confirmed this is the specific query tool page (not a homepage); automated re-fetch here got a 403 (bot-block), consistent with a real, working government page.

     • Quiz: Drugs & substances
     • What Matters: Causes of death (population baselines)
     • What Matters: What Affects Lifespan the Most
     • What Matters: The healthiest habits, ranked

134. cecchini2024alcoholintake

     M. Cecchini et al. Alcohol Intake and Risk of Hypertension: A Systematic Review and Dose-Response Meta-Analysis of Nonexperimental Cohort Studies. Hypertension, 81(8):1701-1715, 2024. doi:10.1161/hypertensionaha.124.22703 Evidence: High

     Verified 2026-09-27 · PMID 38864208 · DOI 10.1161/hypertensionaha.124.22703

     • Wiki: Alcohol
     • What Matters: Levers on hypertensive disease deaths

135. cedeno2021officeco2

     J. G. C. Laurent et al. Associations between Acute Exposures to PM(2.5) and Carbon Dioxide Indoors and Cognitive Function in Office Workers: A Multicountry Longitudinal Prospective Observational Study. Environ Res Lett, 16(9):094047, 2021. doi:10.1088/1748-9326/ac1bd8 Evidence: Low

     Verified 2026-09-27 · PMID 35330988 · DOI 10.1088/1748-9326/ac1bd8

     • What Matters: What stretches, or shreds, attention

136. celismorales2017activecommuting

     C. A. Celis-Morales et al. Association between active commuting and incident cardiovascular disease, cancer, and mortality: prospective cohort study. BMJ, 357:j1456, 2017. doi:10.1136/bmj.j1456 Evidence: Low

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Sports and active hobbies
     • What Matters: Movement: What Matters?
     • Deep dive: The sports that add the most years, ranked

137. celismorales2018gripstrength

     C. A. Celis-Morales et al. Associations of grip strength with cardiovascular, respiratory, and cancer outcomes and all cause mortality: prospective cohort study of half a million UK Biobank participants. BMJ, 361:k1651, 2018. doi:10.1136/bmj.k1651 Evidence: Low

     Verified 2026-09-28 · PMID 29739772 · DOI 10.1136/bmj.k1651

     • Wiki: Grip strength

138. cerhan2014waistcircumference

     J. R. Cerhan et al. A pooled analysis of waist circumference and mortality in 650,000 adults. Mayo Clin Proc, 89(3):335-45, 2014. doi:10.1016/j.mayocp.2013.11.011 Evidence: High

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     • Wiki: Metabolic health and type 2 diabetes
     • Wiki: Body weight
     • Deep dive: The 8 things that matter most for your metabolism
     • Deep dive: How much is the extra weight actually costing you?
     • Quiz: Body weight
     • Quiz: Weight check

139. chan1994obesityfat

     J. M. Chan et al. Obesity, fat distribution, and weight gain as risk factors for clinical diabetes in men. Diabetes Care, 17(9):961-9, 1994. doi:10.2337/diacare.17.9.961 Evidence: Low

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     • What Matters: What moves diabetes death odds

140. chan2011redprocessed

     D. S. Chan et al. Red and processed meat and colorectal cancer incidence: meta-analysis of prospective studies. PLoS One, 6(6):e20456, 2011. doi:10.1371/journal.pone.0020456 Evidence: High

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     • Wiki: Dietary patterns
     • What Matters: What changes bowel cancer death risk

141. chandrasekhar2012ashwagandha

     K. Chandrasekhar, J. Kapoor, and S. Anishetty. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian J Psychol Med, 34(3):255-262, 2012. doi:10.4103/0253-7176.106022 Evidence: Low

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     • Wiki: Ashwagandha (supplement)

142. chang2015screenslight

     A. M. Chang et al. Evening use of light-emitting eReaders negatively affects sleep, circadian timing, and next-morning alertness. Proc Natl Acad Sci U S A, 112(4):1232-7, 2015. doi:10.1073/pnas.1418490112 Evidence: Low

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     • Wiki: Sleep physiology
     • Wiki: Insomnia
     • Wiki: Sleep quality
     • What Matters: What actually moves sleep quality
     • What Matters: What stretches, or shreds, attention
     • Deep dive: What matters most for high-quality sleep
     • Deep dive: Bryan Johnson's Ten Sleep Power Laws: what each one asks and how strong the evidence is
     • Deep dive: Top 10 insomnia remedies, ranked by the evidence
     • What Matters: The healthiest habits, ranked

143. chang2020improvedoral

     Y. Chang et al. Improved oral hygiene care is associated with decreased risk of occurrence for atrial fibrillation and heart failure: A nationwide population-based cohort study. Eur J Prev Cardiol, 27(17):1835-1845, 2020. doi:10.1177/2047487319886018 Evidence: Low

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Oral health
     • Deep dive: Does oral care actually affect how long you live?

144. chapman2011adversechildhood

     D. P. Chapman et al. Adverse childhood experiences and sleep disturbances in adults. Sleep Med, 12(8):773-9, 2011. doi:10.1016/j.sleep.2011.03.013 Evidence: Very low

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     • Wiki: Adverse childhood experiences
     • Deep dive: Adverse childhood experiences: what an ACE score predicts, and what still helps now

145. cheah2021ashwagandhasleep

     K. L. Cheah et al. Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis. PLoS One, 16(9):e0257843, 2021. doi:10.1371/journal.pone.0257843 Evidence: Low

     Verified 2026-09-28 · PMID 34559859 · DOI 10.1371/journal.pone.0257843

     • Wiki: Supplements (section)
     • Wiki: Ashwagandha (supplement)
     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

146. chen2012excessbody

     Y. Chen et al. Excess body weight and the risk of primary liver cancer: an updated meta-analysis of prospective studies. Eur J Cancer, 48(14):2137-45, 2012. doi:10.1016/j.ejca.2012.02.063 Evidence: Moderate

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     • What Matters: Habits behind liver cancer death risk

147. chen2013bodymass

     Y. Chen et al. Body mass index and risk of gastric cancer: a meta-analysis of a population with more than ten million from 24 prospective studies. Cancer Epidemiol Biomarkers Prev, 22(8):1395-408, 2013. doi:10.1158/1055-9965.EPI-13-0042 Evidence: High

     Verified 2026-09-26 · PMID 23697611 · DOI 10.1158/1055-9965.EPI-13-0042

     • What Matters: What raises stomach cancer death risk

148. chen2015familyhistory

     T. Chen et al. Family history of esophageal cancer increases the risk of esophageal squamous cell carcinoma. Sci Rep, 5:16038, 2015. doi:10.1038/srep16038 Evidence: Low

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     • What Matters: Factors that swing esophageal cancer deaths

149. chen2024asb

     Z. Chen et al. Artificially sweetened beverage consumption and all-cause and cause-specific mortality: an updated systematic review and dose-response meta-analysis of prospective cohort studies. Nutr J, 23(1):86, 2024. doi:10.1186/s12937-024-00985-7 Evidence: Moderate

     Verified 2026-10-01 · PMID 39085903 · DOI 10.1186/s12937-024-00985-7

     • Wiki: Diet drinks
     • What Matters: Foods ranked for longevity
     • Deep dive: Diet soda vs regular soda vs water: what the evidence shows

150. chen2024globalprevalence

     Y. C. Chen et al. Global Prevalence of Helicobacter pylori Infection and Incidence of Gastric Cancer Between 1980 and 2022. Gastroenterology, 166(4):605-619, 2024. doi:10.1053/j.gastro.2023.12.022 Evidence: Not graded (statistics)

     Verified 2026-10-04 · PMID 38176660 · DOI 10.1053/j.gastro.2023.12.022

     • Wiki: Helicobacter pylori
     • Deep dive: H. pylori and stomach cancer: what the evidence shows

151. chen2025latelife

     Y. Chen et al. Late-life social activity and subsequent risk of dementia and mild cognitive impairment. Alzheimers Dement, 21(1):e14316, 2025. doi:10.1002/alz.14316 Evidence: Low

     Verified 2026-09-26 · PMID 39727247 · DOI 10.1002/alz.14316

     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

152. chen2025machinelearning

     S. J. Chen et al. Machine learning-assisted optimization of dietary intervention against dementia risk. Nat Hum Behav, 9(11):2313-2326, 2025. doi:10.1038/s41562-025-02255-w Evidence: Low

     Verified 2026-09-26 · PMID 40603580 · DOI 10.1038/s41562-025-02255-w

     • Deep dive: Plants and your brain: what the vegetarian, Mediterranean and MIND studies really show about dementia

153. cherbuin2021optimalblood

     N. Cherbuin et al. Optimal Blood Pressure Keeps Our Brains Younger. Front Aging Neurosci, 13:694982, 2021. doi:10.3389/fnagi.2021.694982 Evidence: Low

     Verified 2026-09-26 · PMID 34675795 · DOI 10.3389/fnagi.2021.694982

     • Wiki: Cognitive aging
     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

154. chesney2014allcause

     E. Chesney, G. M. Goodwin, and S. Fazel. Risks of all-cause and suicide mortality in mental disorders: a meta-review. World Psychiatry, 13(2):153-60, 2014. doi:10.1002/wps.20128 Evidence: Moderate

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     • Wiki: Mental health conditions and lifespan
     • Wiki: Mental health and relationships (section)
     • Deep dive: The mental health conditions that cost the most years, ranked
     • Deep dive: What depression does to a lifespan, treated and untreated
     • Quiz: Mental wellbeing
     • Quiz: Drugs & substances

155. cheungpasitporn2014sugarsweetened

     W. Cheungpasitporn et al. Associations of sugar-sweetened and artificially sweetened soda with chronic kidney disease: a systematic review and meta-analysis. Nephrology (Carlton), 19(12):791-7, 2014. doi:10.1111/nep.12343 Evidence: Moderate

     Verified 2026-09-26 · PMID 25251417 · DOI 10.1111/nep.12343

     Five studies for sugar-sweetened soda; the pooled estimate’s lower bound touches 1.00.

     • What Matters: Factors that swing kidney disease deaths

156. chey2024acgclinical

     W. D. Chey et al. ACG Clinical Guideline: Treatment of Helicobacter pylori Infection. Am J Gastroenterol, 119(9):1730-1753, 2024. doi:10.14309/ajg.0000000000002968 Evidence: Not graded (guideline)

     Verified 2026-10-04 · PMID 39626064 · DOI 10.14309/ajg.0000000000002968

     • Wiki: Helicobacter pylori
     • Deep dive: H. pylori and stomach cancer: what the evidence shows

157. chida2008positivewell

     Y. Chida and A. Steptoe. Positive psychological well-being and mortality: a quantitative review of prospective observational studies. Psychosom Med, 70(7):741-56, 2008. doi:10.1097/PSY.0b013e31818105ba Evidence: Moderate

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     • Wiki: Stress and anxiety
     • Deep dive: The 8 things that matter most for staying calm

158. chihuri2019opioidscrashes

     S. Chihuri and G. Li. Use of Prescription Opioids and Initiation of Fatal 2-Vehicle Crashes. JAMA Netw Open, 2(2):e188081, 2019. doi:10.1001/jamanetworkopen.2018.8081 Evidence: Low

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     • What Matters: Factors that swing accidental deaths

159. chikritzhs2015hasleaning

     T. Chikritzhs et al. Has the leaning tower of presumed health benefits from 'moderate' alcohol use finally collapsed?. Addiction, 110(5):726-7, 2015. doi:10.1111/add.12828 Evidence: Not graded (review)

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     • What Matters: Habits that change cancer death risk
     • What Matters: What moves blood-cancer death risk
     • What Matters: What raises — or cuts — stroke death risk
     • What Matters: What moves diabetes death odds

160. choi2018helicobacterpylori

     I. J. Choi et al. Helicobacter pylori Therapy for the Prevention of Metachronous Gastric Cancer. N Engl J Med, 378(12):1085-1095, 2018. doi:10.1056/NEJMoa1708423 Evidence: Moderate

     Verified 2026-10-04 · PMID 29562147 · DOI 10.1056/NEJMoa1708423

     • Wiki: Helicobacter pylori
     • Deep dive: H. pylori and stomach cancer: what the evidence shows

161. choi2020familyhistory

     I. J. Choi et al. Family History of Gastric Cancer and Helicobacter pylori Treatment. N Engl J Med, 382(5):427-436, 2020. doi:10.1056/NEJMoa1909666 Evidence: Moderate

     Verified 2026-10-04 · PMID 31995688 · DOI 10.1056/NEJMoa1909666

     • Wiki: Helicobacter pylori
     • Deep dive: H. pylori and stomach cancer: what the evidence shows

162. choi2024hearingaid

     J. S. Choi et al. Association between hearing aid use and mortality in adults with hearing loss in the USA: a mortality follow-up study of a cross-sectional cohort. Lancet Healthy Longev, 5(1):e66-e75, 2024. doi:10.1016/s2666-7568(23)00232-5 Evidence: Low

     Verified 2026-09-27 · PMID 38183998 · DOI 10.1016/s2666-7568(23)00232-5

     • Wiki: Hearing and vision loss
     • Deep dive: Are your ears and eyes quietly aging your brain?
     • Quiz: Hearing & vision
     • Quiz: Hearing & vision check

163. christensen2009perceivedage

     K. Christensen et al. Perceived age as clinically useful biomarker of ageing: cohort study. BMJ, 339:b5262, 2009. doi:10.1136/bmj.b5262 Evidence: Low

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     • Wiki: Skin aging
     • Wiki: Skin and hair (section)
     • Deep dive: What your skin is actually telling you about how long you live

164. christoffersen2011xanthelasmataarcus

     M. Christoffersen et al. Xanthelasmata, arcus corneae, and ischaemic vascular disease and death in general population: prospective cohort study. BMJ, 343:d5497, 2011. doi:10.1136/bmj.d5497 Evidence: Low

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     • Wiki: Skin aging
     • Deep dive: What your eyebags are actually telling you about your health

165. christopoulos2022petsurvival

     K. Christopoulos et al. Pet ownership and survival of European older adults. European Journal of Ageing, 19(4):1549-1560, 2022. doi:10.1007/s10433-022-00739-6 Evidence: Low

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     • Wiki: Pet ownership
     • Wiki: Mental health and relationships (section)
     • Deep dive: Does having a pet actually help you live longer?
     • What Matters: What Affects Lifespan the Most

166. chung2016stopbang

     F. Chung, H. R. Abdullah, and P. Liao. STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea. Chest, 149(3):631-8, 2016. doi:10.1378/chest.15-0903 Evidence: Not graded (measurement tool)

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     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

167. chung2018sleephygiene

     K. F. Chung et al. Sleep hygiene education as a treatment of insomnia: a systematic review and meta-analysis. Fam Pract, 35(4):365-375, 2018. doi:10.1093/fampra/cmx122 Evidence: Low

     Verified 2026-10-08 · PMID 29194467 · DOI 10.1093/fampra/cmx122

     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

168. chung2020tea

     M. Chung et al. Dose-Response Relation between Tea Consumption and Risk of Cardiovascular Disease and All-Cause Mortality: A Systematic Review and Meta-Analysis of Population-Based Studies. Adv Nutr, 11(4):790-814, 2020. doi:10.1093/advances/nmaa010 Evidence: Moderate

     Verified 2026-10-01 · PMID 32073596 · DOI 10.1093/advances/nmaa010

     • Wiki: Tea

169. cillekens2025leisureactivity

     B. Cillekens et al. Should workers be physically active after work? Associations of leisure-time physical activity with cardiovascular and all-cause mortality across occupational physical activity levels-An individual participant data meta-analysis. J Sport Health Sci, 14:100987, 2025. doi:10.1016/j.jshs.2024.100987 Evidence: High

     Verified 2026-09-26 · PMID 39277081 · DOI 10.1016/j.jshs.2024.100987

     • What Matters: Movement: What Matters?

170. cipriani2013lithiumsuicide

     A. Cipriani et al. Lithium in the prevention of suicide in mood disorders: updated systematic review and meta-analysis. BMJ, 346:f3646, 2013. doi:10.1136/bmj.f3646 Evidence: Moderate

     Verified 2026-09-26 · PMID 23814104 · DOI 10.1136/bmj.f3646

     • Wiki: Mental health conditions and lifespan
     • Deep dive: The mental health conditions that cost the most years, ranked
     • What Matters: Factors linked to suicide deaths

171. cipriani2018comparativeefficacy

     A. Cipriani et al. Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis. Lancet, 391(10128):1357-1366, 2018. doi:10.1016/S0140-6736(17)32802-7 Evidence: High

     Verified 2026-09-26 · PMID 29477251 · DOI 10.1016/S0140-6736(17)32802-7

     • Wiki: Mental health conditions and lifespan
     • Deep dive: What depression does to a lifespan, treated and untreated

172. clements2019aquariumfish

     H. Clements et al. The effects of interacting with fish in aquariums on human health and well-being: A systematic review. PLOS ONE, 14(7):e0220524, 2019. doi:10.1371/journal.pone.0220524 Evidence: Very low

     Verified 2026-09-27 · PMID 31356652 · DOI 10.1371/journal.pone.0220524

     • Wiki: Pet ownership
     • Deep dive: Does having a pet actually help you live longer?
     • What Matters: What Affects Lifespan the Most

173. coenen2018occupationalphysical

     P. Coenen et al. Do highly physically active workers die early? A systematic review with meta-analysis of data from 193 696 participants. Br J Sports Med, 52(20):1320-1326, 2018. doi:10.1136/bjsports-2017-098540 Evidence: Moderate

     Verified 2026-09-26 · PMID 29760168 · DOI 10.1136/bjsports-2017-098540

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • What Matters: Movement: What Matters?

174. cole2015predictionbrain

     J. H. Cole et al. Prediction of brain age suggests accelerated atrophy after traumatic brain injury. Ann Neurol, 77(4):571-81, 2015. doi:10.1002/ana.24367 Evidence: Very low

     Verified 2026-09-26 · PMID 25623048 · DOI 10.1002/ana.24367

     • Wiki: Cognitive aging
     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years

175. collaborative1996breastcancer

     Collaborative Group on Hormonal Factors in Breast Cancer. Breast cancer and hormonal contraceptives: collaborative reanalysis of individual data on 53 297 women with breast cancer and 100 239 women without breast cancer from 54 epidemiological studies. Lancet, 347(9017):1713-27, 1996. doi:10.1016/s0140-6736(96)90806-5 Evidence: High

     Verified 2026-09-26 · PMID 8656904 · DOI 10.1016/s0140-6736(96)90806-5

     • What Matters: What changes breast cancer odds

176. collaborative2001familialbreast

     Collaborative Group on Hormonal Factors in Breast Cancer. Familial breast cancer: collaborative reanalysis of individual data from 52 epidemiological studies including 58,209 women with breast cancer and 101,986 women without the disease. Lancet, 358(9291):1389-99, 2001. doi:10.1016/S0140-6736(01)06524-2 Evidence: High

     Verified 2026-09-26 · PMID 11705483 · DOI 10.1016/S0140-6736(01)06524-2

     • Wiki: Family history and genetics
     • What Matters: What changes breast cancer odds

177. collaborative2002breastcancer

     Collaborative Group on Hormonal Factors in Breast Cancer. Breast cancer and breastfeeding: collaborative reanalysis of individual data from 47 epidemiological studies in 30 countries, including 50302 women with breast cancer and 96973 women without the disease. Lancet, 360(9328):187-95, 2002. doi:10.1016/S0140-6736(02)09454-0 Evidence: High

     Verified 2026-09-26 · PMID 12133652 · DOI 10.1016/S0140-6736(02)09454-0

     • What Matters: What changes breast cancer odds

178. collaborative2008ovariancancer

     Collaborative Group on Epidemiological Studies of Ovarian Cancer et al. Ovarian cancer and oral contraceptives: collaborative reanalysis of data from 45 epidemiological studies including 23,257 women with ovarian cancer and 87,303 controls. Lancet, 371(9609):303-14, 2008. doi:10.1016/S0140-6736(08)60167-1 Evidence: High

     Verified 2026-09-26 · PMID 18294997 · DOI 10.1016/S0140-6736(08)60167-1

     • What Matters: What raises ovarian cancer death risk

179. collaborative2012menarchemenopause

     Collaborative Group on Hormonal Factors in Breast Cancer. Menarche, menopause, and breast cancer risk: individual participant meta-analysis, including 118 964 women with breast cancer from 117 epidemiological studies. Lancet Oncol, 13(11):1141-51, 2012. doi:10.1016/S1470-2045(12)70425-4 Evidence: High

     Verified 2026-09-26 · PMID 23084519 · DOI 10.1016/S1470-2045(12)70425-4

     • What Matters: What changes breast cancer odds

180. collaborative2012ovariancancer

     Collaborative Group on Epidemiological Studies of Ovarian Cancer. Ovarian cancer and body size: individual participant meta-analysis including 25,157 women with ovarian cancer from 47 epidemiological studies. PLoS Med, 9(4):e1001200, 2012. doi:10.1371/journal.pmed.1001200 Evidence: High

     Verified 2026-09-26 · PMID 22606070 · DOI 10.1371/journal.pmed.1001200

     • What Matters: What raises ovarian cancer death risk

181. collaborative2012ovariancancer2

     Collaborative Group on Epidemiological Studies of Ovarian Cancer et al. Ovarian cancer and smoking: individual participant meta-analysis including 28,114 women with ovarian cancer from 51 epidemiological studies. Lancet Oncol, 13(9):946-56, 2012. doi:10.1016/S1470-2045(12)70322-4 Evidence: High

     Verified 2026-09-26 · PMID 22863523 · DOI 10.1016/S1470-2045(12)70322-4

     • What Matters: What raises ovarian cancer death risk

182. collaborative2015endometrialcancer

     Collaborative Group on Epidemiological Studies on Endometrial Cancer. Endometrial cancer and oral contraceptives: an individual participant meta-analysis of 27 276 women with endometrial cancer from 36 epidemiological studies. Lancet Oncol, 16(9):1061-70, 2015. doi:10.1016/S1470-2045(15)00212-0 Evidence: High

     Verified 2026-09-30 · PMID 26254030 · DOI 10.1016/S1470-2045(15)00212-0

     • What Matters: Habits that change uterine cancer death risk

183. collaborative2015menopausalhormone

     Collaborative Group On Epidemiological Studies Of Ovarian Cancer et al. Menopausal hormone use and ovarian cancer risk: individual participant meta-analysis of 52 epidemiological studies. Lancet, 385(9980):1835-42, 2015. doi:10.1016/S0140-6736(14)61687-1 Evidence: High

     Verified 2026-09-26 · PMID 25684585 · DOI 10.1016/S0140-6736(14)61687-1

     • What Matters: What raises ovarian cancer death risk

184. collaborative2019typetiming

     Collaborative Group on Hormonal Factors in Breast Cancer. Type and timing of menopausal hormone therapy and breast cancer risk: individual participant meta-analysis of the worldwide epidemiological evidence. Lancet, 394(10204):1159-1168, 2019. doi:10.1016/S0140-6736(19)31709-X Evidence: High

     Verified 2026-09-26 · PMID 31474332 · DOI 10.1016/S0140-6736(19)31709-X

     • What Matters: What changes breast cancer odds

185. collin2019regards

     L. J. Collin et al. Association of Sugary Beverage Consumption With Mortality Risk in US Adults: A Secondary Analysis of Data From the REGARDS Study. JAMA Netw Open, 2(5):e193121, 2019. doi:10.1001/jamanetworkopen.2019.3121 Evidence: Low

     Verified 2026-10-01 · PMID 31099861 · DOI 10.1001/jamanetworkopen.2019.3121

     • Wiki: Fruit juice

186. conrad2022autoimmunediseases

     N. Conrad et al. Autoimmune diseases and cardiovascular risk: a population-based study on 19 autoimmune diseases and 12 cardiovascular diseases in 22 million individuals in the UK. Lancet, 400(10354):733-743, 2022. doi:10.1016/S0140-6736(22)01349-6 Evidence: Low

     Verified 2026-09-26 · PMID 36041475 · DOI 10.1016/S0140-6736(22)01349-6

     • What Matters: Habits that swing heart-disease death risk

187. constantinides2023brainageing

     C. Constantinides et al. Brain ageing in schizophrenia: evidence from 26 international cohorts via the ENIGMA Schizophrenia consortium. Mol Psychiatry, 28(3):1201-1209, 2023. doi:10.1038/s41380-022-01897-w Evidence: Very low

     Verified 2026-09-26 · PMID 36494461 · DOI 10.1038/s41380-022-01897-w

     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

188. cooper2010physicalcapability

     R. Cooper et al. Objectively measured physical capability levels and mortality: systematic review and meta-analysis. BMJ, 341:c4467, 2010. doi:10.1136/bmj.c4467 Evidence: High

     Verified 2026-09-28 · PMID 20829298 · DOI 10.1136/bmj.c4467

     • Wiki: Balance training
     • Wiki: Functional fitness
     • Wiki: Balance, mobility and function (section)

189. cornelius2022tobaccouse2020

     M. E. Cornelius et al. Tobacco Product Use Among Adults - United States, 2020. MMWR Morb Mortal Wkly Rep, 71(11):397-405, 2022. doi:10.15585/mmwr.mm7111a1 Evidence: Not graded (statistics)

     Verified 2026-09-26 · PMID 35298455 · DOI 10.15585/mmwr.mm7111a1

     Cited for the cigarettes-per-day mix of daily smokers in NHIS 2020 (1–9: 25.0%, 10–19: 40.7%, 20–29: 27.9%, 30+: 6.4%).

     • Wiki: Smoking
     • What Matters: Your estimated chance of each cause (method)

190. coroneloliveros2025creativeexperiences

     C. Coronel-Oliveros et al. Creative experiences and brain clocks. Nat Commun, 16(1):8336, 2025. doi:10.1038/s41467-025-64173-9 Evidence: Very low

     Verified 2026-09-27 · PMID 41044135 · DOI 10.1038/s41467-025-64173-9

     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

191. cote2012familyhistory

     M. L. Coté et al. Increased risk of lung cancer in individuals with a family history of the disease: a pooled analysis from the International Lung Cancer Consortium. Eur J Cancer, 48(13):1957-68, 2012. doi:10.1016/j.ejca.2012.01.038 Evidence: High

     Verified 2026-09-26 · PMID 22436981 · DOI 10.1016/j.ejca.2012.01.038

     • What Matters: Smoking and the rest: lung cancer death risk

192. coupland2019anticholinergicdrug

     C. A. C. Coupland et al. Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control Study. JAMA Intern Med, 179(8):1084-1093, 2019. doi:10.1001/jamainternmed.2019.0677 Evidence: Low

     Verified 2026-09-26 · PMID 31233095 · DOI 10.1001/jamainternmed.2019.0677

     • What Matters: What raises dementia risk most
     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • What Matters: Factors behind Alzheimer’s death risk

193. cramer2014yoga

     H. Cramer et al. Effects of yoga on cardiovascular disease risk factors: a systematic review and meta-analysis. Int J Cardiol, 173(2):170-83, 2014. doi:10.1016/j.ijcard.2014.02.017 Evidence: Moderate

     Verified 2026-09-28 · PMID 24636547 · DOI 10.1016/j.ijcard.2014.02.017

     • Wiki: Yoga and tai chi
     • Wiki: Everyday movement (section)

194. cruzalmeida2019chronicpain

     Y. Cruz-Almeida et al. Chronic pain is associated with a brain aging biomarker in community-dwelling older adults. Pain, 160(5):1119-1130, 2019. doi:10.1097/j.pain.0000000000001491 Evidence: Very low

     Verified 2026-09-26 · PMID 31009418 · DOI 10.1097/j.pain.0000000000001491

     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years

195. cruzjentoft2019sarcopenia

     A. J. Cruz-Jentoft et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing, 48(1):16-31, 2019. doi:10.1093/ageing/afy169 Evidence: Not graded (guideline)

     Verified 2026-09-28 · PMID 30312372 · DOI 10.1093/ageing/afy169

     Guideline / consensus statement; left untiered per citations.md.

     • Wiki: Muscle mass
     • Wiki: Grip strength
     • Wiki: Sarcopenia

196. ctt2010ldllowering

     Cholesterol Treatment Trialists’ (CTT) Collaboration et al. Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials. Lancet, 376(9753):1670-81, 2010. doi:10.1016/S0140-6736(10)61350-5 Evidence: High

     Verified 2026-09-26 · PMID 21067804 · DOI 10.1016/S0140-6736(10)61350-5

     • Wiki: Cholesterol
     • Wiki: Heart and metabolic health (section)
     • Deep dive: The 9 things that matter most for your cholesterol
     • Quiz: Heart health
     • Quiz: Cholesterol check
     • What Matters: Habits that swing heart-disease death risk

197. cuijpers2013mortalitymajor

     P. Cuijpers et al. Differential mortality rates in major and subthreshold depression: meta-analysis of studies that measured both. Br J Psychiatry, 202(1):22-7, 2013. doi:10.1192/bjp.bp.112.112169 Evidence: Moderate

     Verified 2026-09-27 · PMID 23284149 · DOI 10.1192/bjp.bp.112.112169

     • Wiki: Mental health conditions and lifespan
     • Deep dive: What depression does to a lifespan, treated and untreated

198. cuijpers2014excessmortality

     P. Cuijpers et al. Comprehensive meta-analysis of excess mortality in depression in the general community versus patients with specific illnesses. Am J Psychiatry, 171(4):453-62, 2014. doi:10.1176/appi.ajp.2013.13030325 Evidence: Moderate

     Verified 2026-09-26 · PMID 24434956 · DOI 10.1176/appi.ajp.2013.13030325

     • Wiki: Mental health conditions and lifespan
     • Deep dive: What depression does to a lifespan, treated and untreated

199. cummings2003seatbelt

     P. Cummings, J. D. Wells, and F. P. Rivara. Estimating seat belt effectiveness using matched-pair cohort methods. Accid Anal Prev, 35(1):143-9, 2003. doi:10.1016/s0001-4575(01)00087-2 Evidence: Low

     Verified 2026-09-26 · PMID 12479905 · DOI 10.1016/s0001-4575(01)00087-2

     • What Matters: Factors that swing accidental deaths

200. cummings2020pottedplants

     B. E. Cummings and M. S. Waring. Potted plants do not improve indoor air quality: a review and analysis of reported VOC removal efficiencies. Journal of Exposure Science & Environmental Epidemiology, 30(2):253-261, 2020. doi:10.1038/s41370-019-0175-9 Evidence: Moderate

     Verified 2026-09-27 · PMID 31695112 · DOI 10.1038/s41370-019-0175-9

     • Deep dive: Does having a pet actually help you live longer?

201. curtin2025injurydeathtrends

     Curtin SC. Trends in death rates for leading methods of injury: United States, 2003–2023 (NCHS Data Brief No. 526). National Center for Health Statistics, 2025. Evidence: Not graded (statistics)

     Verified 2026-09-26

     Cited for 2023 unintentional-injury deaths by method: 222,698 total; drug overdose 97,231, falls 47,026, motor-vehicle traffic 43,273.

     • Wiki: Road safety
     • Wiki: Environment and safety (section)
     • What Matters: Your estimated chance of each cause (method)

202. dadoun2013mortalityrheumatoid

     S. Dadoun et al. Mortality in rheumatoid arthritis over the last fifty years: systematic review and meta-analysis. Joint Bone Spine, 80(1):29-33, 2013. doi:10.1016/j.jbspin.2012.02.005 Evidence: High

     Verified 2026-09-26 · PMID 22459416 · DOI 10.1016/j.jbspin.2012.02.005

     • Wiki: Inflammation and aging
     • Deep dive: The 9 things that matter most for taming inflammation
     • Quiz: Preventive care

203. dam2013smokingrisk

     M. K. Dam et al. Smoking and risk of liver cirrhosis: a population-based cohort study. Scand J Gastroenterol, 48(5):585-91, 2013. doi:10.3109/00365521.2013.777469 Evidence: Low

     Verified 2026-09-26 · PMID 23506154 · DOI 10.3109/00365521.2013.777469

     • What Matters: Factors that swing liver disease deaths

204. danese2007childhoodmaltreatment

     A. Danese et al. Childhood maltreatment predicts adult inflammation in a life-course study. Proc Natl Acad Sci U S A, 104(4):1319-24, 2007. doi:10.1073/pnas.0610362104 Evidence: Low

     Verified 2026-09-26 · PMID 17229839 · DOI 10.1073/pnas.0610362104

     • Wiki: Adverse childhood experiences
     • Wiki: Inflammation and aging
     • Deep dive: Adverse childhood experiences: what an ACE score predicts, and what still helps now

205. darby2005radonhomes

     S. Darby et al. Radon in homes and risk of lung cancer: collaborative analysis of individual data from 13 European case-control studies. BMJ, 330(7485):223, 2005. doi:10.1136/bmj.38308.477650.63 Evidence: High

     Verified 2026-09-26 · PMID 15613366 · DOI 10.1136/bmj.38308.477650.63

     • What Matters: Smoking and the rest: lung cancer death risk

206. darooghegimofrad2020potato

     M. Darooghegi Mofrad et al. Potato consumption and risk of all cause, cancer and cardiovascular mortality: a systematic review and dose-response meta-analysis of prospective cohort studies. Crit Rev Food Sci Nutr, 60(7):1063-1076, 2020. doi:10.1080/10408398.2018.1557102 Evidence: High

     Verified 2026-10-01 · PMID 30638040 · DOI 10.1080/10408398.2018.1557102

     • Wiki: Potatoes

207. darooghegimofrad2022eggs

     M. Darooghegi Mofrad et al. Egg and Dietary Cholesterol Intake and Risk of All-Cause, Cardiovascular, and Cancer Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies. Front Nutr, 9:878979, 2022. doi:10.3389/fnut.2022.878979 Evidence: Moderate

     Verified 2026-10-01 · PMID 35711545 · DOI 10.3389/fnut.2022.878979

     • Wiki: Eggs

208. dattilo1992weightloss

     A. M. Dattilo and P. M. Kris-Etherton. Effects of weight reduction on blood lipids and lipoproteins: a meta-analysis. Am J Clin Nutr, 56(2):320-8, 1992. doi:10.1093/ajcn/56.2.320 Evidence: Moderate

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     • Wiki: Cholesterol
     • Deep dive: The 9 things that matter most for your cholesterol

209. daviet2022associationsbetween

     R. Daviet et al. Associations between alcohol consumption and gray and white matter volumes in the UK Biobank. Nat Commun, 13(1):1175, 2022. doi:10.1038/s41467-022-28735-5 Evidence: Very low

     Verified 2026-09-27 · PMID 35246521 · DOI 10.1038/s41467-022-28735-5

     • Wiki: Alcohol
     • Wiki: Cognitive aging
     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

210. de2008hepatitisc

     S. de Sanjose et al. Hepatitis C and non-Hodgkin lymphoma among 4784 cases and 6269 controls from the International Lymphoma Epidemiology Consortium. Clin Gastroenterol Hepatol, 6(4):451-8, 2008. doi:10.1016/j.cgh.2008.02.011 Evidence: High

     Verified 2026-09-26 · PMID 18387498 · DOI 10.1016/j.cgh.2008.02.011

     • What Matters: What moves blood-cancer death risk

211. de2011sugarsweetened

     L. de Koning et al. Sugar-sweetened and artificially sweetened beverage consumption and risk of type 2 diabetes in men. Am J Clin Nutr, 93(6):1321-7, 2011. doi:10.3945/ajcn.110.007922 Evidence: Low

     Verified 2026-09-26 · PMID 21430119 · DOI 10.3945/ajcn.110.007922

     • What Matters: What moves diabetes death odds

212. dean2024professionalsleeper

     G. Dean. Bryan Johnson's Free Guide to Becoming a Professional Sleeper. NAD.com, 2024. Evidence: Not graded (news release)

     Verified 2026-10-02

     Source of the 10 sleep laws list (Bryan Johnson's sleep protocol, Don't Die). Published 2024-04-03.

     • Deep dive: Bryan Johnson's Ten Sleep Power Laws: what each one asks and how strong the evidence is
     • Quiz: Bryan Johnson's Ten Sleep Power Laws

213. debras2022sweetenerscancer

     C. Debras et al. Artificial sweeteners and cancer risk: Results from the NutriNet-Santé population-based cohort study. PLoS Med, 19(3):e1003950, 2022. doi:10.1371/journal.pmed.1003950 Evidence: Low

     Verified 2026-10-05 · PMID 35324894 · DOI 10.1371/journal.pmed.1003950

     • Deep dive: Diet soda vs regular soda vs water: what the evidence shows

214. debras2022sweetenerscvd

     C. Debras et al. Artificial sweeteners and risk of cardiovascular diseases: results from the prospective NutriNet-Santé cohort. BMJ, 378:e071204, 2022. doi:10.1136/bmj-2022-071204 Evidence: Low

     Verified 2026-10-05 · PMID 36638072 · DOI 10.1136/bmj-2022-071204

     • Deep dive: Diet soda vs regular soda vs water: what the evidence shows

215. degenhardt2019opioiddependence

     L. Degenhardt et al. Global patterns of opioid use and dependence: harms to populations, interventions, and future action. Lancet, 394(10208):1560-1579, 2019. doi:10.1016/S0140-6736(19)32229-9 Evidence: Moderate

     Verified 2026-09-28 · PMID 31657732 · DOI 10.1016/S0140-6736(19)32229-9

     • Quiz: Drugs & substances

216. dehghan2018pure

     M. Dehghan et al. Association of dairy intake with cardiovascular disease and mortality in 21 countries from five continents (PURE): a prospective cohort study. Lancet, 392(10161):2288-2297, 2018. doi:10.1016/S0140-6736(18)31812-9 Evidence: Moderate

     Verified 2026-10-01 · PMID 30217460 · DOI 10.1016/S0140-6736(18)31812-9

     • Wiki: Dairy overall

217. delange2005shelterin

     T. de Lange. Shelterin: the protein complex that shapes and safeguards human telomeres. Genes Dev, 19(18):2100-10, 2005. doi:10.1101/gad.1346005 Evidence: Very low

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     • Wiki: Telomeres

218. delia2012habitualsalt

     L. D'Elia et al. Habitual salt intake and risk of gastric cancer: a meta-analysis of prospective studies. Clin Nutr, 31(4):489-98, 2012. doi:10.1016/j.clnu.2012.01.003 Evidence: High

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     Migration note: this citation used a double-quoted label literal (the only one in the corpus, needed for the apostrophe in "D'Elia") that the single-quote-only migration regex silently skipped; added by hand after the CI gate caught the resulting dead per-level citation.

     • Wiki: Helicobacter pylori
     • Deep dive: H. pylori and stomach cancer: what the evidence shows
     • What Matters: What raises stomach cancer death risk

219. demicheli2018influenzavaccines

     V. Demicheli et al. Vaccines for preventing influenza in the elderly. Cochrane Database Syst Rev, 2(2):CD004876, 2018. doi:10.1002/14651858.CD004876.pub4 Evidence: Low

     Verified 2026-09-26 · PMID 29388197 · DOI 10.1002/14651858.CD004876.pub4

     Cochrane review of 8 RCTs in adults 65+; low-certainty evidence for influenza, trials underpowered for pneumonia and deaths.

     • What Matters: Factors that swing flu and pneumonia deaths

220. dennis2008sunburnsrisk

     L. K. Dennis et al. Sunburns and risk of cutaneous melanoma: does age matter? A comprehensive meta-analysis. Ann Epidemiol, 18(8):614-27, 2008. doi:10.1016/j.annepidem.2008.04.006 Evidence: High

     Verified 2026-09-26 · PMID 18652979 · DOI 10.1016/j.annepidem.2008.04.006

     • What Matters: Sun and the rest: melanoma death risk

221. dent2018sarcopeniaguidelines

     E. Dent et al. International Clinical Practice Guidelines for Sarcopenia (ICFSR): Screening, Diagnosis and Management. J Nutr Health Aging, 22(10):1148-1161, 2018. doi:10.1007/s12603-018-1139-9 Evidence: Not graded (guideline)

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     Guideline / consensus statement; left untiered per citations.md.

     • Wiki: Sarcopenia
     • Wiki: Strength and muscle (section)

222. descatha2020longworking

     A. Descatha et al. The effect of exposure to long working hours on stroke: A systematic review and meta-analysis from the WHO/ILO Joint Estimates of the Work-related Burden of Disease and Injury. Environ Int, 142:105746, 2020. doi:10.1016/j.envint.2020.105746 Evidence: High

     Verified 2026-09-26 · PMID 32505015 · DOI 10.1016/j.envint.2020.105746

     • What Matters: What raises — or cuts — stroke death risk

223. deshpande2020ashwagandhasleep

     A. Deshpande et al. A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults. Sleep Med, 72:28-36, 2020. doi:10.1016/j.sleep.2020.03.012 Evidence: Low

     Verified 2026-09-22 · PMID 32540634 · DOI 10.1016/j.sleep.2020.03.012

     PR #555 audit: the original PMID (32014539) resolved to an unrelated rat-ECG-telemetry study; corrected to 32540634.

     • Wiki: Ashwagandha (supplement)

224. diaz2017sedentarybouts

     K. M. Diaz et al. Patterns of Sedentary Behavior and Mortality in U.S. Middle-Aged and Older Adults: A National Cohort Study. Ann Intern Med, 167(7):465-475, 2017. doi:10.7326/M17-0212 Evidence: Low

     Verified 2026-09-26 · PMID 28892811 · DOI 10.7326/M17-0212

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Sedentary time
     • What Matters: Movement: What Matters?

225. dijoseph2023physicalactivity

     K. DiJoseph et al. Physical Activity and Risk of Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis. Dig Dis Sci, 68(3):1051-1059, 2023. doi:10.1007/s10620-022-07601-w Evidence: High

     Verified 2026-09-26 · PMID 35767138 · DOI 10.1007/s10620-022-07601-w

     • What Matters: Habits behind liver cancer death risk

226. dimatteo2000depressiontreatment

     M. R. DiMatteo, H. S. Lepper, and T. W. Croghan. Depression is a risk factor for noncompliance with medical treatment: meta-analysis of the effects of anxiety and depression on patient adherence. Arch Intern Med, 160(14):2101-7, 2000. doi:10.1001/archinte.160.14.2101 Evidence: Moderate

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Mental health conditions and lifespan
     • Deep dive: What depression does to a lifespan, treated and untreated

227. ding2014longterm

     M. Ding et al. Long-term coffee consumption and risk of cardiovascular disease: a systematic review and a dose-response meta-analysis of prospective cohort studies. Circulation, 129(6):643-59, 2014. doi:10.1161/CIRCULATIONAHA.113.005925 Evidence: High

     Verified 2026-09-26 · PMID 24201300 · DOI 10.1161/CIRCULATIONAHA.113.005925

     • What Matters: Habits that swing heart-disease death risk

228. ding2015lifestylerisk

     D. Ding et al. Traditional and Emerging Lifestyle Risk Behaviors and All-Cause Mortality in Middle-Aged and Older Adults: Evidence from a Large Population-Based Australian Cohort. PLoS Med, 12(12):e1001917, 2015. doi:10.1371/journal.pmed.1001917 Evidence: Low

     Verified 2026-09-26 · PMID 26645683 · DOI 10.1371/journal.pmed.1001917

     • Wiki: Sleep duration and mortality
     • Deep dive: How sleep affects how long you live

229. ding2019dairy

     M. Ding et al. Associations of dairy intake with risk of mortality in women and men: three prospective cohort studies. BMJ, 367:l6204, 2019. doi:10.1136/bmj.l6204 Evidence: Moderate

     Verified 2026-10-01 · PMID 31776125 · DOI 10.1136/bmj.l6204

     • Wiki: Dairy overall

230. dingus2016naturalisticdriving

     T. A. Dingus et al. Driver crash risk factors and prevalence evaluation using naturalistic driving data. Proc Natl Acad Sci U S A, 113(10):2636-41, 2016. doi:10.1073/pnas.1513271113 Evidence: Low

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Road safety
     • Wiki: Environment and safety (section)
     • Deep dive: The 9 things that matter most for surviving the road
     • Quiz: Safety habits
     • What Matters: Your estimated chance of each cause (method)

231. dinu2017vegetarianvegan

     M. Dinu et al. Vegetarian, vegan diets and multiple health outcomes: A systematic review with meta-analysis of observational studies. Crit Rev Food Sci Nutr, 57(17):3640-3649, 2017. doi:10.1080/10408398.2016.1138447 Evidence: Moderate

     Verified 2026-09-26 · PMID 26853923 · DOI 10.1080/10408398.2016.1138447

     • Wiki: Dietary patterns
     • Deep dive: Vegan, vegetarian, omnivore, carnivore: what the labels actually buy you
     • What Matters: Habits that swing heart-disease death risk

232. dmitrieva2023serumsodium

     N. I. Dmitrieva et al. Middle-age high normal serum sodium as a risk factor for accelerated biological aging, chronic diseases, and premature mortality. EBioMedicine, 87:104404, 2023. doi:10.1016/j.ebiom.2022.104404 Evidence: Low

     Verified 2026-09-26 · PMID 36599719 · DOI 10.1016/j.ebiom.2022.104404

     • Wiki: Hydration
     • Wiki: Diet and nutrition (section)
     • Deep dive: The 7 things worth knowing about hydration
     • Quiz: Diet check

233. doll2004mortalityrelation

     R. Doll et al. Mortality in relation to smoking: 50 years' observations on male British doctors. BMJ, 328(7455):1519, 2004. doi:10.1136/bmj.38142.554479.ae Evidence: Low

     Verified 2026-09-27 · PMID 15213107 · DOI 10.1136/bmj.38142.554479.ae

     • Wiki: Smoking
     • Wiki: Alcohol and tobacco (section)
     • Deep dive: Smoking takes about ten years. Here is what quitting gives back
     • Quiz: Smoking
     • Quiz: Smoking check

234. dominy2019porphyromonasgingivalis

     S. S. Dominy et al. Porphyromonas gingivalis in Alzheimer's disease brains: Evidence for disease causation and treatment with small-molecule inhibitors. Sci Adv, 5(1):eaau3333, 2019. doi:10.1126/sciadv.aau3333 Evidence: Very low

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Oral health
     • Deep dive: Does oral care actually affect how long you live?

235. douaud2013preventingalzheimer

     G. Douaud et al. Preventing Alzheimer's disease-related gray matter atrophy by B-vitamin treatment. Proc Natl Acad Sci U S A, 110(23):9523-8, 2013. doi:10.1073/pnas.1301816110 Evidence: Low

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     • Deep dive: Plants and your brain: what the vegetarian, Mediterranean and MIND studies really show about dementia

236. dowell2022opioidguideline

     D. Dowell et al. CDC Clinical Practice Guideline for Prescribing Opioids for Pain - United States, 2022. MMWR Recomm Rep, 71(3):1-95, 2022. doi:10.15585/mmwr.rr7103a1 Evidence: Not graded (guideline)

     Verified 2026-09-28 · PMID 36327391 · DOI 10.15585/mmwr.rr7103a1

     CDC clinical practice guideline; left untiered.

     • Quiz: Drugs & substances

237. drake2013caffeine0

     C. Drake et al. Caffeine effects on sleep taken 0, 3, or 6 hours before going to bed. J Clin Sleep Med, 9(11):1195-200, 2013. doi:10.5664/jcsm.3170 Evidence: Low

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     Automated link-check got HTTP 503 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Insomnia
     • Wiki: Sleep quality
     • Wiki: Coffee, tea and energy drinks
     • What Matters: What actually moves sleep quality
     • Deep dive: The 8 things that matter most for your sleep
     • Deep dive: The 7 things to know about coffee, tea, and energy drinks
     • Deep dive: What matters most for high-quality sleep
     • Deep dive: Bryan Johnson's Ten Sleep Power Laws: what each one asks and how strong the evidence is
     • Deep dive: Top 10 insomnia remedies, ranked by the evidence
     • Quiz: Caffeine check

238. drews2020bedpartner

     H. J. Drews et al. Bed-Sharing in Couples Is Associated With Increased and Stabilized REM Sleep and Sleep-Stage Synchronization. Front Psychiatry, 11:583, 2020. doi:10.3389/fpsyt.2020.00583 Evidence: Very low

     Verified 2026-09-26 · PMID 32670111 · DOI 10.3389/fpsyt.2020.00583

     • What Matters: What actually moves sleep quality
     • Deep dive: What matters most for high-quality sleep

239. du2017abdominalobesity

     X. Du, K. Hidayat, and B. M. Shi. Abdominal obesity and gastroesophageal cancer risk: systematic review and meta-analysis of prospective studies. Biosci Rep, 37(3), 2017. doi:10.1042/BSR20160474 Evidence: Moderate

     Verified 2026-09-26 · PMID 28336766 · DOI 10.1042/BSR20160474

     • What Matters: Factors that swing esophageal cancer deaths

240. duan2015bodymass

     P. Duan et al. Body mass index and risk of lung cancer: Systematic review and dose-response meta-analysis. Sci Rep, 5:16938, 2015. doi:10.1038/srep16938 Evidence: Moderate

     Verified 2026-09-26 · PMID 26582414 · DOI 10.1038/srep16938

     • What Matters: Smoking and the rest: lung cancer death risk

241. dutheil2021effectsshort

     F. Dutheil et al. Effects of a Short Daytime Nap on the Cognitive Performance: A Systematic Review and Meta-Analysis. Int J Environ Res Public Health, 18(19):10212, 2021. doi:10.3390/ijerph181910212 Evidence: Moderate

     Verified 2026-09-27 · PMID 34639511 · DOI 10.3390/ijerph181910212

     • Wiki: Naps
     • Deep dive: Do naps make your brain younger, or are long ones a red flag?

242. dutta2013parentallongevity

     A. Dutta et al. Longer lived parents: protective associations with cancer incidence and overall mortality. J Gerontol A Biol Sci Med Sci, 68(11):1409-18, 2013. doi:10.1093/gerona/glt061 Evidence: Low

     Verified 2026-10-08 · PMID 23685624 · DOI 10.1093/gerona/glt061

     • Deep dive: What you inherit from your family, and what you don’t
     • Quiz: Family history
     • What Matters: What Affects Lifespan the Most

243. ebrahim2013alcoholsleep

     I. O. Ebrahim et al. Alcohol and sleep I: effects on normal sleep. Alcohol Clin Exp Res, 37(4):539-49, 2013. doi:10.1111/acer.12006 Evidence: Very low

     Verified 2026-09-26 · PMID 23347102 · DOI 10.1111/acer.12006

     • Wiki: Insomnia
     • Wiki: Sleep quality
     • Wiki: Alcohol
     • Deep dive: The 8 things that matter most for your sleep
     • Deep dive: The 7 things to know about alcohol
     • Deep dive: What matters most for high-quality sleep
     • Deep dive: Bryan Johnson's Ten Sleep Power Laws: what each one asks and how strong the evidence is

244. echouffotcheugui2016prediabetes

     J. B. Echouffo-Tcheugui et al. Association between prediabetes and risk of chronic kidney disease: a systematic review and meta-analysis. Diabet Med, 33(12):1615-1624, 2016. doi:10.1111/dme.13113 Evidence: Moderate

     Verified 2026-09-26 · PMID 26997583 · DOI 10.1111/dme.13113

     • What Matters: Factors that swing kidney disease deaths

245. edinger2021aasmbehavioral

     J. D. Edinger et al. Behavioral and psychological treatments for chronic insomnia disorder in adults: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med, 17(2):255-262, 2021. doi:10.5664/jcsm.8986 Evidence: Not graded (guideline)

     Verified 2026-10-08 · PMID 33164742 · DOI 10.5664/jcsm.8986

     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

246. edwards2023exercisemode

     J. J. Edwards et al. Exercise training and resting blood pressure: a large-scale pairwise and network meta-analysis of randomised controlled trials. Br J Sports Med, 57(20):1317-1326, 2023. doi:10.1136/bjsports-2022-106503 Evidence: High

     Verified 2026-09-27 · PMID 37491419 · DOI 10.1136/bjsports-2022-106503

     • Wiki: Exercise and longevity
     • Wiki: Resistance training
     • Wiki: Blood pressure
     • Wiki: Exercise (section)
     • Deep dive: Is your blood pressure quietly aging you? The 9 things that matter most

247. efsa2015caffeinesafety

     EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). Scientific Opinion on the safety of caffeine. EFSA J, 13(5):4102, 2015. doi:10.2903/j.efsa.2015.4102 Evidence: Not graded (guideline)

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     Agency scientific opinion (not indexed in PubMed; metadata from Crossref); left untiered.

     • Deep dive: The 7 things to know about coffee, tea, and energy drinks

248. ehrlich2021visionimpairment

     J. R. Ehrlich et al. Association between vision impairment and mortality: a systematic review and meta-analysis. Lancet Glob Health, 9(4):e418-e430, 2021. doi:10.1016/S2214-109X(20)30549-0 Evidence: Moderate

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     • Wiki: Hearing and vision loss
     • Deep dive: Are your ears and eyes quietly aging your brain?
     • Quiz: Hearing & vision
     • Quiz: Hearing & vision check

249. ekblombak2014nonexercise

     E. Ekblom-Bak et al. The importance of non-exercise physical activity for cardiovascular health and longevity. British Journal of Sports Medicine, 48(3):233-238, 2014. doi:10.1136/bjsports-2012-092038 Evidence: Low

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     • Deep dive: Does having a pet actually help you live longer?

250. ekelund2016activityoffsetting

     U. Ekelund et al. Does physical activity attenuate, or even eliminate, the detrimental association of sitting time with mortality? A harmonised meta-analysis of data from more than 1 million men and women. Lancet, 388(10051):1302-10, 2016. doi:10.1016/S0140-6736(16)30370-1 Evidence: High

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     • Wiki: Exercise and longevity
     • Wiki: Sedentary time
     • Wiki: Cardiovascular disease
     • Wiki: Exercise (section)
     • Wiki: Everyday movement (section)
     • What Matters: Movement: What Matters?
     • Deep dive: The 10 things that matter most for your heart
     • Deep dive: The 8 things that matter most in exercise
     • Quiz: Exercise

251. ekelund2019accelerometermeasured

     U. Ekelund et al. Dose-response associations between accelerometry measured physical activity and sedentary time and all cause mortality: systematic review and harmonised meta-analysis. BMJ, 366:l4570, 2019. doi:10.1136/bmj.l4570 Evidence: High

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Exercise and longevity
     • Wiki: Sedentary time
     • Wiki: Everyday movement (section)
     • What Matters: Movement: What Matters?

252. ekholm2020weightedblanket

     B. Ekholm, S. Spulber, and M. Adler. A randomized controlled study of weighted chain blankets for insomnia in psychiatric disorders. J Clin Sleep Med, 16(9):1567-1577, 2020. doi:10.5664/jcsm.8636 Evidence: Low

     Verified 2026-09-26 · PMID 32536366 · DOI 10.5664/jcsm.8636

     • What Matters: What actually moves sleep quality
     • Deep dive: Top 10 insomnia remedies, ranked by the evidence
     • What Matters: The healthiest habits, ranked

253. electronic2024electronicmedia

     X. Han, E. Zhou, and D. Liu. Electronic Media Use and Sleep Quality: Updated Systematic Review and Meta-Analysis. J Med Internet Res, 26:e48356, 2024. doi:10.2196/48356 Evidence: Low

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     • What Matters: What stretches, or shreds, attention

254. elserag2004diabetesliver

     H. B. El-Serag, T. Tran, and J. E. Everhart. Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma. Gastroenterology, 126(2):460-8, 2004. doi:10.1053/j.gastro.2003.10.065 Evidence: Low

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     VA cohort of 173,643 veterans with diabetes and 650,620 without, liver disease excluded at baseline; 98% men.

     • What Matters: Factors that swing liver disease deaths

255. emdin2015usualblood

     C. A. Emdin et al. Usual Blood Pressure and Risk of New-Onset Diabetes: Evidence From 4.1 Million Adults and a Meta-Analysis of Prospective Studies. J Am Coll Cardiol, 66(14):1552-1562, 2015. doi:10.1016/j.jacc.2015.07.059 Evidence: High

     Verified 2026-09-26 · PMID 26429079 · DOI 10.1016/j.jacc.2015.07.059

     • What Matters: What moves diabetes death odds

256. emergingrisk2011diabetes

     S. Rao Kondapally Seshasai et al. Diabetes mellitus, fasting glucose, and risk of cause-specific death. N Engl J Med, 364(9):829-841, 2011. doi:10.1056/NEJMoa1008862 Evidence: High

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     • Wiki: Metabolic health and type 2 diabetes
     • Deep dive: The 8 things that matter most for your metabolism
     • Deep dive: The 9 factors that decide your type 2 diabetes risk
     • Quiz: Metabolic health
     • What Matters: Habits that swing heart-disease death risk
     • What Matters: Habits that change cancer death risk
     • What Matters: What Affects Lifespan the Most
     • What Matters: The healthiest habits, ranked

257. enigma2026brainaging

     H. X. Ng et al. Brain aging in bipolar disorder using a neuroimaging and machine learning-derived metric: Findings from the ENIGMA BD Working Group. J Affect Disord, 403:121234, 2026. doi:10.1016/j.jad.2026.121234 Evidence: Very low

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     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

258. enomoto2026effectslater

     M. Enomoto et al. Effects of later dinner timing on subsequent metabolic function and nocturnal sleep in healthy young women. J Physiol Anthropol, 45(1), 2026. doi:10.1186/s40101-026-00430-0 Evidence: Low

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     • Wiki: Meal timing
     • Deep dive: Does an early last meal actually help you live longer?

259. epel2004telomereshortening

     E. S. Epel et al. Accelerated telomere shortening in response to life stress. Proc Natl Acad Sci U S A, 101(49):17312-5, 2004. doi:10.1073/pnas.0407162101 Evidence: Very low

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     • Wiki: Telomeres

260. erickson2011aerobicexercise

     K. I. Erickson et al. Exercise training increases size of hippocampus and improves memory. Proc Natl Acad Sci U S A, 108(7):3017-22, 2011. doi:10.1073/pnas.1015950108 Evidence: Low

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Exercise and longevity
     • Wiki: Dementia risk factors
     • Wiki: Cognitive aging
     • Deep dive: The 8 things to know about Alzheimer’s risk

261. erland2017melatonincontent

     L. A. Erland and P. K. Saxena. Melatonin Natural Health Products and Supplements: Presence of Serotonin and Significant Variability of Melatonin Content. J Clin Sleep Med, 13(2):275-281, 2017. doi:10.5664/jcsm.6462 Evidence: Very low

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     • Wiki: Supplements (section)
     • Wiki: Melatonin (supplement)

262. estruch2006mediterraneandiet

     R. Estruch et al. Effects of a Mediterranean-style diet on cardiovascular risk factors: a randomized trial. Ann Intern Med, 145(1):1-11, 2006. doi:10.7326/0003-4819-145-1-200607040-00004 Evidence: Low

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Inflammation and aging
     • Deep dive: The 9 things that matter most for taming inflammation

263. estruch2018primaryprevention

     R. Estruch et al. Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts. N Engl J Med, 378(25):e34, 2018. doi:10.1056/NEJMoa1800389 Evidence: Moderate

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     PREDIMED trial's 2018 corrected republication. Original URL (nejm.org, bot-blocked to automated checks) swapped for the equivalent PubMed record.

     • Wiki: Dietary patterns
     • Wiki: Cardiovascular disease
     • Wiki: Diet and nutrition (section)
     • Deep dive: The 10 things that matter most for your heart
     • Deep dive: The 8 things that matter most on your plate
     • Deep dive: Vegan, vegetarian, omnivore, carnivore: what the labels actually buy you

264. ettehad2016bloodpressure

     D. Ettehad et al. Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis. Lancet, 387(10022):957-967, 2016. doi:10.1016/S0140-6736(15)01225-8 Evidence: High

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     • Wiki: Blood pressure
     • Wiki: Heart and metabolic health (section)
     • Quiz: Heart health
     • What Matters: Habits that swing heart-disease death risk
     • What Matters: What raises — or cuts — stroke death risk

265. evening2022eveninglight

     C. Cajochen et al. Influence of evening light exposure on polysomnographically assessed night-time sleep: A systematic review with meta-analysis. Light Res Technol, 54(6):609-624, 2022. doi:10.1177/14771535221078765 Evidence: Low

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • What Matters: What stretches, or shreds, attention

266. eyting2025shinglesvaccination

     M. Eyting et al. A natural experiment on the effect of herpes zoster vaccination on dementia. Nature, 641(8062):438-446, 2025. doi:10.1038/s41586-025-08800-x Evidence: Low

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     • What Matters: What raises dementia risk most
     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • What Matters: Factors behind Alzheimer’s death risk
     • What Matters: The healthiest habits, ranked

267. fadnes2022diet

     L. T. Fadnes et al. Estimating impact of food choices on life expectancy: A modeling study. PLoS Med, 19(2):e1003889, 2022. doi:10.1371/journal.pmed.1003889 Evidence: Moderate

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     • Wiki: Dietary patterns
     • Deep dive: Vegan, vegetarian, omnivore, carnivore: what the labels actually buy you
     • Quiz: Diet
     • Quiz: Diet check
     • What Matters: What Affects Lifespan the Most
     • What Matters: The healthiest habits, ranked

268. farvid2020fiberconsumption

     M. S. Farvid et al. Fiber consumption and breast cancer incidence: a systematic review and meta-analysis of prospective studies. Cancer, 126(13):3061-75, 2020. doi:10.1002/cncr.32816 Evidence: Moderate

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     • What Matters: What changes breast cancer odds

269. fathzadeh2026dietaryfiber

     K. Fathzadeh et al. The association between dietary fiber intake and risk of lung cancer: a GRADE-assessed systematic review and dose response meta-analysis of prospective cohort studies. Nutr J, 25(1), 2026. doi:10.1186/s12937-026-01337-3 Evidence: Moderate

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     • What Matters: Smoking and the rest: lung cancer death risk

270. fedewa2017exercisetraining

     M. V. Fedewa, E. D. Hathaway, and C. L. Ward-Ritacco. Effect of exercise training on C reactive protein: a systematic review and meta-analysis of randomised and non-randomised controlled trials. Br J Sports Med, 51(8):670-676, 2017. doi:10.1136/bjsports-2016-095999 Evidence: Moderate

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Inflammation and aging
     • Deep dive: The 9 things that matter most for taming inflammation

271. fedirko2011alcoholdrinking

     V. Fedirko et al. Alcohol drinking and colorectal cancer risk: an overall and dose-response meta-analysis of published studies. Ann Oncol, 22(9):1958-1972, 2011. doi:10.1093/annonc/mdq653 Evidence: High

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     • Wiki: Colon health
     • Deep dive: The 9 things that matter most for your colon

272. felitti1998relationshipchildhood

     V. J. Felitti et al. Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The Adverse Childhood Experiences (ACE) Study. Am J Prev Med, 14(4):245-58, 1998. doi:10.1016/s0749-3797(98)00017-8 Evidence: Very low

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     • Wiki: Adverse childhood experiences
     • Deep dive: Adverse childhood experiences: what an ACE score predicts, and what still helps now

273. ference2012earlylifelong

     B. A. Ference et al. Effect of long-term exposure to lower low-density lipoprotein cholesterol beginning early in life on the risk of coronary heart disease: a Mendelian randomization analysis. J Am Coll Cardiol, 60(25):2631-9, 2012. doi:10.1016/j.jacc.2012.09.017 Evidence: High

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Cholesterol
     • Deep dive: The 10 things that matter most for your heart
     • Deep dive: The 9 things that matter most for your cholesterol

274. ference2017ldlcause

     B. A. Ference et al. Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel. Eur Heart J, 38(32):2459-2472, 2017. doi:10.1093/eurheartj/ehx144 Evidence: Not graded (guideline)

     Verified 2026-09-28 · PMID 28444290 · DOI 10.1093/eurheartj/ehx144

     European Atherosclerosis Society consensus statement; left untiered.

     • Wiki: Cardiovascular disease
     • Wiki: Cholesterol
     • Quiz: Cholesterol check

275. ference2019lifetimeldl

     B. A. Ference et al. Association of Genetic Variants Related to Combined Exposure to Lower Low-Density Lipoproteins and Lower Systolic Blood Pressure With Lifetime Risk of Cardiovascular Disease. JAMA, 322(14):1381-1391, 2019. doi:10.1001/jama.2019.14120 Evidence: Low

     Verified 2026-09-26 · PMID 31475726 · DOI 10.1001/jama.2019.14120

     • Wiki: Cardiovascular disease
     • Wiki: Blood pressure
     • Wiki: Cholesterol
     • Deep dive: The 10 things that matter most for your heart
     • Deep dive: The 9 things that matter most for your cholesterol
     • Quiz: Cholesterol check

276. ferracioli2013melatonin

     E. Ferracioli-Oda, A. Qawasmi, and M. H. Bloch. Meta-analysis: melatonin for the treatment of primary sleep disorders. PLoS One, 8(5):e63773, 2013. doi:10.1371/journal.pone.0063773 Evidence: Moderate

     Verified 2026-09-22 · PMID 23691095 · DOI 10.1371/journal.pone.0063773

     • Wiki: Insomnia
     • Wiki: Supplements (section)
     • Wiki: Melatonin (supplement)
     • What Matters: What actually moves sleep quality
     • Deep dive: What matters most for high-quality sleep
     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

277. ferrucci2018inflammagingchronic

     L. Ferrucci and E. Fabbri. Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty. Nat Rev Cardiol, 15(9):505-522, 2018. doi:10.1038/s41569-018-0064-2 Evidence: Very low

     Verified 2026-09-27 · PMID 30065258 · DOI 10.1038/s41569-018-0064-2

     • Wiki: Sarcopenia
     • Wiki: Inflammation and aging
     • Deep dive: The 9 things that matter most for taming inflammation

278. fircanis2014cigarettesmoking

     S. Fircanis et al. The relation between cigarette smoking and risk of acute myeloid leukemia: an updated meta-analysis of epidemiological studies. Am J Hematol, 89(8):E125-32, 2014. doi:10.1002/ajh.23744 Evidence: High

     Verified 2026-09-26 · PMID 24753145 · DOI 10.1002/ajh.23744

     • What Matters: What moves blood-cancer death risk

279. fischer2015secondhandsmoke

     F. Fischer and A. Kraemer. Meta-analysis of the association between second-hand smoke exposure and ischaemic heart diseases, COPD and stroke. BMC Public Health, 15:1202, 2015. doi:10.1186/s12889-015-2489-4 Evidence: High

     Verified 2026-09-26 · PMID 26627181 · DOI 10.1186/s12889-015-2489-4

     • Wiki: Smoking
     • What Matters: Factors that swing COPD deaths

280. fleg2005aerobicdecline

     J. L. Fleg et al. Accelerated longitudinal decline of aerobic capacity in healthy older adults. Circulation, 112(5):674-82, 2005. doi:10.1161/CIRCULATIONAHA.105.545459 Evidence: Low

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     • Wiki: VO2 max
     • Wiki: Cardio and aerobic fitness (section)

281. florio2020abdominalgluteofemoral

     A. A. Florio et al. Abdominal and gluteofemoral size and risk of liver cancer: The liver cancer pooling project. Int J Cancer, 147(3):675-685, 2020. doi:10.1002/ijc.32760 Evidence: High

     Verified 2026-09-26 · PMID 31677159 · DOI 10.1002/ijc.32760

     • What Matters: Habits behind liver cancer death risk

282. flossmann2004strokeheritability

     U. G. Schulz, E. Flossmann, and P. M. Rothwell. Heritability of ischemic stroke in relation to age, vascular risk factors, and subtypes of incident stroke in population-based studies. Stroke, 35(4):819-24, 2004. doi:10.1161/01.STR.0000121646.23955.0f Evidence: Low

     Verified 2026-09-26 · PMID 15001788 · DOI 10.1161/01.STR.0000121646.23955.0f

     • Family: Early stroke in close family

283. ford2025eradicationtherapy

     A. C. Ford et al. Eradication therapy to prevent gastric cancer in Helicobacter pylori-positive individuals: systematic review and meta-analysis of randomized controlled trials and observational studies. Gastroenterology, 169(2):261-76, 2025. doi:10.1053/j.gastro.2024.12.033 Evidence: High

     Verified 2026-09-30 · PMID 39824392 · DOI 10.1053/j.gastro.2024.12.033

     • Wiki: Helicobacter pylori
     • Wiki: Digestive and oral health (section)
     • Deep dive: H. pylori and stomach cancer: what the evidence shows
     • What Matters: What raises stomach cancer death risk

284. formisano2025eggs

     E. Formisano et al. Effect of egg consumption on health outcomes: An updated umbrella review of systematic reviews and meta-analysis of observational and intervention studies. Nutr Metab Cardiovasc Dis, 35(5):103849, 2025. doi:10.1016/j.numecd.2025.103849 Evidence: Low

     Verified 2026-10-01 · PMID 39934049 · DOI 10.1016/j.numecd.2025.103849

     • Wiki: Eggs

285. fox2004predictorsnewonset

     C. S. Fox et al. Predictors of new-onset kidney disease in a community-based population. JAMA, 291(7):844-50, 2004. doi:10.1001/jama.291.7.844 Evidence: Low

     Verified 2026-09-26 · PMID 14970063 · DOI 10.1001/jama.291.7.844

     Single community cohort (Framingham Offspring, n=2,585); outcome is new-onset kidney disease by eGFR, not kidney failure.

     • What Matters: Factors that swing kidney disease deaths

286. franceschi2000inflammaging

     C. Franceschi et al. Inflamm-aging. An evolutionary perspective on immunosenescence. Ann N Y Acad Sci, 908:244-54, 2000. doi:10.1111/j.1749-6632.2000.tb06651.x Evidence: Very low

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     • Wiki: Inflammation and aging

287. franceschi2014chronicinflammation

     C. Franceschi and J. Campisi. Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases. J Gerontol A Biol Sci Med Sci, 69 Suppl 1:S4-9, 2014. doi:10.1093/gerona/glu057 Evidence: Not graded (review)

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     • Wiki: Inflammation and aging
     • Deep dive: The 9 things that matter most for taming inflammation

288. franco2005bloodpressure

     O. H. Franco et al. Blood pressure in adulthood and life expectancy with cardiovascular disease in men and women: life course analysis. Hypertension, 46(2):280-6, 2005. doi:10.1161/01.HYP.0000173433.67426.9b Evidence: Low

     Verified 2026-09-26 · PMID 15983235 · DOI 10.1161/01.HYP.0000173433.67426.9b

     • Wiki: Blood pressure
     • Deep dive: The 10 things that matter most for your heart
     • Deep dive: Is your blood pressure quietly aging you? The 9 things that matter most
     • Quiz: Heart health
     • Quiz: Blood pressure check
     • What Matters: What Affects Lifespan the Most
     • What Matters: The healthiest habits, ranked

289. franke2013advancedbrainage

     K. Franke et al. Advanced BrainAGE in older adults with type 2 diabetes mellitus. Front Aging Neurosci, 5:90, 2013. doi:10.3389/fnagi.2013.00090 Evidence: Very low

     Verified 2026-09-26 · PMID 24381557 · DOI 10.3389/fnagi.2013.00090

     • Wiki: Cognitive aging
     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

290. franks2021stressrisk

     K. H. Franks et al. Association of Stress with Risk of Dementia and Mild Cognitive Impairment: A Systematic Review and Meta-Analysis. J Alzheimers Dis, 82(4):1573-1590, 2021. doi:10.3233/JAD-210094 Evidence: Low

     Verified 2026-09-26 · PMID 34366334 · DOI 10.3233/JAD-210094

     • What Matters: What raises dementia risk most
     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • What Matters: Factors behind Alzheimer’s death risk
     • What Matters: The healthiest habits, ranked

291. fraser2014agesmortality

     S. D. Fraser et al. Skin autofluorescence and all-cause mortality in stage 3 CKD. Clin J Am Soc Nephrol, 9(8):1361-8, 2014. doi:10.2215/cjn.09510913 Evidence: Low

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     • Wiki: Skin aging
     • Deep dive: What your skin is actually telling you about how long you live

292. freedman2010meatfat

     N. D. Freedman et al. Association of meat and fat intake with liver disease and hepatocellular carcinoma in the NIH-AARP cohort. J Natl Cancer Inst, 102(17):1354-65, 2010. doi:10.1093/jnci/djq301 Evidence: Low

     Verified 2026-09-26 · PMID 20729477 · DOI 10.1093/jnci/djq301

     • What Matters: Factors that swing liver disease deaths

293. freedman2011associationbetween

     N. D. Freedman et al. Association between smoking and risk of bladder cancer among men and women. JAMA, 306(7):737-45, 2011. doi:10.1001/jama.2011.1142 Evidence: Moderate

     Verified 2026-09-26 · PMID 21846855 · DOI 10.1001/jama.2011.1142

     • What Matters: What changes bladder cancer death risk

294. freedman2012coffeedrinking

     N. D. Freedman et al. Association of coffee drinking with total and cause-specific mortality. N Engl J Med, 366(20):1891-904, 2012. doi:10.1056/NEJMoa1112010 Evidence: Low

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Coffee, tea and energy drinks
     • Wiki: Diet and nutrition (section)
     • Deep dive: The 7 things worth knowing about hydration
     • Deep dive: The 7 things to know about coffee, tea, and energy drinks
     • Quiz: Diet
     • Quiz: Caffeine check

295. friberg2007diabetesmellitus

     E. Friberg et al. Diabetes mellitus and risk of endometrial cancer: a meta-analysis. Diabetologia, 50(7):1365-74, 2007. doi:10.1007/s00125-007-0681-5 Evidence: Moderate

     Verified 2026-09-26 · PMID 17476474 · DOI 10.1007/s00125-007-0681-5

     • What Matters: Habits that change uterine cancer death risk

296. friedman2024outcomessmokers

     E. B. Friedman et al. Outcomes for smokers who develop melanoma: a systematic review and meta-analysis. EClinicalMedicine, 77:102872, 2024. doi:10.1016/j.eclinm.2024.102872 Evidence: High

     Verified 2026-09-26 · PMID 39763510 · DOI 10.1016/j.eclinm.2024.102872

     • What Matters: Sun and the rest: melanoma death risk

297. friedmann2023petownership

     E. Friedmann et al. Pet ownership and maintenance of cognitive function in community-residing older adults: evidence from the Baltimore Longitudinal Study of Aging (BLSA). Sci Rep, 13(1):14738, 2023. doi:10.1038/s41598-023-41813-y Evidence: Low

     Verified 2026-09-26 · PMID 37679499 · DOI 10.1038/s41598-023-41813-y

     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

298. fryar2026overweightobesityhestat

     Fryar CD, Afful J, Saif NT. Prevalence of overweight, obesity, and severe obesity among adults age 20 and older: United States, 1960–1962 through August 2021–August 2023 (NCHS Health E-Stats 111). National Center for Health Statistics, 2026. Evidence: Not graded (statistics)

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     Cited for the unadjusted August 2021–August 2023 adult mix: overweight 32.1%, obesity 40.3%, severe obesity 9.4%.

     • What Matters: Your estimated chance of each cause (method)

299. gallo2013depressioncare

     J. J. Gallo et al. Long term effect of depression care management on mortality in older adults: follow-up of cluster randomized clinical trial in primary care. BMJ, 346:f2570, 2013. doi:10.1136/bmj.f2570 Evidence: Low

     Verified 2026-09-27 · PMID 23738992 · DOI 10.1136/bmj.f2570

     • Wiki: Mental health conditions and lifespan
     • Deep dive: The mental health conditions that cost the most years, ranked
     • Deep dive: What depression does to a lifespan, treated and untreated
     • Quiz: Mental wellbeing

300. gandini2005riskfactors

     S. Gandini et al. Meta-analysis of risk factors for cutaneous melanoma: II. Sun exposure. Eur J Cancer, 41(1):45-60, 2005. doi:10.1016/j.ejca.2004.10.016 Evidence: Moderate

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     • What Matters: Sun and the rest: melanoma death risk

301. gandini2005riskfactors2

     S. Gandini et al. Meta-analysis of risk factors for cutaneous melanoma: III. Family history, actinic damage and phenotypic factors. Eur J Cancer, 41(14):2040-59, 2005. doi:10.1016/j.ejca.2005.03.034 Evidence: High

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     • What Matters: Sun and the rest: melanoma death risk

302. garciacasares2020glucosecognition

     C. R. García et al. Effect of glucose and sucrose on cognition in healthy humans: a systematic review and meta-analysis of interventional studies. Nutr Rev, 79(2):171-187, 2020. doi:10.1093/nutrit/nuaa036 Evidence: Low

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • What Matters: What stretches, or shreds, attention

303. garciahermoso2018muscularstrength

     A. García-Hermoso et al. Muscular Strength as a Predictor of All-Cause Mortality in an Apparently Healthy Population: A Systematic Review and Meta-Analysis of Data From Approximately 2 Million Men and Women. Arch Phys Med Rehabil, 99(10):2100-2113.e5, 2018. doi:10.1016/j.apmr.2018.01.008 Evidence: High

     Verified 2026-09-26 · PMID 29425700 · DOI 10.1016/j.apmr.2018.01.008

     • Wiki: Muscle mass
     • Wiki: Grip strength
     • Wiki: Strength and muscle (section)
     • What Matters: Movement: What Matters?

304. gardiner2023caffeine

     C. Gardiner et al. The effect of caffeine on subsequent sleep: A systematic review and meta-analysis. Sleep Med Rev, 69:101764, 2023. doi:10.1016/j.smrv.2023.101764 Evidence: Moderate

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     • Wiki: Insomnia
     • Wiki: Sleep quality
     • Wiki: Coffee, tea and energy drinks
     • What Matters: What actually moves sleep quality
     • Deep dive: What matters most for high-quality sleep
     • Deep dive: Bryan Johnson's Ten Sleep Power Laws: what each one asks and how strong the evidence is
     • Deep dive: Top 10 insomnia remedies, ranked by the evidence
     • Quiz: Bryan Johnson's Ten Sleep Power Laws
     • What Matters: The healthiest habits, ranked

305. gardiner2024effectalcohol

     C. Gardiner et al. The effect of alcohol on subsequent sleep in healthy adults: A systematic review and meta-analysis. Sleep Med Rev, 80:102030, 2024. doi:10.1016/j.smrv.2024.102030 Evidence: Moderate

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     • Wiki: Sleep quality
     • Wiki: Alcohol
     • What Matters: What actually moves sleep quality
     • Deep dive: What matters most for high-quality sleep
     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

306. garrett2024acuteexercise

     J. Garrett et al. A systematic review and Bayesian meta-analysis provide evidence for an effect of acute physical activity on cognition in young adults. Commun Psychol, 2(1):82, 2024. doi:10.1038/s44271-024-00124-2 Evidence: Moderate

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     • What Matters: What stretches, or shreds, attention

307. gaudet2013activesmoking

     M. M. Gaudet et al. Active smoking and breast cancer risk: original cohort data and meta-analysis. J Natl Cancer Inst, 105(8):515-25, 2013. doi:10.1093/jnci/djt023 Evidence: Moderate

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     • What Matters: What changes breast cancer odds

308. gbd2018nosafe

     GBD 2016 Alcohol Collaborators. Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet, 392(10152):1015-1035, 2018. doi:10.1016/s0140-6736(18)31310-2 Evidence: Moderate

     Verified 2026-09-27 · PMID 30146330 · DOI 10.1016/s0140-6736(18)31310-2

     • Wiki: Alcohol
     • Wiki: Alcohol and tobacco (section)
     • Deep dive: The 7 things to know about alcohol

309. gbd2019healtheffects

     GBD 2017 Diet Collaborators. Health effects of dietary risks in 195 countries, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet, 393(10184):1958-1972, 2019. doi:10.1016/s0140-6736(19)30041-8 Evidence: Moderate

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     • Wiki: Dietary patterns
     • Wiki: Dietary fiber
     • Wiki: Diet and nutrition (section)
     • Deep dive: The 8 things that matter most on your plate

310. gbd2021visioncauses

     GBD 2019 Blindness and Vision Impairment Collaborators and Vision Loss Expert Group of the Global Burden of Disease Study. Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for the Global Burden of Disease Study. Lancet Glob Health, 9(2):e144-e160, 2021. doi:10.1016/S2214-109X(20)30489-7 Evidence: High

     Verified 2026-09-29 · PMID 33275949 · DOI 10.1016/S2214-109X(20)30489-7

     • Wiki: Hearing and vision loss

311. gbd2021visionprevalence

     GBD 2019 Blindness and Vision Impairment Collaborators and Vision Loss Expert Group of the Global Burden of Disease Study. Trends in prevalence of blindness and distance and near vision impairment over 30 years: an analysis for the Global Burden of Disease Study. Lancet Glob Health, 9(2):e130-e143, 2021. doi:10.1016/S2214-109X(20)30425-3 Evidence: High

     Verified 2026-09-29 · PMID 33275950 · DOI 10.1016/S2214-109X(20)30425-3

     • Wiki: Hearing and vision loss

312. gbd2022mentaldisorders

     GBD 2019 Mental Disorders Collaborators. Global, regional, and national burden of 12 mental disorders in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet Psychiatry, 9(2):137-150, 2022. doi:10.1016/S2215-0366(21)00395-3 Evidence: Moderate

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     • Wiki: Mental health conditions and lifespan
     • Wiki: Mental health and relationships (section)

313. ge2019insomniamortality

     L. Ge et al. Insomnia and risk of mortality from all-cause, cardiovascular disease, and cancer: Systematic review and meta-analysis of prospective cohort studies. Sleep Med Rev, 48:101215, 2019. doi:10.1016/j.smrv.2019.101215 Evidence: Moderate

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     • Wiki: Insomnia

314. genderson2013genesremainder

     M. R. Genderson et al. Genetic and environmental influences on sleep quality in middle-aged men: a twin study. J Sleep Res, 22(5):519-26, 2013. doi:10.1111/jsr.12048 Evidence: Very low

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     • Wiki: Sleep quality
     • What Matters: What actually moves sleep quality
     • Deep dive: What matters most for high-quality sleep

315. genin2011apoealzheimer

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     • Wiki: Dementia risk factors
     • Wiki: Family history and genetics
     • What Matters: What raises dementia risk most
     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • Deep dive: The 8 things to know about Alzheimer’s risk
     • What Matters: Factors behind Alzheimer’s death risk

316. gibson2014risknon

     T. M. Gibson et al. Risk of non-Hodgkin lymphoma subtypes in HIV-infected people during the HAART era: a population-based study. AIDS, 28(15):2313-8, 2014. doi:10.1097/QAD.0000000000000428 Evidence: Low

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     • What Matters: What moves blood-cancer death risk

317. giem1993incidencedementia

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     • Deep dive: Plants and your brain: what the vegetarian, Mediterranean and MIND studies really show about dementia

318. gillespie2012fallsinterventions

     L. D. Gillespie et al. Interventions for preventing falls in older people living in the community. Cochrane Database Syst Rev, 2012(9):CD007146, 2012. doi:10.1002/14651858.CD007146.pub3 Evidence: High

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     • Wiki: Fall prevention

319. giosue2022fattyfish

     A. Giosuè et al. Relations between the Consumption of Fatty or Lean Fish and Risk of Cardiovascular Disease and All-Cause Mortality: A Systematic Review and Meta-Analysis. Adv Nutr, 13(5):1554-1565, 2022. doi:10.1093/advances/nmac006 Evidence: High

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     • Wiki: Fish

320. gleeson2011antiinflammatory

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     • Wiki: Exercise and longevity
     • Wiki: Inflammation and aging
     • Wiki: Longevity theories (section)
     • Deep dive: The 9 things that matter most for taming inflammation

321. global2016bmimortality

     Global BMI Mortality Collaboration et al. Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents. Lancet, 388(10046):776-86, 2016. doi:10.1016/S0140-6736(16)30175-1 Evidence: High

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     • Wiki: Body weight
     • Deep dive: The 8 things that matter most for your metabolism
     • Deep dive: How much is the extra weight actually costing you?
     • Quiz: Body weight
     • Quiz: Weight check

322. global2024smokingcessation

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     • Wiki: Cardiovascular disease
     • Deep dive: The 10 things that matter most for your heart

323. glycaemic2022glycaemicload

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     • What Matters: What stretches, or shreds, attention

324. gonzalezgomez2026strengthtraining

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     • Wiki: Resistance training
     • Wiki: Cognitive aging
     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

325. goyal2014meditationprograms

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     • Wiki: Stress and anxiety
     • Deep dive: The 8 things that matter most for staying calm

326. green2011nambourrct

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Skin aging
     • Deep dive: What your skin is actually telling you about how long you live
     • Quiz: Skin health
     • What Matters: Sun and the rest: melanoma death risk

327. greider1985telomerase

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     • Wiki: Telomeres

328. griffith1999tloop

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     • Wiki: Telomeres

329. grntved2011televisionviewing

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     • Wiki: Sedentary time
     • What Matters: What moves diabetes death odds

330. grossman2005gunstorage

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     Metadata confirmed against the Europe PMC MEDLINE record for this PMID (NCBI E-utilities unavailable 2026-09-26).

     • What Matters: Factors linked to suicide deaths

331. gu2015mediterraneandiet

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     • Wiki: Cognitive aging
     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

332. gu2015totalcause

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     • Wiki: Sleep duration and mortality
     • What Matters: What sleep does to how long you live
     • Deep dive: How sleep affects how long you live

333. gunter2017coffeedrinking

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     • Wiki: Coffee, tea and energy drinks
     • Deep dive: The 7 things to know about coffee, tea, and energy drinks

334. guyuron2009facialaging

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     • Wiki: Skin aging

335. hachem2025rolesauna

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     Verified 2026-09-27 · PMID 41426898 · DOI 10.7759/cureus.98162

     • Wiki: Heat exposure
     • Deep dive: Does the sauna actually make you live longer?

336. haentjens2010hipfracture

     P. Haentjens et al. Meta-analysis: excess mortality after hip fracture among older women and men. Ann Intern Med, 152(6):380-90, 2010. doi:10.7326/0003-4819-152-6-201003160-00008 Evidence: Moderate

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     • Wiki: Fall prevention
     • Wiki: Balance, mobility and function (section)

337. haggerjohnson2014reactiontime

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     • Deep dive: Body Check: five at-home tests linked to how long you live

338. haghayegh2019warmbath

     S. Haghayegh et al. Before-bedtime passive body heating by warm shower or bath to improve sleep: A systematic review and meta-analysis. Sleep Med Rev, 46:124-135, 2019. doi:10.1016/j.smrv.2019.04.008 Evidence: Moderate

     Verified 2026-09-26 · PMID 31102877 · DOI 10.1016/j.smrv.2019.04.008

     • Wiki: Sleep physiology
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     • What Matters: What actually moves sleep quality
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     • Deep dive: Bryan Johnson's Ten Sleep Power Laws: what each one asks and how strong the evidence is
     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

339. hajna2023associationsbetween

     S. Hajna, V. Nafilyan, and S. Cummins. Associations between residential greenspace exposure and mortality in 4 645 581 adults living in London, UK: a longitudinal study. Lancet Planet Health, 7(6):e459-e468, 2023. doi:10.1016/S2542-5196(23)00057-8 Evidence: Low

     Verified 2026-09-26 · PMID 37286243 · DOI 10.1016/S2542-5196(23)00057-8

     • Wiki: Green space
     • Wiki: Environment and safety (section)
     • Deep dive: Does living somewhere green actually help you live longer?

340. hall2019ultraprocessed

     K. D. Hall et al. Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain: An Inpatient Randomized Controlled Trial of Ad Libitum Food Intake. Cell Metab, 30(1):67-77.e3, 2019. doi:10.1016/j.cmet.2019.05.008 Evidence: Low

     Verified 2026-09-26 · PMID 31105044 · DOI 10.1016/j.cmet.2019.05.008

     • Wiki: Metabolic health and type 2 diabetes
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     • Deep dive: The 8 things that matter most for your metabolism
     • Deep dive: How much is the extra weight actually costing you?
     • Quiz: Diet check

341. hamajima2002alcoholtobacco

     N. Hamajima et al. Alcohol, tobacco and breast cancer--collaborative reanalysis of individual data from 53 epidemiological studies, including 58,515 women with breast cancer and 95,067 women without the disease. Br J Cancer, 87(11):1234-45, 2002. doi:10.1038/sj.bjc.6600596 Evidence: High

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     • What Matters: What changes breast cancer odds

342. han2021brainaging

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     Verified 2026-09-26 · PMID 32424236 · DOI 10.1038/s41380-020-0754-0

     • Wiki: Cognitive aging
     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

343. han2021contributingfactors

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     • Deep dive: How to lower your cognitive age: every habit with a number in years

344. hanski2012environmentalbiodiversity

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Green space
     • Deep dive: Does living somewhere green actually help you live longer?

345. hansrivijit2021bidirectionalassociation

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     • What Matters: Factors that swing kidney disease deaths

346. harley1990telomeresshorten

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     • Wiki: Telomeres

347. hart2007antithrombotictherapy

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     • What Matters: What raises — or cuts — stroke death risk

348. hartescu2015activityinsomnia

     I. Hartescu, K. Morgan, and C. D. Stevinson. Increased physical activity improves sleep and mood outcomes in inactive people with insomnia: a randomized controlled trial. J Sleep Res, 24(5):526-34, 2015. doi:10.1111/jsr.12297 Evidence: Low

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     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

349. hartley2014taichi

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     • Wiki: Yoga and tai chi

350. harvardnaharvardadult

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     Cited generically as the study itself, not a single dated paper: the study's own page describing the Grant and Glueck cohorts (title read from the live page 2026-09-28). No single publication year applies.

     • Deep dive: The 8 things that matter most for connection and purpose

351. harvey2002imagerydistraction

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     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

352. harvey2023daytimeinsomnia

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     • Wiki: Insomnia
     • Wiki: Sleep duration and mortality
     • What Matters: What sleep does to how long you live
     • Deep dive: How sleep affects how long you live

353. hasan2022exercisesleepnma

     F. Hasan et al. Comparative efficacy of exercise regimens on sleep quality in older adults: A systematic review and network meta-analysis. Sleep Med Rev, 65:101673, 2022. doi:10.1016/j.smrv.2022.101673 Evidence: Moderate

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     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

354. hausler2019napfrequency

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     • Wiki: Naps

355. hayflick1961serialcultivation

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     • Wiki: Telomeres

356. he1999passivesmoking

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     • Wiki: Smoking
     • What Matters: Habits that swing heart-disease death risk

357. he2006fruitvegetable

     F. J. He, C. A. Nowson, and G. A. MacGregor. Fruit and vegetable consumption and stroke: meta-analysis of cohort studies. Lancet, 367(9507):320-6, 2006. doi:10.1016/S0140-6736(06)68069-0 Evidence: High

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     • What Matters: What raises — or cuts — stroke death risk

358. he2020phonebefore

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     • What Matters: What actually moves sleep quality
     • Deep dive: What matters most for high-quality sleep
     • What Matters: The healthiest habits, ranked

359. hedstrom2021insomniasuicide

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     Metadata confirmed against the Europe PMC MEDLINE record for this PMID (NCBI E-utilities unavailable 2026-09-26). Fifth author kept exactly as indexed ("LY Trolle").

     • What Matters: Factors linked to suicide deaths

360. heishman2010acutenicotine

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     • What Matters: What stretches, or shreds, attention

361. helicobacter2001gastriccancer

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     • Wiki: Helicobacter pylori
     • Deep dive: H. pylori and stomach cancer: what the evidence shows
     • What Matters: What raises stomach cancer death risk

362. hepsomali2020gaba

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     Front Neurosci is a continuous-publication journal with no issue number.

     • Wiki: Supplements (section)
     • Wiki: GABA (supplement)

363. herskind1996heritability

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     • Wiki: Family history and genetics
     • Wiki: Longevity theories (section)
     • Deep dive: What you inherit from your family, and what you don’t
     • Quiz: Family history
     • What Matters: What Affects Lifespan the Most

364. herxheimer2002melatoninjetlag

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     • Wiki: Supplements (section)
     • Wiki: Melatonin (supplement)
     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

365. hhs2020smokingcessationsgr

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     Verified 2026-09-26

     Cited for the quit ratio: in 2018, 61.7% of adults who had ever smoked had quit.

     • What Matters: Your estimated chance of each cause (method)

366. hidese2019ltheanine

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     PR #555 audit: the original PMID (31336816) resolved to an unrelated Charcot-Marie-Tooth review; corrected to 31623400.

     • Wiki: L-theanine (supplement)

367. hill2014purposelife

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Stress and anxiety
     • Wiki: Social connection
     • Deep dive: The 8 things that matter most for connection and purpose
     • Deep dive: The 8 things that matter most for staying calm
     • Quiz: Mental wellbeing

368. hjetland2025screenuse

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     • Deep dive: Bryan Johnson's Ten Sleep Power Laws: what each one asks and how strong the evidence is
     • Deep dive: Top 10 insomnia remedies, ranked by the evidence
     • Quiz: Bryan Johnson's Ten Sleep Power Laws

369. hjorthj2017yearslife

     C. Hjorthøj et al. Years of potential life lost and life expectancy in schizophrenia: a systematic review and meta-analysis. Lancet Psychiatry, 4(4):295-301, 2017. doi:10.1016/s2215-0366(17)30078-0 Evidence: High

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     • Wiki: Mental health conditions and lifespan
     • Deep dive: The mental health conditions that cost the most years, ranked
     • Quiz: Mental wellbeing

370. ho2015chronicindwelling

     C. H. Ho et al. Chronic Indwelling Urinary Catheter Increase the Risk of Bladder Cancer, Even in Patients Without Spinal Cord Injury. Medicine (Baltimore), 94(43):e1736, 2015. doi:10.1097/MD.0000000000001736 Evidence: Low

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     • What Matters: What changes bladder cancer death risk

371. holland2020dietaryflavonols

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     • Deep dive: Plants and your brain: what the vegetarian, Mediterranean and MIND studies really show about dementia

372. holtlunstad2010social

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     • Wiki: Hearing and vision loss
     • Wiki: Social connection
     • Wiki: Adverse childhood experiences
     • Wiki: Mental health and relationships (section)
     • Deep dive: The 8 things that matter most for connection and purpose
     • Deep dive: The sports that add the most years, ranked
     • Deep dive: The mental health conditions that cost the most years, ranked
     • Deep dive: Are your ears and eyes quietly aging your brain?
     • Deep dive: Adverse childhood experiences: what an ACE score predicts, and what still helps now
     • Quiz: Social life
     • What Matters: What Affects Lifespan the Most
     • What Matters: The healthiest habits, ranked

373. holtlunstad2015lonelinesssocial

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Social connection
     • Wiki: Pet ownership
     • Wiki: Mental health and relationships (section)
     • Deep dive: The 8 things that matter most for connection and purpose
     • Deep dive: Does having a pet actually help you live longer?

374. honaandrogeneticalopecia

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     StatPearls entries are periodically updated with no single stated publication year; automated re-check bot-blocked (reCAPTCHA), URL carried over from pre-existing curated content.

     • Deep dive: The 9 things balding is actually telling you about your health

375. hooi2017globalprevalence

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     • Wiki: Helicobacter pylori
     • Deep dive: H. pylori and stomach cancer: what the evidence shows

376. hooper2020reducingsaturated

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     • Wiki: Cholesterol
     • Deep dive: The 9 things that matter most for your cholesterol

377. hou2018obstructivesleep

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     • Wiki: Blood pressure
     • What Matters: Levers on hypertensive disease deaths

378. hsu2005elevatedblood

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     • What Matters: Factors that swing kidney disease deaths

379. hsu2006bodymass

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     • What Matters: Factors that swing kidney disease deaths

380. hu2018smokingcessation

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Smoking
     • Wiki: Metabolic health and type 2 diabetes
     • Deep dive: Smoking takes about ten years. Here is what quitting gives back

381. hu2023grains

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     • Wiki: Whole grains
     • Wiki: Refined grains
     • What Matters: Foods ranked for longevity

382. hu2026dairy

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     • Wiki: Yogurt

383. hu2026mealtiming

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     • Wiki: Meal timing
     • Wiki: Diet and nutrition (section)
     • Deep dive: Does an early last meal actually help you live longer?
     • Deep dive: Bryan Johnson's Ten Sleep Power Laws: what each one asks and how strong the evidence is

384. huai2013physicalactivity

     P. Huai et al. Physical activity and risk of hypertension: a meta-analysis of prospective cohort studies. Hypertension, 62(6):1021-6, 2013. doi:10.1161/HYPERTENSIONAHA.113.01965 Evidence: High

     Verified 2026-09-26 · PMID 24082054 · DOI 10.1161/HYPERTENSIONAHA.113.01965

     • What Matters: Levers on hypertensive disease deaths

385. huang2003cagaseropositivity

     J. Q. Huang et al. Meta-analysis of the relationship between cagA seropositivity and gastric cancer. Gastroenterology, 125(6):1636-44, 2003. doi:10.1053/j.gastro.2003.08.033 Evidence: Moderate

     Verified 2026-10-04 · PMID 14724815 · DOI 10.1053/j.gastro.2003.08.033

     • Wiki: Helicobacter pylori
     • Deep dive: H. pylori and stomach cancer: what the evidence shows

386. huang2012diabetesmellitus

     W. Huang et al. Risk of esophageal cancer in diabetes mellitus: a meta-analysis of observational studies. Cancer Causes Control, 23(2):263-72, 2012. doi:10.1007/s10552-011-9874-9 Evidence: Moderate

     Verified 2026-09-26 · PMID 22094992 · DOI 10.1007/s10552-011-9874-9

     • What Matters: Factors that swing esophageal cancer deaths

387. huang2017aspirinnon

     X. Z. Huang et al. Aspirin and non-steroidal anti-inflammatory drugs use reduce gastric cancer risk: A dose-response meta-analysis. Oncotarget, 8(3):4781-4795, 2017. doi:10.18632/oncotarget.13591 Evidence: High

     Verified 2026-09-26 · PMID 27902474 · DOI 10.18632/oncotarget.13591

     • What Matters: What raises stomach cancer death risk

388. huang2023sugar

     Y. Huang et al. Dietary sugar consumption and health: umbrella review. BMJ, 381:e071609, 2023. doi:10.1136/bmj-2022-071609 Evidence: Moderate

     Verified 2026-10-01 · PMID 37019448 · DOI 10.1136/bmj-2022-071609

     • Wiki: Sugary drinks

389. huang2023sugars

     C. Huang et al. Total sugar, added sugar, fructose, and sucrose intake and all-cause, cardiovascular, and cancer mortality: A systematic review and dose-response meta-analysis of prospective cohort studies. Nutrition, 111:112032, 2023. doi:10.1016/j.nut.2023.112032 Evidence: Moderate

     Verified 2026-10-01 · PMID 37182401 · DOI 10.1016/j.nut.2023.112032

     • Wiki: Sweets and added sugar

390. hughes2013sunscreenprevention

     M. C. Hughes et al. Sunscreen and prevention of skin aging: a randomized trial. Ann Intern Med, 158(11):781-790, 2013. doi:10.7326/0003-4819-158-11-201306040-00002 Evidence: Moderate

     Verified 2026-09-29 · PMID 23732711 · DOI 10.7326/0003-4819-158-11-201306040-00002

     • Wiki: Skin aging
     • Wiki: Skin and hair (section)

391. hughes2017effectmultiple

     K. Hughes et al. The effect of multiple adverse childhood experiences on health: a systematic review and meta-analysis. Lancet Public Health, 2(8):e356-e366, 2017. doi:10.1016/S2468-2667(17)30118-4 Evidence: Low

     Verified 2026-09-26 · PMID 29253477 · DOI 10.1016/S2468-2667(17)30118-4

     • Wiki: Adverse childhood experiences
     • Wiki: Mental health and relationships (section)
     • Deep dive: Adverse childhood experiences: what an ACE score predicts, and what still helps now

392. hughes2020bloodpressure

     D. Hughes et al. Association of Blood Pressure Lowering With Incident Dementia or Cognitive Impairment: A Systematic Review and Meta-analysis. JAMA, 323(19):1934-1944, 2020. doi:10.1001/jama.2020.4249 Evidence: High

     Verified 2026-09-26 · PMID 32427305 · DOI 10.1001/jama.2020.4249

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • What Matters: What raises dementia risk most
     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • What Matters: Factors behind Alzheimer’s death risk
     • What Matters: The healthiest habits, ranked

393. hughesnatelogeneffluvium

     E. C. Hughes, H. A. Syed, and D. Saleh. Telogen Effluvium. StatPearls Publishing. Evidence: Not graded (reference page)

     Verified 2026-09-27

     StatPearls entries are periodically updated with no single stated publication year; automated re-check bot-blocked (reCAPTCHA), URL carried over from pre-existing curated content.

     • Wiki: Hair loss
     • Deep dive: The 9 things balding is actually telling you about your health

394. hugosson201916year

     J. Hugosson et al. A 16-yr Follow-up of the European Randomized study of Screening for Prostate Cancer. Eur Urol, 76(1):43-51, 2019. doi:10.1016/j.eururo.2019.02.009 Evidence: Moderate

     Verified 2026-09-26 · PMID 30824296 · DOI 10.1016/j.eururo.2019.02.009

     • What Matters: Levers on prostate cancer death risk

395. humphrey2008periodontaldisease

     L. L. Humphrey et al. Periodontal disease and coronary heart disease incidence: a systematic review and meta-analysis. J Gen Intern Med, 23(12):2079-86, 2008. doi:10.1007/s11606-008-0787-6 Evidence: High

     Verified 2026-09-26 · PMID 18807098 · DOI 10.1007/s11606-008-0787-6

     • Wiki: Oral health
     • Wiki: Inflammation and aging
     • Wiki: Digestive and oral health (section)
     • Deep dive: The 9 things that matter most for taming inflammation
     • Deep dive: Does oral care actually affect how long you live?

396. hussain2022infraredsauna

     J. N. Hussain et al. Infrared sauna as exercise-mimetic? Physiological responses to infrared sauna vs exercise in healthy women: A randomized controlled crossover trial. Complement Ther Med, 64:102798, 2022. doi:10.1016/j.ctim.2021.102798 Evidence: Low

     Verified 2026-09-26 · PMID 34954348 · DOI 10.1016/j.ctim.2021.102798

     • Wiki: Heat exposure
     • Deep dive: Does the sauna actually make you live longer?

397. huxley2005typeii

     R. Huxley et al. Type-II diabetes and pancreatic cancer: a meta-analysis of 36 studies. Br J Cancer, 92(11):2076-83, 2005. doi:10.1038/sj.bjc.6602619 Evidence: Moderate

     Verified 2026-09-26 · PMID 15886696 · DOI 10.1038/sj.bjc.6602619

     • What Matters: What moves pancreatic cancer death risk

398. huynh2024incidencesurvival

     M. J. Huynh et al. Incidence and survival of secondary malignancies after external beam radiotherapy for prostate cancer in the SEER database. Can Urol Assoc J, 18(4):121-128, 2024. doi:10.5489/cuaj.8508 Evidence: Low

     Verified 2026-09-26 · PMID 38381941 · DOI 10.5489/cuaj.8508

     • What Matters: What changes bladder cancer death risk

399. iao2022lateeating

     S. I. Iao et al. Associations between bedtime eating or drinking, sleep duration and wake after sleep onset: findings from the American time use survey. Br J Nutr, 127(12):1888-1897, 2022. doi:10.1017/S0007114521003597 Evidence: Very low

     Verified 2026-09-26 · PMID 34511160 · DOI 10.1017/S0007114521003597

     • What Matters: What actually moves sleep quality
     • Deep dive: What matters most for high-quality sleep

400. iarc2012solaruv

     IARC Monograph 100D. Radiation (IARC Monographs Volume 100D). IARC Monograph 100D, 2012. Evidence: Not graded (guideline)

     Verified 2026-09-27

     • Wiki: Skin aging
     • Deep dive: What your skin is actually telling you about how long you live
     • Quiz: Skin health

401. iarc2024globalcancer

     International Agency for Research on Cancer. Cancer Today. Global Cancer Observatory, International Agency for Research on Cancer, 2024. Evidence: Not graded (statistics)

     Verified 2026-09-27

     • Deep dive: What your skin is actually telling you about how long you live
     • Quiz: Skin health

402. ilgen2016opioidsuicide

     M. A. Ilgen et al. Opioid dose and risk of suicide. Pain, 157(5):1079-1084, 2016. doi:10.1097/j.pain.0000000000000484 Evidence: Low

     Verified 2026-09-26 · PMID 26761386 · DOI 10.1097/j.pain.0000000000000484

     Metadata confirmed against the Europe PMC MEDLINE record for this PMID (NCBI E-utilities unavailable 2026-09-26).

     • What Matters: Factors linked to suicide deaths

403. imamura2015ssbt2d

     F. Imamura et al. Consumption of sugar sweetened beverages, artificially sweetened beverages, and fruit juice and incidence of type 2 diabetes: systematic review, meta-analysis, and estimation of population attributable fraction. BMJ, 351:h3576, 2015. doi:10.1136/bmj.h3576 Evidence: Moderate

     Verified 2026-10-05 · PMID 26199070 · DOI 10.1136/bmj.h3576

     • Deep dive: Diet soda vs regular soda vs water: what the evidence shows

404. independent2012breastscreening

     Independent UK Panel on Breast Cancer Screening. The benefits and harms of breast cancer screening: an independent review. Lancet, 380(9855):1778-86, 2012. doi:10.1016/S0140-6736(12)61611-0 Evidence: Moderate

     Verified 2026-09-28 · PMID 23117178 · DOI 10.1016/S0140-6736(12)61611-0

     • Quiz: Preventive care

405. inouechoi2013sugarsweetened

     M. Inoue-Choi et al. Sugar-sweetened beverage intake and the risk of type I and type II endometrial cancer among postmenopausal women. Cancer Epidemiol Biomarkers Prev, 22(12):2384-94, 2013. doi:10.1158/1055-9965.EPI-13-0636 Evidence: Low

     Verified 2026-09-26 · PMID 24273064 · DOI 10.1158/1055-9965.EPI-13-0636

     • What Matters: Habits that change uterine cancer death risk

406. inouechoi2017lowintensity

     M. Inoue-Choi et al. Association of Long-term, Low-Intensity Smoking With All-Cause and Cause-Specific Mortality in the National Institutes of Health-AARP Diet and Health Study. JAMA Intern Med, 177(1):87-95, 2017. doi:10.1001/jamainternmed.2016.7511 Evidence: Low

     Verified 2026-09-27 · PMID 27918784 · DOI 10.1001/jamainternmed.2016.7511

     • Wiki: Smoking
     • Wiki: Alcohol and tobacco (section)
     • Deep dive: Smoking takes about ten years. Here is what quitting gives back
     • Quiz: Smoking
     • Quiz: Smoking check
     • What Matters: Smoking and the rest: lung cancer death risk

407. inouechoi2022blacktea

     M. Inoue-Choi et al. Tea Consumption and All-Cause and Cause-Specific Mortality in the UK Biobank : A Prospective Cohort Study. Ann Intern Med, 175(9):1201-1211, 2022. doi:10.7326/M22-0041 Evidence: Low

     Verified 2026-09-26 · PMID 36037472 · DOI 10.7326/M22-0041

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Coffee, tea and energy drinks
     • Deep dive: The 7 things to know about coffee, tea, and energy drinks
     • Quiz: Diet
     • Quiz: Caffeine check

408. institute2005dietaryreference

     Institute of Medicine. Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate. Institute of Medicine, 2005. Evidence: Not graded (guideline)

     Verified 2026-09-27

     • Wiki: Hydration
     • Deep dive: The 7 things worth knowing about hydration

409. insurancenaadvanceddriver

     Insurance Institute for Highway Safety. Advanced driver assistance. Insurance Institute for Highway Safety (IIHS). Evidence: Not graded (reference page)

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     Continuously-updated agency topic page, no single publication year stated.

     • Wiki: Road safety
     • Deep dive: The 9 things that matter most for surviving the road

410. interact2013diabetesfamilyhistory

     InterAct Consortium et al. The link between family history and risk of type 2 diabetes is not explained by anthropometric, lifestyle or genetic risk factors: the EPIC-InterAct study. Diabetologia, 56(1):60-9, 2013. doi:10.1007/s00125-012-2715-x Evidence: Moderate

     Verified 2026-09-26 · PMID 23052052 · DOI 10.1007/s00125-012-2715-x

     • Wiki: Metabolic health and type 2 diabetes
     • Wiki: Family history and genetics
     • Deep dive: What you inherit from your family, and what you don’t
     • Family: Type 2 diabetes in parents/siblings
     • What Matters: What Affects Lifespan the Most

411. irwin2016sleepdisturbance

     M. R. Irwin, R. Olmstead, and J. E. Carroll. Sleep Disturbance, Sleep Duration, and Inflammation: A Systematic Review and Meta-Analysis of Cohort Studies and Experimental Sleep Deprivation. Biol Psychiatry, 80(1):40-52, 2016. doi:10.1016/j.biopsych.2015.05.014 Evidence: Moderate

     Verified 2026-09-26 · PMID 26140821 · DOI 10.1016/j.biopsych.2015.05.014

     • Wiki: Sleep physiology
     • Wiki: Insomnia
     • Wiki: Inflammation and aging
     • Wiki: Longevity theories (section)
     • Deep dive: The 9 things that matter most for taming inflammation

412. irwin2020caffeineafter

     C. Irwin et al. Effects of acute caffeine consumption following sleep loss on cognitive, physical, occupational and driving performance: A systematic review and meta-analysis. Neurosci Biobehav Rev, 108:877-888, 2020. doi:10.1016/j.neubiorev.2019.12.008 Evidence: Moderate

     Verified 2026-09-26 · PMID 31837359 · DOI 10.1016/j.neubiorev.2019.12.008

     • What Matters: What stretches, or shreds, attention

413. ishii2022occasionslaughter

     Y. Wang et al. Occasions for laughter and dementia risk: Findings from a six-year cohort study. Geriatr Gerontol Int, 22(5):392-398, 2022. doi:10.1111/ggi.14371 Evidence: Low

     Verified 2026-09-26 · PMID 35289045 · DOI 10.1111/ggi.14371

     Regex-only miss (year was already in the original label, inside a parenthetical); no URL change needed.

     • Deep dive: How to lower your cognitive age: every habit with a number in years

414. islami2011alcoholdrinking

     F. Islami et al. Alcohol drinking and esophageal squamous cell carcinoma with focus on light-drinkers and never-smokers: a systematic review and meta-analysis. Int J Cancer, 129(10):2473-84, 2011. doi:10.1002/ijc.25885 Evidence: Moderate

     Verified 2026-09-26 · PMID 21190191 · DOI 10.1002/ijc.25885

     • What Matters: Factors that swing esophageal cancer deaths

415. islami2014tobaccouse

     F. Islami et al. A systematic review and meta-analysis of tobacco use and prostate cancer mortality and incidence in prospective cohort studies. Eur Urol, 66(6):1054-64, 2014. doi:10.1016/j.eururo.2014.08.059 Evidence: High

     Verified 2026-09-26 · PMID 25242554 · DOI 10.1016/j.eururo.2014.08.059

     • What Matters: Levers on prostate cancer death risk

416. isomarkku2022physicalactivity

     P. Iso-Markku et al. Physical activity as a protective factor for dementia and Alzheimer's disease: systematic review, meta-analysis and quality assessment of cohort and case-control studies. Br J Sports Med, 56(12):701-709, 2022. doi:10.1136/bjsports-2021-104981 Evidence: High

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • What Matters: What raises dementia risk most
     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • What Matters: Factors behind Alzheimer’s death risk
     • What Matters: The healthiest habits, ranked

417. ivey2017flavonoidfoods

     K. L. Ivey et al. Association of flavonoid-rich foods and flavonoids with risk of all-cause mortality. Br J Nutr, 117(10):1470-1477, 2017. doi:10.1017/S0007114517001325 Evidence: Low

     Verified 2026-10-01 · PMID 28606222 · DOI 10.1017/S0007114517001325

     • Wiki: Berries
     • Wiki: Citrus fruit

418. j2026plantbased

     J. Shen et al. Association between plant-based diets and incident dementia: results from prospective cohort studies and a meta-analysis. J Prev Alzheimers Dis, 13(2):100457, 2026. doi:10.1016/j.tjpad.2025.100457 Evidence: Moderate

     Verified 2026-09-26 · PMID 41564649 · DOI 10.1016/j.tjpad.2025.100457

     • Deep dive: Plants and your brain: what the vegetarian, Mediterranean and MIND studies really show about dementia

419. jacobs2014intrinsicextrinsic

     L. C. Jacobs et al. Intrinsic and extrinsic risk factors for sagging eyelids. JAMA Dermatol, 150(8):836-43, 2014. doi:10.1001/jamadermatol.2014.27 Evidence: Very low

     Verified 2026-09-27 · PMID 24869959 · DOI 10.1001/jamadermatol.2014.27

     • Wiki: Skin aging
     • Wiki: Skin and hair (section)
     • Deep dive: What your eyebags are actually telling you about your health

420. james2016exposuregreenness

     P. James et al. Exposure to Greenness and Mortality in a Nationwide Prospective Cohort Study of Women. Environ Health Perspect, 124(9):1344-52, 2016. doi:10.1289/ehp.1510363 Evidence: Low

     Verified 2026-09-26 · PMID 27074702 · DOI 10.1289/ehp.1510363

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Green space
     • Deep dive: Does living somewhere green actually help you live longer?

421. janssonfrojmark2008anxietymood

     M. Jansson-Fröjmark and K. Lindblom. A bidirectional relationship between anxiety and depression, and insomnia? A prospective study in the general population. J Psychosom Res, 64(4):443-9, 2008. doi:10.1016/j.jpsychores.2007.10.016 Evidence: Low

     Verified 2026-09-26 · PMID 18374745 · DOI 10.1016/j.jpsychores.2007.10.016

     • Wiki: Sleep quality
     • What Matters: What actually moves sleep quality
     • Deep dive: What matters most for high-quality sleep

422. jayakody2026supermovers

     O. Jayakody et al. Cognitive Aging and Brain Health: A Comparison of Super Movers vs Nonsuper Movers. Neurology, 107(1):e214776, 2026. doi:10.1212/WNL.0000000000214776 Evidence: Moderate

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • What Matters: What moves your cognitive age
     • What Matters: The healthiest habits, ranked

423. jayedi2020centralfatness

     A. Jayedi et al. Central fatness and risk of all cause mortality: systematic review and dose-response meta-analysis of 72 prospective cohort studies. BMJ, 370:m3324, 2020. doi:10.1136/bmj.m3324 Evidence: Moderate

     Verified 2026-09-30 · PMID 32967840 · DOI 10.1136/bmj.m3324

     • Deep dive: Body Check: five at-home tests linked to how long you live

424. jayedi2020fishumbrella

     A. Jayedi and S. Shab-Bidar. Fish Consumption and the Risk of Chronic Disease: An Umbrella Review of Meta-Analyses of Prospective Cohort Studies. Adv Nutr, 11(5):1123-1133, 2020. doi:10.1093/advances/nmaa029 Evidence: High

     Verified 2026-10-01 · PMID 32207773 · DOI 10.1093/advances/nmaa029

     • Wiki: Fish
     • What Matters: Foods ranked for longevity

425. jayedi2022bodyfat

     A. Jayedi et al. Anthropometric and adiposity indicators and risk of type 2 diabetes: systematic review and dose-response meta-analysis of cohort studies. BMJ, 376:e067516, 2022. doi:10.1136/bmj-2021-067516 Evidence: High

     Verified 2026-09-26 · PMID 35042741 · DOI 10.1136/bmj-2021-067516

     • Wiki: Metabolic health and type 2 diabetes
     • What Matters: What moves diabetes death odds

426. je2012coffeeconsumption

     Y. Je and E. Giovannucci. Coffee consumption and risk of endometrial cancer: findings from a large up-to-date meta-analysis. Int J Cancer, 131(7):1700-10, 2012. doi:10.1002/ijc.27408 Evidence: High

     Verified 2026-09-26 · PMID 22190017 · DOI 10.1002/ijc.27408

     • What Matters: Habits that change uterine cancer death risk

427. jenkins2003portfoliodiet

     D. J. Jenkins et al. Effects of a dietary portfolio of cholesterol-lowering foods vs lovastatin on serum lipids and C-reactive protein. JAMA, 290(4):502-10, 2003. doi:10.1001/jama.290.4.502 Evidence: Low

     Verified 2026-09-26 · PMID 12876093 · DOI 10.1001/jama.290.4.502

     • Wiki: Cholesterol
     • Deep dive: The 9 things that matter most for your cholesterol

428. jenkins2026farinfraredINCOMPLETE METADATA

     E. J. Jenkins et al. Far-infrared sauna exposure at 65°C elevates core temperature. Exp Physiol, EP094028, 2026. doi:10.1113/ep094028 Evidence: Very low

     Verified 2026-09-27 · PMID 42533687 · DOI 10.1113/ep094028

     Published online ahead of print; PubMed lists an article number but no volume or issue yet (checked 2026-09-27).

     • Wiki: Heat exposure
     • Deep dive: Does the sauna actually make you live longer?

429. jensen2013restingheart

     M. T. Jensen et al. Elevated resting heart rate, physical fitness and all-cause mortality: a 16-year follow-up in the Copenhagen Male Study. Heart, 99(12):882-7, 2013. doi:10.1136/heartjnl-2012-303375 Evidence: Low

     Verified 2026-09-28 · PMID 23595657 · DOI 10.1136/heartjnl-2012-303375

     • Quiz: Heart health

430. jespersen2022musicinsomnia

     K. V. Jespersen et al. Listening to music for insomnia in adults. Cochrane Database Syst Rev, 8(8):CD010459, 2022. doi:10.1002/14651858.CD010459.pub3 Evidence: Moderate

     Verified 2026-09-26 · PMID 36000763 · DOI 10.1002/14651858.CD010459.pub3

     • What Matters: What actually moves sleep quality
     • Deep dive: Top 10 insomnia remedies, ranked by the evidence
     • What Matters: The healthiest habits, ranked

431. jha2013smoking

     P. Jha et al. 21st-century hazards of smoking and benefits of cessation in the United States. N Engl J Med, 368(4):341-50, 2013. doi:10.1056/NEJMsa1211128 Evidence: Low

     Verified 2026-09-26 · PMID 23343063 · DOI 10.1056/NEJMsa1211128

     • Wiki: Smoking
     • Wiki: Cardiovascular disease
     • Wiki: Alcohol and tobacco (section)
     • Deep dive: The 10 things that matter most for your heart
     • Deep dive: Smoking takes about ten years. Here is what quitting gives back
     • Deep dive: Adverse childhood experiences: what an ACE score predicts, and what still helps now
     • Quiz: Smoking
     • Quiz: Smoking check
     • What Matters: What Affects Lifespan the Most
     • What Matters: The healthiest habits, ranked

432. jiang2026ecigarette

     Y. Jiang, Y. Wang, and M. Yang. Association between current e-cigarette use and chronic obstructive pulmonary disease: a meta-analysis focusing on exclusive e-cigarette users. Front Public Health, 14:1802572, 2026. doi:10.3389/fpubh.2026.1802572 Evidence: Low

     Verified 2026-09-26 · PMID 42100525 · DOI 10.3389/fpubh.2026.1802572

     • Wiki: Smoking
     • What Matters: Factors that swing COPD deaths

433. jimenez2022residentialgreen

     M. P. Jimenez et al. Residential Green Space and Cognitive Function in a Large Cohort of Middle-Aged Women. JAMA Netw Open, 5(4):e229306, 2022. doi:10.1001/jamanetworkopen.2022.9306 Evidence: Very low

     Verified 2026-09-27 · PMID 35476063 · DOI 10.1001/jamanetworkopen.2022.9306

     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years

434. jin2005familialaggregation

     Y. T. Jin et al. Familial aggregation of lung cancer in a high incidence area in China. Br J Cancer, 92(7):1321-5, 2005. doi:10.1038/sj.bjc.6602465 Evidence: Low

     Verified 2026-09-26 · PMID 15756270 · DOI 10.1038/sj.bjc.6602465

     • What Matters: Smoking and the rest: lung cancer death risk

435. jin2013alcoholdrinking

     M. Jin et al. Alcohol drinking and all cancer mortality: a meta-analysis. Ann Oncol, 24(3):807-16, 2013. doi:10.1093/annonc/mds508 Evidence: High

     Verified 2026-09-26 · PMID 23104725 · DOI 10.1093/annonc/mds508

     • What Matters: Habits that change cancer death risk

436. johansson2010midlifepsychological

     L. Johansson et al. Midlife psychological stress and risk of dementia: a 35-year longitudinal population study. Brain, 133(Pt 8):2217-24, 2010. doi:10.1093/brain/awq116 Evidence: Low

     Verified 2026-09-26 · PMID 20488887 · DOI 10.1093/brain/awq116

     • What Matters: What raises dementia risk most
     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • What Matters: Factors behind Alzheimer’s death risk
     • What Matters: The healthiest habits, ranked

437. johns2001systematicfamilial

     L. E. Johns and R. S. Houlston. A systematic review and meta-analysis of familial colorectal cancer risk. Am J Gastroenterol, 96(10):2992-3003, 2001. doi:10.1111/j.1572-0241.2001.04677.x Evidence: High

     Verified 2026-09-26 · PMID 11693338 · DOI 10.1111/j.1572-0241.2001.04677.x

     • Wiki: Family history and genetics
     • What Matters: What changes bowel cancer death risk

438. johnson2024sleeppowerlaws

     B. Johnson. The Ten Sleep Power Laws. Don't Die protocol, 2024. Evidence: Not graded (news release)

     Verified 2026-10-03

     The sleep section of Bryan Johnson's Don't Die protocol, read in the Don't Die app (Protocol tab, updated 2024-11-25); quoted from in-app screenshots supplied by Jeff on 2026-10-03. The URL is the protocol's public landing page, which points to the app. The protocol's own claims are attributed to it, not checked by YapSpan.

     • Deep dive: Bryan Johnson's Ten Sleep Power Laws: what each one asks and how strong the evidence is
     • Quiz: Bryan Johnson's Ten Sleep Power Laws

439. johnson2025powerlaws

     B. Johnson. The Three Power Laws of Health. Blueprint, 2025. Evidence: Not graded (news release)

     Verified 2026-10-02

     Bryan Johnson's (Don't Die) own post putting sleep first among his power laws of health. Published 2025-04-04.

     • Deep dive: Bryan Johnson's Ten Sleep Power Laws: what each one asks and how strong the evidence is
     • Quiz: Bryan Johnson's Ten Sleep Power Laws

440. jongen2014alcoholcalibration

     S. Jongen et al. Alcohol calibration of tests measuring skills related to car driving. Psychopharmacology, 231(12):2435-47, 2014. doi:10.1007/s00213-013-3408-y Evidence: Low

     Verified 2026-09-26 · PMID 24408210 · DOI 10.1007/s00213-013-3408-y

     • What Matters: What stretches, or shreds, attention

441. jordan2017breastfeedingendometrial

     S. J. Jordan et al. Breastfeeding and endometrial cancer risk: an analysis from the Epidemiology of Endometrial Cancer Consortium. Obstet Gynecol, 129(6):1059-67, 2017. doi:10.1097/AOG.0000000000002057 Evidence: Moderate

     Verified 2026-09-30 · PMID 28486362 · DOI 10.1097/AOG.0000000000002057

     • What Matters: Habits that change uterine cancer death risk

442. jung2023mushroom

     H. Jung et al. Edible mushroom intake and risk of all-cause and cause-specific mortality: results from the Korean Genome and Epidemiology Study (KoGES) Cohort. Food Funct, 14(19):8829-8837, 2023. doi:10.1039/d3fo00996c Evidence: Low

     Verified 2026-10-01 · PMID 37682230 · DOI 10.1039/d3fo00996c

     • Wiki: Mushrooms

443. kaluza2017fruitvegetable

     J. Kaluza et al. Fruit and vegetable consumption and risk of COPD: a prospective cohort study of men. Thorax, 72(6):500-509, 2017. doi:10.1136/thoraxjnl-2015-207851 Evidence: Low

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     • What Matters: Factors that swing COPD deaths

444. kamstrup2009lipoproteina

     P. R. Kamstrup et al. Genetically elevated lipoprotein(a) and increased risk of myocardial infarction. JAMA, 301(22):2331-9, 2009. doi:10.1001/jama.2009.801 Evidence: Low

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     • Wiki: Cholesterol
     • Quiz: Cholesterol check

445. kang2022associationbetweenINCOMPLETE METADATA

     J. Kang et al. Association between obesity, brain atrophy and accelerated brain aging and their genetic mechanisms. medRxiv, 2022. doi:10.1101/2022.12.30.22284052 Evidence: Very low

     Verified 2026-09-27 · DOI 10.1101/2022.12.30.22284052

     medRxiv preprint (not peer reviewed); no journal volume or pages exist.

     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

446. kaplan2022greenmediterranean

     A. Kaplan et al. The effect of a high-polyphenol Mediterranean diet (Green-MED) combined with physical activity on age-related brain atrophy: the Dietary Intervention Randomized Controlled Trial Polyphenols Unprocessed Study (DIRECT PLUS). Am J Clin Nutr, 115(5):1270-1281, 2022. doi:10.1093/ajcn/nqac001 Evidence: Low

     Verified 2026-09-26 · PMID 35021194 · DOI 10.1093/ajcn/nqac001

     • Wiki: Dementia risk factors
     • Deep dive: Plants and your brain: what the vegetarian, Mediterranean and MIND studies really show about dementia

447. kaptoge2010creactive

     Emerging Risk Factors Collaboration et al. C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis. Lancet, 375(9709):132-40, 2010. doi:10.1016/S0140-6736(09)61717-7 Evidence: High

     Verified 2026-09-26 · PMID 20031199 · DOI 10.1016/S0140-6736(09)61717-7

     • Wiki: Inflammation and aging
     • Deep dive: The 9 things that matter most for taming inflammation

448. karim2021agingfaster

     H. T. Karim et al. Aging faster: worry and rumination in late life are associated with greater brain age. Neurobiol Aging, 101:13-21, 2021. doi:10.1016/j.neurobiolaging.2021.01.009 Evidence: Very low

     Verified 2026-09-27 · PMID 33561786 · DOI 10.1016/j.neurobiolaging.2021.01.009

     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

449. karimi2015sleepapnea

     M. Karimi et al. Sleep apnea-related risk of motor vehicle accidents is reduced by continuous positive airway pressure: Swedish Traffic Accident Registry data. Sleep, 38(3):341-9, 2015. doi:10.5665/sleep.4486 Evidence: Low

     Verified 2026-09-26 · PMID 25325460 · DOI 10.5665/sleep.4486

     • What Matters: Factors that swing accidental deaths

450. katalinic2012doesskin

     A. Katalinic et al. Does skin cancer screening save lives?: an observational study comparing trends in melanoma mortality in regions with and without screening. Cancer, 118(21):5395-402, 2012. doi:10.1002/cncr.27566 Evidence: Low

     Verified 2026-09-26 · PMID 22517033 · DOI 10.1002/cncr.27566

     • What Matters: Sun and the rest: melanoma death risk

451. katzmarzyk2014standingmortality

     P. T. Katzmarzyk. Standing and mortality in a prospective cohort of Canadian adults. Med Sci Sports Exerc, 46(5):940-6, 2014. doi:10.1249/MSS.0000000000000198 Evidence: Low

     Verified 2026-09-26 · PMID 24152707 · DOI 10.1249/MSS.0000000000000198

     • Wiki: Sedentary time
     • What Matters: Movement: What Matters?

452. kaufman1998finasteridemen

     K. D. Kaufman et al. Finasteride in the treatment of men with androgenetic alopecia. Finasteride Male Pattern Hair Loss Study Group. J Am Acad Dermatol, 39(4 Pt 1):578-89, 1998. doi:10.1016/s0190-9622(98)70007-6 Evidence: Moderate

     Verified 2026-09-26 · PMID 9777765 · DOI 10.1016/s0190-9622(98)70007-6

     • Wiki: Hair loss
     • Deep dive: The 9 things balding is actually telling you about your health

453. kaur2022pepper

     M. Kaur et al. Association of pepper intake with all-cause and specific cause mortality - A systematic review and meta-analysis. Am J Prev Cardiol, 9:100301, 2022. doi:10.1016/j.ajpc.2021.100301 Evidence: Moderate

     Verified 2026-10-01 · PMID 34977833 · DOI 10.1016/j.ajpc.2021.100301

     • Wiki: Chili peppers

454. kawai2015glycinescn

     N. Kawai et al. The sleep-promoting and hypothermic effects of glycine are mediated by NMDA receptors in the suprachiasmatic nucleus. Neuropsychopharmacology, 40(6):1405-1416, 2015. doi:10.1038/npp.2014.326 Evidence: Very low

     Verified 2026-09-28 · PMID 25533534 · DOI 10.1038/npp.2014.326

     • Wiki: Glycine (supplement)

455. kazemi2023fructose

     A. Kazemi et al. The relationship between major food sources of fructose and cardiovascular disease, cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of cohort studies. Crit Rev Food Sci Nutr, 63(20):4274-4287, 2023. doi:10.1080/10408398.2021.2000361 Evidence: High

     Verified 2026-10-01 · PMID 34847334 · DOI 10.1080/10408398.2021.2000361

     • Wiki: Sweets and added sugar

456. ke2024oliveoil

     Y. Ke et al. Olive oil intake and cardiovascular disease, cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective cohort studies. Food Funct, 15(9):4668-4681, 2024. doi:10.1039/d3fo05246j Evidence: High

     Verified 2026-10-01 · PMID 38568797 · DOI 10.1039/d3fo05246j

     • Wiki: Olive oil
     • What Matters: Foods ranked for longevity

457. keller2012stressperception

     A. Keller et al. Does the perception that stress affects health matter? The association with health and mortality. Health Psychol, 31(5):677-84, 2012. doi:10.1037/a0026743 Evidence: Low

     Verified 2026-09-26 · PMID 22201278 · DOI 10.1037/a0026743

     • Wiki: Stress and anxiety
     • Wiki: Social connection
     • Deep dive: The 8 things that matter most for connection and purpose

458. kellyirving2013adversechildhood

     M. Kelly-Irving et al. Adverse childhood experiences and premature all-cause mortality. Eur J Epidemiol, 28(9):721-34, 2013. doi:10.1007/s10654-013-9832-9 Evidence: Low

     Verified 2026-09-26 · PMID 23887883 · DOI 10.1007/s10654-013-9832-9

     • Wiki: Adverse childhood experiences
     • Deep dive: Adverse childhood experiences: what an ACE score predicts, and what still helps now

459. kennedy2016coffeeconsumption

     O. J. Kennedy et al. Systematic review with meta-analysis: coffee consumption and the risk of cirrhosis. Aliment Pharmacol Ther, 43(5):562-74, 2016. doi:10.1111/apt.13523 Evidence: Moderate

     Verified 2026-09-26 · PMID 26806124 · DOI 10.1111/apt.13523

     • What Matters: Factors that swing liver disease deaths

460. keum2014calciumintake

     N. Keum et al. Calcium intake and colorectal cancer risk: dose-response meta-analysis of prospective observational studies. Int J Cancer, 135(8):1940-8, 2014. doi:10.1002/ijc.28840 Evidence: High

     Verified 2026-09-26 · PMID 24623471 · DOI 10.1002/ijc.28840

     • What Matters: What changes bowel cancer death risk

461. khalade2010exposurebenzene

     A. Khalade et al. Exposure to benzene at work and the risk of leukemia: a systematic review and meta-analysis. Environ Health, 9:31, 2010. doi:10.1186/1476-069X-9-31 Evidence: Moderate

     Verified 2026-09-26 · PMID 20584305 · DOI 10.1186/1476-069X-9-31

     • What Matters: What moves blood-cancer death risk

462. khera2016favorablelifestyle

     A. V. Khera et al. Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease. N Engl J Med, 375(24):2349-2358, 2016. doi:10.1056/NEJMoa1605086 Evidence: Moderate

     Verified 2026-09-26 · PMID 27959714 · DOI 10.1056/NEJMoa1605086

     • Wiki: Family history and genetics
     • Deep dive: What you inherit from your family, and what you don’t

463. kicinski2011epidemiologicalreappraisal

     M. Kiciński, J. Vangronsveld, and T. S. Nawrot. An epidemiological reappraisal of the familial aggregation of prostate cancer: a meta-analysis. PLoS One, 6(10):e27130, 2011. doi:10.1371/journal.pone.0027130 Evidence: High

     Verified 2026-09-26 · PMID 22073129 · DOI 10.1371/journal.pone.0027130

     • What Matters: Levers on prostate cancer death risk

464. kim1994telomerasecancer

     N. W. Kim et al. Specific association of human telomerase activity with immortal cells and cancer. Science, 266(5193):2011-5, 1994. doi:10.1126/science.7605428 Evidence: Very low

     Verified 2026-09-28 · PMID 7605428 · DOI 10.1126/science.7605428

     • Wiki: Telomeres

465. kim2019coffee

     Y. Kim, Y. Je, and E. Giovannucci. Coffee consumption and all-cause and cause-specific mortality: a meta-analysis by potential modifiers. Eur J Epidemiol, 34(8):731-752, 2019. doi:10.1007/s10654-019-00524-3 Evidence: High

     Verified 2026-10-01 · PMID 31055709 · DOI 10.1007/s10654-019-00524-3

     • Wiki: Coffee

466. kim2023underweightstatus

     C. S. Kim et al. Underweight status and development of end-stage kidney disease: A nationwide population-based study. J Cachexia Sarcopenia Muscle, 14(5):2184-2195, 2023. doi:10.1002/jcsm.13297 Evidence: Low

     Verified 2026-09-26 · PMID 37503821 · DOI 10.1002/jcsm.13297

     Korean national cohort using Asian BMI cut-offs; the abstract prints a figure only for BMI under 17.

     • What Matters: Factors that swing kidney disease deaths

467. kim2024tea

     Y. Kim and Y. Je. Tea consumption and risk of all-cause, cardiovascular disease, and cancer mortality: a meta-analysis of thirty-eight prospective cohort data sets. Epidemiol Health, 46:e2024056, 2024. doi:10.4178/epih.e2024056 Evidence: Moderate

     Verified 2026-10-01 · PMID 38938012 · DOI 10.4178/epih.e2024056

     • Wiki: Tea
     • What Matters: Foods ranked for longevity

468. kim2025shiftwork

     Y. Kim et al. Association between shift work and brain age gap: a neuroimaging study using MRI-based brain age prediction algorithms. Front Aging Neurosci, 17:1650497, 2025. doi:10.3389/fnagi.2025.1650497 Evidence: Very low

     Verified 2026-09-26 · PMID 40951919 · DOI 10.3389/fnagi.2025.1650497

     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years

469. kirkegard2017chronicpancreatitis

     J. Kirkegård, F. V. Mortensen, and D. Cronin-Fenton. Chronic Pancreatitis and Pancreatic Cancer Risk: A Systematic Review and Meta-analysis. Am J Gastroenterol, 112(9):1366-1372, 2017. doi:10.1038/ajg.2017.218 Evidence: High

     Verified 2026-09-26 · PMID 28762376 · DOI 10.1038/ajg.2017.218

     • What Matters: What moves pancreatic cancer death risk

470. kivimaki2018stress

     M. Kivimäki and A. Steptoe. Effects of stress on the development and progression of cardiovascular disease. Nat Rev Cardiol, 15(4):215-229, 2018. doi:10.1038/nrcardio.2017.189 Evidence: Not graded (review)

     Verified 2026-09-26 · PMID 29213140 · DOI 10.1038/nrcardio.2017.189

     • Wiki: Stress and anxiety
     • Wiki: Adverse childhood experiences
     • Wiki: Inflammation and aging
     • Deep dive: The 8 things that matter most for staying calm
     • Deep dive: The 9 things that matter most for taming inflammation
     • Quiz: Stress
     • Quiz: Calm check
     • What Matters: What Affects Lifespan the Most
     • What Matters: The healthiest habits, ranked

471. klein2004prospectiverisk

     A. P. Klein et al. Prospective risk of pancreatic cancer in familial pancreatic cancer kindreds. Cancer Res, 64(7):2634-8, 2004. doi:10.1158/0008-5472.can-03-3823 Evidence: Low

     Verified 2026-09-26 · PMID 15059921 · DOI 10.1158/0008-5472.can-03-3823

     • What Matters: What moves pancreatic cancer death risk

472. klein2011vitamine

     E. A. Klein et al. Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA, 306(14):1549-56, 2011. doi:10.1001/jama.2011.1437 Evidence: Moderate

     Verified 2026-09-26 · PMID 21990298 · DOI 10.1001/jama.2011.1437

     • What Matters: Levers on prostate cancer death risk

473. knott2015alcoholconsumption

     C. Knott, S. Bell, and A. Britton. Alcohol Consumption and the Risk of Type 2 Diabetes: A Systematic Review and Dose-Response Meta-analysis of More Than 1.9 Million Individuals From 38 Observational Studies. Diabetes Care, 38(9):1804-12, 2015. doi:10.2337/dc15-0710 Evidence: Moderate

     Verified 2026-09-26 · PMID 26294775 · DOI 10.2337/dc15-0710

     • Wiki: Alcohol
     • What Matters: What moves diabetes death odds

474. knowler2002dpplifestyle

     W. C. Knowler et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med, 346(6):393-403, 2002. doi:10.1056/NEJMoa012512 Evidence: Moderate

     Verified 2026-09-26 · PMID 11832527 · DOI 10.1056/NEJMoa012512

     • Wiki: Exercise and longevity
     • Wiki: Metabolic health and type 2 diabetes
     • Wiki: Body weight
     • Wiki: Family history and genetics
     • Deep dive: The 8 things that matter most for your metabolism
     • Deep dive: The 9 factors that decide your type 2 diabetes risk
     • Deep dive: What you inherit from your family, and what you don’t
     • Deep dive: How much is the extra weight actually costing you?

475. knutson2018chronotypemortality

     K. L. Knutson and M. von Schantz. Associations between chronotype, morbidity and mortality in the UK Biobank cohort. Chronobiol Int, 35(8):1045-1053, 2018. doi:10.1080/07420528.2018.1454458 Evidence: Low

     Verified 2026-09-26 · PMID 29642757 · DOI 10.1080/07420528.2018.1454458

     • Wiki: Sleep duration and mortality
     • What Matters: What sleep does to how long you live
     • Deep dive: How sleep affects how long you live

476. kodama2009cardiorespiratoryfitness

     S. Kodama et al. Cardiorespiratory fitness as a quantitative predictor of all-cause mortality and cardiovascular events in healthy men and women: a meta-analysis. JAMA, 301(19):2024-35, 2009. doi:10.1001/jama.2009.681 Evidence: High

     Verified 2026-09-26 · PMID 19454641 · DOI 10.1001/jama.2009.681

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Exercise and longevity
     • Wiki: VO2 max
     • Wiki: High-intensity interval training
     • Wiki: Exercise (section)
     • Wiki: Cardio and aerobic fitness (section)
     • What Matters: Movement: What Matters?

477. koelega1995alcoholvigilance

     H. S. Koelega. Alcohol and vigilance performance: a review. Psychopharmacology, 118(3):233-49, 1995. doi:10.1007/BF02245951 Evidence: Very low

     Verified 2026-09-26 · PMID 7617815 · DOI 10.1007/BF02245951

     • What Matters: What stretches, or shreds, attention

478. koh2024sleepduration

     J. H. Koh et al. The association of sleep duration with the risk of chronic kidney disease: a systematic review and meta-analysis. Clin Kidney J, 17(8):sfae177, 2024. doi:10.1093/ckj/sfae177 Evidence: High

     Verified 2026-09-26 · PMID 39114497 · DOI 10.1093/ckj/sfae177

     • What Matters: Factors that swing kidney disease deaths

479. kohara2018habitualhot

     K. Kohara et al. Habitual hot water bathing protects cardiovascular function in middle-aged to elderly Japanese subjects. Sci Rep, 8(1):8687, 2018. doi:10.1038/s41598-018-26908-1 Evidence: Very low

     Verified 2026-09-27 · PMID 29930309 · DOI 10.1038/s41598-018-26908-1

     • Wiki: Heat exposure
     • Deep dive: Are hot tubs good for your health and longevity?

480. kokkinos2022fitnessmortality

     P. Kokkinos et al. Cardiorespiratory Fitness and Mortality Risk Across the Spectra of Age, Race, and Sex. J Am Coll Cardiol, 80(6):598-609, 2022. doi:10.1016/j.jacc.2022.05.031 Evidence: Low

     Verified 2026-09-26 · PMID 35926933 · DOI 10.1016/j.jacc.2022.05.031

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Exercise and longevity
     • Wiki: VO2 max
     • Wiki: Cardiovascular disease
     • Wiki: Cardio and aerobic fitness (section)
     • Deep dive: The 10 things that matter most for your heart
     • Deep dive: The 8 things that matter most in exercise

481. kondrataviciene2022apneapsqi

     L. Kondratavičienė et al. Short-Term Continuous Positive Air Pressure Treatment: Effects on Quality of Life and Sleep in Patients with Obstructive Sleep Apnea. Medicina (Kaunas), 58(3), 2022. doi:10.3390/medicina58030350 Evidence: Very low

     Verified 2026-09-26 · PMID 35334526 · DOI 10.3390/medicina58030350

     • What Matters: What actually moves sleep quality
     • Deep dive: What matters most for high-quality sleep
     • What Matters: The healthiest habits, ranked

482. kornum2008diabetespneumonia

     J. B. Kornum et al. Diabetes, glycemic control, and risk of hospitalization with pneumonia: a population-based case-control study. Diabetes Care, 31(8):1541-5, 2008. doi:10.2337/dc08-0138 Evidence: Low

     Verified 2026-09-26 · PMID 18487479 · DOI 10.2337/dc08-0138

     • What Matters: Factors that swing flu and pneumonia deaths

483. kramer2019dogownership

     C. K. Kramer, S. Mehmood, and R. S. Suen. Dog Ownership and Survival: A Systematic Review and Meta-Analysis. Circ Cardiovasc Qual Outcomes, 12(10):e005554, 2019. doi:10.1161/CIRCOUTCOMES.119.005554 Evidence: Moderate

     Verified 2026-09-26 · PMID 31592726 · DOI 10.1161/CIRCOUTCOMES.119.005554

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Pet ownership
     • Wiki: Mental health and relationships (section)
     • What Matters: Movement: What Matters?
     • Deep dive: Does having a pet actually help you live longer?
     • What Matters: What Affects Lifespan the Most

484. kratzer2025prostatecancer

     T. B. Kratzer et al. Prostate cancer statistics, 2025. CA Cancer J Clin, 75(6):485-497, 2025. doi:10.3322/caac.70028 Evidence: Not graded (statistics)

     Verified 2026-09-26 · PMID 40892160 · DOI 10.3322/caac.70028

     • What Matters: Levers on prostate cancer death risk

485. kraus2002strrideexercise

     W. E. Kraus et al. Effects of the amount and intensity of exercise on plasma lipoproteins. N Engl J Med, 347(19):1483-92, 2002. doi:10.1056/NEJMoa020194 Evidence: Low

     Verified 2026-09-26 · PMID 12421890 · DOI 10.1056/NEJMoa020194

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Cholesterol
     • Deep dive: The 9 things that matter most for your cholesterol

486. kredlow2015effectsphysical

     M. A. Kredlow et al. The effects of physical activity on sleep: a meta-analytic review. J Behav Med, 38(3):427-49, 2015. doi:10.1007/s10865-015-9617-6 Evidence: Moderate

     Verified 2026-09-26 · PMID 25596964 · DOI 10.1007/s10865-015-9617-6

     • Wiki: Sleep quality
     • Deep dive: What matters most for high-quality sleep

487. krogsboll2019healthchecks

     L. T. Krogsbøll, K. J. Jørgensen, and P. C. Gøtzsche. General health checks in adults for reducing morbidity and mortality from disease. Cochrane Database Syst Rev, 1(1):CD009009, 2019. doi:10.1002/14651858.CD009009.pub3 Evidence: High

     Verified 2026-09-28 · PMID 30699470 · DOI 10.1002/14651858.CD009009.pub3

     • Quiz: Preventive care

488. kronenberg2022lpconsensus

     F. Kronenberg et al. Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement. Eur Heart J, 43(39):3925-3946, 2022. doi:10.1093/eurheartj/ehac361 Evidence: Not graded (guideline)

     Verified 2026-09-26 · PMID 36036785 · DOI 10.1093/eurheartj/ehac361

     • Wiki: Cholesterol
     • Deep dive: The 9 things that matter most for your cholesterol

489. krustrup2018recreationalfootball

     P. Krustrup and B. R. Krustrup. Football is medicine: it is time for patients to play!. Br J Sports Med, 52(22):1412-1414, 2018. doi:10.1136/bjsports-2018-099377 Evidence: Not graded (review)

     Verified 2026-09-27 · PMID 29886433 · DOI 10.1136/bjsports-2018-099377

     Part of BJSM vol 52 issue 22's 2018 'Football is Medicine' special issue (confirmed via a sibling Krustrup paper in the same issue, PMID 29886433); the exact PMID for page 1426 specifically was not confirmed in this session — bjsm.bmj.com returns a bot-block (403) to automated checks. Automated link-check got HTTP 429 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Deep dive: The sports that add the most years, ranked

490. kuiper2015socialrelationships

     J. S. Kuiper et al. Social relationships and risk of dementia: A systematic review and meta-analysis of longitudinal cohort studies. Ageing Res Rev, 22:39-57, 2015. doi:10.1016/j.arr.2015.04.006 Evidence: High

     Verified 2026-09-27 · PMID 25956016 · DOI 10.1016/j.arr.2015.04.006

     • Wiki: Dementia risk factors
     • Wiki: Hearing and vision loss
     • Wiki: Social connection
     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • Deep dive: Are your ears and eyes quietly aging your brain?

491. kumar2026socialjetlag

     N. Kumar and S. Krishnamurthy. Social jet lag is associated with incident cardiovascular disease independent of sleep duration and cardiac genetic risk. J Intern Med, 300(3):360-378, 2026. doi:10.1111/joim.70133 Evidence: Low

     Verified 2026-09-30 · PMID 42387174 · DOI 10.1111/joim.70133

     • What Matters: What sleep does to how long you live
     • Deep dive: How sleep affects how long you live

492. kunutsor2018jointassociations

     S. K. Kunutsor et al. Joint associations of sauna bathing and cardiorespiratory fitness on cardiovascular and all-cause mortality risk: a long-term prospective cohort study. Ann Med, 50(2):139-146, 2018. doi:10.1080/07853890.2017.1387927 Evidence: Low

     Verified 2026-09-26 · PMID 28972808 · DOI 10.1080/07853890.2017.1387927

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Heat exposure
     • Deep dive: Does the sauna actually make you live longer?

493. kunutsor2018saunabathing

     S. K. Kunutsor et al. Sauna bathing reduces the risk of stroke in Finnish men and women: A prospective cohort study. Neurology, 90(22):e1937-e1944, 2018. doi:10.1212/WNL.0000000000005606 Evidence: Low

     Verified 2026-09-26 · PMID 29720543 · DOI 10.1212/WNL.0000000000005606

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Heat exposure
     • Deep dive: Does the sauna actually make you live longer?

494. kuriyama2006greentea

     S. Kuriyama et al. Green tea consumption and mortality due to cardiovascular disease, cancer, and all causes in Japan: the Ohsaki study. JAMA, 296(10):1255-65, 2006. doi:10.1001/jama.296.10.1255 Evidence: Low

     Verified 2026-09-27 · PMID 16968850 · DOI 10.1001/jama.296.10.1255

     • Wiki: Coffee, tea and energy drinks
     • Deep dive: The 7 things to know about coffee, tea, and energy drinks
     • Quiz: Caffeine check

495. kuzma2018strokedementia

     E. Kuźma et al. Stroke and dementia risk: A systematic review and meta-analysis. Alzheimers Dement, 14(11):1416-1426, 2018. doi:10.1016/j.jalz.2018.06.3061 Evidence: Moderate

     Verified 2026-09-26 · PMID 30177276 · DOI 10.1016/j.jalz.2018.06.3061

     • Wiki: Dementia risk factors
     • Deep dive: How to escape dementia: all 14 risk factors, ranked

496. kwok2018sleepquality

     C. S. Kwok et al. Self-Reported Sleep Duration and Quality and Cardiovascular Disease and Mortality: A Dose-Response Meta-Analysis. J Am Heart Assoc, 7(15):e008552, 2018. doi:10.1161/JAHA.118.008552 Evidence: Moderate

     Verified 2026-09-30 · PMID 30371228 · DOI 10.1161/JAHA.118.008552

     • What Matters: What sleep does to how long you live
     • Deep dive: How sleep affects how long you live
     • What Matters: The healthiest habits, ranked

497. kwok2019dietarycomponents

     C. S. Kwok et al. Dietary components and risk of cardiovascular disease and all-cause mortality: a review of evidence from meta-analyses. Eur J Prev Cardiol, 26(13):1415-1429, 2019. doi:10.1177/2047487319843667 Evidence: Moderate

     Verified 2026-10-01 · PMID 30971126 · DOI 10.1177/2047487319843667

     • Wiki: Nuts
     • Wiki: Leafy greens
     • Wiki: Cruciferous vegetables
     • What Matters: Foods ranked for longevity

498. kyle2023sleeprestriction

     S. D. Kyle et al. Clinical and cost-effectiveness of nurse-delivered sleep restriction therapy for insomnia in primary care (HABIT): a pragmatic, superiority, open-label, randomised controlled trial. Lancet, 402(10406):975-987, 2023. doi:10.1016/S0140-6736(23)00683-9 Evidence: Moderate

     Verified 2026-10-02 · PMID 37573859 · DOI 10.1016/S0140-6736(23)00683-9

     • Deep dive: Bryan Johnson's Ten Sleep Power Laws: what each one asks and how strong the evidence is
     • Deep dive: Top 10 insomnia remedies, ranked by the evidence
     • Quiz: Bryan Johnson's Ten Sleep Power Laws

499. kyungsook2018maritalsuicide

     W. Kyung-Sook et al. Marital status integration and suicide: A meta-analysis and meta-regression. Soc Sci Med, 197:116-126, 2018. doi:10.1016/j.socscimed.2017.11.053 Evidence: High

     Verified 2026-09-26 · PMID 29227910 · DOI 10.1016/j.socscimed.2017.11.053

     Metadata confirmed against the Europe PMC MEDLINE record for this PMID (NCBI E-utilities unavailable 2026-09-26). Author names are given as indexed by MEDLINE (given and family names appear inverted in the index); no issue number in the record.

     • What Matters: Factors linked to suicide deaths

500. lacaille2017closingra

     D. Lacaille et al. Improvement in 5-year mortality in incident rheumatoid arthritis compared with the general population-closing the mortality gap. Ann Rheum Dis, 76(6):1057-1063, 2017. doi:10.1136/annrheumdis-2016-209562 Evidence: Low

     Verified 2026-09-27 · PMID 28031164 · DOI 10.1136/annrheumdis-2016-209562

     • Wiki: Inflammation and aging
     • Deep dive: The 9 things that matter most for taming inflammation
     • Quiz: Preventive care

501. lachiewicz2008scalpneck

     A. M. Lachiewicz et al. Survival differences between patients with scalp or neck melanoma and those with melanoma of other sites in the Surveillance, Epidemiology, and End Results (SEER) program. Arch Dermatol, 144(4):515-521, 2008. doi:10.1001/archderm.144.4.515 Evidence: Low

     Verified 2026-09-29 · PMID 18427046 · DOI 10.1001/archderm.144.4.515

     • Wiki: Hair loss
     • Wiki: Skin and hair (section)

502. lai2023whiterice

     H. Lai et al. White rice consumption and risk of cardiometabolic and cancer outcomes: A systematic review and dose-response meta-analysis of prospective cohort studies. Crit Rev Food Sci Nutr, 63(33):12476-12487, 2023. doi:10.1080/10408398.2022.2101984 Evidence: Moderate

     Verified 2026-10-01 · PMID 35852223 · DOI 10.1080/10408398.2022.2101984

     • Wiki: White rice

503. lancet2025dailysteps

     D. Ding et al. Daily steps and health outcomes in adults: a systematic review and dose-response meta-analysis. Lancet Public Health, 10(8):e668-e681, 2025. doi:10.1016/s2468-2667(25)00164-1 Evidence: Moderate

     Verified 2026-09-27 · PMID 40713949 · DOI 10.1016/s2468-2667(25)00164-1

     • Wiki: Walking and daily steps
     • Wiki: Cardiovascular disease
     • Deep dive: The 10 things that matter most for your heart
     • Deep dive: The 8 things that matter most in exercise

504. lancet2025menopausehormone

     M. Melville et al. Menopause hormone therapy and risk of mild cognitive impairment or dementia: a systematic review and meta-analysis. Lancet Healthy Longev, 6(12):100803, 2025. doi:10.1016/j.lanhl.2025.100803 Evidence: Low

     Verified 2026-09-26 · PMID 41448220 · DOI 10.1016/j.lanhl.2025.100803

     • What Matters: What raises dementia risk most
     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • What Matters: Factors behind Alzheimer’s death risk

505. lane2024upf

     M. M. Lane et al. Ultra-processed food exposure and adverse health outcomes: umbrella review of epidemiological meta-analyses. BMJ, 384:e077310, 2024. doi:10.1136/bmj-2023-077310 Evidence: Moderate

     Verified 2026-10-01 · PMID 38418082 · DOI 10.1136/bmj-2023-077310

     • Wiki: Ultra-processed foods
     • Wiki: Foods (section)
     • What Matters: Foods ranked for longevity

506. langade2019ashwagandha

     D. Langade et al. Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study. Cureus, 11(9):e5797, 2019. doi:10.7759/cureus.5797 Evidence: Low

     Verified 2026-09-22 · PMID 31728244 · DOI 10.7759/cureus.5797

     • Wiki: Ashwagandha (supplement)

507. lange2024alcoholsuicide

     S. Lange et al. A dose-response meta-analysis on the relationship between average amount of alcohol consumed and death by suicide. Drug Alcohol Depend, 260:111348, 2024. doi:10.1016/j.drugalcdep.2024.111348 Evidence: Moderate

     Verified 2026-09-26 · PMID 38820908 · DOI 10.1016/j.drugalcdep.2024.111348

     Metadata confirmed against the Europe PMC MEDLINE record for this PMID (NCBI E-utilities unavailable 2026-09-26). Article number, no issue.

     • Wiki: Alcohol
     • What Matters: Factors linked to suicide deaths

508. langenberg2012waistbmi

     InterAct Consortium et al. Long-term risk of incident type 2 diabetes and measures of overall and regional obesity: the EPIC-InterAct case-cohort study. PLoS Med, 9(6):e1001230, 2012. doi:10.1371/journal.pmed.1001230 Evidence: Moderate

     Verified 2026-09-27 · PMID 22679397 · DOI 10.1371/journal.pmed.1001230

     • Wiki: Metabolic health and type 2 diabetes
     • Deep dive: The 9 factors that decide your type 2 diabetes risk

509. larsson2005diabetesmellitus

     S. C. Larsson, N. Orsini, and A. Wolk. Diabetes mellitus and risk of colorectal cancer: a meta-analysis. J Natl Cancer Inst, 97(22):1679-87, 2005. doi:10.1093/jnci/dji375 Evidence: High

     Verified 2026-09-26 · PMID 16288121 · DOI 10.1093/jnci/dji375

     • What Matters: What changes bowel cancer death risk

510. larsson2012redprocessed

     S. C. Larsson and A. Wolk. Red and processed meat consumption and risk of pancreatic cancer: meta-analysis of prospective studies. Br J Cancer, 106(3):603-7, 2012. doi:10.1038/bjc.2011.585 Evidence: Moderate

     Verified 2026-09-26 · PMID 22240790 · DOI 10.1038/bjc.2011.585

     • What Matters: What moves pancreatic cancer death risk

511. larsson2014meat

     S. C. Larsson and N. Orsini. Red meat and processed meat consumption and all-cause mortality: a meta-analysis. Am J Epidemiol, 179(3):282-9, 2014. doi:10.1093/aje/kwt261 Evidence: High

     Verified 2026-10-01 · PMID 24148709 · DOI 10.1093/aje/kwt261

     • Wiki: Red meat
     • Wiki: Processed meat

512. larsson2016alcoholconsumption

     S. C. Larsson et al. Differing association of alcohol consumption with different stroke types: a systematic review and meta-analysis. BMC Med, 14(1):178, 2016. doi:10.1186/s12916-016-0721-4 Evidence: High

     Verified 2026-09-26 · PMID 27881167 · DOI 10.1186/s12916-016-0721-4

     • Wiki: Alcohol
     • What Matters: What raises — or cuts — stroke death risk

513. lauersen2014sportsinjury

     J. B. Lauersen, D. M. Bertelsen, and L. B. Andersen. The effectiveness of exercise interventions to prevent sports injuries: a systematic review and meta-analysis of randomised controlled trials. Br J Sports Med, 48(11):871-877, 2014. doi:10.1136/bjsports-2013-092538 Evidence: Moderate

     Verified 2026-09-28 · PMID 24100287 · DOI 10.1136/bjsports-2013-092538

     • Wiki: Flexibility and mobility
     • Wiki: Balance, mobility and function (section)

514. laukkanen2015associationbetween

     T. Laukkanen et al. Association between sauna bathing and fatal cardiovascular and all-cause mortality events. JAMA Intern Med, 175(4):542-8, 2015. doi:10.1001/jamainternmed.2014.8187 Evidence: Low

     Verified 2026-09-27 · PMID 25705824 · DOI 10.1001/jamainternmed.2014.8187

     • Wiki: Heat exposure
     • Deep dive: Does the sauna actually make you live longer?
     • What Matters: What Affects Lifespan the Most

515. laukkanen2017saunabathing

     T. Laukkanen et al. Sauna bathing is inversely associated with dementia and Alzheimer's disease in middle-aged Finnish men. Age Ageing, 46(2):245-249, 2017. doi:10.1093/ageing/afw212 Evidence: Low

     Verified 2026-09-27 · PMID 27932366 · DOI 10.1093/ageing/afw212

     • Wiki: Heat exposure
     • Deep dive: Does the sauna actually make you live longer?

516. laukkanen2018cardiovascularother

     J. A. Laukkanen, T. Laukkanen, and S. K. Kunutsor. Cardiovascular and Other Health Benefits of Sauna Bathing: A Review of the Evidence. Mayo Clin Proc, 93(8):1111-1121, 2018. doi:10.1016/j.mayocp.2018.04.008 Evidence: Not graded (review)

     Verified 2026-09-27 · PMID 30077204 · DOI 10.1016/j.mayocp.2018.04.008

     • Wiki: Heat exposure
     • Deep dive: Does the sauna actually make you live longer?
     • Deep dive: Are hot tubs good for your health and longevity?

517. laukkanen2018saunabathing

     T. Laukkanen et al. Sauna bathing is associated with reduced cardiovascular mortality and improves risk prediction in men and women: a prospective cohort study. BMC Med, 16(1):219, 2018. doi:10.1186/s12916-018-1198-0 Evidence: Low

     Verified 2026-09-26 · PMID 30486813 · DOI 10.1186/s12916-018-1198-0

     • Wiki: Heat exposure
     • Deep dive: Does the sauna actually make you live longer?

518. laukkanen2024multifacetedbenefits

     J. A. Laukkanen and S. K. Kunutsor. The multifaceted benefits of passive heat therapies for extending the healthspan: A comprehensive review with a focus on Finnish sauna. Temperature (Austin), 11(1):27-51, 2024. doi:10.1080/23328940.2023.2300623 Evidence: Not graded (review)

     Verified 2026-09-27 · PMID 38577299 · DOI 10.1080/23328940.2023.2300623

     • Wiki: Heat exposure
     • Deep dive: Are hot tubs good for your health and longevity?

519. layyee2023socialisolation

     R. Lay-Yee et al. Social isolation from childhood to mid-adulthood: is there an association with older brain age?. Psychol Med, 53(16):7874-7882, 2023. doi:10.1017/s0033291723001964 Evidence: Very low

     Verified 2026-09-27 · PMID 37485695 · DOI 10.1017/s0033291723001964

     • Wiki: Cognitive aging
     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

520. lee2003physicalactivity

     C. D. Lee, A. R. Folsom, and S. N. Blair. Physical activity and stroke risk: a meta-analysis. Stroke, 34(10):2475-81, 2003. doi:10.1161/01.STR.0000091843.02517.9D Evidence: High

     Verified 2026-09-26 · PMID 14500932 · DOI 10.1161/01.STR.0000091843.02517.9D

     • What Matters: What raises — or cuts — stroke death risk

521. lee2013diabetesmellitus

     J. Y. Lee et al. Diabetes mellitus as an independent risk factor for lung cancer: a meta-analysis of observational studies. Eur J Cancer, 49(10):2411-23, 2013. doi:10.1016/j.ejca.2013.02.025 Evidence: Moderate

     Verified 2026-09-26 · PMID 23562551 · DOI 10.1016/j.ejca.2013.02.025

     • What Matters: Smoking and the rest: lung cancer death risk

522. lee2014leisuretime

     D. C. Lee et al. Leisure-time running reduces all-cause and cardiovascular mortality risk. J Am Coll Cardiol, 64(5):472-81, 2014. doi:10.1016/j.jacc.2014.04.058 Evidence: Low

     Verified 2026-09-26 · PMID 25082581 · DOI 10.1016/j.jacc.2014.04.058

     • Wiki: High-intensity interval training
     • Wiki: Sports and active hobbies
     • Deep dive: The sports that add the most years, ranked

523. lee201540second

     K. E. Lee et al. 40-second green roof views sustain attention: The role of micro-breaks in attention restoration. J Environ Psychol, 42:182-189, 2015. doi:10.1016/j.jenvp.2015.04.003 Evidence: Low

     Verified 2026-09-26 · DOI 10.1016/j.jenvp.2015.04.003

     • What Matters: What stretches, or shreds, attention

524. lee2015indoorplants

     M. S. Lee et al. Interaction with indoor plants may reduce psychological and physiological stress by suppressing autonomic nervous system activity in young adults: a randomized crossover study. Journal of Physiological Anthropology, 34(1):21, 2015. doi:10.1186/s40101-015-0060-8 Evidence: Low

     Verified 2026-09-27 · PMID 25928639 · DOI 10.1186/s40101-015-0060-8

     • Deep dive: Does having a pet actually help you live longer?

525. lee2019stepsolderwomen

     I. M. Lee et al. Association of Step Volume and Intensity With All-Cause Mortality in Older Women. JAMA Intern Med, 179(8):1105-1112, 2019. doi:10.1001/jamainternmed.2019.0899 Evidence: Low

     Verified 2026-09-28 · PMID 31141585 · DOI 10.1001/jamainternmed.2019.0899

     • Wiki: Walking and daily steps

526. lee2022activityintensity

     D. H. Lee et al. Long-Term Leisure-Time Physical Activity Intensity and All-Cause and Cause-Specific Mortality: A Prospective Cohort of US Adults. Circulation, 146(7):523-534, 2022. doi:10.1161/CIRCULATIONAHA.121.058162 Evidence: Moderate

     Verified 2026-09-28 · PMID 35876019 · DOI 10.1161/CIRCULATIONAHA.121.058162

     • Wiki: Zone 2 training
     • Wiki: High-intensity interval training

527. lee2022cataractsurgery

     C. S. Lee et al. Association Between Cataract Extraction and Development of Dementia. JAMA Intern Med, 182(2):134-141, 2022. doi:10.1001/jamainternmed.2021.6990 Evidence: Low

     Verified 2026-09-26 · PMID 34870676 · DOI 10.1001/jamainternmed.2021.6990

     • Wiki: Dementia risk factors
     • Wiki: Hearing and vision loss
     • Wiki: Brain health (section)
     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • Deep dive: Are your ears and eyes quietly aging your brain?
     • Quiz: Hearing & vision
     • Quiz: Hearing & vision check

528. lee2022lncsbsubstitution

     J. J. Lee et al. Relation of Change or Substitution of Low- and No-Calorie Sweetened Beverages With Cardiometabolic Outcomes: A Systematic Review and Meta-analysis of Prospective Cohort Studies. Diabetes Care, 45(8):1917-1930, 2022. doi:10.2337/dc21-2130 Evidence: Low

     Verified 2026-10-05 · PMID 35901272 · DOI 10.2337/dc21-2130

     • Deep dive: Diet soda vs regular soda vs water: what the evidence shows

529. lemyre2020presleepcognition

     A. Lemyre et al. Pre-sleep cognitive activity in adults: A systematic review. Sleep Med Rev, 50:101253, 2020. doi:10.1016/j.smrv.2019.101253 Evidence: Not graded (review)

     Verified 2026-10-08 · PMID 31918338 · DOI 10.1016/j.smrv.2019.101253

     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

530. leng2015sleepduration

     Y. Leng et al. Sleep duration and risk of fatal and nonfatal stroke: a prospective study and meta-analysis. Neurology, 84(11):1072-9, 2015. doi:10.1212/WNL.0000000000001371 Evidence: High

     Verified 2026-09-26 · PMID 25716357 · DOI 10.1212/WNL.0000000000001371

     • What Matters: What raises — or cuts — stroke death risk

531. leng2017sleepdisordered

     Y. Leng et al. Association of Sleep-Disordered Breathing With Cognitive Function and Risk of Cognitive Impairment: A Systematic Review and Meta-analysis. JAMA Neurol, 74(10):1237-1245, 2017. doi:10.1001/jamaneurol.2017.2180 Evidence: Moderate

     Verified 2026-09-26 · PMID 28846764 · DOI 10.1001/jamaneurol.2017.2180

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • What Matters: What raises dementia risk most
     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • What Matters: Factors behind Alzheimer’s death risk
     • What Matters: The healthiest habits, ranked

532. lennerz2021selfreported

     B. S. Lennerz et al. Behavioral Characteristics and Self-Reported Health Status among 2029 Adults Consuming a "Carnivore Diet". Curr Dev Nutr, 5(12):nzab133, 2021. doi:10.1093/cdn/nzab133 Evidence: Very low

     Verified 2026-09-26 · PMID 34934897 · DOI 10.1093/cdn/nzab133

     • Wiki: Dietary patterns
     • Deep dive: Vegan, vegetarian, omnivore, carnivore: what the labels actually buy you

533. leong2015gripstrength

     D. P. Leong et al. Prognostic value of grip strength: findings from the Prospective Urban Rural Epidemiology (PURE) study. Lancet, 386(9990):266-73, 2015. doi:10.1016/S0140-6736(14)62000-6 Evidence: Moderate

     Verified 2026-09-26 · PMID 25982160 · DOI 10.1016/S0140-6736(14)62000-6

     • Wiki: Grip strength
     • Wiki: Functional fitness
     • Wiki: Metabolic health and type 2 diabetes
     • Wiki: Body weight
     • Wiki: Strength and muscle (section)
     • What Matters: Movement: What Matters?
     • Deep dive: The 8 things that matter most for your metabolism
     • Deep dive: The 8 things that matter most in exercise
     • Deep dive: How much is the extra weight actually costing you?

534. lew2017redmeat

     Q. J. Lew et al. Red Meat Intake and Risk of ESRD. J Am Soc Nephrol, 28(1):304-312, 2017. doi:10.1681/ASN.2016030248 Evidence: Low

     Verified 2026-09-26 · PMID 27416946 · DOI 10.1681/ASN.2016030248

     Single cohort (Singapore Chinese Health Study, n=63,257).

     • What Matters: Factors that swing kidney disease deaths

535. lewington2002bloodpressure

     S. Lewington et al. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet, 360(9349):1903-13, 2002. doi:10.1016/s0140-6736(02)11911-8 Evidence: High

     Verified 2026-09-26 · PMID 12493255 · DOI 10.1016/s0140-6736(02)11911-8

     • Wiki: Blood pressure
     • Deep dive: Is your blood pressure quietly aging you? The 9 things that matter most
     • Quiz: Blood pressure check
     • What Matters: Habits that swing heart-disease death risk
     • What Matters: What raises — or cuts — stroke death risk

536. lewington2007bloodcholesterol

     Prospective Studies Collaboration et al. Blood cholesterol and vascular mortality by age, sex, and blood pressure: a meta-analysis of individual data from 61 prospective studies with 55,000 vascular deaths. Lancet, 370(9602):1829-39, 2007. doi:10.1016/S0140-6736(07)61778-4 Evidence: High

     Verified 2026-09-26 · PMID 18061058 · DOI 10.1016/S0140-6736(07)61778-4

     • Quiz: Heart health
     • What Matters: Habits that swing heart-disease death risk
     • What Matters: What raises — or cuts — stroke death risk

537. li2016physicalactivity

     T. Li et al. The dose-response effect of physical activity on cancer mortality: findings from 71 prospective cohort studies. Br J Sports Med, 50(6):339-45, 2016. doi:10.1136/bjsports-2015-094927 Evidence: High

     Verified 2026-09-26 · PMID 26385207 · DOI 10.1136/bjsports-2015-094927

     • What Matters: Habits that change cancer death risk

538. li2019effectshelicobacter

     W. Q. Li et al. Effects of Helicobacter pylori treatment and vitamin and garlic supplementation on gastric cancer incidence and mortality: follow-up of a randomized intervention trial. BMJ, 366:l5016, 2019. doi:10.1136/bmj.l5016 Evidence: Moderate

     Verified 2026-10-04 · PMID 31511230 · DOI 10.1136/bmj.l5016

     • Wiki: Helicobacter pylori
     • Deep dive: H. pylori and stomach cancer: what the evidence shows

539. li2020taichisleep

     H. Li et al. The Effect of Tai Chi for Improving Sleep Quality: A Systematic Review and Meta-analysis. J Affect Disord, 274:1102-1112, 2020. doi:10.1016/j.jad.2020.05.076 Evidence: Moderate

     Verified 2026-10-08 · PMID 32663938 · DOI 10.1016/j.jad.2020.05.076

     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

540. li2021leafygreens

     N. Li et al. Green leafy vegetable and lutein intake and multiple health outcomes. Food Chem, 360:130145, 2021. doi:10.1016/j.foodchem.2021.130145 Evidence: Moderate

     Verified 2026-10-01 · PMID 34034049 · DOI 10.1016/j.foodchem.2021.130145

     • Wiki: Leafy greens

541. li2022cruciferous

     N. Li et al. Cruciferous vegetable and isothiocyanate intake and multiple health outcomes. Food Chem, 375:131816, 2022. doi:10.1016/j.foodchem.2021.131816 Evidence: Moderate

     Verified 2026-10-01 · PMID 34929422 · DOI 10.1016/j.foodchem.2021.131816

     • Wiki: Cruciferous vegetables

542. li2022sweetenedbev

     H. Li et al. Association between intake of sweetened beverages with all-cause and cause-specific mortality: a systematic review and meta-analysis. J Public Health (Oxf), 44(3):516-526, 2022. doi:10.1093/pubmed/fdab069 Evidence: High

     Verified 2026-10-01 · PMID 33837431 · DOI 10.1093/pubmed/fdab069

     • Wiki: Sugary drinks

543. li2022ultraprocessedfood

     H. Li et al. Association of Ultraprocessed Food Consumption With Risk of Dementia: A Prospective Cohort Study. Neurology, 99(10):e1056-e1066, 2022. doi:10.1212/wnl.0000000000200871 Evidence: Low

     Verified 2026-09-27 · PMID 36219796 · DOI 10.1212/wnl.0000000000200871

     • Wiki: Dementia risk factors
     • Deep dive: Plants and your brain: what the vegetarian, Mediterranean and MIND studies really show about dementia

544. li2023nappingalzheimers

     P. Li et al. Daytime napping and Alzheimer's dementia: A potential bidirectional relationship. Alzheimers Dement, 19(1):158-168, 2023. doi:10.1002/alz.12636 Evidence: Low

     Verified 2026-09-29 · PMID 35297533 · DOI 10.1002/alz.12636

     • Wiki: Naps

545. li2023petownership

     Y. Li et al. Pet Ownership, Living Alone, and Cognitive Decline Among Adults 50 Years and Older. JAMA Netw Open, 6(12):e2349241, 2023. doi:10.1001/jamanetworkopen.2023.49241 Evidence: Low

     Verified 2026-09-27 · PMID 38147332 · DOI 10.1001/jamanetworkopen.2023.49241

     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

546. li2024fivesleep

     H. Li et al. Association of healthy sleep patterns with risk of mortality and life expectancy at age of 30 years: a population-based cohort study. QJM, 117(3):177-186, 2024. doi:10.1093/qjmed/hcad237 Evidence: Low

     Verified 2026-09-26 · PMID 37831896 · DOI 10.1093/qjmed/hcad237

     • Wiki: Sleep physiology
     • Wiki: Sleep duration and mortality
     • Wiki: Sleep (section)
     • What Matters: What sleep does to how long you live
     • Deep dive: How sleep affects how long you live
     • What Matters: The healthiest habits, ranked

547. li2025longterm

     Y. Li et al. Long-Term Intake of Red Meat in Relation to Dementia Risk and Cognitive Function in US Adults. Neurology, 104(3):e210286, 2025. doi:10.1212/WNL.0000000000210286 Evidence: Moderate

     Verified 2026-09-26 · PMID 39813632 · DOI 10.1212/WNL.0000000000210286

     • Deep dive: Plants and your brain: what the vegetarian, Mediterranean and MIND studies really show about dementia

548. li2025sugarsweetened

     Y. Li et al. Association of Sugar-Sweetened, Artificially Sweetened, and Unsweetened Coffee Consumption with Chronic Liver Disease and Liver-Related Events: A Large Prospective Cohort Study. J Nutr, 155(3):975-984, 2025. doi:10.1016/j.tjnut.2025.01.009 Evidence: Low

     Verified 2026-09-26 · PMID 39800310 · DOI 10.1016/j.tjnut.2025.01.009

     • What Matters: Factors that swing liver disease deaths

549. li2026pmrsleep

     K. Li et al. The effects of progressive muscle relaxation on sleep quality in adults: a systematic review and meta-analysis of randomized controlled trials. Front Public Health, 14:1906525, 2026. doi:10.3389/fpubh.2026.1906525 Evidence: Low

     Verified 2026-10-08 · PMID 42625730 · DOI 10.3389/fpubh.2026.1906525

     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

550. liang2024outdoorgardening

     J. H. Liang, M. L. Liu, and S. Y. Huang. Outdoor gardening activity with different frequency and duration may be associated with reduction of total and cause-specific mortality risk for general U.S. adults: Findings from the NHANES. Nutrition, Metabolism and Cardiovascular Diseases, 34(6):1496-1507, 2024. doi:10.1016/j.numecd.2024.02.010 Evidence: Low

     Verified 2026-09-27 · PMID 38658226 · DOI 10.1016/j.numecd.2024.02.010

     • Deep dive: Does having a pet actually help you live longer?

551. liang2025upf

     S. Liang et al. Ultra-processed foods and risk of all-cause mortality: an updated systematic review and dose-response meta-analysis of prospective cohort studies. Syst Rev, 14(1):53, 2025. doi:10.1186/s13643-025-02800-8 Evidence: Moderate

     Verified 2026-10-01 · PMID 40033461 · DOI 10.1186/s13643-025-02800-8

     • Wiki: Ultra-processed foods

552. lim2010totalsleep

     J. Lim and D. F. Dinges. A meta-analysis of the impact of short-term sleep deprivation on cognitive variables. Psychol Bull, 136(3):375-89, 2010. doi:10.1037/a0018883 Evidence: Moderate

     Verified 2026-09-26 · PMID 20438143 · DOI 10.1037/a0018883

     • What Matters: What stretches, or shreds, attention

553. lin2011hearingloss

     F. R. Lin et al. Hearing loss and cognition in the Baltimore Longitudinal Study of Aging. Neuropsychology, 25(6):763-70, 2011. doi:10.1037/a0024238 Evidence: Very low

     Verified 2026-09-26 · PMID 21728425 · DOI 10.1037/a0024238

     • Wiki: Cognitive aging
     • Wiki: Hearing and vision loss
     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

554. lin2011hearingloss2

     F. R. Lin et al. Hearing loss and incident dementia. Arch Neurol, 68(2):214-20, 2011. doi:10.1001/archneurol.2010.362 Evidence: Low

     Verified 2026-09-26 · PMID 21320988 · DOI 10.1001/archneurol.2010.362

     • Wiki: Dementia risk factors
     • Wiki: Hearing and vision loss
     • Wiki: Brain health (section)
     • Deep dive: Are your ears and eyes quietly aging your brain?

555. lin2023achievehearing

     F. R. Lin et al. Hearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): a multicentre, randomised controlled trial. Lancet, 402(10404):786-797, 2023. doi:10.1016/S0140-6736(23)01406-X Evidence: Moderate

     Verified 2026-09-26 · PMID 37478886 · DOI 10.1016/S0140-6736(23)01406-X

     • Wiki: Dementia risk factors
     • Wiki: Hearing and vision loss
     • What Matters: What moves your cognitive age
     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • Deep dive: Are your ears and eyes quietly aging your brain?
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • Quiz: Hearing & vision
     • Quiz: Hearing & vision check
     • What Matters: The healthiest habits, ranked

556. linawhoilo

     J. Li et al. The effect of exposure to long working hours on ischaemic heart disease: A systematic review and meta-analysis from the WHO/ILO Joint Estimates of the Work-related Burden of Disease and Injury. Environ Int, 142:105739, 2020. doi:10.1016/j.envint.2020.105739 Evidence: Moderate

     Verified 2026-09-26 · PMID 32505014 · DOI 10.1016/j.envint.2020.105739

     • What Matters: Habits that swing heart-disease death risk

557. lincoff2023semaglutidecardiovascular

     A. M. Lincoff et al. Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes. N Engl J Med, 389(24):2221-2232, 2023. doi:10.1056/NEJMoa2307563 Evidence: Moderate

     Verified 2026-09-26 · PMID 37952131 · DOI 10.1056/NEJMoa2307563

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Body weight
     • Deep dive: How much is the extra weight actually costing you?
     • What Matters: Habits that swing heart-disease death risk

558. lindson2023pharmacologicalelectronic

     N. Lindson et al. Pharmacological and electronic cigarette interventions for smoking cessation in adults: component network meta-analyses. Cochrane Database Syst Rev, 9(9):CD015226, 2023. doi:10.1002/14651858.cd015226.pub2 Evidence: High

     Verified 2026-09-27 · PMID 37696529 · DOI 10.1002/14651858.cd015226.pub2

     Automated link-check got HTTP 412 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Smoking
     • Wiki: Alcohol and tobacco (section)
     • Deep dive: Smoking takes about ten years. Here is what quitting gives back

559. lindson2024electroniccigarettes

     N. Lindson et al. Electronic cigarettes for smoking cessation. Cochrane Database Syst Rev, 1(1):CD010216, 2024. doi:10.1002/14651858.cd010216.pub8 Evidence: High

     Verified 2026-09-27 · PMID 38189560 · DOI 10.1002/14651858.cd010216.pub8

     Automated link-check got HTTP 412 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Smoking
     • Deep dive: Smoking takes about ten years. Here is what quitting gives back
     • Quiz: Smoking check

560. litt2023communitygardening

     J. S. Litt, K. Alaimo, and K. K. Harrall. Effects of a community gardening intervention on diet, physical activity, and anthropometry outcomes in the USA (CAPS): an observer-blind, randomised controlled trial. The Lancet Planetary Health, 7(1):e23-e32, 2023. doi:10.1016/S2542-5196(22)00303-5 Evidence: Moderate

     Verified 2026-09-27 · PMID 36608945 · DOI 10.1016/S2542-5196(22)00303-5

     • Wiki: Sports and active hobbies
     • Deep dive: Does having a pet actually help you live longer?

561. liu2008motorcyclehelmets

     B. C. Liu et al. Helmets for preventing injury in motorcycle riders. Cochrane Database Syst Rev, 2008(1):CD004333, 2008. doi:10.1002/14651858.CD004333.pub3 Evidence: High

     Verified 2026-09-29 · PMID 18254047 · DOI 10.1002/14651858.CD004333.pub3

     • Wiki: Road safety

562. liu2009separatejoint

     B. Liu et al. Separate and joint effects of alcohol and smoking on the risks of cirrhosis and gallbladder disease in middle-aged women. Am J Epidemiol, 169(2):153-60, 2009. doi:10.1093/aje/kwn280 Evidence: Low

     Verified 2026-09-26 · PMID 19033524 · DOI 10.1093/aje/kwn280

     • What Matters: Factors that swing liver disease deaths

563. liu2010bodymass

     B. Liu et al. Body mass index and risk of liver cirrhosis in middle aged UK women: prospective study. BMJ, 340:c912, 2010. doi:10.1136/bmj.c912 Evidence: Low

     Verified 2026-09-26 · PMID 20223875 · DOI 10.1136/bmj.c912

     BMJ electronic-article number c912; no issue number.

     • What Matters: Factors that swing liver disease deaths

564. liu2011doesphysical

     Y. Liu et al. Does physical activity reduce the risk of prostate cancer? A systematic review and meta-analysis. Eur Urol, 60(5):1029-44, 2011. doi:10.1016/j.eururo.2011.07.007 Evidence: Moderate

     Verified 2026-09-26 · PMID 21802197 · DOI 10.1016/j.eururo.2011.07.007

     • What Matters: Levers on prostate cancer death risk

565. liu2013fruitvegetables

     J. Liu et al. Intake of fruit and vegetables and risk of esophageal squamous cell carcinoma: a meta-analysis of observational studies. Int J Cancer, 133(2):473-85, 2013. doi:10.1002/ijc.28024 Evidence: Moderate

     Verified 2026-09-26 · PMID 23319052 · DOI 10.1002/ijc.28024

     • What Matters: Factors that swing esophageal cancer deaths

566. liu2020secondhandsmoking

     W. Liu et al. Secondhand smoking and neurological disease: a meta-analysis of cohort studies. Rev Environ Health, 36(2):271-277, 2020. doi:10.1515/reveh-2020-0053 Evidence: High

     Verified 2026-09-26 · PMID 33128528 · DOI 10.1515/reveh-2020-0053

     • What Matters: What raises — or cuts — stroke death risk

567. liu2022sweetenedvs

     D. Liu et al. Association of Sugar-Sweetened, Artificially Sweetened, and Unsweetened Coffee Consumption With All-Cause and Cause-Specific Mortality : A Large Prospective Cohort Study. Ann Intern Med, 175(7):909-917, 2022. doi:10.7326/M21-2977 Evidence: Low

     Verified 2026-09-26 · PMID 35635846 · DOI 10.7326/M21-2977

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Coffee, tea and energy drinks
     • Deep dive: The 7 things to know about coffee, tea, and energy drinks

568. liu2026upfINCOMPLETE METADATA

     X. Liu et al. Ultra-processed food consumption and risk of multiple chronic diseases among 8,819,894 adults from 51 prospective cohorts: a dose-response meta-analysis. Fam Med Community Health, 14(Suppl 5), 2026. doi:10.1136/fmch-2026-003925 Evidence: Moderate

     Verified 2026-10-01 · PMID 42773062 · DOI 10.1136/fmch-2026-003925

     PubMed lists no pages for this paper yet (checked 2026-10-01).

     • Wiki: Ultra-processed foods

569. livingston2020dementiaprevention

     G. Livingston et al. Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. Lancet, 396(10248):413-446, 2020. doi:10.1016/S0140-6736(20)30367-6 Evidence: Not graded (review)

     Verified 2026-09-26 · PMID 32738937 · DOI 10.1016/S0140-6736(20)30367-6

     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • Deep dive: Are your ears and eyes quietly aging your brain?

570. livingston2024dementia

     G. Livingston et al. Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission. Lancet, 404(10452):572-628, 2024. doi:10.1016/S0140-6736(24)01296-0 Evidence: Not graded (review)

     Verified 2026-09-26 · PMID 39096926 · DOI 10.1016/S0140-6736(24)01296-0

     • Wiki: Dementia risk factors
     • Wiki: Hearing and vision loss
     • Wiki: Brain health (section)
     • What Matters: What raises dementia risk most
     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • Deep dive: What you inherit from your family, and what you don’t
     • Deep dive: Are your ears and eyes quietly aging your brain?
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • Deep dive: Plants and your brain: what the vegetarian, Mediterranean and MIND studies really show about dementia
     • Quiz: Hearing & vision
     • Quiz: Hearing & vision check
     • What Matters: Factors behind Alzheimer’s death risk
     • What Matters: What Affects Lifespan the Most
     • What Matters: The healthiest habits, ranked

571. llamosasfalcon2024alcoholuse

     L. Llamosas-Falcón et al. How does alcohol use impact morbidity and mortality of liver cirrhosis? A systematic review and dose-response meta-analysis. Hepatol Int, 18(1):216-224, 2024. doi:10.1007/s12072-023-10584-z Evidence: High

     Verified 2026-09-26 · PMID 37684424 · DOI 10.1007/s12072-023-10584-z

     • What Matters: Factors that swing liver disease deaths

572. lloydjones2004parentalcvd

     D. M. Lloyd-Jones et al. Parental cardiovascular disease as a risk factor for cardiovascular disease in middle-aged adults: a prospective study of parents and offspring. JAMA, 291(18):2204-11, 2004. doi:10.1001/jama.291.18.2204 Evidence: Low

     Verified 2026-09-26 · PMID 15138242 · DOI 10.1001/jama.291.18.2204

     • Wiki: Family history and genetics
     • Deep dive: What you inherit from your family, and what you don’t
     • Quiz: Family history
     • Family: Early heart disease in close family
     • What Matters: Habits that swing heart-disease death risk
     • What Matters: What Affects Lifespan the Most

573. loomis2016veryhot

     D. Loomis et al. Carcinogenicity of drinking coffee, mate, and very hot beverages. Lancet Oncol, 17(7):877-878, 2016. doi:10.1016/s1470-2045(16)30239-x Evidence: Not graded (guideline)

     Verified 2026-09-27 · PMID 27318851 · DOI 10.1016/s1470-2045(16)30239-x

     • Deep dive: The 7 things to know about coffee, tea, and energy drinks

574. lopezotin2013hallmarks

     C. López-Otín et al. The hallmarks of aging. Cell, 153(6):1194-217, 2013. doi:10.1016/j.cell.2013.05.039 Evidence: Very low

     Verified 2026-09-28 · PMID 23746838 · DOI 10.1016/j.cell.2013.05.039

     • Wiki: Telomeres
     • Wiki: Inflammation and aging
     • Wiki: Longevity theories (section)

575. lopezotin2023hallmarks

     C. López-Otín et al. Hallmarks of aging: An expanding universe. Cell, 186(2):243-278, 2023. doi:10.1016/j.cell.2022.11.001 Evidence: Very low

     Verified 2026-09-22 · PMID 36599349 · DOI 10.1016/j.cell.2022.11.001

     Cited from both the telomeres and inflammation wiki pages; one registry entry, two citers.

     • Wiki: Telomeres
     • Wiki: Inflammation and aging
     • Wiki: Longevity theories (section)

576. lorenz2007milktea

     M. Lorenz et al. Addition of milk prevents vascular protective effects of tea. Eur Heart J, 28(2):219-23, 2007. doi:10.1093/eurheartj/ehl442 Evidence: Low

     Verified 2026-09-27 · PMID 17213230 · DOI 10.1093/eurheartj/ehl442

     • Wiki: Coffee, tea and energy drinks
     • Deep dive: The 7 things to know about coffee, tea, and energy drinks

577. losier1996errorpatterns

     B. J. Losier, P. J. McGrath, and R. M. Klein. Error patterns on the continuous performance test in non-medicated and medicated samples of children with and without ADHD: a meta-analytic review. J Child Psychol Psychiatry, 37(8):971-87, 1996. doi:10.1111/j.1469-7610.1996.tb01494.x Evidence: Moderate

     Verified 2026-09-27 · PMID 9119944 · DOI 10.1111/j.1469-7610.1996.tb01494.x

     • What Matters: What stretches, or shreds, attention

578. lovato2019insomniamortality

     N. Lovato and L. Lack. Insomnia and mortality: A meta-analysis. Sleep Med Rev, 43:71-83, 2019. doi:10.1016/j.smrv.2018.10.004 Evidence: Moderate

     Verified 2026-09-28 · PMID 30529432 · DOI 10.1016/j.smrv.2018.10.004

     • Wiki: Insomnia

579. lowe2017sleeprestriction

     C. J. Lowe, A. Safati, and P. A. Hall. The neurocognitive consequences of sleep restriction: A meta-analytic review. Neurosci Biobehav Rev, 80:586-604, 2017. doi:10.1016/j.neubiorev.2017.07.010 Evidence: Moderate

     Verified 2026-09-27 · PMID 28757454 · DOI 10.1016/j.neubiorev.2017.07.010

     • What Matters: What stretches, or shreds, attention

580. lu2024soy

     T. Y. Lu et al. Associations of soy product intake with all-cause, cardiovascular disease and cancer mortality: Guangzhou Biobank Cohort Study and updated meta-analyses. Eur J Nutr, 63(5):1731-1745, 2024. doi:10.1007/s00394-024-03363-5 Evidence: Moderate

     Verified 2026-10-01 · PMID 38520523 · DOI 10.1007/s00394-024-03363-5

     • Wiki: Soy foods
     • What Matters: Foods ranked for longevity

581. lucentefortenapanc4ann

     E. Lucenteforte et al. Alcohol consumption and pancreatic cancer: a pooled analysis in the International Pancreatic Cancer Case-Control Consortium (PanC4). Ann Oncol, 23(2):374-82, 2012. doi:10.1093/annonc/mdr120 Evidence: Moderate

     Verified 2026-09-26 · PMID 21536662 · DOI 10.1093/annonc/mdr120

     • What Matters: What moves pancreatic cancer death risk

582. luders2016estimatingbrain

     E. Luders, N. Cherbuin, and C. Gaser. Estimating brain age using high-resolution pattern recognition: Younger brains in long-term meditation practitioners. Neuroimage, 134:508-513, 2016. doi:10.1016/j.neuroimage.2016.04.007 Evidence: Very low

     Verified 2026-09-26 · PMID 27079530 · DOI 10.1016/j.neuroimage.2016.04.007

     • Wiki: Cognitive aging
     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

583. ludyga2016acuteexercise

     S. Ludyga et al. Acute effects of moderate aerobic exercise on specific aspects of executive function in different age and fitness groups: A meta-analysis. Psychophysiology, 53(11):1611-1626, 2016. doi:10.1111/psyp.12736 Evidence: Moderate

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • What Matters: What stretches, or shreds, attention

584. lunet2005fruitvegetable

     N. Lunet, A. Lacerda-Vieira, and H. Barros. Fruit and vegetables consumption and gastric cancer: a systematic review and meta-analysis of cohort studies. Nutr Cancer, 53(1):1-10, 2005. doi:10.1207/s15327914nc5301_1 Evidence: Low

     Verified 2026-09-26 · PMID 16351501 · DOI 10.1207/s15327914nc5301_1

     • What Matters: What raises stomach cancer death risk

585. luo2014meatconsumption

     J. Luo et al. Systematic review with meta-analysis: meat consumption and the risk of hepatocellular carcinoma. Aliment Pharmacol Ther, 39(9):913-22, 2014. doi:10.1111/apt.12678 Evidence: Moderate

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     • What Matters: Habits behind liver cancer death risk

586. lupoli2021whitemeatINCOMPLETE METADATA

     R. Lupoli et al. White Meat Consumption, All-Cause Mortality, and Cardiovascular Events: A Meta-Analysis of Prospective Cohort Studies. Nutrients, 13(2), 2021. doi:10.3390/nu13020676 Evidence: High

     Verified 2026-10-01 · PMID 33672599 · DOI 10.3390/nu13020676

     PubMed lists no pages for this paper yet (checked 2026-10-01).

     • Wiki: Poultry

587. ma2013obesityrisk

     Y. Ma et al. Obesity and risk of colorectal cancer: a systematic review of prospective studies. PLoS One, 8(1):e53916, 2013. doi:10.1371/journal.pone.0053916 Evidence: High

     Verified 2026-09-27 · PMID 23349764 · DOI 10.1371/journal.pone.0053916

     • Wiki: Colon health
     • Deep dive: The 9 things that matter most for your colon
     • What Matters: What changes bowel cancer death risk

588. ma2022addedsalt

     H. Ma et al. Adding salt to foods and hazard of premature mortality. Eur Heart J, 43(30):2878-2888, 2022. doi:10.1093/eurheartj/ehac208 Evidence: Low

     Verified 2026-10-01 · PMID 35808995 · DOI 10.1093/eurheartj/ehac208

     • Wiki: Salt added at the table
     • What Matters: Foods ranked for longevity

589. ma2023essential8

     H. Ma et al. Cardiovascular Health and Life Expectancy Among Adults in the United States. Circulation, 147(15):1137-1146, 2023. doi:10.1161/CIRCULATIONAHA.122.062457 Evidence: Low

     Verified 2026-09-26 · PMID 37036905 · DOI 10.1161/CIRCULATIONAHA.122.062457

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Cardiovascular disease
     • Wiki: Heart and metabolic health (section)
     • Deep dive: The 10 things that matter most for your heart

590. ma2024sleeptiming

     M. Ma et al. Association of sleep timing with all-cause and cardiovascular mortality: the Sleep Heart Health Study and the Osteoporotic Fractures in Men Study. J Clin Sleep Med, 20(4):545-553, 2024. doi:10.5664/jcsm.10926 Evidence: Low

     Verified 2026-09-30 · PMID 38561941 · DOI 10.5664/jcsm.10926

     • What Matters: What sleep does to how long you live
     • Deep dive: How sleep affects how long you live
     • What Matters: The healthiest habits, ranked

591. maas2009socialcontacts

     J. Maas et al. Social contacts as a possible mechanism behind the relation between green space and health. Health Place, 15(2):586-595, 2009. doi:10.1016/j.healthplace.2008.09.006 Evidence: Very low

     Verified 2026-09-26 · PMID 19022699 · DOI 10.1016/j.healthplace.2008.09.006

     • Wiki: Green space
     • Deep dive: Does living somewhere green actually help you live longer?

592. madjd2015dietwater

     A. Madjd et al. Effects on weight loss in adults of replacing diet beverages with water during a hypoenergetic diet: a randomized, 24-wk clinical trial. Am J Clin Nutr, 102(6):1305-12, 2015. doi:10.3945/ajcn.115.109397 Evidence: Low

     Verified 2026-10-05 · PMID 26537940 · DOI 10.3945/ajcn.115.109397

     • Deep dive: Diet soda vs regular soda vs water: what the evidence shows

593. madsen2023fruitvegetable

     H. Madsen, A. Sen, and D. Aune. Fruit and vegetable consumption and the risk of hypertension: a systematic review and meta-analysis of prospective studies. Eur J Nutr, 62(5):1941-1955, 2023. doi:10.1007/s00394-023-03145-5 Evidence: Moderate

     Verified 2026-09-27 · PMID 37106252 · DOI 10.1007/s00394-023-03145-5

     • What Matters: Levers on hypertensive disease deaths

594. mah2021magnesiuminsomnia

     J. Mah and T. Pitre. Oral magnesium supplementation for insomnia in older adults: a Systematic Review & Meta-Analysis. BMC Complement Med Ther, 21(1):125, 2021. doi:10.1186/s12906-021-03297-z Evidence: Low

     Verified 2026-09-28 · PMID 33865376 · DOI 10.1186/s12906-021-03297-z

     • Wiki: Supplements (section)
     • Wiki: Magnesium (supplement)
     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

595. malfertheiner2022managementhelicobacter

     P. Malfertheiner et al. Management of Helicobacter pylori infection: the Maastricht VI/Florence consensus report. Gut, 71(9):1724-1762, 2022. doi:10.1136/gutjnl-2022-327745 Evidence: Not graded (guideline)

     Verified 2026-10-04 · PMID 35944925 · DOI 10.1136/gutjnl-2022-327745

     • Wiki: Helicobacter pylori
     • Deep dive: H. pylori and stomach cancer: what the evidence shows

596. malik2010sugarsweetened

     V. S. Malik et al. Sugar-sweetened beverages and risk of metabolic syndrome and type 2 diabetes: a meta-analysis. Diabetes Care, 33(11):2477-83, 2010. doi:10.2337/dc10-1079 Evidence: High

     Verified 2026-09-26 · PMID 20693348 · DOI 10.2337/dc10-1079

     • What Matters: What moves diabetes death odds

597. malik2019sugarsweetened

     V. S. Malik et al. Long-Term Consumption of Sugar-Sweetened and Artificially Sweetened Beverages and Risk of Mortality in US Adults. Circulation, 139(18):2113-2125, 2019. doi:10.1161/CIRCULATIONAHA.118.037401 Evidence: Moderate

     Verified 2026-09-26 · PMID 30882235 · DOI 10.1161/CIRCULATIONAHA.118.037401

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Dietary patterns
     • Wiki: Hydration
     • Wiki: Coffee, tea and energy drinks
     • Deep dive: The 7 things worth knowing about hydration
     • Deep dive: The 8 things that matter most on your plate
     • Deep dive: The 7 things to know about coffee, tea, and energy drinks
     • Deep dive: Diet soda vs regular soda vs water: what the evidence shows
     • Quiz: Diet
     • Quiz: Diet check
     • What Matters: Habits that swing heart-disease death risk

598. manabe2019oralcare

     K. Manabe et al. Preventive Effect of Oral Self-Care on Pneumonia Death among the Elderly with Tooth Loss: The Ohsaki Cohort 2006 Study. Tohoku J Exp Med, 247(4):251-257, 2019. doi:10.1620/tjem.247.251 Evidence: Low

     Verified 2026-09-26 · PMID 30996210 · DOI 10.1620/tjem.247.251

     Single Japanese community cohort (Ohsaki), adults 65+; observational.

     • What Matters: Factors that swing flu and pneumonia deaths

599. mandsager2018fitnessno

     K. Mandsager et al. Association of Cardiorespiratory Fitness With Long-term Mortality Among Adults Undergoing Exercise Treadmill Testing. JAMA Netw Open, 1(6):e183605, 2018. doi:10.1001/jamanetworkopen.2018.3605 Evidence: Low

     Verified 2026-09-26 · PMID 30646252 · DOI 10.1001/jamanetworkopen.2018.3605

     • Wiki: Exercise and longevity
     • Wiki: VO2 max
     • Wiki: Cardiovascular disease
     • What Matters: Movement: What Matters?
     • Deep dive: The 10 things that matter most for your heart
     • Deep dive: The 8 things that matter most in exercise

600. manzoli2007maritalstatus

     L. Manzoli et al. Marital status and mortality in the elderly: a systematic review and meta-analysis. Soc Sci Med, 64(1):77-94, 2007. doi:10.1016/j.socscimed.2006.08.031 Evidence: High

     Verified 2026-09-26 · PMID 17011690 · DOI 10.1016/j.socscimed.2006.08.031

     • Wiki: Social connection
     • Deep dive: The 8 things that matter most for connection and purpose
     • Quiz: Social life

601. marin2005longterm

     J. M. Marin et al. Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet, 365(9464):1046-53, 2005. doi:10.1016/S0140-6736(05)71141-7 Evidence: Low

     Verified 2026-09-26 · PMID 15781100 · DOI 10.1016/S0140-6736(05)71141-7

     • Wiki: Sleep duration and mortality
     • Wiki: Skin aging
     • What Matters: What sleep does to how long you live
     • Deep dive: The 8 things that matter most for your sleep
     • Deep dive: What your eyebags are actually telling you about your health
     • Deep dive: How sleep affects how long you live
     • Quiz: Sleep
     • What Matters: Habits that swing heart-disease death risk
     • What Matters: What raises — or cuts — stroke death risk
     • What Matters: Levers on hypertensive disease deaths
     • What Matters: The healthiest habits, ranked

602. markevych2017exploringpathways

     I. Markevych et al. Exploring pathways linking greenspace to health: Theoretical and methodological guidance. Environ Res, 158:301-317, 2017. doi:10.1016/j.envres.2017.06.028 Evidence: Not graded (review)

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     • Wiki: Green space
     • Deep dive: Does living somewhere green actually help you live longer?

603. masui2006tokyocentenarian

     Y. Masui et al. Do personality characteristics predict longevity? Findings from the Tokyo Centenarian Study. Age (Dordr), 28(4):353-61, 2006. doi:10.1007/s11357-006-9024-6 Evidence: Very low

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     • Wiki: Stress and anxiety
     • Deep dive: The 8 things that matter most for staying calm
     • Quiz: Calm check

604. mayonabagsunder

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Skin aging
     • Deep dive: What your eyebags are actually telling you about your health

605. mcdonough2022petownership

     I. M. McDonough et al. Pet ownership is associated with greater cognitive and brain health in a cross-sectional sample across the adult lifespan. Front Aging Neurosci, 14:953889, 2022. doi:10.3389/fnagi.2022.953889 Evidence: Very low

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     • Wiki: Pet ownership
     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • Deep dive: Does having a pet actually help you live longer?
     • What Matters: The healthiest habits, ranked

606. mcevoy2005mobilephones

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     • Wiki: Road safety
     • What Matters: Factors that swing accidental deaths

607. mcevoy2015smokinginflammation

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     • Wiki: Inflammation and aging
     • Deep dive: The 9 things that matter most for taming inflammation

608. mcglynn2022lncsbreplacement

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     • Deep dive: Diet soda vs regular soda vs water: what the evidence shows

609. meerwaldt2005skinautofluorescence

     R. Meerwaldt et al. Skin autofluorescence, a measure of cumulative metabolic stress and advanced glycation end products, predicts mortality in hemodialysis patients. J Am Soc Nephrol, 16(12):3687-93, 2005. doi:10.1681/asn.2005020144 Evidence: Low

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     • Wiki: Skin aging
     • Deep dive: What your skin is actually telling you about how long you live

610. mehta2018onemonth

     G. Mehta et al. Short-term abstinence from alcohol and changes in cardiovascular risk factors, liver function tests and cancer-related growth factors: a prospective observational study. BMJ Open, 8(5):e020673, 2018. doi:10.1136/bmjopen-2017-020673 Evidence: Very low

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     • Wiki: Alcohol
     • Deep dive: The 7 things to know about alcohol

611. meier2016anxietydisorders

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     • Wiki: Mental health conditions and lifespan
     • Wiki: Stress and anxiety
     • Deep dive: The mental health conditions that cost the most years, ranked
     • Quiz: Mental wellbeing

612. meigs2000parentaldiabetes

     J. B. Meigs, L. A. Cupples, and P. W. Wilson. Parental transmission of type 2 diabetes: the Framingham Offspring Study. Diabetes, 49(12):2201-7, 2000. doi:10.2337/diabetes.49.12.2201 Evidence: Low

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     • Wiki: Metabolic health and type 2 diabetes
     • Wiki: Family history and genetics
     • Deep dive: The 9 factors that decide your type 2 diabetes risk
     • What Matters: What moves diabetes death odds

613. mensink2003dietaryfats

     R. P. Mensink et al. Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials. Am J Clin Nutr, 77(5):1146-55, 2003. doi:10.1093/ajcn/77.5.1146 Evidence: High

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     • Wiki: Cholesterol
     • Deep dive: The 9 things that matter most for your cholesterol

614. merom2016dancing

     D. Merom, D. Ding, and E. Stamatakis. Dancing Participation and Cardiovascular Disease Mortality: A Pooled Analysis of 11 Population-Based British Cohorts. Am J Prev Med, 50(6):756-760, 2016. doi:10.1016/j.amepre.2016.01.004 Evidence: Low

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     • Wiki: Sports and active hobbies

615. merrick2019vitalsigns

     M. T. Merrick et al. Vital Signs: Estimated Proportion of Adult Health Problems Attributable to Adverse Childhood Experiences and Implications for Prevention - 25 States, 2015-2017. MMWR Morb Mortal Wkly Rep, 68(44):999-1005, 2019. doi:10.15585/mmwr.mm6844e1 Evidence: Very low

     Verified 2026-09-26 · PMID 31697656 · DOI 10.15585/mmwr.mm6844e1

     • Wiki: Adverse childhood experiences
     • Wiki: Mental health and relationships (section)
     • Deep dive: Adverse childhood experiences: what an ACE score predicts, and what still helps now

616. mezuk2008depressiontype

     B. Mezuk et al. Depression and type 2 diabetes over the lifespan: a meta-analysis. Diabetes Care, 31(12):2383-90, 2008. doi:10.2337/dc08-0985 Evidence: High

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     • Wiki: Mental health conditions and lifespan
     • Deep dive: What depression does to a lifespan, treated and untreated
     • What Matters: What moves diabetes death odds

617. miao2025poorsleep

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     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

618. micha2010redprocessed

     R. Micha, S. K. Wallace, and D. Mozaffarian. Red and processed meat consumption and risk of incident coronary heart disease, stroke, and diabetes mellitus: a systematic review and meta-analysis. Circulation, 121(21):2271-83, 2010. doi:10.1161/CIRCULATIONAHA.109.924977 Evidence: Moderate

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     • What Matters: Habits that swing heart-disease death risk
     • What Matters: What moves diabetes death odds

619. michaud1999fluidintake

     D. S. Michaud et al. Fluid intake and the risk of bladder cancer in men. N Engl J Med, 340(18):1390-7, 1999. doi:10.1056/NEJM199905063401803 Evidence: Low

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     • What Matters: What changes bladder cancer death risk

620. michaud2007periodontaldisease

     D. S. Michaud et al. A prospective study of periodontal disease and pancreatic cancer in US male health professionals. J Natl Cancer Inst, 99(2):171-5, 2007. doi:10.1093/jnci/djk021 Evidence: Low

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     • What Matters: What moves pancreatic cancer death risk

621. mileschan2015sugarfree

     J. L. Miles-Chan et al. The blood pressure-elevating effect of Red Bull energy drink is mimicked by caffeine but through different hemodynamic pathways. Physiol Rep, 3(2):e12290, 2015. doi:10.14814/phy2.12290 Evidence: Low

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Coffee, tea and energy drinks
     • Deep dive: The 7 things to know about coffee, tea, and energy drinks

622. mitchell2008effectexposure

     R. Mitchell and F. Popham. Effect of exposure to natural environment on health inequalities: an observational population study. Lancet, 372(9650):1655-60, 2008. doi:10.1016/S0140-6736(08)61689-X Evidence: Very low

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     • Wiki: Green space
     • Wiki: Environment and safety (section)
     • Deep dive: Does living somewhere green actually help you live longer?

623. mitchell2012sarcopeniadynapenia

     W. K. Mitchell et al. Sarcopenia, dynapenia, and the impact of advancing age on human skeletal muscle size and strength; a quantitative review. Front Physiol, 3:260, 2012. doi:10.3389/fphys.2012.00260 Evidence: Low

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     • Wiki: Muscle mass
     • Wiki: Grip strength
     • Wiki: Sarcopenia
     • Wiki: Strength and muscle (section)

624. mitri2008diabetesrisk

     J. Mitri, J. Castillo, and A. G. Pittas. Diabetes and risk of Non-Hodgkin's lymphoma: a meta-analysis of observational studies. Diabetes Care, 31(12):2391-7, 2008. doi:10.2337/dc08-1034 Evidence: Moderate

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     • What Matters: What moves blood-cancer death risk

625. moitra2021mentalsuicide

     M. Moitra et al. Estimating the risk of suicide associated with mental disorders: A systematic review and meta-regression analysis. J Psychiatr Res, 137:242-249, 2021. doi:10.1016/j.jpsychires.2021.02.053 Evidence: High

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     Metadata confirmed against the Europe PMC MEDLINE record for this PMID (NCBI E-utilities unavailable 2026-09-26). Per-disorder RRs (anxiety 4.89, bipolar 6.05, schizophrenia 5.98) are from Table 4 of the open-access full text (PMC8095367); the abstract gives only the 4.11–7.64 range.

     • What Matters: Factors linked to suicide deaths

626. mok2019activitytrajectories

     A. Mok et al. Physical activity trajectories and mortality: population based cohort study. BMJ, 365:l2323, 2019. doi:10.1136/bmj.l2323 Evidence: Low

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     • Deep dive: The 8 things that matter most in exercise

627. momma2022strengthtraining

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     Automated link-check got HTTP 429 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Exercise and longevity
     • Wiki: Resistance training
     • Wiki: Muscle mass
     • Wiki: Grip strength
     • Wiki: Cardiovascular disease
     • Wiki: Metabolic health and type 2 diabetes
     • Wiki: Exercise (section)
     • Wiki: Strength and muscle (section)
     • What Matters: Movement: What Matters?
     • Deep dive: The 10 things that matter most for your heart
     • Deep dive: The 8 things that matter most for your metabolism
     • Deep dive: The 8 things that matter most in exercise
     • Deep dive: The sports that add the most years, ranked
     • Quiz: Exercise
     • What Matters: Habits that swing heart-disease death risk

628. mons2015smokingcardiovascular

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     • Wiki: Smoking
     • What Matters: Habits that swing heart-disease death risk
     • What Matters: What raises — or cuts — stroke death risk

629. moore2012exercise

     S. C. Moore et al. Leisure time physical activity of moderate to vigorous intensity and mortality: a large pooled cohort analysis. PLoS Med, 9(11):e1001335, 2012. doi:10.1371/journal.pmed.1001335 Evidence: High

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     • Wiki: Exercise and longevity
     • Wiki: Zone 2 training
     • Quiz: Exercise
     • What Matters: What Affects Lifespan the Most
     • What Matters: The healthiest habits, ranked

630. moore2016leisuretime

     S. C. Moore et al. Association of Leisure-Time Physical Activity With Risk of 26 Types of Cancer in 1.44 Million Adults. JAMA Intern Med, 176(6):816-25, 2016. doi:10.1001/jamainternmed.2016.1548 Evidence: High

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     • What Matters: Smoking and the rest: lung cancer death risk
     • What Matters: What changes bowel cancer death risk
     • What Matters: Sun and the rest: melanoma death risk
     • What Matters: What changes bladder cancer death risk
     • What Matters: What changes breast cancer odds
     • What Matters: What raises stomach cancer death risk
     • What Matters: What moves blood-cancer death risk
     • What Matters: Factors that swing esophageal cancer deaths

631. mori2019cruciferous

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     • Wiki: Cruciferous vegetables

632. morin2015insomniadisorder

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     • Wiki: Insomnia

633. morris2015minddiet

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     • Wiki: Dementia risk factors
     • Deep dive: The 8 things to know about Alzheimer’s risk
     • Deep dive: Plants and your brain: what the vegetarian, Mediterranean and MIND studies really show about dementia

634. morris2015minddiet2

     M. C. Morris et al. MIND diet slows cognitive decline with aging. Alzheimers Dement, 11(9):1015-22, 2015. doi:10.1016/j.jalz.2015.04.011 Evidence: Low

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     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • Deep dive: Plants and your brain: what the vegetarian, Mediterranean and MIND studies really show about dementia

635. morris2018nutrientsbioactives

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     • Deep dive: Plants and your brain: what the vegetarian, Mediterranean and MIND studies really show about dementia

636. morton2018proteinsupplementation

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     • Wiki: Resistance training
     • Wiki: Muscle mass

637. morze2020chocolate

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     • Wiki: Chocolate

638. mossavar2019whiasb

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     • Deep dive: Diet soda vs regular soda vs water: what the evidence shows

639. mousavi2022eggs

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     • Wiki: Eggs
     • What Matters: Foods ranked for longevity

640. moyzis1988ttaggg

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641. mozaffarian2006fishintake

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Dietary patterns
     • Deep dive: The 8 things that matter most on your plate

642. mubanga2017dogownership

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     • Wiki: Pet ownership
     • Deep dive: Does having a pet actually help you live longer?

643. mucci2016familialcancer

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     • Deep dive: What you inherit from your family, and what you don’t
     • What Matters: What Affects Lifespan the Most

644. mullie2016milk

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     • Wiki: Milk
     • What Matters: Foods ranked for longevity

645. murphy2024mortality2023

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     Cited for 2023 US deaths by leading cause: 3,090,964 total; heart disease 680,981, cancer 613,352, stroke 162,639, Alzheimer disease 114,034, diabetes 95,190. These set the cause shares f in the family-history outcome-fraction bridges.

     • Deep dive: What you inherit from your family, and what you don’t
     • What Matters: What Affects Lifespan the Most

646. myers2015benefitsharms

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     • What Matters: What changes breast cancer odds

647. myung2025collagensupplement

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     • Wiki: Skin aging
     • Deep dive: What your skin is actually telling you about how long you live

648. nachvak2019soy

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     • Wiki: Soy foods

649. naghshi2022dairyfat

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     • Wiki: Milk

650. namazi2018soy

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     • Wiki: Soy foods

651. nanni2012childhoodmaltreatment

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     • Wiki: Adverse childhood experiences
     • Deep dive: Adverse childhood experiences: what an ACE score predicts, and what still helps now

652. naomi2023lifelines

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     • Wiki: Fruit juice

653. naska2007siesta

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Smoking
     • Deep dive: Smoking takes about ten years. Here is what quitting gives back
     • What Matters: Smoking and the rest: lung cancer death risk

655. nationalnacancerstat

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     • Wiki: Skin aging
     • Deep dive: What your skin is actually telling you about how long you live
     • Quiz: Skin health

656. nationalnageneticscancer

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     • Wiki: Family history and genetics
     • Deep dive: What you inherit from your family, and what you don’t

657. nationalnaquickstatistics

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     • Wiki: Hearing and vision loss
     • Deep dive: Are your ears and eyes quietly aging your brain?

658. nature2025natureexposure

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     • What Matters: What stretches, or shreds, attention

659. navarrogonzalez2023increasedmri

     R. Navarro-González et al. Increased MRI-based Brain Age in chronic migraine patients. J Headache Pain, 24(1):133, 2023. doi:10.1186/s10194-023-01670-6 Evidence: Very low

     Verified 2026-09-26 · PMID 37798720 · DOI 10.1186/s10194-023-01670-6

     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years

660. ncdrisc2021hypertension

     NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants. Lancet, 398(10304):957-980, 2021. doi:10.1016/S0140-6736(21)01330-1 Evidence: High

     Verified 2026-09-29 · PMID 34450083 · DOI 10.1016/S0140-6736(21)01330-1

     • Wiki: Blood pressure
     • Wiki: Heart and metabolic health (section)

661. nchsfastats2024unintentional

     National Center for Health Statistics. FastStats: Accidents or Unintentional Injuries. CDC National Center for Health Statistics, 2024. Evidence: Not graded (statistics)

     Verified 2026-09-26

     Mortality figures are 2024 National Vital Statistics System data via CDC WONDER: 197,449 unintentional injury deaths, 48,308 unintentional falls, 75,761 unintentional poisonings. Continuously updated page; figures read on the date verified.

     • What Matters: Factors that swing accidental deaths

662. nci2023adulttobaccouse

     National Cancer Institute. Adult tobacco use (Cancer Trends Progress Report). National Cancer Institute. Evidence: Not graded (statistics)

     Verified 2026-09-26

     Continuously updated NHIS summary. Cited for 2023 adult current cigarette smoking: 11.0%, of which 8.0% daily and 3.0% non-daily.

     • What Matters: Your estimated chance of each cause (method)

663. nci2024cancergenetics

     National Cancer Institute. Cancer Genetics Risk Assessment and Counseling (PDQ). NCI PDQ, 2024. Evidence: Not graded (reference page)

     Verified 2026-09-26

     Replaces the prior unlinked label "NCI — hereditary patterns" for the family-cancer factor.

     • Family: Cancer in the family

664. neal2021saltsubstitute

     B. Neal et al. Effect of Salt Substitution on Cardiovascular Events and Death. N Engl J Med, 385(12):1067-1077, 2021. doi:10.1056/NEJMoa2105675 Evidence: Moderate

     Verified 2026-09-26 · PMID 34459569 · DOI 10.1056/NEJMoa2105675

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Dietary patterns
     • Wiki: Blood pressure
     • Deep dive: The 8 things that matter most on your plate
     • Deep dive: Is your blood pressure quietly aging you? The 9 things that matter most

665. neter2003weightloss

     J. E. Neter et al. Influence of weight reduction on blood pressure: a meta-analysis of randomized controlled trials. Hypertension, 42(5):878-84, 2003. doi:10.1161/01.HYP.0000094221.86888.AE Evidence: High

     Verified 2026-09-26 · PMID 12975389 · DOI 10.1161/01.HYP.0000094221.86888.AE

     • Wiki: Blood pressure
     • Wiki: Heart and metabolic health (section)
     • Deep dive: Is your blood pressure quietly aging you? The 9 things that matter most

666. ngandu2015fingerlifestyle

     T. Ngandu et al. A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial. Lancet, 385(9984):2255-63, 2015. doi:10.1016/S0140-6736(15)60461-5 Evidence: Moderate

     Verified 2026-09-26 · PMID 25771249 · DOI 10.1016/S0140-6736(15)60461-5

     • Wiki: Dementia risk factors
     • Wiki: Family history and genetics
     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • Deep dive: What you inherit from your family, and what you don’t

667. nhsnahairloss

     NHS. Hair loss. NHS. Evidence: Not graded (reference page)

     Verified 2026-09-27

     Continuously-updated patient resource page, no single publication year stated.

     • Wiki: Hair loss
     • Deep dive: The 9 things balding is actually telling you about your health

668. nhtsa2022bicyclists

     National Highway Traffic Safety Administration. Traffic Safety Facts, 2022 Data: Bicyclists and Other Cyclists. NHTSA, 2024. Evidence: Not graded (statistics)

     Verified 2026-09-26

     Cited for 1,105 pedalcyclist deaths on US roads in 2022 (2.6% of traffic deaths).

     • What Matters: Your estimated chance of each cause (method)

669. nhtsa2023seatbelts

     National Highway Traffic Safety Administration. Seat Belts Save Lives. NHTSA, 2023. Evidence: Not graded (statistics)

     Verified 2026-09-26

     PR #589 confirmed this is the specific stat page (not a homepage); automated re-fetch here got a 403 (bot-block), consistent with a real, working government page.

     • Quiz: Safety habits
     • What Matters: What Affects Lifespan the Most
     • What Matters: The healthiest habits, ranked

670. nhtsanadrunkdriving

     NHTSA. Drunk Driving. NHTSA. Evidence: Not graded (statistics)

     Verified 2026-09-26

     Continuously-updated agency topic page, no single publication year stated. Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Road safety
     • Deep dive: The 9 things that matter most for surviving the road

671. nhtsanamotorcycles

     National Highway Traffic Safety Administration. Motorcycle Safety. National Highway Traffic Safety Administration (NHTSA). Evidence: Not graded (statistics)

     Verified 2026-09-27

     Continuously-updated agency topic page, no single publication year stated.

     • Wiki: Road safety
     • Deep dive: The 9 things that matter most for surviving the road

672. nhtsanaseatbelts

     National Highway Traffic Safety Administration. Seat Belts. National Highway Traffic Safety Administration (NHTSA). Evidence: Not graded (statistics)

     Verified 2026-09-27

     Continuously-updated agency topic page, no single publication year stated.

     • Wiki: Road safety
     • Wiki: Environment and safety (section)
     • Deep dive: The 9 things that matter most for surviving the road

673. nhtsanaspeeding

     National Highway Traffic Safety Administration. Speeding. National Highway Traffic Safety Administration (NHTSA). Evidence: Not graded (statistics)

     Verified 2026-09-27

     Continuously-updated agency topic page, no single publication year stated.

     • Wiki: Road safety
     • Deep dive: The 9 things that matter most for surviving the road

674. nia2024alzheimersgeneticsUNRESOLVED

     National Institute on Aging. Alzheimer's Disease Genetics Fact Sheet. NIA, 2024.* Evidence: Not graded (reference page)

     Verified 2026-09-26

     Replaces the prior unlinked label "NCI — hereditary patterns" for the family-dementia factor (NCI does not cover dementia; NIA is the right agency). The page itself returns a bot-block (405/"Human Verification") to automated fetches in this session, so the URL could not be confirmed by opening it — flagging as unresolved rather than asserting it resolves.

     • Family: Dementia in the family

675. niaaa2023alcoholoverdose

     National Institute on Alcohol Abuse and Alcoholism. Understanding the Dangers of Alcohol Overdose. NIAAA. Evidence: Not graded (reference page)

     Verified 2026-09-27

     Cited for the liver clearing roughly one standard drink an hour.

     • What Matters: Your estimated chance of each cause (method)

676. nice2018posttraumatic

     National Institute for Health and Care Excellence. Post-traumatic stress disorder. National Institute for Health and Care Excellence (NICE guideline NG116), 2018. Evidence: Not graded (guideline)

     Verified 2026-09-27

     • Wiki: Adverse childhood experiences
     • Deep dive: Adverse childhood experiences: what an ACE score predicts, and what still helps now

677. nice2025ng246

     National Institute for Health and Care Excellence. Overweight and obesity management: identifying and assessing overweight, obesity and central adiposity. National Institute for Health and Care Excellence (NICE guideline NG246), 2025. Evidence: Not graded (guideline)

     Verified 2026-09-30

     Recommendations 1.9.14 and 1.9.15 (waist-to-height ratio 0.4 to 0.49 healthy; keep your waist under half your height) date from the 2022 CG189 update, which NG246 replaced in 2025.

     • Deep dive: Body Check: five at-home tests linked to how long you live

678. nichols2024designlife

     E. S. Nichols et al. A design for life: Predicting cognitive performance from lifestyle choices. PLoS One, 19(4):e0298899, 2024. doi:10.1371/journal.pone.0298899 Evidence: Very low

     Verified 2026-09-26 · PMID 38626013 · DOI 10.1371/journal.pone.0298899

     • Wiki: Cognitive aging
     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

679. nicholson2006depressioncoronary

     A. Nicholson, H. Kuper, and H. Hemingway. Depression as an aetiologic and prognostic factor in coronary heart disease: a meta-analysis of 6362 events among 146 538 participants in 54 observational studies. Eur Heart J, 27(23):2763-74, 2006. doi:10.1093/eurheartj/ehl338 Evidence: Low

     Verified 2026-09-27 · PMID 17082208 · DOI 10.1093/eurheartj/ehl338

     • Wiki: Mental health conditions and lifespan
     • Deep dive: What depression does to a lifespan, treated and untreated
     • What Matters: Habits that swing heart-disease death risk

680. nidorf2020lodoco2

     S. M. Nidorf et al. Colchicine in Patients with Chronic Coronary Disease. N Engl J Med, 383(19):1838-1847, 2020. doi:10.1056/NEJMoa2021372 Evidence: Moderate

     Verified 2026-09-28 · PMID 32865380 · DOI 10.1056/NEJMoa2021372

     • Wiki: Inflammation and aging

681. niiranen2017riskhypertension

     T. J. Niiranen et al. Risk for hypertension crosses generations in the community: a multi-generational cohort study. Eur Heart J, 38(29):2300-2308, 2017. doi:10.1093/eurheartj/ehx134 Evidence: Low

     Verified 2026-09-26 · PMID 28430902 · DOI 10.1093/eurheartj/ehx134

     • What Matters: Levers on hypertensive disease deaths

682. ning2020associationrelative

     K. Ning et al. Association of relative brain age with tobacco smoking, alcohol consumption, and genetic variants. Sci Rep, 10(1):10, 2020. doi:10.1038/s41598-019-56089-4 Evidence: Very low

     Verified 2026-09-26 · PMID 32001736 · DOI 10.1038/s41598-019-56089-4

     • Wiki: Cognitive aging
     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

683. nishihara2013longterm

     R. Nishihara et al. Long-term colorectal-cancer incidence and mortality after lower endoscopy. N Engl J Med, 369(12):1095-105, 2013. doi:10.1056/NEJMoa1301969 Evidence: Moderate

     Verified 2026-09-26 · PMID 24047059 · DOI 10.1056/NEJMoa1301969

     • What Matters: What changes bowel cancer death risk

684. nobre2008ltheanine

     A. C. Nobre, A. Rao, and G. N. Owen. L-theanine, a natural constituent in tea, and its effect on mental state. Asia Pac J Clin Nutr, 17 Suppl 1:167-168, 2008. Evidence: Very low

     Verified 2026-09-28 · PMID 18296328

     No DOI in PubMed (supplement abstract); the supplement has no issue number.

     • Wiki: L-theanine (supplement)

685. nocon2008physicalactivity

     M. Nocon et al. Association of physical activity with all-cause and cardiovascular mortality: a systematic review and meta-analysis. Eur J Cardiovasc Prev Rehabil, 15(3):239-46, 2008. doi:10.1097/HJR.0b013e3282f55e09 Evidence: High

     Verified 2026-09-26 · PMID 18525377 · DOI 10.1097/HJR.0b013e3282f55e09

     • What Matters: Habits that swing heart-disease death risk

686. noetel2024exercisedepression

     M. Noetel et al. Effect of exercise for depression: systematic review and network meta-analysis of randomised controlled trials. BMJ, 384:e075847, 2024. doi:10.1136/bmj-2023-075847 Evidence: Low

     Verified 2026-09-26 · PMID 38355154 · DOI 10.1136/bmj-2023-075847

     • Wiki: Mental health conditions and lifespan
     • Wiki: Stress and anxiety
     • Deep dive: The mental health conditions that cost the most years, ranked
     • Deep dive: What depression does to a lifespan, treated and untreated

687. nordestgaard2013familial

     B. G. Nordestgaard et al. Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of the European Atherosclerosis Society. Eur Heart J, 34(45):3478-90a, 2013. doi:10.1093/eurheartj/eht273 Evidence: Not graded (guideline)

     Verified 2026-09-28 · PMID 23956253 · DOI 10.1093/eurheartj/eht273

     European Atherosclerosis Society consensus statement; left untiered.

     • Wiki: Cholesterol
     • Wiki: Family history and genetics
     • Quiz: Cholesterol check

688. noseworthy2025biologicalsex

     M. Noseworthy et al. Investigating biological sex as a moderator of the association of nature exposure with brain health: a cross-sectional UK biobank analysis. Sci Rep, 15(1):21063, 2025. doi:10.1038/s41598-025-05047-4 Evidence: Very low

     Verified 2026-09-26 · PMID 40594321 · DOI 10.1038/s41598-025-05047-4

     • Deep dive: How to lower your cognitive age: every habit with a number in years

689. o2010physicalactivity

     M. A. O'Rorke et al. Can physical activity modulate pancreatic cancer risk? a systematic review and meta-analysis. Int J Cancer, 126(12):2957-68, 2010. doi:10.1002/ijc.24997 Evidence: Low

     Verified 2026-09-26 · PMID 19856317 · DOI 10.1002/ijc.24997

     • What Matters: What moves pancreatic cancer death risk

690. o2017weekendwarrior

     G. O'Donovan et al. Association of "Weekend Warrior" and Other Leisure Time Physical Activity Patterns With Risks for All-Cause, Cardiovascular Disease, and Cancer Mortality. JAMA Intern Med, 177(3):335-342, 2017. doi:10.1001/jamainternmed.2016.8014 Evidence: Moderate

     Verified 2026-09-26 · PMID 28097313 · DOI 10.1001/jamainternmed.2016.8014

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Exercise and longevity
     • What Matters: Movement: What Matters?
     • Deep dive: The 8 things that matter most in exercise

691. o2025lifeexpectancy

     E. O'Nions et al. Life expectancy and years of life lost for adults with diagnosed ADHD in the UK: matched cohort study. Br J Psychiatry, 226(5):261-268, 2025. doi:10.1192/bjp.2024.199 Evidence: Low

     Verified 2026-09-26 · PMID 39844532 · DOI 10.1192/bjp.2024.199

     • Wiki: Mental health conditions and lifespan
     • Deep dive: The mental health conditions that cost the most years, ranked

692. obayashi2014bedroomlight

     K. Obayashi, K. Saeki, and N. Kurumatani. Association between light exposure at night and insomnia in the general elderly population: the HEIJO-KYO cohort. Chronobiol Int, 31(9):976-82, 2014. doi:10.3109/07420528.2014.937491 Evidence: Very low

     Verified 2026-09-26 · PMID 25025617 · DOI 10.3109/07420528.2014.937491

     • Wiki: Sleep quality
     • What Matters: What actually moves sleep quality
     • Deep dive: What matters most for high-quality sleep
     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

693. office2024officetemperature

     X. Lin et al. The effects of temperature on work performance in the typical office environment: A meta-analysis of the current evidence. Build Environ, 269:112488, 2024. doi:10.1016/j.buildenv.2024.112488 Evidence: Not graded (design not checkable)

     Verified 2026-09-26 · DOI 10.1016/j.buildenv.2024.112488

     • What Matters: What stretches, or shreds, attention

694. oforiasenso2021chilli

     R. Ofori-Asenso et al. Association of Spicy Chilli Food Consumption With Cardiovascular and All-Cause Mortality: A Meta-Analysis of Prospective Cohort Studies. Angiology, 72(7):625-632, 2021. doi:10.1177/0003319721995666 Evidence: Moderate

     Verified 2026-10-01 · PMID 33657876 · DOI 10.1177/0003319721995666

     • Wiki: Chili peppers
     • What Matters: Foods ranked for longevity

695. ogechi2016petownership

     I. Ogechi et al. Pet Ownership and the Risk of Dying from Cardiovascular Disease Among Adults Without Major Chronic Medical Conditions. High Blood Pressure & Cardiovascular Prevention, 23(3):245-53, 2016. doi:10.1007/s40292-016-0156-1 Evidence: Low

     Verified 2026-09-27 · PMID 27174431 · DOI 10.1007/s40292-016-0156-1

     • Wiki: Pet ownership
     • Deep dive: Does having a pet actually help you live longer?

696. ohayon2002insomniaepidemiology

     M. M. Ohayon. Epidemiology of insomnia: what we know and what we still need to learn. Sleep Med Rev, 6(2):97-111, 2002. doi:10.1053/smrv.2002.0186 Evidence: Very low

     Verified 2026-09-28 · PMID 12531146 · DOI 10.1053/smrv.2002.0186

     • Wiki: Insomnia
     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

697. ohayon2017nsfsleepquality

     M. Ohayon et al. National Sleep Foundation's sleep quality recommendations: first report. Sleep Health, 3(1):6-19, 2017. doi:10.1016/j.sleh.2016.11.006 Evidence: Not graded (guideline)

     Verified 2026-09-29 · PMID 28346153 · DOI 10.1016/j.sleh.2016.11.006

     Expert consensus (modified Delphi RAND/UCLA method) informed by a systematic review of 277 studies; a recommendation statement, so left untiered per §3.

     • Wiki: Sleep quality
     • Wiki: Naps

698. ohly2016attentionrestoration

     H. Ohly et al. Attention Restoration Theory: A systematic review of the attention restoration potential of exposure to natural environments. J Toxicol Environ Health B Crit Rev, 19(7):305-343, 2016. doi:10.1080/10937404.2016.1196155 Evidence: Low

     Verified 2026-09-26 · PMID 27668460 · DOI 10.1080/10937404.2016.1196155

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • What Matters: What stretches, or shreds, attention

699. oja2017sportdisciplines

     P. Oja et al. Associations of specific types of sports and exercise with all-cause and cardiovascular-disease mortality: a cohort study of 80 306 British adults. Br J Sports Med, 51(10):812-817, 2017. doi:10.1136/bjsports-2016-096822 Evidence: Low

     Verified 2026-09-26 · PMID 27895075 · DOI 10.1136/bjsports-2016-096822

     • Wiki: Sports and active hobbies
     • Wiki: Everyday movement (section)
     • Deep dive: The sports that add the most years, ranked

700. okun2013volunteeringmortality

     M. A. Okun, E. W. Yeung, and S. Brown. Volunteering by older adults and risk of mortality: a meta-analysis. Psychol Aging, 28(2):564-77, 2013. doi:10.1037/a0031519 Evidence: Moderate

     Verified 2026-09-26 · PMID 23421326 · DOI 10.1037/a0031519

     • Wiki: Social connection
     • Deep dive: The 8 things that matter most for connection and purpose

701. olivier2017bicyclehelmet

     J. Olivier and P. Creighton. Bicycle injuries and helmet use: a systematic review and meta-analysis. Int J Epidemiol, 46(1):278-292, 2017. doi:10.1093/ije/dyw153 Evidence: High

     Verified 2026-09-26 · PMID 27450862 · DOI 10.1093/ije/dyw153

     • Wiki: Road safety
     • Deep dive: The 9 things that matter most for surviving the road
     • Quiz: Safety habits
     • What Matters: Factors that swing accidental deaths

702. olovnikov1973marginotomy

     A. M. Olovnikov. A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon. J Theor Biol, 41(1):181-90, 1973. doi:10.1016/0022-5193(73)90198-7 Evidence: Not graded (design not checkable)

     Verified 2026-09-28 · PMID 4754905 · DOI 10.1016/0022-5193(73)90198-7

     Untiered: PubMed has no abstract for this 1973 theoretical paper, so its design cannot be graded against §3.

     • Wiki: Telomeres

703. olsen20025vs

     E. A. Olsen et al. A randomized clinical trial of 5% topical minoxidil versus 2% topical minoxidil and placebo in the treatment of androgenetic alopecia in men. J Am Acad Dermatol, 47(3):377-85, 2002. doi:10.1067/mjd.2002.124088 Evidence: Moderate

     Verified 2026-09-26 · PMID 12196747 · DOI 10.1067/mjd.2002.124088

     • Wiki: Hair loss
     • Deep dive: The 9 things balding is actually telling you about your health

704. onainterstrokelancet

     M. J. O'Donnell et al. Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study. Lancet, 376(9735):112-23, 2010. doi:10.1016/S0140-6736(10)60834-3 Evidence: Moderate

     Verified 2026-09-26 · PMID 20561675 · DOI 10.1016/S0140-6736(10)60834-3

     • What Matters: What raises — or cuts — stroke death risk

705. ong2014mindfulnessinsomnia

     J. C. Ong et al. A randomized controlled trial of mindfulness meditation for chronic insomnia. Sleep, 37(9):1553-63, 2014. doi:10.5665/sleep.4010 Evidence: Low

     Verified 2026-10-08 · PMID 25142566 · DOI 10.5665/sleep.4010

     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

706. onni2025umbrella

     A. T. Onni et al. Umbrella Review of Systematic Reviews and Meta-analyses on Consumption of Different Food Groups and Risk of All-cause Mortality. Adv Nutr, 16(4):100393, 2025. doi:10.1016/j.advnut.2025.100393 Evidence: Moderate

     Verified 2026-10-01 · PMID 39956388 · DOI 10.1016/j.advnut.2025.100393

     • Wiki: Legumes
     • Wiki: Refined grains

707. orlich2013vegetariandietary

     M. J. Orlich et al. Vegetarian dietary patterns and mortality in Adventist Health Study 2. JAMA Intern Med, 173(13):1230-8, 2013. doi:10.1001/jamainternmed.2013.6473 Evidence: Low

     Verified 2026-09-26 · PMID 23836264 · DOI 10.1001/jamainternmed.2013.6473

     • Wiki: Dietary patterns
     • Deep dive: Vegan, vegetarian, omnivore, carnivore: what the labels actually buy you
     • Quiz: Diet

708. orlich2015vegetariandietary

     M. J. Orlich et al. Vegetarian dietary patterns and the risk of colorectal cancers. JAMA Intern Med, 175(5):767-76, 2015. doi:10.1001/jamainternmed.2015.59 Evidence: Low

     Verified 2026-09-26 · PMID 25751512 · DOI 10.1001/jamainternmed.2015.59

     • What Matters: What changes bowel cancer death risk

709. osimo2019lowgrade

     E. F. Osimo et al. Prevalence of low-grade inflammation in depression: a systematic review and meta-analysis of CRP levels. Psychol Med, 49(12):1958-1970, 2019. doi:10.1017/S0033291719001454 Evidence: Low

     Verified 2026-09-26 · PMID 31258105 · DOI 10.1017/S0033291719001454

     • Wiki: Inflammation and aging
     • Deep dive: The 9 things that matter most for taming inflammation

710. owsley2002cataractcrash

     C. Owsley et al. Impact of cataract surgery on motor vehicle crash involvement by older adults. JAMA, 288(7):841-9, 2002. doi:10.1001/jama.288.7.841 Evidence: Low

     Verified 2026-09-26 · PMID 12186601 · DOI 10.1001/jama.288.7.841

     • Wiki: Hearing and vision loss
     • What Matters: Factors that swing accidental deaths

711. pacheco2022avocado

     L. S. Pacheco et al. Avocado Consumption and Risk of Cardiovascular Disease in US Adults. J Am Heart Assoc, 11(7):e024014, 2022. doi:10.1161/JAHA.121.024014 Evidence: Low

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     • Wiki: Avocado

712. paleczny2025characterizingcognitive

     S. G. Paleczny et al. Characterizing the cognitive and mental health benefits of exercise and video game playing. PLoS One, 20(10):e0334924, 2025. doi:10.1371/journal.pone.0334924 Evidence: Very low

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     • Wiki: Cognitive aging
     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

713. palomarcros2023dietarycircadian

     A. Palomar-Cros et al. Dietary circadian rhythms and cardiovascular disease risk in the prospective NutriNet-Santé cohort. Nat Commun, 14(1):7899, 2023. doi:10.1038/s41467-023-43444-3 Evidence: Low

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     • Wiki: Meal timing
     • Deep dive: Does an early last meal actually help you live longer?

714. paluch2022dailysteps

     A. E. Paluch et al. Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts. Lancet Public Health, 7(3):e219-e228, 2022. doi:10.1016/S2468-2667(21)00302-9 Evidence: High

     Verified 2026-09-26 · PMID 35247352 · DOI 10.1016/S2468-2667(21)00302-9

     • Wiki: Exercise and longevity
     • Wiki: Walking and daily steps
     • Wiki: Exercise (section)
     • Wiki: Cardio and aerobic fitness (section)
     • What Matters: Movement: What Matters?
     • Deep dive: The 10 things that matter most for your heart

715. pan2011depressionrisk

     A. Pan et al. Depression and risk of stroke morbidity and mortality: a meta-analysis and systematic review. JAMA, 306(11):1241-9, 2011. doi:10.1001/jama.2011.1282 Evidence: High

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     • Wiki: Mental health conditions and lifespan
     • Deep dive: What depression does to a lifespan, treated and untreated
     • What Matters: What raises — or cuts — stroke death risk

716. pan2015activepassive

     A. Pan et al. Relation of active, passive, and quitting smoking with incident type 2 diabetes: a systematic review and meta-analysis. Lancet Diabetes Endocrinol, 3(12):958-67, 2015. doi:10.1016/S2213-8587(15)00316-2 Evidence: High

     Verified 2026-09-26 · PMID 26388413 · DOI 10.1016/S2213-8587(15)00316-2

     • Wiki: Smoking
     • Wiki: Metabolic health and type 2 diabetes
     • What Matters: What moves diabetes death odds

717. pan2022softdrinkjuice

     B. Pan et al. Association of soft drink and 100% fruit juice consumption with all-cause mortality, cardiovascular diseases mortality, and cancer mortality: A systematic review and dose-response meta-analysis of prospective cohort studies. Crit Rev Food Sci Nutr, 62(32):8908-8919, 2022. doi:10.1080/10408398.2021.1937040 Evidence: Moderate

     Verified 2026-10-01 · PMID 34121531 · DOI 10.1080/10408398.2021.1937040

     • Wiki: Fruit juice

718. papp2023poultry

     R. E. Papp et al. Association of poultry consumption with cardiovascular diseases and all-cause mortality: a systematic review and dose response meta-analysis of prospective cohort studies. Crit Rev Food Sci Nutr, 63(15):2366-2387, 2023. doi:10.1080/10408398.2021.1975092 Evidence: Moderate

     Verified 2026-10-01 · PMID 34542332 · DOI 10.1080/10408398.2021.1975092

     • Wiki: Poultry
     • What Matters: Foods ranked for longevity

719. park2025globallifetime

     J. Y. Park et al. Global lifetime estimates of expected and preventable gastric cancers across 185 countries. Nat Med, 31(9):3020-3027, 2025. doi:10.1038/s41591-025-03793-6 Evidence: Moderate

     Verified 2026-10-04 · PMID 40624406 · DOI 10.1038/s41591-025-03793-6

     • Wiki: Helicobacter pylori
     • Deep dive: H. pylori and stomach cancer: what the evidence shows

720. parker2022allostaticload

     H. W. Parker et al. Allostatic Load and Mortality: A Systematic Review and Meta-Analysis. Am J Prev Med, 63(1):131-140, 2022. doi:10.1016/j.amepre.2022.02.003 Evidence: Moderate

     Verified 2026-09-27 · PMID 35393143 · DOI 10.1016/j.amepre.2022.02.003

     • Wiki: Stress and anxiety
     • Deep dive: The 8 things that matter most for staying calm
     • Quiz: Calm check

721. parsaik2016sleepingpills

     A. K. Parsaik et al. Mortality associated with anxiolytic and hypnotic drugs-A systematic review and meta-analysis. Aust N Z J Psychiatry, 50(6):520-33, 2016. doi:10.1177/0004867415616695 Evidence: Moderate

     Verified 2026-09-26 · PMID 26590022 · DOI 10.1177/0004867415616695

     • Wiki: Insomnia
     • Wiki: Sleep duration and mortality
     • What Matters: What sleep does to how long you live
     • Deep dive: How sleep affects how long you live
     • Deep dive: Top 10 insomnia remedies, ranked by the evidence
     • What Matters: The healthiest habits, ranked

722. pase2017asbstroke

     M. P. Pase et al. Sugar- and Artificially Sweetened Beverages and the Risks of Incident Stroke and Dementia: A Prospective Cohort Study. Stroke, 48(5):1139-1146, 2017. doi:10.1161/STROKEAHA.116.016027 Evidence: Low

     Verified 2026-10-05 · PMID 28428346 · DOI 10.1161/STROKEAHA.116.016027

     • Deep dive: Diet soda vs regular soda vs water: what the evidence shows

723. pase2017sugarybeverage

     M. P. Pase et al. Sugary beverage intake and preclinical Alzheimer's disease in the community. Alzheimers Dement, 13(9):955-964, 2017. doi:10.1016/j.jalz.2017.01.024 Evidence: Very low

     Verified 2026-09-26 · PMID 28274718 · DOI 10.1016/j.jalz.2017.01.024

     • Wiki: Cognitive aging
     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

724. patel2012sleeppneumonia

     S. R. Patel et al. A prospective study of sleep duration and pneumonia risk in women. Sleep, 35(1):97-101, 2012. doi:10.5665/sleep.1594 Evidence: Low

     Verified 2026-09-26 · PMID 22215923 · DOI 10.5665/sleep.1594

     Nurses' Health Study II, women aged 37-57 only; observational.

     • What Matters: Factors that swing flu and pneumonia deaths

725. patel2017dogbed

     S. I. Patel et al. The Effect of Dogs on Human Sleep in the Home Sleep Environment. Mayo Clin Proc, 92(9):1368-1372, 2017. doi:10.1016/j.mayocp.2017.06.014 Evidence: Very low

     Verified 2026-09-26 · PMID 28870354 · DOI 10.1016/j.mayocp.2017.06.014

     • What Matters: What actually moves sleep quality
     • Deep dive: What matters most for high-quality sleep
     • What Matters: The healthiest habits, ranked

726. pavasini2016sppb

     R. Pavasini et al. Short Physical Performance Battery and all-cause mortality: systematic review and meta-analysis. BMC Med, 14(1):215, 2016. doi:10.1186/s12916-016-0763-7 Evidence: High

     Verified 2026-09-28 · PMID 28003033 · DOI 10.1186/s12916-016-0763-7

     • Wiki: Functional fitness

727. pawlak2013howprevalent

     R. Pawlak et al. How prevalent is vitamin B(12) deficiency among vegetarians?. Nutr Rev, 71(2):110-7, 2013. doi:10.1111/nure.12001 Evidence: Not graded (review)

     Verified 2026-09-26 · PMID 23356638 · DOI 10.1111/nure.12001

     • Wiki: Dietary patterns
     • Deep dive: Vegan, vegetarian, omnivore, carnivore: what the labels actually buy you
     • Deep dive: Plants and your brain: what the vegetarian, Mediterranean and MIND studies really show about dementia

728. paz2023isthere

     V. Paz, H. S. Dashti, and V. Garfield. Is there an association between daytime napping, cognitive function, and brain volume? A Mendelian randomization study in the UK Biobank. Sleep Health, 9(5):786-793, 2023. doi:10.1016/j.sleh.2023.05.002 Evidence: Low

     Verified 2026-09-26 · PMID 37344293 · DOI 10.1016/j.sleh.2023.05.002

     • Wiki: Naps
     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • Deep dive: Do naps make your brain younger, or are long ones a red flag?
     • What Matters: The healthiest habits, ranked

729. pearcenaocaclancet

     C. L. Pearce et al. Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case-control studies. Lancet Oncol, 13(4):385-94, 2012. doi:10.1016/S1470-2045(11)70404-1 Evidence: Moderate

     Verified 2026-09-26 · PMID 22361336 · DOI 10.1016/S1470-2045(11)70404-1

     • What Matters: What raises ovarian cancer death risk

730. pega2021longworking

     F. Pega et al. Global, regional, and national burdens of ischemic heart disease and stroke attributable to exposure to long working hours for 194 countries, 2000-2016: A systematic analysis from the WHO/ILO Joint Estimates of the Work-related Burden of Disease and Injury. Environ Int, 154:106595, 2021. doi:10.1016/j.envint.2021.106595 Evidence: Not graded (statistics)

     Verified 2026-09-27 · PMID 34011457 · DOI 10.1016/j.envint.2021.106595

     • Wiki: Stress and anxiety
     • Deep dive: The 8 things that matter most for staying calm
     • Quiz: Stress

731. penninx2013biologicalmechanisms

     B. W. Penninx et al. Understanding the somatic consequences of depression: biological mechanisms and the role of depression symptom profile. BMC Med, 11:129, 2013. doi:10.1186/1741-7015-11-129 Evidence: Very low

     Verified 2026-09-26 · PMID 23672628 · DOI 10.1186/1741-7015-11-129

     • Wiki: Mental health conditions and lifespan
     • Deep dive: What depression does to a lifespan, treated and untreated

732. peppard2013osaprevalence

     P. E. Peppard et al. Increased prevalence of sleep-disordered breathing in adults. Am J Epidemiol, 177(9):1006-14, 2013. doi:10.1093/aje/kws342 Evidence: Very low

     Verified 2026-09-22 · PMID 23589584 · DOI 10.1093/aje/kws342

     • Wiki: Insomnia

733. perezcornago2017tallheight

     A. Perez-Cornago et al. Tall height and obesity are associated with an increased risk of aggressive prostate cancer: results from the EPIC cohort study. BMC Med, 15(1):115, 2017. doi:10.1186/s12916-017-0876-7 Evidence: Moderate

     Verified 2026-09-27 · PMID 28701188 · DOI 10.1186/s12916-017-0876-7

     • What Matters: Levers on prostate cancer death risk

734. pescador2024midliferesidential

     M. Pescador Jimenez et al. Midlife Residential Greenness and Late-Life Cognitive Decline among Nurses' Health Study Participants. Environ Health Perspect, 132(7):77003, 2024. doi:10.1289/EHP13588 Evidence: Low

     Verified 2026-09-26 · PMID 39016600 · DOI 10.1289/EHP13588

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Deep dive: How to lower your cognitive age: every habit with a number in years

735. peters2016nnswater

     J. C. Peters et al. The effects of water and non-nutritive sweetened beverages on weight loss and weight maintenance: A randomized clinical trial. Obesity (Silver Spring), 24(2):297-304, 2016. doi:10.1002/oby.21327 Evidence: Moderate

     Verified 2026-10-05 · PMID 26708700 · DOI 10.1002/oby.21327

     • Deep dive: Diet soda vs regular soda vs water: what the evidence shows

736. peterson2010resistancestrength

     M. D. Peterson et al. Resistance exercise for muscular strength in older adults: a meta-analysis. Ageing Res Rev, 9(3):226-237, 2010. doi:10.1016/j.arr.2010.03.004 Evidence: Moderate

     Verified 2026-09-28 · PMID 20385254 · DOI 10.1016/j.arr.2010.03.004

     • Wiki: Resistance training
     • Wiki: Grip strength
     • Wiki: Sarcopenia

737. peterson2011resistanceleanmass

     M. D. Peterson, A. Sen, and P. M. Gordon. Influence of resistance exercise on lean body mass in aging adults: a meta-analysis. Med Sci Sports Exerc, 43(2):249-258, 2011. doi:10.1249/MSS.0b013e3181eb6265 Evidence: Moderate

     Verified 2026-09-28 · PMID 20543750 · DOI 10.1249/MSS.0b013e3181eb6265

     • Wiki: Resistance training
     • Wiki: Muscle mass
     • Wiki: Sarcopenia
     • Wiki: Strength and muscle (section)

738. peto2000smokingsmoking

     R. Peto et al. Smoking, smoking cessation, and lung cancer in the UK since 1950: combination of national statistics with two case-control studies. BMJ, 321(7257):323-9, 2000. doi:10.1136/bmj.321.7257.323 Evidence: Low

     Verified 2026-09-26 · PMID 10926586 · DOI 10.1136/bmj.321.7257.323

     • Wiki: Smoking
     • What Matters: Smoking and the rest: lung cancer death risk

739. phung2013bmipneumonia

     D. T. Phung et al. Body mass index and risk of pneumonia: a systematic review and meta-analysis. Obes Rev, 14(10):839-57, 2013. doi:10.1111/obr.12055 Evidence: High

     Verified 2026-09-26 · PMID 23800284 · DOI 10.1111/obr.12055

     • What Matters: Factors that swing flu and pneumonia deaths

740. pimpin2016butter

     L. Pimpin et al. Is Butter Back? A Systematic Review and Meta-Analysis of Butter Consumption and Risk of Cardiovascular Disease, Diabetes, and Total Mortality. PLoS One, 11(6):e0158118, 2016. doi:10.1371/journal.pone.0158118 Evidence: Moderate

     Verified 2026-10-01 · PMID 27355649 · DOI 10.1371/journal.pone.0158118

     • Wiki: Butter
     • What Matters: Foods ranked for longevity

741. planaripoll2019danishnationwide

     O. Plana-Ripoll et al. A comprehensive analysis of mortality-related health metrics associated with mental disorders: a nationwide, register-based cohort study. Lancet, 394(10211):1827-1835, 2019. doi:10.1016/S0140-6736(19)32316-5 Evidence: Low

     Verified 2026-09-26 · PMID 31668728 · DOI 10.1016/S0140-6736(19)32316-5

     • Wiki: Mental health conditions and lifespan
     • Deep dive: The mental health conditions that cost the most years, ranked

742. plummer2015globalburden

     M. Plummer et al. Global burden of gastric cancer attributable to Helicobacter pylori. Int J Cancer, 136(2):487-90, 2015. doi:10.1002/ijc.28999 Evidence: Moderate

     Verified 2026-09-26 · PMID 24889903 · DOI 10.1002/ijc.28999

     • Wiki: Helicobacter pylori
     • Deep dive: H. pylori and stomach cancer: what the evidence shows
     • What Matters: What raises stomach cancer death risk

743. poggiogalle2018circadianregulation

     E. Poggiogalle, H. Jamshed, and C. M. Peterson. Circadian regulation of glucose, lipid, and energy metabolism in humans. Metabolism, 84:11-27, 2018. doi:10.1016/j.metabol.2017.11.017 Evidence: Very low

     Verified 2026-09-26 · PMID 29195759 · DOI 10.1016/j.metabol.2017.11.017

     • Wiki: Meal timing
     • Deep dive: Does an early last meal actually help you live longer?

744. polzer2012associationtooth

     I. Polzer et al. The association of tooth loss with all-cause and circulatory mortality. Is there a benefit of replaced teeth? A systematic review and meta-analysis. Clin Oral Investig, 16(2):333-51, 2012. doi:10.1007/s00784-011-0625-9 Evidence: Low

     Verified 2026-09-26 · PMID 22086361 · DOI 10.1007/s00784-011-0625-9

     • Wiki: Oral health
     • Deep dive: Does oral care actually affect how long you live?

745. pomirchy2025herpeszoster

     M. Pomirchy et al. Herpes Zoster Vaccination and Dementia Occurrence. JAMA, 333(23):2083-2092, 2025. doi:10.1001/jama.2025.5013 Evidence: Low

     Verified 2026-09-26 · PMID 40267506 · DOI 10.1001/jama.2025.5013

     • What Matters: What raises dementia risk most
     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • What Matters: Factors behind Alzheimer’s death risk
     • What Matters: The healthiest habits, ranked

746. poole2017umbrellacoffee

     R. Poole et al. Coffee consumption and health: umbrella review of meta-analyses of multiple health outcomes. BMJ, 359:j5024, 2017. doi:10.1136/bmj.j5024 Evidence: Moderate

     Verified 2026-09-27 · PMID 29167102 · DOI 10.1136/bmj.j5024

     • Wiki: Coffee, tea and energy drinks
     • Wiki: Coffee
     • What Matters: Foods ranked for longevity
     • Deep dive: The 7 things to know about coffee, tea, and energy drinks

747. poon2024hiitumbrella

     E. T. Poon et al. High-intensity interval training and cardiorespiratory fitness in adults: An umbrella review of systematic reviews and meta-analyses. Scand J Med Sci Sports, 34(5):e14652, 2024. doi:10.1111/sms.14652 Evidence: Moderate

     Verified 2026-09-26 · PMID 38760916 · DOI 10.1111/sms.14652

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: VO2 max
     • Wiki: Zone 2 training
     • Wiki: High-intensity interval training
     • Wiki: Cardio and aerobic fitness (section)
     • Deep dive: The 10 things that matter most for your heart

748. pope2002lungcancer

     C. A. Pope 3rd et al. Lung cancer, cardiopulmonary mortality, and long-term exposure to fine particulate air pollution. JAMA, 287(9):1132-41, 2002. doi:10.1001/jama.287.9.1132 Evidence: Low

     Verified 2026-09-26 · PMID 11879110 · DOI 10.1001/jama.287.9.1132

     • What Matters: Smoking and the rest: lung cancer death risk

749. pope2009airpollution

     C. A. Pope 3rd, M. Ezzati, and D. W. Dockery. Fine-particulate air pollution and life expectancy in the United States. N Engl J Med, 360(4):376-86, 2009. doi:10.1056/NEJMsa0805646 Evidence: Very low

     Verified 2026-09-26 · PMID 19164188 · DOI 10.1056/NEJMsa0805646

     • Quiz: Environment
     • What Matters: What Affects Lifespan the Most
     • What Matters: The healthiest habits, ranked

750. pourhadi2023menopausalhormone

     N. Pourhadi et al. Menopausal hormone therapy and dementia: nationwide, nested case-control study. BMJ, 381:e072770, 2023. doi:10.1136/bmj-2022-072770 Evidence: Low

     Verified 2026-09-27 · PMID 37380194 · DOI 10.1136/bmj-2022-072770

     • What Matters: What raises dementia risk most
     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • What Matters: Factors behind Alzheimer’s death risk

751. preston1994cancerincidence

     D. L. Preston et al. Cancer incidence in atomic bomb survivors. Part III. Leukemia, lymphoma and multiple myeloma, 1950-1987. Radiat Res, 137(2 Suppl):S68-97, 1994. Evidence: Low

     Verified 2026-09-26 · PMID 8127953

     • What Matters: What moves blood-cancer death risk

752. prospectivestudies2009bmi

     Prospective Studies Collaboration et al. Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies. Lancet, 373(9669):1083-96, 2009. doi:10.1016/S0140-6736(09)60318-4 Evidence: High

     Verified 2026-09-26 · PMID 19299006 · DOI 10.1016/S0140-6736(09)60318-4

     • Wiki: Body weight
     • Deep dive: The 8 things that matter most for your metabolism
     • Deep dive: How much is the extra weight actually costing you?
     • Quiz: Body weight
     • Quiz: Weight check
     • What Matters: Habits that swing heart-disease death risk
     • What Matters: What Affects Lifespan the Most
     • What Matters: The healthiest habits, ranked

753. qaseem2016acpguideline

     A. Qaseem et al. Management of Chronic Insomnia Disorder in Adults: A Clinical Practice Guideline From the American College of Physicians. Ann Intern Med, 165(2):125-33, 2016. doi:10.7326/M15-2175 Evidence: Not graded (guideline)

     Verified 2026-09-26 · PMID 27136449 · DOI 10.7326/M15-2175

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Insomnia
     • Wiki: Sleep quality
     • Wiki: Sleep (section)
     • Deep dive: The 8 things that matter most for your sleep
     • Deep dive: How sleep affects how long you live
     • Deep dive: What matters most for high-quality sleep
     • Deep dive: Bryan Johnson's Ten Sleep Power Laws: what each one asks and how strong the evidence is
     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

754. qi2021doseresponse

     X. Qi et al. Dose-Response Meta-Analysis on Tooth Loss With the Risk of Cognitive Impairment and Dementia. J Am Med Dir Assoc, 22(10):2039-2045, 2021. doi:10.1016/j.jamda.2021.05.009 Evidence: Moderate

     Verified 2026-09-26 · PMID 34579934 · DOI 10.1016/j.jamda.2021.05.009

     • Wiki: Oral health
     • What Matters: What raises dementia risk most
     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • Deep dive: Does oral care actually affect how long you live?
     • What Matters: Factors behind Alzheimer’s death risk

755. qi2025sleepduration

     J. Qi et al. The Association Between Sleep Duration and the Risk of Hypertension: A Systematic Review and Meta-analysis of Cohort Studies. J Gen Intern Med, 40(16):3848-3858, 2025. doi:10.1007/s11606-025-09398-6 Evidence: Moderate

     Verified 2026-09-26 · PMID 39904837 · DOI 10.1007/s11606-025-09398-6

     • What Matters: Levers on hypertensive disease deaths

756. qie2020obstructivesleep

     R. Qie et al. Obstructive sleep apnea and risk of type 2 diabetes mellitus: A systematic review and dose-response meta-analysis of cohort studies. J Diabetes, 12(6):455-464, 2020. doi:10.1111/1753-0407.13017 Evidence: High

     Verified 2026-09-26 · PMID 31872550 · DOI 10.1111/1753-0407.13017

     • What Matters: What moves diabetes death odds

757. qin2021fried

     P. Qin et al. Fried-food consumption and risk of cardiovascular disease and all-cause mortality: a meta-analysis of observational studies. Heart, 107(19):1567-1575, 2021. doi:10.1136/heartjnl-2020-317883 Evidence: Moderate

     Verified 2026-10-01 · PMID 33468573 · DOI 10.1136/heartjnl-2020-317883

     • Wiki: Fried foods
     • What Matters: Foods ranked for longevity

758. qiu2022metabolicsyndrome

     Y. Qiu et al. Systematic Review and Meta-analysis of the Association Between Metabolic Syndrome and Androgenetic Alopecia. Acta Derm Venereol, 102:adv00645, 2022. doi:10.2340/actadv.v101.1012 Evidence: Low

     Verified 2026-09-29 · PMID 34935992 · DOI 10.2340/actadv.v101.1012

     • Wiki: Hair loss

759. qureshi2009catownership

     A. I. Qureshi et al. Cat ownership and the Risk of Fatal Cardiovascular Diseases. Results from the Second National Health and Nutrition Examination Study Mortality Follow-up Study. J Vasc Interv Neurol, 2(1):132-5, 2009. Evidence: Low

     Verified 2026-09-26 · PMID 22518240

     • Wiki: Pet ownership
     • Deep dive: Does having a pet actually help you live longer?
     • What Matters: What Affects Lifespan the Most

760. ramne2019addedsugar

     S. Ramne et al. Association between added sugar intake and mortality is nonlinear and dependent on sugar source in 2 Swedish population-based prospective cohorts. Am J Clin Nutr, 109(2):411-423, 2019. doi:10.1093/ajcn/nqy268 Evidence: Low

     Verified 2026-10-01 · PMID 30590448 · DOI 10.1093/ajcn/nqy268

     • Wiki: Sweets and added sugar

761. rawshani2018riskfactors

     A. Rawshani et al. Risk Factors, Mortality, and Cardiovascular Outcomes in Patients with Type 2 Diabetes. N Engl J Med, 379(7):633-644, 2018. doi:10.1056/NEJMoa1800256 Evidence: Low

     Verified 2026-09-28 · PMID 30110583 · DOI 10.1056/NEJMoa1800256

     • Quiz: Metabolic health

762. reuben2016lestwe

     A. Reuben et al. Lest we forget: comparing retrospective and prospective assessments of adverse childhood experiences in the prediction of adult health. J Child Psychol Psychiatry, 57(10):1103-12, 2016. doi:10.1111/jcpp.12621 Evidence: Low

     Verified 2026-09-26 · PMID 27647050 · DOI 10.1111/jcpp.12621

     • Wiki: Adverse childhood experiences
     • Deep dive: Adverse childhood experiences: what an ACE score predicts, and what still helps now

763. reynolds2019fiber

     A. Reynolds et al. Carbohydrate quality and human health: a series of systematic reviews and meta-analyses. Lancet, 393(10170):434-445, 2019. doi:10.1016/S0140-6736(18)31809-9 Evidence: Moderate

     Verified 2026-09-26 · PMID 30638909 · DOI 10.1016/S0140-6736(18)31809-9

     • Wiki: Dietary patterns
     • Wiki: Dietary fiber
     • Wiki: Metabolic health and type 2 diabetes
     • Wiki: Colon health
     • Wiki: Diet and nutrition (section)
     • Wiki: Digestive and oral health (section)
     • Deep dive: The 8 things that matter most for your metabolism
     • Deep dive: The 8 things that matter most on your plate
     • Deep dive: The 9 things that matter most for your colon
     • Deep dive: Why doctors will not shut up about fiber
     • Deep dive: Vegan, vegetarian, omnivore, carnivore: what the labels actually buy you
     • Quiz: Gut & colon health
     • Quiz: Fiber
     • Quiz: Diet check
     • What Matters: Habits that swing heart-disease death risk
     • What Matters: What raises — or cuts — stroke death risk
     • What Matters: What Affects Lifespan the Most
     • What Matters: The healthiest habits, ranked

764. rice2012tuballigation

     M. S. Rice, M. A. Murphy, and S. S. Tworoger. Tubal ligation, hysterectomy and ovarian cancer: A meta-analysis. J Ovarian Res, 5(1):13, 2012. doi:10.1186/1757-2215-5-13 Evidence: High

     Verified 2026-09-26 · PMID 22587442 · DOI 10.1186/1757-2215-5-13

     • What Matters: What raises ovarian cancer death risk

765. richardson2012perceivedstress

     S. Richardson et al. Meta-analysis of perceived stress and its association with incident coronary heart disease. Am J Cardiol, 110(12):1711-6, 2012. doi:10.1016/j.amjcard.2012.08.004 Evidence: Moderate

     Verified 2026-09-26 · PMID 22975465 · DOI 10.1016/j.amjcard.2012.08.004

     • Wiki: Stress and anxiety
     • What Matters: Habits that swing heart-disease death risk

766. richier2026brainage

     C. Richier et al. Brain age prediction in generalized anxiety disorder using a convolutional neural network. Transl Psychiatry, 16(1):368, 2026. doi:10.1038/s41398-026-04078-3 Evidence: Very low

     Verified 2026-09-27 · PMID 42177199 · DOI 10.1038/s41398-026-04078-3

     • Deep dive: How to lower your cognitive age: every habit with a number in years

767. ricocampa2019ultraprocessed

     A. Rico-Campà et al. Association between consumption of ultra-processed foods and all cause mortality: SUN prospective cohort study. BMJ, 365:l1949, 2019. doi:10.1136/bmj.l1949 Evidence: Low

     Verified 2026-09-28 · PMID 31142450 · DOI 10.1136/bmj.l1949

     • Quiz: Diet check

768. ridker2016crpil6il1

     P. M. Ridker. From C-Reactive Protein to Interleukin-6 to Interleukin-1: Moving Upstream To Identify Novel Targets for Atheroprotection. Circ Res, 118(1):145-56, 2016. doi:10.1161/CIRCRESAHA.115.306656 Evidence: Very low

     Verified 2026-09-22 · PMID 26837745 · DOI 10.1161/CIRCRESAHA.115.306656

     PR #555 audit: the original PMID (26892964) resolved to an unrelated macrophage-phenotype paper (Tabas); corrected to 26837745.

     • Wiki: Inflammation and aging

769. ridker2017cantos

     P. M. Ridker et al. Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease. N Engl J Med, 377(12):1119-1131, 2017. doi:10.1056/NEJMoa1707914 Evidence: Moderate

     Verified 2026-09-22 · PMID 28845751 · DOI 10.1056/NEJMoa1707914

     • Wiki: Cardiovascular disease
     • Wiki: Inflammation and aging
     • Wiki: Longevity theories (section)
     • Deep dive: The 9 things that matter most for taming inflammation

770. ridker2019cirt

     P. M. Ridker et al. Low-Dose Methotrexate for the Prevention of Atherosclerotic Events. N Engl J Med, 380(8):752-762, 2019. doi:10.1056/NEJMoa1809798 Evidence: Moderate

     Verified 2026-09-28 · PMID 30415610 · DOI 10.1056/NEJMoa1809798

     • Wiki: Inflammation and aging

771. riemann2010hyperarousal

     D. Riemann et al. The hyperarousal model of insomnia: a review of the concept and its evidence. Sleep Med Rev, 14(1):19-31, 2010. doi:10.1016/j.smrv.2009.04.002 Evidence: Very low

     Verified 2026-09-22 · PMID 19481481 · DOI 10.1016/j.smrv.2009.04.002

     PR #555 audit: the original PMID (19910232) resolved to an unrelated brucellosis case series; corrected to 19481481.

     • Wiki: Insomnia
     • Deep dive: Bryan Johnson's Ten Sleep Power Laws: what each one asks and how strong the evidence is

772. riemann2022insomniadisorder

     D. Riemann et al. Insomnia disorder: State of the science and challenges for the future. J Sleep Res, 31(4):e13604, 2022. doi:10.1111/jsr.13604 Evidence: Not graded (review)

     Verified 2026-09-28 · PMID 35460140 · DOI 10.1111/jsr.13604

     • Wiki: Insomnia
     • Wiki: Sleep (section)
     • Deep dive: Bryan Johnson's Ten Sleep Power Laws: what each one asks and how strong the evidence is
     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

773. rod2020trajectorieschildhood

     N. H. Rod et al. Trajectories of childhood adversity and mortality in early adulthood: a population-based cohort study. Lancet, 396(10249):489-497, 2020. doi:10.1016/S0140-6736(20)30621-8 Evidence: Low

     Verified 2026-09-26 · PMID 32798491 · DOI 10.1016/S0140-6736(20)30621-8

     • Wiki: Adverse childhood experiences
     • Deep dive: Adverse childhood experiences: what an ACE score predicts, and what still helps now

774. roerecke2010irregularheavy

     M. Roerecke and J. Rehm. Irregular heavy drinking occasions and risk of ischemic heart disease: a systematic review and meta-analysis. Am J Epidemiol, 171(6):633-44, 2010. doi:10.1093/aje/kwp451 Evidence: Moderate

     Verified 2026-09-26 · PMID 20142394 · DOI 10.1093/aje/kwp451

     • Wiki: Alcohol
     • What Matters: Habits that swing heart-disease death risk

775. roerecke2017alcoholreduction

     M. Roerecke et al. The effect of a reduction in alcohol consumption on blood pressure: a systematic review and meta-analysis. Lancet Public Health, 2(2):e108-e120, 2017. doi:10.1016/S2468-2667(17)30003-8 Evidence: High

     Verified 2026-09-26 · PMID 29253389 · DOI 10.1016/S2468-2667(17)30003-8

     • Wiki: Alcohol
     • Wiki: Blood pressure
     • Deep dive: Is your blood pressure quietly aging you? The 9 things that matter most

776. roerecke2019alcoholconsumption

     M. Roerecke et al. Alcohol Consumption and Risk of Liver Cirrhosis: A Systematic Review and Meta-Analysis. Am J Gastroenterol, 114(10):1574-1586, 2019. doi:10.14309/ajg.0000000000000340 Evidence: Moderate

     Verified 2026-09-26 · PMID 31464740 · DOI 10.14309/ajg.0000000000000340

     • Wiki: Alcohol
     • What Matters: Factors that swing liver disease deaths

777. rogeberg2016cannabiscollision

     O. Rogeberg and R. Elvik. The effects of cannabis intoxication on motor vehicle collision revisited and revised. Addiction, 111(8):1348-59, 2016. doi:10.1111/add.13347 Evidence: Moderate

     Verified 2026-09-26 · PMID 26878835 · DOI 10.1111/add.13347

     • Wiki: Road safety
     • What Matters: Factors that swing accidental deaths

778. rogenmoser2018keepingbrains

     L. Rogenmoser et al. Keeping brains young with making music. Brain Struct Funct, 223(1):297-305, 2018. doi:10.1007/s00429-017-1491-2 Evidence: Very low

     Verified 2026-09-26 · PMID 28815301 · DOI 10.1007/s00429-017-1491-2

     • Wiki: Cognitive aging
     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

779. rojasrueda2019greenspaces

     D. Rojas-Rueda et al. Green spaces and mortality: a systematic review and meta-analysis of cohort studies. Lancet Planet Health, 3(11):e469-e477, 2019. doi:10.1016/S2542-5196(19)30215-3 Evidence: Moderate

     Verified 2026-09-26 · PMID 31777338 · DOI 10.1016/S2542-5196(19)30215-3

     • Wiki: Green space
     • Wiki: Environment and safety (section)
     • Deep dive: Does living somewhere green actually help you live longer?

780. ronan2016obesityassociated

     L. Ronan et al. Obesity associated with increased brain age from midlife. Neurobiol Aging, 47:63-70, 2016. doi:10.1016/j.neurobiolaging.2016.07.010 Evidence: Very low

     Verified 2026-09-26 · PMID 27562529 · DOI 10.1016/j.neurobiolaging.2016.07.010

     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years

781. roosli2019noisefield

     M. Röösli et al. Associations of Various Nighttime Noise Exposure Indicators with Objective Sleep Efficiency and Self-Reported Sleep Quality: A Field Study. Int J Environ Res Public Health, 16(20), 2019. doi:10.3390/ijerph16203790 Evidence: Very low

     Verified 2026-09-26 · PMID 31600891 · DOI 10.3390/ijerph16203790

     • What Matters: What actually moves sleep quality
     • Deep dive: What matters most for high-quality sleep
     • Deep dive: Top 10 insomnia remedies, ranked by the evidence
     • What Matters: The healthiest habits, ranked

782. rostekova2025longitudinalrelationships

     A. Rostekova et al. Longitudinal relationships between pet ownership and cognitive functioning in later adulthood across pet types and individuals' ages. Sci Rep, 15(1):19066, 2025. doi:10.1038/s41598-025-03727-9 Evidence: Low

     Verified 2026-09-26 · PMID 40447721 · DOI 10.1038/s41598-025-03727-9

     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

783. rota2014alcoholdrinking

     M. Rota et al. Alcohol drinking and cutaneous melanoma risk: a systematic review and dose-risk meta-analysis. Br J Dermatol, 170(5):1021-8, 2014. doi:10.1111/bjd.12856 Evidence: Low

     Verified 2026-09-26 · PMID 24495200 · DOI 10.1111/bjd.12856

     • What Matters: Sun and the rest: melanoma death risk

784. rota2024doseresponse

     M. Rota et al. Dose-response association between cigarette smoking and gastric cancer risk: a systematic review and meta-analysis. Gastric Cancer, 27(2):197-209, 2024. doi:10.1007/s10120-023-01459-1 Evidence: High

     Verified 2026-09-26 · PMID 38231449 · DOI 10.1007/s10120-023-01459-1

     • Wiki: Helicobacter pylori
     • Deep dive: H. pylori and stomach cancer: what the evidence shows
     • What Matters: What raises stomach cancer death risk

785. roth2020gbdcvd

     G. A. Roth et al. Global Burden of Cardiovascular Diseases and Risk Factors, 1990-2019: Update From the GBD 2019 Study. J Am Coll Cardiol, 76(25):2982-3021, 2020. doi:10.1016/j.jacc.2020.11.010 Evidence: Moderate

     Verified 2026-09-29 · PMID 33309175 · DOI 10.1016/j.jacc.2020.11.010

     • Wiki: Cardiovascular disease
     • Wiki: Heart and metabolic health (section)

786. rothwell2010longterm

     P. M. Rothwell et al. Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials. Lancet, 376(9754):1741-50, 2010. doi:10.1016/S0140-6736(10)61543-7 Evidence: Moderate

     Verified 2026-09-26 · PMID 20970847 · DOI 10.1016/S0140-6736(10)61543-7

     • What Matters: What changes bowel cancer death risk

787. rothwell2011effectdaily

     P. M. Rothwell et al. Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials. Lancet, 377(9759):31-41, 2011. doi:10.1016/S0140-6736(10)62110-1 Evidence: High

     Verified 2026-09-26 · PMID 21144578 · DOI 10.1016/S0140-6736(10)62110-1

     • What Matters: Habits that change cancer death risk

788. ruan2018dietaryfat

     Y. Ruan et al. Dietary Fat Intake and Risk of Alzheimer's Disease and Dementia: A Meta-Analysis of Cohort Studies. Curr Alzheimer Res, 15(9):869-876, 2018. doi:10.2174/1567205015666180427142350 Evidence: Low

     Verified 2026-09-26 · PMID 29701155 · DOI 10.2174/1567205015666180427142350

     • Deep dive: Plants and your brain: what the vegetarian, Mediterranean and MIND studies really show about dementia

789. ruby2018heritabilitylongevity

     J. G. Ruby et al. Estimates of the Heritability of Human Longevity Are Substantially Inflated due to Assortative Mating. Genetics, 210(3):1109-1124, 2018. doi:10.1534/genetics.118.301613 Evidence: Low

     Verified 2026-09-26 · PMID 30401766 · DOI 10.1534/genetics.118.301613

     • Wiki: Family history and genetics
     • Wiki: Longevity theories (section)
     • Deep dive: What you inherit from your family, and what you don’t

790. rumgay2021globalcancer

     H. Rumgay et al. Global burden of cancer in 2020 attributable to alcohol consumption: a population-based study. Lancet Oncol, 22(8):1071-1080, 2021. doi:10.1016/S1470-2045(21)00279-5 Evidence: Moderate

     Verified 2026-09-26 · PMID 34270924 · DOI 10.1016/S1470-2045(21)00279-5

     • Wiki: Alcohol
     • Wiki: Alcohol and tobacco (section)
     • Deep dive: The 7 things to know about alcohol
     • What Matters: Habits that change cancer death risk

791. rumgay2026globalburden

     H. Rumgay et al. Global burden of cancer attributable to infections in 2024: a worldwide incidence analysis. Lancet Oncol, 27(10):1237-1248, 2026. doi:10.1016/S1470-2045(26)00307-4 Evidence: Moderate

     Verified 2026-10-04 · PMID 42805198 · DOI 10.1016/S1470-2045(26)00307-4

     • Wiki: Helicobacter pylori
     • Wiki: Digestive and oral health (section)
     • Deep dive: H. pylori and stomach cancer: what the evidence shows

792. runyan1992residentialfires

     C. W. Runyan et al. Risk factors for fatal residential fires. N Engl J Med, 327(12):859-63, 1992. doi:10.1056/NEJM199209173271207 Evidence: Low

     Verified 2026-09-26 · PMID 1508246 · DOI 10.1056/NEJM199209173271207

     • What Matters: Factors that swing accidental deaths

793. rusch2019mindfulnesssleep

     H. L. Rusch et al. The effect of mindfulness meditation on sleep quality: a systematic review and meta-analysis of randomized controlled trials. Ann N Y Acad Sci, 1445(1):5-16, 2019. doi:10.1111/nyas.13996 Evidence: Moderate

     Verified 2026-10-08 · PMID 30575050 · DOI 10.1111/nyas.13996

     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

794. russ2012psychologicaldistress

     T. C. Russ et al. Association between psychological distress and mortality: individual participant pooled analysis of 10 prospective cohort studies. BMJ, 345:e4933, 2012. doi:10.1136/bmj.e4933 Evidence: High

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     • Wiki: Stress and anxiety
     • Wiki: Mental health and relationships (section)
     • Deep dive: The 8 things that matter most for staying calm
     • Quiz: Calm check

795. sabag2024exercisetiming

     A. Sabag et al. Timing of Moderate to Vigorous Physical Activity, Mortality, Cardiovascular Disease, and Microvascular Disease in Adults With Obesity. Diabetes Care, 47(5):890-897, 2024. doi:10.2337/dc23-2448 Evidence: Low

     Verified 2026-09-26 · PMID 38592034 · DOI 10.2337/dc23-2448

     • What Matters: What sleep does to how long you live
     • Deep dive: How sleep affects how long you live
     • What Matters: The healthiest habits, ranked

796. sabatine2017fourierevolocumab

     M. S. Sabatine et al. Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease. N Engl J Med, 376(18):1713-1722, 2017. doi:10.1056/NEJMoa1615664 Evidence: Moderate

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Cholesterol
     • Deep dive: The 9 things that matter most for your cholesterol

797. sabia2012impactsmoking

     S. Sabia et al. Impact of smoking on cognitive decline in early old age: the Whitehall II cohort study. Arch Gen Psychiatry, 69(6):627-35, 2012. doi:10.1001/archgenpsychiatry.2011.2016 Evidence: Low

     Verified 2026-09-26 · PMID 22309970 · DOI 10.1001/archgenpsychiatry.2011.2016

     • Wiki: Cognitive aging
     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years

798. sabia2021sleepduration

     S. Sabia et al. Association of sleep duration in middle and old age with incidence of dementia. Nat Commun, 12(1):2289, 2021. doi:10.1038/s41467-021-22354-2 Evidence: Low

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     • Wiki: Sleep physiology
     • Wiki: Sleep duration and mortality
     • Wiki: Dementia risk factors
     • Wiki: Sleep (section)
     • What Matters: What raises dementia risk most
     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • Deep dive: The 8 things to know about Alzheimer’s risk
     • Deep dive: How sleep affects how long you live
     • What Matters: Factors behind Alzheimer’s death risk
     • What Matters: The healthiest habits, ranked

799. sacks2001dashsodium

     F. M. Sacks et al. Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. DASH-Sodium Collaborative Research Group. N Engl J Med, 344(1):3-10, 2001. doi:10.1056/NEJM200101043440101 Evidence: Low

     Verified 2026-09-26 · PMID 11136953 · DOI 10.1056/NEJM200101043440101

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Blood pressure
     • Deep dive: Is your blood pressure quietly aging you? The 9 things that matter most

800. saintjacques2014arsenicdrinking

     N. Saint-Jacques et al. Arsenic in drinking water and urinary tract cancers: a systematic review of 30 years of epidemiological evidence. Environ Health, 13:44, 2014. doi:10.1186/1476-069X-13-44 Evidence: Moderate

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     • What Matters: What changes bladder cancer death risk

801. saintmaurice2019leisureactivity

     P. F. Saint-Maurice et al. Association of Leisure-Time Physical Activity Across the Adult Life Course With All-Cause and Cause-Specific Mortality. JAMA Netw Open, 2(3):e190355, 2019. doi:10.1001/jamanetworkopen.2019.0355 Evidence: Low

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Exercise and longevity
     • Wiki: Sports and active hobbies
     • What Matters: Movement: What Matters?

802. sanchezlastra2021stairclimbing

     M. A. Sanchez‐Lastra et al. Stair climbing and mortality: a prospective cohort study from the UK Biobank. J Cachexia Sarcopenia Muscle, 12(2):298-307, 2021. doi:10.1002/jcsm.12679 Evidence: Low

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Walking and daily steps
     • What Matters: Movement: What Matters?

803. sandstrom2014weakties

     G. M. Sandstrom and E. W. Dunn. Social Interactions and Well-Being. Pers Soc Psychol Bull, 40(7):910-922, 2014. doi:10.1177/0146167214529799 Evidence: Very low

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Social connection
     • Deep dive: The 8 things that matter most for connection and purpose

804. saneei2017rice

     P. Saneei, B. Larijani, and A. Esmaillzadeh. Rice consumption, incidence of chronic diseases and risk of mortality: meta-analysis of cohort studies. Public Health Nutr, 20(2):233-244, 2017. doi:10.1017/S1368980016002172 Evidence: Moderate

     Verified 2026-10-01 · PMID 27577106 · DOI 10.1017/S1368980016002172

     • Wiki: White rice
     • What Matters: Foods ranked for longevity

805. sanmillan2018metabolicflexibility

     I. San-Millán and G. A. Brooks. Assessment of Metabolic Flexibility by Means of Measuring Blood Lactate, Fat, and Carbohydrate Oxidation Responses to Exercise in Professional Endurance Athletes and Less-Fit Individuals. Sports Med, 48(2):467-479, 2018. doi:10.1007/s40279-017-0751-x Evidence: Very low

     Verified 2026-09-28 · PMID 28623613 · DOI 10.1007/s40279-017-0751-x

     • Wiki: Zone 2 training

806. sanz2020periodontitiscardiovascular

     M. Sanz et al. Periodontitis and cardiovascular diseases: Consensus report. J Clinic Periodontology, 47(3):268-288, 2020. doi:10.1111/jcpe.13189 Evidence: Not graded (guideline)

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Oral health
     • Wiki: Digestive and oral health (section)
     • Deep dive: The 9 things that matter most for taming inflammation
     • Deep dive: Does oral care actually affect how long you live?
     • Quiz: Preventive care

807. saper2005hypothalamic

     C. B. Saper, T. E. Scammell, and J. Lu. Hypothalamic regulation of sleep and circadian rhythms. Nature, 437(7063):1257-63, 2005. doi:10.1038/nature04284 Evidence: Very low

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     • Wiki: Sleep physiology
     • Wiki: Sleep (section)

808. sarwarnaerfclancet

     Emerging Risk Factors Collaboration et al. Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies. Lancet, 375(9733):2215-22, 2010. doi:10.1016/S0140-6736(10)60484-9 Evidence: High

     Verified 2026-09-26 · PMID 20609967 · DOI 10.1016/S0140-6736(10)60484-9

     • What Matters: Habits that swing heart-disease death risk
     • What Matters: What raises — or cuts — stroke death risk

809. sasaki2020riskhypertension

     N. Sasaki et al. Risk of hypertension in middle-aged and elderly participants with newly diagnosed type 2 diabetes and prediabetes. BMJ Open Diabetes Res Care, 8(1):e001500, 2020. doi:10.1136/bmjdrc-2020-001500 Evidence: Low

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     • What Matters: Levers on hypertensive disease deaths

810. sateia2017aasminsomniadrugs

     M. J. Sateia et al. Clinical Practice Guideline for the Pharmacologic Treatment of Chronic Insomnia in Adults: An American Academy of Sleep Medicine Clinical Practice Guideline. J Clin Sleep Med, 13(2):307-349, 2017. doi:10.5664/jcsm.6470 Evidence: Not graded (guideline)

     Verified 2026-09-28 · PMID 27998379 · DOI 10.5664/jcsm.6470

     Clinical practice guideline: left untiered per the §3 rubric (a guideline stays untiered).

     • Wiki: Supplements (section)
     • Wiki: Melatonin (supplement)
     • Wiki: Valerian (supplement)
     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

811. satija2017healthfulunhealthful

     A. Satija et al. Healthful and Unhealthful Plant-Based Diets and the Risk of Coronary Heart Disease in U.S. Adults. J Am Coll Cardiol, 70(4):411-422, 2017. doi:10.1016/j.jacc.2017.05.047 Evidence: Moderate

     Verified 2026-09-26 · PMID 28728684 · DOI 10.1016/j.jacc.2017.05.047

     • Wiki: Dietary patterns
     • Wiki: Diet and nutrition (section)
     • Deep dive: Vegan, vegetarian, omnivore, carnivore: what the labels actually buy you

812. scheer2012melatoninbetablockers

     F. A. Scheer et al. Repeated melatonin supplementation improves sleep in hypertensive patients treated with beta-blockers: a randomized controlled trial. Sleep, 35(10):1395-402, 2012. doi:10.5665/sleep.2122 Evidence: Low

     Verified 2026-09-22 · PMID 23024438 · DOI 10.5665/sleep.2122

     PR #555 audit: the original PMID (22654195) resolved to an unrelated portable-sleep-study-vs-PSG paper; corrected to 23024438.

     • Wiki: Melatonin (supplement)
     • What Matters: What actually moves sleep quality
     • Deep dive: What matters most for high-quality sleep

813. schmid2014televisionviewing

     D. Schmid and M. F. Leitzmann. Television viewing and time spent sedentary in relation to cancer risk: a meta-analysis. J Natl Cancer Inst, 106(7):dju098, 2014. doi:10.1093/jnci/dju098 Evidence: High

     Verified 2026-09-27 · PMID 24935969 · DOI 10.1093/jnci/dju098

     • Wiki: Sedentary time
     • What Matters: Habits that change uterine cancer death risk
     • What Matters: Habits that change uterine cancer death risk

814. schneider2005transcendentalmeditation

     R. H. Schneider et al. Long-term effects of stress reduction on mortality in persons ≥55 years of age with systemic hypertension. Am J Cardiol, 95(9):1060-4, 2005. doi:10.1016/j.amjcard.2004.12.058 Evidence: Low

     Verified 2026-09-26 · PMID 15842971 · DOI 10.1016/j.amjcard.2004.12.058

     • What Matters: What sleep does to how long you live
     • Deep dive: How sleep affects how long you live
     • What Matters: The healthiest habits, ranked

815. schnohr2018copenhagencity

     P. Schnohr et al. Various Leisure-Time Physical Activities Associated With Widely Divergent Life Expectancies: The Copenhagen City Heart Study. Mayo Clin Proc, 93(12):1775-1785, 2018. doi:10.1016/j.mayocp.2018.06.025 Evidence: Low

     Verified 2026-09-26 · DOI 10.1016/j.mayocp.2018.06.025

     • Wiki: Sports and active hobbies
     • Wiki: Everyday movement (section)
     • What Matters: Movement: What Matters?
     • Deep dive: The sports that add the most years, ranked
     • Quiz: Exercise

816. schoenfeld2017loadhypertrophy

     B. J. Schoenfeld et al. Strength and Hypertrophy Adaptations Between Low- vs. High-Load Resistance Training: A Systematic Review and Meta-analysis. J Strength Cond Res, 31(12):3508-3523, 2017. doi:10.1519/JSC.0000000000002200 Evidence: Moderate

     Verified 2026-09-28 · PMID 28834797 · DOI 10.1519/JSC.0000000000002200

     • Wiki: Resistance training
     • Wiki: Muscle mass

817. schoenfeld2017trainingvolume

     B. J. Schoenfeld, D. Ogborn, and J. W. Krieger. Dose-response relationship between weekly resistance training volume and increases in muscle mass: A systematic review and meta-analysis. J Sports Sci, 35(11):1073-1082, 2017. doi:10.1080/02640414.2016.1210197 Evidence: Low

     Verified 2026-09-28 · PMID 27433992 · DOI 10.1080/02640414.2016.1210197

     • Wiki: Resistance training
     • Wiki: Muscle mass

818. schulte1986riskfactors

     P. A. Schulte et al. Risk factors for bladder cancer in a cohort exposed to aromatic amines. Cancer, 58(9):2156-62, 1986. doi:10.1002/1097-0142(19861101)58:9<2156::aid-cncr2820580933>3.0.co;2-y Evidence: Low

     Verified 2026-09-26 · PMID 3756832 · DOI 10.1002/1097-0142(19861101)58:9<2156::aid-cncr2820580933>3.0.co;2-y

     • What Matters: What changes bladder cancer death risk

819. schwarzinger2018alcoholearly

     M. Schwarzinger et al. Contribution of alcohol use disorders to the burden of dementia in France 2008-13: a nationwide retrospective cohort study. Lancet Public Health, 3(3):e124-e132, 2018. doi:10.1016/S2468-2667(18)30022-7 Evidence: Low

     Verified 2026-09-26 · PMID 29475810 · DOI 10.1016/S2468-2667(18)30022-7

     • Wiki: Alcohol
     • Wiki: Dementia risk factors
     • Deep dive: How to escape dementia: all 14 risk factors, ranked

820. schwingshackl2017foodgroups

     L. Schwingshackl et al. Food groups and risk of all-cause mortality: a systematic review and meta-analysis of prospective studies. Am J Clin Nutr, 105(6):1462-1473, 2017. doi:10.3945/ajcn.117.153148 Evidence: High

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     • Wiki: Nuts
     • Wiki: Fruit
     • Wiki: Whole grains
     • Wiki: Vegetables
     • Wiki: Red meat
     • Wiki: Processed meat
     • Wiki: Foods (section)
     • What Matters: Foods ranked for longevity

821. schwingshackl2019potatoes

     L. Schwingshackl et al. Potatoes and risk of chronic disease: a systematic review and dose-response meta-analysis. Eur J Nutr, 58(6):2243-2251, 2019. doi:10.1007/s00394-018-1774-2 Evidence: Moderate

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     • Wiki: Potatoes
     • What Matters: Foods ranked for longevity

822. scullin2018todolist

     M. K. Scullin et al. The effects of bedtime writing on difficulty falling asleep: A polysomnographic study comparing to-do lists and completed activity lists. J Exp Psychol Gen, 147(1):139-146, 2018. doi:10.1037/xge0000374 Evidence: Low

     Verified 2026-10-08 · PMID 29058942 · DOI 10.1037/xge0000374

     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

823. see1995vigilancedecrement

     J. E. See et al. Meta-analysis of the sensitivity decrement in vigilance. Psychol Bull, 117(2):230-249, 1995. doi:10.1037/0033-2909.117.2.230 Evidence: Not graded (design not checkable)

     Verified 2026-09-26 · DOI 10.1037/0033-2909.117.2.230

     • What Matters: What stretches, or shreds, attention

824. seer2026commoncancersites

     National Cancer Institute SEER Program. Common Cancer Sites: Cancer Stat Facts. National Cancer Institute. Evidence: Not graded (statistics)

     Verified 2026-09-28

     Page title read from the live page on 2026-09-28. Backs the share of cancer deaths by site (SEER/NCHS) on the cancer page and hub.

     • What Matters: Causes of death (population baselines)

825. seidelmann2018dietarycarbohydrate

     S. B. Seidelmann et al. Dietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis. Lancet Public Health, 3(9):e419-e428, 2018. doi:10.1016/S2468-2667(18)30135-X Evidence: High

     Verified 2026-09-26 · PMID 30122560 · DOI 10.1016/S2468-2667(18)30135-X

     • Wiki: Dietary patterns
     • Deep dive: Vegan, vegetarian, omnivore, carnivore: what the labels actually buy you
     • Quiz: Diet

826. seidu2023physicalactivity

     S. Seidu et al. Physical activity and risk of chronic kidney disease: systematic review and meta-analysis of 12 cohort studies involving 1,281,727 participants. Eur J Epidemiol, 38(3):267-280, 2023. doi:10.1007/s10654-022-00961-7 Evidence: Low

     Verified 2026-09-26 · PMID 36626101 · DOI 10.1007/s10654-022-00961-7

     Authors graded the evidence quality low (GRADE).

     • What Matters: Factors that swing kidney disease deaths

827. selvin2007weightloss

     E. Selvin. The Effect of Weight Loss on C-Reactive Protein. Arch Intern Med, 167(1):31, 2007. doi:10.1001/archinte.167.1.31 Evidence: Moderate

     Verified 2026-09-26 · DOI 10.1001/archinte.167.1.31

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Inflammation and aging
     • Deep dive: The 9 things that matter most for taming inflammation

828. seppanen2006temperatureoffice

     O. Seppänen, W. J. Fisk, and Q. H. Lei. Effect of temperature on task performance in office environment. Lawrence Berkeley National Laboratory (report LBNL-60946), 2006. Evidence: Low

     Verified 2026-09-27

     • What Matters: What stretches, or shreds, attention

829. sergentanis2013obesityrisk

     T. N. Sergentanis et al. Obesity and risk of malignant melanoma: a meta-analysis of cohort and case-control studies. Eur J Cancer, 49(3):642-57, 2013. doi:10.1016/j.ejca.2012.08.028 Evidence: Moderate

     Verified 2026-09-26 · PMID 23200191 · DOI 10.1016/j.ejca.2012.08.028

     • What Matters: Sun and the rest: melanoma death risk

830. seshadri2010parentaloccurrence

     S. Seshadri et al. Parental occurrence of stroke and risk of stroke in their children: the Framingham study. Circulation, 121(11):1304-12, 2010. doi:10.1161/CIRCULATIONAHA.109.854240 Evidence: Low

     Verified 2026-09-26 · PMID 20212282 · DOI 10.1161/CIRCULATIONAHA.109.854240

     • Wiki: Family history and genetics
     • Deep dive: What you inherit from your family, and what you don’t
     • What Matters: What raises — or cuts — stroke death risk
     • What Matters: What Affects Lifespan the Most

831. shah2019energydrinks

     S. A. Shah et al. Impact of High Volume Energy Drink Consumption on Electrocardiographic and Blood Pressure Parameters: A Randomized Trial. J Am Heart Assoc, 8(11), 2019. doi:10.1161/JAHA.118.011318 Evidence: Low

     Verified 2026-09-26 · DOI 10.1161/JAHA.118.011318

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Coffee, tea and energy drinks
     • Deep dive: The 7 things to know about coffee, tea, and energy drinks
     • Quiz: Caffeine check

832. shan2015sleepduration

     Z. Shan et al. Sleep duration and risk of type 2 diabetes: a meta-analysis of prospective studies. Diabetes Care, 38(3):529-37, 2015. doi:10.2337/dc14-2073 Evidence: High

     Verified 2026-09-26 · PMID 25715415 · DOI 10.2337/dc14-2073

     • Wiki: Metabolic health and type 2 diabetes
     • Deep dive: The 9 factors that decide your type 2 diabetes risk

833. shannon2023mediterraneandiet

     O. M. Shannon et al. Mediterranean diet adherence is associated with lower dementia risk, independent of genetic predisposition: findings from the UK Biobank prospective cohort study. BMC Med, 21(1):81, 2023. doi:10.1186/s12916-023-02772-3 Evidence: Low

     Verified 2026-09-26 · PMID 36915130 · DOI 10.1186/s12916-023-02772-3

     • Wiki: Dementia risk factors
     • What Matters: What raises dementia risk most
     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • Deep dive: Plants and your brain: what the vegetarian, Mediterranean and MIND studies really show about dementia
     • What Matters: Factors behind Alzheimer’s death risk
     • What Matters: The healthiest habits, ranked

834. shaw2021lonelinesssuicide

     R. J. Shaw et al. Living alone, loneliness and lack of emotional support as predictors of suicide and self-harm: A nine-year follow up of the UK Biobank cohort. J Affect Disord, 279:316-323, 2021. doi:10.1016/j.jad.2020.10.026 Evidence: Low

     Verified 2026-09-26 · PMID 33096330 · DOI 10.1016/j.jad.2020.10.026

     Metadata confirmed against the Europe PMC MEDLINE record for this PMID (NCBI E-utilities unavailable 2026-09-26). No issue number in the record.

     • What Matters: Factors linked to suicide deaths

835. shay2019telomerescancer

     J. W. Shay and W. E. Wright. Telomeres and telomerase: three decades of progress. Nat Rev Genet, 20(5):299-309, 2019. doi:10.1038/s41576-019-0099-1 Evidence: Very low

     Verified 2026-09-22 · PMID 30760854 · DOI 10.1038/s41576-019-0099-1

     PR #555 audit: the original PMID (30978969) resolved to an unrelated job-insecurity study; corrected to 30760854. Journal is Nature Reviews Genetics, not Nature Reviews Cancer as one wiki page's prose said.

     • Wiki: Telomeres

836. sherrington2017exercisefalls

     C. Sherrington et al. Exercise to prevent falls in older adults: an updated systematic review and meta-analysis. Br J Sports Med, 51(24):1750-1758, 2017. doi:10.1136/bjsports-2016-096547 Evidence: High

     Verified 2026-09-28 · PMID 27707740 · DOI 10.1136/bjsports-2016-096547

     • Wiki: Balance training
     • Wiki: Fall prevention

837. sherrington2019falls

     C. Sherrington et al. Exercise for preventing falls in older people living in the community. Cochrane Database Syst Rev, 1(1):CD012424, 2019. doi:10.1002/14651858.CD012424.pub2 Evidence: High

     Verified 2026-09-28 · PMID 30703272 · DOI 10.1002/14651858.CD012424.pub2

     • Wiki: Exercise and longevity
     • Wiki: Balance training
     • Wiki: Flexibility and mobility
     • Wiki: Functional fitness
     • Wiki: Fall prevention
     • Wiki: Yoga and tai chi
     • Wiki: Exercise (section)
     • Wiki: Balance, mobility and function (section)
     • Wiki: Everyday movement (section)

838. shi2018sleepdisturbances

     L. Shi et al. Sleep disturbances increase the risk of dementia: A systematic review and meta-analysis. Sleep Med Rev, 40:4-16, 2018. doi:10.1016/j.smrv.2017.06.010 Evidence: Moderate

     Verified 2026-09-26 · PMID 28890168 · DOI 10.1016/j.smrv.2017.06.010

     • What Matters: What raises dementia risk most
     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • What Matters: Factors behind Alzheimer’s death risk
     • What Matters: The healthiest habits, ranked

839. shields2016acutestress

     G. S. Shields, M. A. Sazma, and A. P. Yonelinas. The effects of acute stress on core executive functions: A meta-analysis and comparison with cortisol. Neurosci Biobehav Rev, 68:651-668, 2016. doi:10.1016/j.neubiorev.2016.06.038 Evidence: Moderate

     Verified 2026-09-27 · PMID 27371161 · DOI 10.1016/j.neubiorev.2016.06.038

     • What Matters: What stretches, or shreds, attention

840. shokrikojori2018onenight

     E. Shokri-Kojori et al. β-Amyloid accumulation in the human brain after one night of sleep deprivation. Proc Natl Acad Sci U S A, 115(17):4483-4488, 2018. doi:10.1073/pnas.1721694115 Evidence: Very low

     Verified 2026-09-26 · DOI 10.1073/pnas.1721694115

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Sleep physiology
     • Wiki: Dementia risk factors
     • Deep dive: The 8 things to know about Alzheimer’s risk

841. shumaker2003whimsestrogen

     S. A. Shumaker et al. Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial. JAMA, 289(20):2651-62, 2003. doi:10.1001/jama.289.20.2651 Evidence: Moderate

     Verified 2026-09-27 · PMID 12771112 · DOI 10.1001/jama.289.20.2651

     Previously pointed at the companion WHIMS cognitive-function paper (Rapp 2003, PMID 12771113); corrected 2026-09-27 to the dementia-incidence paper the cited HR comes from.

     • What Matters: What raises dementia risk most
     • What Matters: Factors behind Alzheimer’s death risk

842. shumaker2004whimsconjugated

     S. A. Shumaker et al. Conjugated equine estrogens and incidence of probable dementia and mild cognitive impairment in postmenopausal women: Women's Health Initiative Memory Study. JAMA, 291(24):2947-58, 2004. doi:10.1001/jama.291.24.2947 Evidence: Moderate

     Verified 2026-09-26 · PMID 15213206 · DOI 10.1001/jama.291.24.2947

     • What Matters: What raises dementia risk most
     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • What Matters: Factors behind Alzheimer’s death risk

843. siegel2023colorectalcancer

     R. L. Siegel et al. Colorectal cancer statistics, 2023. CA A Cancer J Clinicians, 73(3):233-254, 2023. doi:10.3322/caac.21772 Evidence: Not graded (statistics)

     Verified 2026-09-26 · DOI 10.3322/caac.21772

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Colon health
     • Wiki: Digestive and oral health (section)
     • Deep dive: The 9 things that matter most for your colon
     • Quiz: Gut & colon health

844. simon2020physicalactivity

     T. G. Simon et al. Physical activity compared to adiposity and risk of liver-related mortality: Results from two prospective, nationwide cohorts. J Hepatol, 72(6):1062-1069, 2020. doi:10.1016/j.jhep.2019.12.022 Evidence: Moderate

     Verified 2026-09-26 · PMID 31954204 · DOI 10.1016/j.jhep.2019.12.022

     • What Matters: Factors that swing liver disease deaths

845. simou2018alcoholpneumonia

     E. Simou, J. Britton, and J. Leonardi-Bee. Alcohol and the risk of pneumonia: a systematic review and meta-analysis. BMJ Open, 8(8):e022344, 2018. doi:10.1136/bmjopen-2018-022344 Evidence: Moderate

     Verified 2026-09-26 · PMID 30135186 · DOI 10.1136/bmjopen-2018-022344

     • What Matters: Factors that swing flu and pneumonia deaths

846. sims2023donanemab

     J. R. Sims et al. Donanemab in Early Symptomatic Alzheimer Disease: The TRAILBLAZER-ALZ 2 Randomized Clinical Trial. JAMA, 330(6):512-527, 2023. doi:10.1001/jama.2023.13239 Evidence: Moderate

     Verified 2026-09-28 · PMID 37459141 · DOI 10.1001/jama.2023.13239

     • Wiki: Dementia risk factors
     • Deep dive: The 8 things to know about Alzheimer’s risk

847. singh2014mediterraneandiet

     B. Singh et al. Association of mediterranean diet with mild cognitive impairment and Alzheimer's disease: a systematic review and meta-analysis. J Alzheimers Dis, 39(2):271-82, 2014. doi:10.3233/JAD-130830 Evidence: Moderate

     Verified 2026-09-26 · PMID 24164735 · DOI 10.3233/JAD-130830

     • Wiki: Dementia risk factors
     • Deep dive: Plants and your brain: what the vegetarian, Mediterranean and MIND studies really show about dementia

848. singhmanoux2012cognitivedecline

     A. Singh-Manoux et al. Timing of onset of cognitive decline: results from Whitehall II prospective cohort study. BMJ, 344:d7622, 2012. doi:10.1136/bmj.d7622 Evidence: Low

     Verified 2026-09-29 · PMID 22223828 · DOI 10.1136/bmj.d7622

     • Wiki: Cognitive aging
     • Wiki: Brain health (section)

849. skinnaskincancer

     Skin Cancer Foundation. Skin Cancer Prevention. Skin Cancer Foundation. Evidence: Not graded (reference page)

     Verified 2026-09-27

     Continuously-updated patient resource page, no single publication year stated.

     • Deep dive: The 9 things balding is actually telling you about your health

850. smith2010aerobicexercise

     P. J. Smith et al. Aerobic exercise and neurocognitive performance: a meta-analytic review of randomized controlled trials. Psychosom Med, 72(3):239-52, 2010. doi:10.1097/psy.0b013e3181d14633 Evidence: Moderate

     Verified 2026-09-27 · PMID 20223924 · DOI 10.1097/psy.0b013e3181d14633

     • What Matters: What stretches, or shreds, attention

851. smith2010homocysteinelowering

     A. D. Smith et al. Homocysteine-Lowering by B Vitamins Slows the Rate of Accelerated Brain Atrophy in Mild Cognitive Impairment: A Randomized Controlled Trial. PLoS One, 5(9):e12244, 2010. doi:10.1371/journal.pone.0012244 Evidence: Low

     Verified 2026-09-26 · DOI 10.1371/journal.pone.0012244

     • Deep dive: How to lower your cognitive age: every habit with a number in years

852. smitten2008incidencemalignancy

     A. L. Smitten et al. A meta-analysis of the incidence of malignancy in adult patients with rheumatoid arthritis. Arthritis Res Ther, 10(2):R45, 2008. doi:10.1186/ar2404 Evidence: High

     Verified 2026-09-26 · PMID 18433475 · DOI 10.1186/ar2404

     • What Matters: What moves blood-cancer death risk

853. sniderman2019apolipoproteinb

     A. D. Sniderman et al. Apolipoprotein B Particles and Cardiovascular Disease: A Narrative Review. JAMA Cardiol, 4(12):1287-1295, 2019. doi:10.1001/jamacardio.2019.3780 Evidence: Very low

     Verified 2026-09-28 · PMID 31642874 · DOI 10.1001/jamacardio.2019.3780

     • Wiki: Cardiovascular disease
     • Wiki: Cholesterol
     • Deep dive: The 9 things that matter most for your cholesterol

854. soedamahmuthu2011milk

     S. S. Soedamah-Muthu et al. Milk and dairy consumption and incidence of cardiovascular diseases and all-cause mortality: dose-response meta-analysis of prospective cohort studies. Am J Clin Nutr, 93(1):158-71, 2011. doi:10.3945/ajcn.2010.29866 Evidence: High

     Verified 2026-10-01 · PMID 21068345 · DOI 10.3945/ajcn.2010.29866

     • Wiki: Milk

855. soga2017gardening

     M. Soga, K. J. Gaston, and Y. Yamaura. Gardening is beneficial for health: A meta-analysis. Preventive Medicine Reports, 5:92-99, 2017. doi:10.1016/j.pmedr.2016.11.007 Evidence: Low

     Verified 2026-09-27 · PMID 27981022 · DOI 10.1016/j.pmedr.2016.11.007

     • Deep dive: Does having a pet actually help you live longer?

856. soh2020digitalcbt

     H. L. Soh et al. Efficacy of digital cognitive behavioural therapy for insomnia: a meta-analysis of randomised controlled trials. Sleep Med, 75:315-325, 2020. doi:10.1016/j.sleep.2020.08.020 Evidence: Moderate

     Verified 2026-09-26 · PMID 32950013 · DOI 10.1016/j.sleep.2020.08.020

     • What Matters: What actually moves sleep quality
     • Deep dive: Top 10 insomnia remedies, ranked by the evidence
     • What Matters: The healthiest habits, ranked

857. sommerlad2019whitehallii

     A. Sommerlad et al. Association of social contact with dementia and cognition: 28-year follow-up of the Whitehall II cohort study. PLoS Med, 16(8):e1002862, 2019. doi:10.1371/journal.pmed.1002862 Evidence: Low

     Verified 2026-09-26 · DOI 10.1371/journal.pmed.1002862

     • What Matters: What raises dementia risk most
     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • What Matters: Factors behind Alzheimer’s death risk
     • What Matters: The healthiest habits, ranked

858. song2026passivesmoking

     Y. Song, K. Du, and H. Jiang. Passive smoking and the risk of hypertension in nonsmoking adults: a systematic review and meta-analysis. PeerJ, 14:e20639, 2026. doi:10.7717/peerj.20639 Evidence: Moderate

     Verified 2026-09-26 · PMID 41551450 · DOI 10.7717/peerj.20639

     • What Matters: Levers on hypertensive disease deaths

859. sordo2017opioidsubstitution

     L. Sordo et al. Mortality risk during and after opioid substitution treatment: systematic review and meta-analysis of cohort studies. BMJ, 357:j1550, 2017. doi:10.1136/bmj.j1550 Evidence: High

     Verified 2026-09-28 · PMID 28446428 · DOI 10.1136/bmj.j1550

     • Quiz: Drugs & substances

860. spartano2019associationaccelerometer

     N. L. Spartano et al. Association of Accelerometer-Measured Light-Intensity Physical Activity With Brain Volume: The Framingham Heart Study. JAMA Netw Open, 2(4):e192745, 2019. doi:10.1001/jamanetworkopen.2019.2745 Evidence: Very low

     Verified 2026-09-26 · PMID 31002329 · DOI 10.1001/jamanetworkopen.2019.2745

     • Wiki: Cognitive aging
     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

861. spielman1987behavioral

     A. J. Spielman, L. S. Caruso, and P. B. Glovinsky. A behavioral perspective on insomnia treatment. Psychiatr Clin North Am, 10(4):541-53, 1987. Evidence: Very low

     Verified 2026-09-22 · PMID 3332317

     • Wiki: Insomnia

862. sprint2015intensivevs

     The SPRINT Research Group. A Randomized Trial of Intensive versus Standard Blood-Pressure Control. N Engl J Med, 373(22):2103-2116, 2015. doi:10.1056/NEJMoa1511939 Evidence: Moderate

     Verified 2026-09-26 · DOI 10.1056/NEJMoa1511939

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Cardiovascular disease
     • Wiki: Blood pressure
     • Deep dive: The 10 things that matter most for your heart
     • Deep dive: Is your blood pressure quietly aging you? The 9 things that matter most
     • Quiz: Blood pressure check

863. sprint2019intensivebp

     SPRINT MIND Investigators for the SPRINT Research Group et al. Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia: A Randomized Clinical Trial. JAMA, 321(6):553-561, 2019. doi:10.1001/jama.2018.21442 Evidence: Moderate

     Verified 2026-09-27 · PMID 30688979 · DOI 10.1001/jama.2018.21442

     • Wiki: Dementia risk factors
     • Wiki: Cognitive aging
     • Wiki: Brain health (section)
     • Deep dive: How to escape dementia: all 14 risk factors, ranked

864. spruill2019highperceived

     T. M. Spruill et al. Association Between High Perceived Stress Over Time and Incident Hypertension in Black Adults: Findings From the Jackson Heart Study. J Am Heart Assoc, 8(21):e012139, 2019. doi:10.1161/JAHA.119.012139 Evidence: Low

     Verified 2026-09-26 · PMID 31615321 · DOI 10.1161/JAHA.119.012139

     • What Matters: Levers on hypertensive disease deaths

865. srikanthan2014musclemass

     P. Srikanthan and A. S. Karlamangla. Muscle mass index as a predictor of longevity in older adults. Am J Med, 127(6):547-53, 2014. doi:10.1016/j.amjmed.2014.02.007 Evidence: Low

     Verified 2026-09-28 · PMID 24561114 · DOI 10.1016/j.amjmed.2014.02.007

     • Wiki: Muscle mass

866. srour2019ultraprocessed

     B. Srour et al. Ultra-processed food intake and risk of cardiovascular disease: prospective cohort study (NutriNet-Santé). BMJ, 365:l1451, 2019. doi:10.1136/bmj.l1451 Evidence: Low

     Verified 2026-09-27 · PMID 31142457 · DOI 10.1136/bmj.l1451

     • Wiki: Metabolic health and type 2 diabetes
     • Deep dive: The 8 things that matter most for your metabolism

867. stamatakis2018selfrated

     E. Stamatakis et al. Self-rated walking pace and all-cause, cardiovascular disease and cancer mortality: individual participant pooled analysis of 50 225 walkers from 11 population British cohorts. Br J Sports Med, 52(12):761-768, 2018. doi:10.1136/bjsports-2017-098677 Evidence: High

     Verified 2026-09-26 · DOI 10.1136/bjsports-2017-098677

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Walking and daily steps
     • What Matters: Movement: What Matters?

868. stamatakis2022vigorousintermittent

     E. Stamatakis et al. Association of wearable device-measured vigorous intermittent lifestyle physical activity with mortality. Nat Med, 28(12):2521-2529, 2022. doi:10.1038/s41591-022-02100-x Evidence: Low

     Verified 2026-09-26 · DOI 10.1038/s41591-022-02100-x

     • Wiki: High-intensity interval training
     • What Matters: Movement: What Matters?

869. stang2016doesskin

     A. Stang and K. H. Jöckel. Does skin cancer screening save lives? A detailed analysis of mortality time trends in Schleswig-Holstein and Germany. Cancer, 122(3):432-7, 2016. doi:10.1002/cncr.29755 Evidence: Very low

     Verified 2026-09-26 · PMID 26480048 · DOI 10.1002/cncr.29755

     • What Matters: Sun and the rest: melanoma death risk

870. statpearlsnafloppyeyelid

     A. Kloosterboer, C. Y. Negron, and T. J. Stokkermans. Floppy Eyelid Syndrome. StatPearls Publishing. Evidence: Not graded (reference page)

     Verified 2026-09-27

     • Wiki: Skin aging
     • Deep dive: What your eyebags are actually telling you about your health

871. steffener2016differencesbetween

     J. Steffener et al. Differences between chronological and brain age are related to education and self-reported physical activity. Neurobiol Aging, 40:138-144, 2016. doi:10.1016/j.neurobiolaging.2016.01.014 Evidence: Very low

     Verified 2026-09-26 · PMID 26973113 · DOI 10.1016/j.neurobiolaging.2016.01.014

     • Wiki: Cognitive aging
     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

872. stensvold2020generation100

     D. Stensvold et al. Effect of exercise training for five years on all cause mortality in older adults-the Generation 100 study: randomised controlled trial. BMJ, 371:m3485, 2020. doi:10.1136/bmj.m3485 Evidence: Low

     Verified 2026-09-28 · PMID 33028588 · DOI 10.1136/bmj.m3485

     • Wiki: Exercise and longevity
     • Wiki: VO2 max
     • Wiki: Zone 2 training
     • Wiki: High-intensity interval training
     • Wiki: Exercise (section)
     • Wiki: Cardio and aerobic fitness (section)

873. stepien2016softdrinks

     M. Stepien et al. Consumption of soft drinks and juices and risk of liver and biliary tract cancers in a European cohort. Eur J Nutr, 55(1):7-20, 2016. doi:10.1007/s00394-014-0818-5 Evidence: Low

     Verified 2026-09-26 · PMID 25528243 · DOI 10.1007/s00394-014-0818-5

     • What Matters: Habits behind liver cancer death risk

874. steptoe2013socialisolation

     A. Steptoe et al. Social isolation, loneliness, and all-cause mortality in older men and women. Proc Natl Acad Sci U S A, 110(15):5797-5801, 2013. doi:10.1073/pnas.1219686110 Evidence: Low

     Verified 2026-09-26 · DOI 10.1073/pnas.1219686110

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Social connection
     • Deep dive: The 8 things that matter most for connection and purpose
     • Quiz: Social life

875. stevenson2018natureworking

     M. P. Stevenson, T. Schilhab, and P. Bentsen. Attention Restoration Theory II: a systematic review to clarify attention processes affected by exposure to natural environments. J Toxicol Environ Health B Crit Rev, 21(4):227-268, 2018. doi:10.1080/10937404.2018.1505571 Evidence: Moderate

     Verified 2026-09-26 · DOI 10.1080/10937404.2018.1505571

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • What Matters: What stretches, or shreds, attention

876. stockwell2016domoderate

     T. Stockwell et al. Do "Moderate" Drinkers Have Reduced Mortality Risk? A Systematic Review and Meta-Analysis of Alcohol Consumption and All-Cause Mortality. J Stud Alcohol Drugs, 77(2):185-98, 2016. doi:10.15288/jsad.2016.77.185 Evidence: High

     Verified 2026-09-26 · PMID 26997174 · DOI 10.15288/jsad.2016.77.185

     • Wiki: Alcohol
     • What Matters: Habits that change cancer death risk
     • What Matters: What moves blood-cancer death risk
     • What Matters: What raises — or cuts — stroke death risk

877. stomach2021familyhistory

     F. Vitelli-Storelli et al. Family History and Gastric Cancer Risk: A Pooled Investigation in the Stomach Cancer Pooling (STOP) Project Consortium. Cancers (Basel), 13(15), 2021. doi:10.3390/cancers13153844 Evidence: High

     Verified 2026-09-26 · PMID 34359744 · DOI 10.3390/cancers13153844

     • Wiki: Helicobacter pylori
     • Deep dive: H. pylori and stomach cancer: what the evidence shows
     • What Matters: What raises stomach cancer death risk

878. stonge2016dietcomposition

     M. P. St-Onge et al. Fiber and Saturated Fat Are Associated with Sleep Arousals and Slow Wave Sleep. J Clin Sleep Med, 12(1):19-24, 2016. doi:10.5664/jcsm.5384 Evidence: Very low

     Verified 2026-09-26 · PMID 26156950 · DOI 10.5664/jcsm.5384

     • What Matters: What actually moves sleep quality
     • Deep dive: What matters most for high-quality sleep

879. stothart2015notificationssustained

     C. Stothart, A. Mitchum, and C. Yehnert. The attentional cost of receiving a cell phone notification. J Exp Psychol Hum Percept Perform, 41(4):893-897, 2015. doi:10.1037/xhp0000100 Evidence: Very low

     Verified 2026-09-26 · DOI 10.1037/xhp0000100

     • What Matters: What stretches, or shreds, attention

880. stough2005androgeneticalopecia

     D. Stough et al. Psychological effect, pathophysiology, and management of androgenetic alopecia in men. Mayo Clin Proc, 80(10):1316-1322, 2005. doi:10.4065/80.10.1316 Evidence: Not graded (review)

     Verified 2026-09-29 · PMID 16212145 · DOI 10.4065/80.10.1316

     • Wiki: Hair loss

881. strak2021airpollution

     M. Strak et al. Long term exposure to low level air pollution and mortality in eight European cohorts within the ELAPSE project: pooled analysis. BMJ, 374:n1904, 2021. doi:10.1136/bmj.n1904 Evidence: High

     Verified 2026-09-26 · PMID 34470785 · DOI 10.1136/bmj.n1904

     • What Matters: Factors that swing COPD deaths

882. stratton1998familyhistory

     J. F. Stratton et al. A systematic review and meta-analysis of family history and risk of ovarian cancer. Br J Obstet Gynaecol, 105(5):493-9, 1998. doi:10.1111/j.1471-0528.1998.tb10148.x Evidence: High

     Verified 2026-09-26 · PMID 9637117 · DOI 10.1111/j.1471-0528.1998.tb10148.x

     • What Matters: What raises ovarian cancer death risk

883. strazzullo2010excessbody

     P. Strazzullo et al. Excess body weight and incidence of stroke: meta-analysis of prospective studies with 2 million participants. Stroke, 41(5):e418-26, 2010. doi:10.1161/STROKEAHA.109.576967 Evidence: High

     Verified 2026-09-26 · PMID 20299666 · DOI 10.1161/STROKEAHA.109.576967

     • What Matters: What raises — or cuts — stroke death risk

884. studdert2020handgunsuicide

     D. M. Studdert et al. Handgun Ownership and Suicide in California. N Engl J Med, 382(23):2220-2229, 2020. doi:10.1056/NEJMsa1916744 Evidence: Low

     Verified 2026-09-26 · PMID 32492303 · DOI 10.1056/NEJMsa1916744

     Metadata confirmed against the Europe PMC MEDLINE record for this PMID (NCBI E-utilities unavailable 2026-09-26).

     • What Matters: Factors linked to suicide deaths

885. studenski2011gaitspeed

     S. Studenski et al. Gait speed and survival in older adults. JAMA, 305(1):50-8, 2011. doi:10.1001/jama.2010.1923 Evidence: High

     Verified 2026-09-28 · PMID 21205966 · DOI 10.1001/jama.2010.1923

     • Wiki: Functional fitness

886. stutz2019eveningexercise

     J. Stutz, R. Eiholzer, and C. M. Spengler. Effects of Evening Exercise on Sleep in Healthy Participants: A Systematic Review and Meta-Analysis. Sports Med, 49(2):269-287, 2019. doi:10.1007/s40279-018-1015-0 Evidence: Moderate

     Verified 2026-09-26 · PMID 30374942 · DOI 10.1007/s40279-018-1015-0

     • Wiki: Sleep quality
     • What Matters: What actually moves sleep quality
     • Deep dive: What matters most for high-quality sleep
     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

887. su2022leisureactivities

     S. Su et al. Leisure Activities and the Risk of Dementia. Neurology, 99(15), 2022. doi:10.1212/WNL.0000000000200929 Evidence: High

     Verified 2026-09-26 · DOI 10.1212/WNL.0000000000200929

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • What Matters: What raises dementia risk most
     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • What Matters: Factors behind Alzheimer’s death risk
     • What Matters: The healthiest habits, ranked

888. suez2022nnsmicrobiome

     J. Suez et al. Personalized microbiome-driven effects of non-nutritive sweeteners on human glucose tolerance. Cell, 185(18):3307-3328.e19, 2022. doi:10.1016/j.cell.2022.07.016 Evidence: Low

     Verified 2026-10-05 · PMID 35987213 · DOI 10.1016/j.cell.2022.07.016

     • Deep dive: Diet soda vs regular soda vs water: what the evidence shows

889. sun2019fried

     Y. Sun et al. Association of fried food consumption with all cause, cardiovascular, and cancer mortality: prospective cohort study. BMJ, 364:k5420, 2019. doi:10.1136/bmj.k5420 Evidence: Low

     Verified 2026-10-01 · PMID 30674467 · DOI 10.1136/bmj.k5420

     • Wiki: Fried foods

890. sun2023chocolate

     Y. Sun et al. Chocolate Consumption in Relation to All-Cause and Cause-Specific Mortality in Women: The Women's Health Initiative. J Acad Nutr Diet, 123(6):902-911.e3, 2023. doi:10.1016/j.jand.2022.12.007 Evidence: Low

     Verified 2026-10-01 · PMID 36549566 · DOI 10.1016/j.jand.2022.12.007

     • Wiki: Chocolate
     • What Matters: Foods ranked for longevity

891. sun2023remainder

     J. Sun et al. Association of the American Heart Association's new "Life's Essential 8" with all-cause and cardiovascular disease-specific mortality: prospective cohort study. BMC Med, 21(1):116, 2023. doi:10.1186/s12916-023-02824-8 Evidence: Low

     Verified 2026-09-26 · PMID 36978123 · DOI 10.1186/s12916-023-02824-8

     • Wiki: Sleep duration and mortality
     • What Matters: What sleep does to how long you live
     • Deep dive: How sleep affects how long you live

892. sundelin2013cuesfatigue

     T. Sundelin et al. Cues of fatigue: effects of sleep deprivation on facial appearance. Sleep, 36(9):1355-60, 2013. doi:10.5665/sleep.2964 Evidence: Very low

     Verified 2026-09-26 · PMID 23997369 · DOI 10.5665/sleep.2964

     • Wiki: Skin aging
     • Deep dive: What your eyebags are actually telling you about your health

893. sung2016breastfeedingduration

     H. K. Sung et al. The Effect of Breastfeeding Duration and Parity on the Risk of Epithelial Ovarian Cancer: A Systematic Review and Meta-analysis. J Prev Med Public Health, 49(6):349-366, 2016. doi:10.3961/jpmph.16.066 Evidence: High

     Verified 2026-09-26 · PMID 27951628 · DOI 10.3961/jpmph.16.066

     • What Matters: What raises ovarian cancer death risk

894. sutcliffe2000ovarianbreast

     S. Sutcliffe et al. Ovarian and breast cancer risks to women in families with two or more cases of ovarian cancer. Int J Cancer, 87(1):110-7, 2000. doi:10.1002/1097-0215(20000701)87:1<110::aid-ijc16>3.0.co;2-6 Evidence: Low

     Verified 2026-09-26 · PMID 10861460 · DOI 10.1002/1097-0215(20000701)87:1<110::aid-ijc16>3.0.co;2-6

     • What Matters: What raises ovarian cancer death risk

895. sutin2023meaninglife

     D. A. R. Sutin et al. Sense of meaning and purpose in life and risk of incident dementia: New data and meta-analysis. Arch Gerontol Geriatr, 105:104847, 2023. doi:10.1016/j.archger.2022.104847 Evidence: High

     Verified 2026-09-26 · PMID 36347158 · DOI 10.1016/j.archger.2022.104847

     • What Matters: What raises dementia risk most
     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • What Matters: Factors behind Alzheimer’s death risk
     • What Matters: The healthiest habits, ranked

896. sutton2018earlytime

     E. F. Sutton et al. Early Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress Even without Weight Loss in Men with Prediabetes. Cell Metab, 27(6):1212-1221.e3, 2018. doi:10.1016/j.cmet.2018.04.010 Evidence: Low

     Verified 2026-09-26 · DOI 10.1016/j.cmet.2018.04.010

     • Wiki: Meal timing
     • Deep dive: Does an early last meal actually help you live longer?

897. swaminathan2021pure

     S. Swaminathan et al. Associations of cereal grains intake with cardiovascular disease and mortality across 21 countries in Prospective Urban and Rural Epidemiology study: prospective cohort study. BMJ, 372:m4948, 2021. doi:10.1136/bmj.m4948 Evidence: Moderate

     Verified 2026-10-01 · PMID 33536317 · DOI 10.1136/bmj.m4948

     • Wiki: White rice
     • Wiki: Refined grains
     • What Matters: Foods ranked for longevity

898. syn2021metabolicbariatric

     N. L. Syn et al. Association of metabolic-bariatric surgery with long-term survival in adults with and without diabetes: a one-stage meta-analysis of matched cohort and prospective controlled studies with 174 772 participants. Lancet, 397(10287):1830-1841, 2021. doi:10.1016/S0140-6736(21)00591-2 Evidence: High

     Verified 2026-09-26 · PMID 33965067 · DOI 10.1016/S0140-6736(21)00591-2

     • Wiki: Body weight
     • Deep dive: How much is the extra weight actually costing you?
     • Quiz: Weight check

899. szalma2011noiseperformance

     J. L. Szalma and P. A. Hancock. Noise effects on human performance: a meta-analytic synthesis. Psychol Bull, 137(4):682-707, 2011. doi:10.1037/a0023987 Evidence: Moderate

     Verified 2026-09-27 · PMID 21707130 · DOI 10.1037/a0023987

     • What Matters: What stretches, or shreds, attention

900. tabak2012prediabetes

     A. G. Tabák et al. Prediabetes: a high-risk state for diabetes development. Lancet, 379(9833):2279-90, 2012. doi:10.1016/S0140-6736(12)60283-9 Evidence: Low

     Verified 2026-09-28 · PMID 22683128 · DOI 10.1016/S0140-6736(12)60283-9

     • Quiz: Metabolic health

901. tai2024bloodpressure

     Y. Tai et al. Blood pressure, pulse rate, and skin temperature during hot-water bathing in real-world settings among community-dwelling older adults: the HEIJO-KYO Study. Environ Health Prev Med, 29:12, 2024. doi:10.1265/ehpm.23-00320 Evidence: Very low

     Verified 2026-09-27 · PMID 38447972 · DOI 10.1265/ehpm.23-00320

     • Wiki: Heat exposure
     • Deep dive: Are hot tubs good for your health and longevity?

902. tamminga2016methylphenidatesustained

     H. G. H. Tamminga et al. Effects of methylphenidate on executive functioning in attention-deficit/hyperactivity disorder across the lifespan: a meta-regression analysis. Psychol Med, 46(9):1791-1807, 2016. doi:10.1017/S0033291716000350 Evidence: Moderate

     Verified 2026-09-26 · DOI 10.1017/S0033291716000350

     • What Matters: What stretches, or shreds, attention

903. tan2012redblood

     Z. S. Tan et al. Red blood cell ω-3 fatty acid levels and markers of accelerated brain aging. Neurology, 78(9):658-64, 2012. doi:10.1212/wnl.0b013e318249f6a9 Evidence: Very low

     Verified 2026-09-27 · PMID 22371413 · DOI 10.1212/wnl.0b013e318249f6a9

     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • Deep dive: Plants and your brain: what the vegetarian, Mediterranean and MIND studies really show about dementia
     • What Matters: The healthiest habits, ranked

904. tan2021obstructivesleep

     N. K. W. Tan et al. The association of obstructive sleep apnea with melanoma incidence and mortality: a meta-analysis of 5,276,451 patients. Sleep Med, 88:213-220, 2021. doi:10.1016/j.sleep.2021.10.027 Evidence: Low

     Verified 2026-09-26 · PMID 34794048 · DOI 10.1016/j.sleep.2021.10.027

     • What Matters: Sun and the rest: melanoma death risk

905. tan2022bmitrajectory

     L. Tan et al. Association of body mass index trajectory and hypertension risk: A systematic review of cohort studies and network meta-analysis of 89,094 participants. Front Cardiovasc Med, 9:941341, 2022. doi:10.3389/fcvm.2022.941341 Evidence: Very low

     Verified 2026-09-27 · PMID 36684600 · DOI 10.3389/fcvm.2022.941341

     • What Matters: Levers on hypertensive disease deaths

906. tang2015tea

     J. Tang et al. Tea consumption and mortality of all cancers, CVD and all causes: a meta-analysis of eighteen prospective cohort studies. Br J Nutr, 114(5):673-83, 2015. doi:10.1017/S0007114515002329 Evidence: High

     Verified 2026-10-01 · PMID 26202661 · DOI 10.1017/S0007114515002329

     • Wiki: Tea

907. tang2021suppertiming

     J. Tang et al. Supper Timing and Cardiovascular Mortality: The Japan Collaborative Cohort Study. Nutrients, 13(10):3389, 2021. doi:10.3390/nu13103389 Evidence: Low

     Verified 2026-09-26 · DOI 10.3390/nu13103389

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Meal timing
     • Deep dive: Does an early last meal actually help you live longer?

908. taniguchi2024petmortality

     Y. Taniguchi, T. Ikeuchi, and J. Yong. Dog, cat, bird, fish, and other pet ownership and mortality: Evidence from the HILDA cohort. PLOS ONE, 19(8):e0305546, 2024. doi:10.1371/journal.pone.0305546 Evidence: Low

     Verified 2026-09-27 · PMID 39141654 · DOI 10.1371/journal.pone.0305546

     • Wiki: Pet ownership
     • Deep dive: Does having a pet actually help you live longer?
     • What Matters: What Affects Lifespan the Most

909. taquet2024recombinantshingles

     M. Taquet et al. The recombinant shingles vaccine is associated with lower risk of dementia. Nat Med, 30(10):2777-2781, 2024. doi:10.1038/s41591-024-03201-5 Evidence: Low

     Verified 2026-09-27 · PMID 39053634 · DOI 10.1038/s41591-024-03201-5

     • What Matters: What raises dementia risk most
     • Deep dive: How to escape dementia: all 14 risk factors, ranked
     • What Matters: Factors behind Alzheimer’s death risk
     • What Matters: The healthiest habits, ranked

910. tardif2019colcot

     J. C. Tardif et al. Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction. N Engl J Med, 381(26):2497-2505, 2019. doi:10.1056/NEJMoa1912388 Evidence: Moderate

     Verified 2026-09-28 · PMID 31733140 · DOI 10.1056/NEJMoa1912388

     • Wiki: Inflammation and aging

911. tate2012choice

     D. F. Tate et al. Replacing caloric beverages with water or diet beverages for weight loss in adults: main results of the Choose Healthy Options Consciously Everyday (CHOICE) randomized clinical trial. Am J Clin Nutr, 95(3):555-63, 2012. doi:10.3945/ajcn.111.026278 Evidence: Moderate

     Verified 2026-10-05 · PMID 22301929 · DOI 10.3945/ajcn.111.026278

     • Deep dive: Diet soda vs regular soda vs water: what the evidence shows

912. taylor2010alcoholinjury

     B. Taylor et al. The more you drink, the harder you fall: a systematic review and meta-analysis of how acute alcohol consumption and injury or collision risk increase together. Drug Alcohol Depend, 110(1-2):108-16, 2010. doi:10.1016/j.drugalcdep.2010.02.011 Evidence: Moderate

     Verified 2026-09-26 · PMID 20236774 · DOI 10.1016/j.drugalcdep.2010.02.011

     • Wiki: Alcohol
     • What Matters: Factors that swing accidental deaths

913. taylor2014smokingcessation

     G. Taylor et al. Change in mental health after smoking cessation: systematic review and meta-analysis. BMJ, 348:g1151, 2014. doi:10.1136/bmj.g1151 Evidence: High

     Verified 2026-09-26 · PMID 24524926 · DOI 10.1136/bmj.g1151

     • Wiki: Smoking
     • Wiki: Mental health conditions and lifespan
     • Deep dive: The mental health conditions that cost the most years, ranked

914. tefft2016acutesleep

     B. C. Tefft. Acute Sleep Deprivation and Risk of Motor Vehicle Crash Involvement. AAA Foundation for Traffic Safety (Technical Report), 2016. Evidence: Low

     Verified 2026-09-27

     • Wiki: Road safety
     • Deep dive: The 9 things that matter most for surviving the road

915. tefft2018sleepdeprivation

     B. C. Tefft. Acute sleep deprivation and culpable motor vehicle crash involvement. Sleep, 41(10):zsy144, 2018. doi:10.1093/sleep/zsy144 Evidence: Low

     Verified 2026-09-26 · PMID 30239905 · DOI 10.1093/sleep/zsy144

     Sleep uses an article number (zsy144) in place of page numbers.

     • Wiki: Road safety
     • What Matters: Factors that swing accidental deaths

916. teshima2026cigarettesmoking

     A. Teshima et al. Evaluating the effect of cigarettes smoking on oesophageal cancer risk: a systematic review and meta-analysis with dose-response relationships. Eur J Public Health, 36(4), 2026. doi:10.1093/eurpub/ckag123 Evidence: High

     Verified 2026-09-26 · PMID 42533755 · DOI 10.1093/eurpub/ckag123

     • What Matters: Factors that swing esophageal cancer deaths

917. threapleton2013dietaryfiber

     D. E. Threapleton et al. Dietary fibre intake and risk of cardiovascular disease: systematic review and meta-analysis. BMJ, 347:f6879, 2013. doi:10.1136/bmj.f6879 Evidence: High

     Verified 2026-09-27 · PMID 24355537 · DOI 10.1136/bmj.f6879

     • Wiki: Dietary fiber
     • Deep dive: Why doctors will not shut up about fiber
     • What Matters: Habits that swing heart-disease death risk

918. thun201350year

     M. J. Thun et al. 50-year trends in smoking-related mortality in the United States. N Engl J Med, 368(4):351-64, 2013. doi:10.1056/NEJMsa1211127 Evidence: High

     Verified 2026-09-26 · PMID 23343064 · DOI 10.1056/NEJMsa1211127

     • Wiki: Smoking
     • What Matters: Smoking and the rest: lung cancer death risk
     • What Matters: Factors that swing COPD deaths

919. tian2023alcoholconsumption

     Y. Tian et al. Alcohol consumption and all-cause and cause-specific mortality among US adults: prospective cohort study. BMC Med, 21(1):208, 2023. doi:10.1186/s12916-023-02907-6 Evidence: Low

     Verified 2026-09-26 · PMID 37286970 · DOI 10.1186/s12916-023-02907-6

     • What Matters: What moves diabetes death odds

920. tiihonen2009antipsychoticuse

     J. Tiihonen et al. 11-year follow-up of mortality in patients with schizophrenia: a population-based cohort study (FIN11 study). Lancet, 374(9690):620-7, 2009. doi:10.1016/S0140-6736(09)60742-X Evidence: Low

     Verified 2026-09-26 · PMID 19595447 · DOI 10.1016/S0140-6736(09)60742-X

     • Wiki: Mental health conditions and lifespan
     • Deep dive: The mental health conditions that cost the most years, ranked
     • Quiz: Mental wellbeing

921. toews2019nss

     I. Toews et al. Association between intake of non-sugar sweeteners and health outcomes: systematic review and meta-analyses of randomised and non-randomised controlled trials and observational studies. BMJ, 364:k4718, 2019. doi:10.1136/bmj.k4718 Evidence: Low

     Verified 2026-10-05 · PMID 30602577 · DOI 10.1136/bmj.k4718

     • Deep dive: Diet soda vs regular soda vs water: what the evidence shows

922. tonetti2007treatmentperiodontitis

     M. S. Tonetti et al. Treatment of Periodontitis and Endothelial Function. N Engl J Med, 356(9):911-920, 2007. doi:10.1056/NEJMoa063186 Evidence: Low

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Oral health
     • Wiki: Digestive and oral health (section)
     • Deep dive: Does oral care actually affect how long you live?

923. tong2017cheeseINCOMPLETE METADATA

     X. Tong et al. Cheese Consumption and Risk of All-Cause Mortality: A Meta-Analysis of Prospective Studies. Nutrients, 9(1), 2017. doi:10.3390/nu9010063 Evidence: High

     Verified 2026-10-01 · PMID 28098767 · DOI 10.3390/nu9010063

     PubMed lists no pages for this paper yet (checked 2026-10-01).

     • Wiki: Cheese

924. tong2019risksischaemic

     T. Y. N. Tong et al. Risks of ischaemic heart disease and stroke in meat eaters, fish eaters, and vegetarians over 18 years of follow-up: results from the prospective EPIC-Oxford study. BMJ, 366:l4897, 2019. doi:10.1136/bmj.l4897 Evidence: Low

     Verified 2026-09-26 · PMID 31484644 · DOI 10.1136/bmj.l4897

     • Deep dive: Plants and your brain: what the vegetarian, Mediterranean and MIND studies really show about dementia

925. tong2020vegetarianvegan

     T. Y. N. Tong et al. Vegetarian and vegan diets and risks of total and site-specific fractures: results from the prospective EPIC-Oxford study. BMC Med, 18(1), 2020. doi:10.1186/s12916-020-01815-3 Evidence: Low

     Verified 2026-09-26 · DOI 10.1186/s12916-020-01815-3

     • Wiki: Dietary patterns
     • Deep dive: Vegan, vegetarian, omnivore, carnivore: what the labels actually buy you

926. tramacere2012alcoholdrinking

     I. Tramacere et al. A meta-analysis on alcohol drinking and gastric cancer risk. Ann Oncol, 23(1):28-36, 2012. doi:10.1093/annonc/mdr135 Evidence: High

     Verified 2026-09-26 · PMID 21536659 · DOI 10.1093/annonc/mdr135

     • What Matters: What raises stomach cancer death risk

927. tramacere2012alcoholdrinking2

     I. Tramacere et al. Alcohol drinking and non-Hodgkin lymphoma risk: a systematic review and a meta-analysis. Ann Oncol, 23(11):2791-2798, 2012. doi:10.1093/annonc/mds013 Evidence: Moderate

     Verified 2026-09-26 · PMID 22357444 · DOI 10.1093/annonc/mds013

     • What Matters: What moves blood-cancer death risk

928. trauer2015cbti

     J. M. Trauer et al. Cognitive Behavioral Therapy for Chronic Insomnia: A Systematic Review and Meta-analysis. Ann Intern Med, 163(3):191-204, 2015. doi:10.7326/M14-2841 Evidence: High

     Verified 2026-09-26 · PMID 26054060 · DOI 10.7326/M14-2841

     • Wiki: Insomnia
     • Wiki: Sleep quality
     • What Matters: What actually moves sleep quality
     • Deep dive: What matters most for high-quality sleep
     • Deep dive: Bryan Johnson's Ten Sleep Power Laws: what each one asks and how strong the evidence is
     • Deep dive: Top 10 insomnia remedies, ranked by the evidence
     • What Matters: The healthiest habits, ranked

929. travis1995bladderkidney

     L. B. Travis et al. Bladder and kidney cancer following cyclophosphamide therapy for non-Hodgkin's lymphoma. J Natl Cancer Inst, 87(7):524-30, 1995. doi:10.1093/jnci/87.7.524 Evidence: Low

     Verified 2026-09-26 · PMID 7707439 · DOI 10.1093/jnci/87.7.524

     • What Matters: What changes bladder cancer death risk

930. tregear2010cpapcrash

     S. Tregear et al. Continuous positive airway pressure reduces risk of motor vehicle crash among drivers with obstructive sleep apnea: systematic review and meta-analysis. Sleep, 33(10):1373-80, 2010. doi:10.1093/sleep/33.10.1373 Evidence: Moderate

     Verified 2026-09-26 · PMID 21061860 · DOI 10.1093/sleep/33.10.1373

     • What Matters: Factors that swing accidental deaths

931. tremain2023inversevaccine

     A. C. Tremain et al. Synthetically glycosylated antigens for the antigen-specific suppression of established immune responses. Nat Biomed Eng, 7(9):1142-1155, 2023. doi:10.1038/s41551-023-01086-2 Evidence: Very low

     Verified 2026-09-27 · PMID 37679570 · DOI 10.1038/s41551-023-01086-2

     • Deep dive: The 9 things that matter most for taming inflammation

932. tsai2015pacedbreathing

     H. J. Tsai et al. Efficacy of paced breathing for insomnia: enhances vagal activity and improves sleep quality. Psychophysiology, 52(3):388-96, 2015. doi:10.1111/psyp.12333 Evidence: Very low

     Verified 2026-10-08 · PMID 25234581 · DOI 10.1111/psyp.12333

     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

933. tsai2022taiwanesevegetarians

     J. H. Tsai et al. Taiwanese Vegetarians Are Associated with Lower Dementia Risk: A Prospective Cohort Study. Nutrients, 14(3):588, 2022. doi:10.3390/nu14030588 Evidence: Low

     Verified 2026-09-27 · PMID 35276947 · DOI 10.3390/nu14030588

     • Wiki: Dementia risk factors
     • Deep dive: Plants and your brain: what the vegetarian, Mediterranean and MIND studies really show about dementia

934. tudorlocke2019cadence

     C. Tudor-Locke et al. Walking cadence (steps/min) and intensity in 21-40 year olds: CADENCE-adults. Int J Behav Nutr Phys Act, 16(1):8, 2019. doi:10.1186/s12966-019-0769-6 Evidence: Very low

     Verified 2026-09-28 · PMID 30654810 · DOI 10.1186/s12966-019-0769-6

     • Wiki: VO2 max
     • Wiki: Zone 2 training
     • Wiki: High-intensity interval training
     • Wiki: Walking and daily steps

935. turati2012familyhistory

     F. Turati et al. Family history of liver cancer and hepatocellular carcinoma. Hepatology, 55(5):1416-25, 2012. doi:10.1002/hep.24794 Evidence: High

     Verified 2026-09-26 · PMID 22095619 · DOI 10.1002/hep.24794

     • What Matters: Habits behind liver cancer death risk

936. turati2013bodymass

     F. Turati et al. A meta-analysis of body mass index and esophageal and gastric cardia adenocarcinoma. Ann Oncol, 24(3):609-17, 2013. doi:10.1093/annonc/mds244 Evidence: High

     Verified 2026-09-26 · PMID 22898040 · DOI 10.1093/annonc/mds244

     • What Matters: Factors that swing esophageal cancer deaths

937. tutunchi2023yogurt

     H. Tutunchi et al. Yogurt consumption and risk of mortality from all causes, CVD and cancer: a comprehensive systematic review and dose-response meta-analysis of cohort studies. Public Health Nutr, 26(6):1196-1209, 2023. doi:10.1017/S1368980022002385 Evidence: Moderate

     Verified 2026-10-01 · PMID 36349966 · DOI 10.1017/S1368980022002385

     • Wiki: Yogurt
     • What Matters: Foods ranked for longevity

938. twohigbennett2018healthbenefits

     C. Twohig-Bennett and A. Jones. The health benefits of the great outdoors: A systematic review and meta-analysis of greenspace exposure and health outcomes. Environ Res, 166:628-637, 2018. doi:10.1016/j.envres.2018.06.030 Evidence: Low

     Verified 2026-09-26 · DOI 10.1016/j.envres.2018.06.030

     • Wiki: Stress and anxiety
     • Wiki: Green space
     • Deep dive: The 8 things that matter most for staying calm
     • Deep dive: Does living somewhere green actually help you live longer?

939. uemura2001helicobacterpylori

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     • Wiki: Helicobacter pylori
     • Deep dive: H. pylori and stomach cancer: what the evidence shows

940. uk2016ukchief

     UK Chief Medical Officers. Alcohol consumption: advice on low risk drinking. UK Government (GOV.UK), 2016. Evidence: Not graded (guideline)

     Verified 2026-09-27

     Original URL was dead (404); replaced with the correct current URL for the same page, confirmed live.

     • Wiki: Alcohol
     • Deep dive: The 7 things to know about alcohol

941. ukai2020habitualtub

     T. Ukai et al. Habitual tub bathing and risks of incident coronary heart disease and stroke. Heart, 106(10):732-737, 2020. doi:10.1136/heartjnl-2019-315752 Evidence: Very low

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     • Wiki: Heat exposure
     • Deep dive: Does the sauna actually make you live longer?
     • Deep dive: Are hot tubs good for your health and longevity?
     • What Matters: What Affects Lifespan the Most

942. us2006healthconsequences

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     Verified 2026-09-26

     • Deep dive: Smoking takes about ten years. Here is what quitting gives back
     • What Matters: Smoking and the rest: lung cancer death risk

943. us2014healthconsequences

     US Surgeon General. The health consequences of smoking: 50 years of progress. US Surgeon General, 2014. Evidence: Not graded (guideline)

     Verified 2026-09-26

     • Deep dive: The 9 factors that decide your type 2 diabetes risk
     • Deep dive: Smoking takes about ten years. Here is what quitting gives back
     • Quiz: Smoking
     • Quiz: Smoking check

944. usfa2023residentialfires

     U.S. Fire Administration. Residential fire estimate summaries (2014-2023). U.S. Fire Administration, FEMA, 2023. Evidence: Not graded (statistics)

     Verified 2026-09-26

     2023 national estimates for residential building fires: 344,600 fires and 2,890 deaths.

     • What Matters: Factors that swing accidental deaths

945. uspstf2021screeningcolorectal

     US Preventive Services Task Force et al. Screening for Colorectal Cancer: US Preventive Services Task Force Recommendation Statement. JAMA, 325(19):1965-1977, 2021. doi:10.1001/jama.2021.6238 Evidence: Not graded (guideline)

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     • Wiki: Colon health
     • Deep dive: The 9 things that matter most for your colon

946. uspstf2021screeninglung

     USPSTF. Lung Cancer: Screening. USPSTF, 2021. Evidence: Not graded (guideline)

     Verified 2026-09-27

     • Wiki: Smoking
     • Deep dive: Smoking takes about ten years. Here is what quitting gives back

947. uspstf2021screeningprediabetes

     USPSTF. Prediabetes and Type 2 Diabetes: Screening. USPSTF, 2021. Evidence: Not graded (guideline)

     Verified 2026-09-27

     • Wiki: Metabolic health and type 2 diabetes
     • Wiki: Body weight
     • Deep dive: The 9 factors that decide your type 2 diabetes risk

948. uspstf2022vitaminmineral

     USPSTF. Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: Preventive Medication. USPSTF, 2022. Evidence: Not graded (guideline)

     Verified 2026-09-27

     Original URL was dead (404); replaced with the correct current URL for the same page, confirmed live.

     • Wiki: Dietary patterns
     • Deep dive: The 8 things that matter most on your plate

949. uspstf2024falls

     US Preventive Services Task Force et al. Interventions to Prevent Falls in Community-Dwelling Older Adults: US Preventive Services Task Force Recommendation Statement. JAMA, 332(1):51-57, 2024. doi:10.1001/jama.2024.8481 Evidence: Not graded (guideline)

     Verified 2026-09-28 · PMID 38833246 · DOI 10.1001/jama.2024.8481

     • Wiki: Balance training
     • Wiki: Fall prevention
     • Wiki: Balance, mobility and function (section)

950. valisoltani2023fiberintake

     N. Valisoltani et al. Fiber intake and risk of chronic obstructive pulmonary disease: A systematic review and dose response meta-analysis. Food Sci Nutr, 11(11):6775-6788, 2023. doi:10.1002/fsn3.3640 Evidence: Low

     Verified 2026-09-26 · PMID 37970426 · DOI 10.1002/fsn3.3640

     • What Matters: Factors that swing COPD deaths

951. vallee2025tobaccosmoking

     A. Vallée. Associations between tobacco smoking and mortality: a sex-stratified cohort analysis. Eur J Public Health, 35(6):1212-1218, 2025. doi:10.1093/eurpub/ckaf194 Evidence: Low

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     • What Matters: Habits that change cancer death risk

952. vallspedret2015mediterraneandiet

     C. Valls-Pedret et al. Mediterranean Diet and Age-Related Cognitive Decline: A Randomized Clinical Trial. JAMA Intern Med, 175(7):1094-1103, 2015. doi:10.1001/jamainternmed.2015.1668 Evidence: Low

     Verified 2026-09-26 · PMID 25961184 · DOI 10.1001/jamainternmed.2015.1668

     • Wiki: Dementia risk factors
     • Deep dive: Plants and your brain: what the vegetarian, Mediterranean and MIND studies really show about dementia

953. valtin2002drinkat

     H. Valtin. "Drink at least eight glasses of water a day." Really? Is there scientific evidence for "8 x 8"?. Am J Physiol Regul Integr Comp Physiol, 283(5):R993-1004, 2002. doi:10.1152/ajpregu.00365.2002 Evidence: Not graded (review)

     Verified 2026-09-26 · PMID 12376390 · DOI 10.1152/ajpregu.00365.2002

     • Wiki: Hydration
     • Deep dive: The 7 things worth knowing about hydration

954. valtorta2016lonelinesssocial

     N. K. Valtorta et al. Loneliness and social isolation as risk factors for coronary heart disease and stroke: systematic review and meta-analysis of longitudinal observational studies. Heart, 102(13):1009-16, 2016. doi:10.1136/heartjnl-2015-308790 Evidence: High

     Verified 2026-09-26 · PMID 27091846 · DOI 10.1136/heartjnl-2015-308790

     • Wiki: Social connection
     • What Matters: Habits that swing heart-disease death risk
     • What Matters: What raises — or cuts — stroke death risk

955. van2000pooledheight

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     • What Matters: What changes breast cancer odds

956. van2000slowwave

     E. Van Cauter. Age-Related Changes in Slow Wave Sleep and REM Sleep and Relationship With Growth Hormone and Cortisol Levels in Healthy Men. JAMA, 284(7):861, 2000. doi:10.1001/jama.284.7.861 Evidence: Very low

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Deep dive: The 9 things that matter most for taming inflammation

957. van2004depressionafter

     J. P. van Melle et al. Prognostic association of depression following myocardial infarction with mortality and cardiovascular events: a meta-analysis. Psychosom Med, 66(6):814-22, 2004. doi:10.1097/01.psy.0000146294.82810.9c Evidence: High

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     • Wiki: Mental health conditions and lifespan
     • Deep dive: What depression does to a lifespan, treated and untreated

958. van2023lecanemabearly

     C. H. van Dyck et al. Lecanemab in Early Alzheimer’s Disease. N Engl J Med, 388(1):9-21, 2023. doi:10.1056/NEJMoa2212948 Evidence: Moderate

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     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Dementia risk factors
     • Deep dive: The 8 things to know about Alzheimer’s risk

959. vandenberg2019ancestorlongevity

     N. van den Berg et al. Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait. Nat Commun, 10(1):35, 2019. doi:10.1038/s41467-018-07925-0 Evidence: Moderate

     Verified 2026-09-26 · PMID 30617297 · DOI 10.1038/s41467-018-07925-0

     • Wiki: Family history and genetics
     • Deep dive: What you inherit from your family, and what you don’t
     • Quiz: Family history
     • Family: How long your ancestors lived

960. vanderweele2016religioussuicide

     T. J. VanderWeele et al. Association Between Religious Service Attendance and Lower Suicide Rates Among US Women. JAMA Psychiatry, 73(8):845-51, 2016. doi:10.1001/jamapsychiatry.2016.1243 Evidence: Low

     Verified 2026-09-26 · PMID 27367927 · DOI 10.1001/jamapsychiatry.2016.1243

     Metadata confirmed against the Europe PMC MEDLINE record for this PMID (NCBI E-utilities unavailable 2026-09-26).

     • What Matters: Factors linked to suicide deaths

961. vanmaanen2016lighttherapy

     A. van Maanen et al. The effects of light therapy on sleep problems: A systematic review and meta-analysis. Sleep Med Rev, 29:52-62, 2016. doi:10.1016/j.smrv.2015.08.009 Evidence: Low

     Verified 2026-10-08 · PMID 26606319 · DOI 10.1016/j.smrv.2015.08.009

     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

962. vanni2025obesityaccelerates

     F. Vanni et al. Obesity accelerates brain ageing: a multimodal imaging study. Brain Commun, 7(6):fcaf389, 2025. doi:10.1093/braincomms/fcaf389 Evidence: Very low

     Verified 2026-09-27 · PMID 41221124 · DOI 10.1093/braincomms/fcaf389

     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years

963. vanstraten2018cbti

     A. van Straten et al. Cognitive and behavioral therapies in the treatment of insomnia: A meta-analysis. Sleep Med Rev, 38:3-16, 2018. doi:10.1016/j.smrv.2017.02.001 Evidence: High

     Verified 2026-09-22 · PMID 28392168 · DOI 10.1016/j.smrv.2017.02.001

     PR #555 audit: the original PMID (28648359) resolved to a different melatonin review; corrected to 28392168.

     • Wiki: Insomnia
     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

964. varraso2007curedmeats

     R. Varraso et al. Prospective study of cured meats consumption and risk of chronic obstructive pulmonary disease in men. Am J Epidemiol, 166(12):1438-45, 2007. doi:10.1093/aje/kwm235 Evidence: Low

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     • What Matters: Factors that swing COPD deaths

965. varraso2015alternatehealthy

     R. Varraso et al. Alternate Healthy Eating Index 2010 and risk of chronic obstructive pulmonary disease among US women and men: prospective study. BMJ, 350:h286, 2015. doi:10.1136/bmj.h286 Evidence: Moderate

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     • What Matters: Factors that swing COPD deaths

966. varraso2019processedmeat

     R. Varraso et al. Processed Meat Intake and Risk of Chronic Obstructive Pulmonary Disease among Middle-aged Women. EClinicalMedicine, 14:88-95, 2019. doi:10.1016/j.eclinm.2019.07.014 Evidence: Low

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     • What Matters: Factors that swing COPD deaths

967. vasilev2018auditorydistraction

     M. R. Vasilev, J. A. Kirkby, and B. Angele. Auditory Distraction During Reading: A Bayesian Meta-Analysis of a Continuing Controversy. Perspect Psychol Sci, 13(5):567-597, 2018. doi:10.1177/1745691617747398 Evidence: Moderate

     Verified 2026-09-26 · DOI 10.1177/1745691617747398

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • What Matters: What stretches, or shreds, attention

968. vertessen2021methylphenidatedose

     K. Vertessen et al. Meta-analysis: Dose-Dependent Effects of Methylphenidate on Neurocognitive Functioning in Children With Attention-Deficit/Hyperactivity Disorder. J Am Acad Child Adolesc Psychiatry, 61(5):626-646, 2021. doi:10.1016/j.jaac.2021.08.023 Evidence: Moderate

     Verified 2026-09-26 · DOI 10.1016/j.jaac.2021.08.023

     • What Matters: What stretches, or shreds, attention

969. vieira2016fruitsvegetables

     A. R. Vieira et al. Fruits, vegetables and lung cancer risk: a systematic review and meta-analysis. Ann Oncol, 27(1):81-96, 2016. doi:10.1093/annonc/mdv381 Evidence: Moderate

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     • What Matters: Smoking and the rest: lung cancer death risk

970. vingelienenawcrfaicr

     S. Vingeliene et al. An update of the WCRF/AICR systematic literature review and meta-analysis on dietary and anthropometric factors and esophageal cancer risk. Ann Oncol, 28(10):2409-2419, 2017. doi:10.1093/annonc/mdx338 Evidence: Moderate

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     • What Matters: Factors that swing esophageal cancer deaths

971. vinogradova2021menopausalhormone

     Y. Vinogradova et al. Use of menopausal hormone therapy and risk of dementia: nested case-control studies using QResearch and CPRD databases. BMJ, 374:n2182, 2021. doi:10.1136/bmj.n2182 Evidence: Low

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     • What Matters: What raises dementia risk most
     • What Matters: Habits that swing heart-disease death risk
     • What Matters: Factors behind Alzheimer’s death risk

972. viola1995apigenin

     H. Viola et al. Apigenin, a component of Matricaria recutita flowers, is a central benzodiazepine receptors-ligand with anxiolytic effects. Planta Med, 61(3):213-216, 1995. doi:10.1055/s-2006-958058 Evidence: Very low

     Verified 2026-09-28 · PMID 7617761 · DOI 10.1055/s-2006-958058

     • Wiki: Apigenin (supplement)

973. viswanathan2005smokingrisk

     A. N. Viswanathan et al. Smoking and the risk of endometrial cancer: results from the Nurses' Health Study. Int J Cancer, 114(6):996-1001, 2005. doi:10.1002/ijc.20821 Evidence: Low

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     • What Matters: Habits that change uterine cancer death risk

974. voight2012hdlmendelian

     B. F. Voight et al. Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet, 380(9841):572-80, 2012. doi:10.1016/S0140-6736(12)60312-2 Evidence: Moderate

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     • Wiki: Cholesterol
     • Deep dive: The 9 things that matter most for your cholesterol

975. vounzoulaki2020gestationaldiabetes

     E. Vounzoulaki et al. Progression to type 2 diabetes in women with a known history of gestational diabetes: systematic review and meta-analysis. BMJ, 369:m1361, 2020. doi:10.1136/bmj.m1361 Evidence: High

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     • Wiki: Metabolic health and type 2 diabetes
     • Deep dive: The 9 factors that decide your type 2 diabetes risk

976. vyas2024multivitamincognitive

     C. M. Vyas et al. Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial and meta-analysis of 3 cognitive studies within COSMOS. Am J Clin Nutr, 119(3):692-701, 2024. doi:10.1016/j.ajcnut.2023.12.011 Evidence: Moderate

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     • Wiki: Cognitive aging
     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

977. walker2006plasticity

     M. P. Walker and R. Stickgold. Sleep, memory, and plasticity. Annu Rev Psychol, 57:139-66, 2006. doi:10.1146/annurev.psych.56.091103.070307 Evidence: Very low

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     PR #555 audit: the original PMID (16318601) resolved to an unrelated paper (Ozer et al., personality prediction); corrected to 16318592.

     • Wiki: Sleep physiology

978. walker2015mentaldisorders

     E. R. Walker, R. E. McGee, and B. G. Druss. Mortality in mental disorders and global disease burden implications: a systematic review and meta-analysis. JAMA Psychiatry, 72(4):334-41, 2015. doi:10.1001/jamapsychiatry.2014.2502 Evidence: High

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     • Wiki: Mental health conditions and lifespan
     • Wiki: Social connection
     • Wiki: Mental health and relationships (section)
     • Deep dive: The 8 things that matter most for connection and purpose
     • Deep dive: The mental health conditions that cost the most years, ranked
     • Deep dive: What depression does to a lifespan, treated and untreated
     • Quiz: Mental wellbeing
     • What Matters: What Affects Lifespan the Most
     • What Matters: The healthiest habits, ranked

979. wan2026fitnessexercise

     L. Wan et al. Fitness and exercise effects on brain age: A randomized clinical trial. J Sport Health Sci, 15:101079, 2026. doi:10.1016/j.jshs.2025.101079 Evidence: Low

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     • Wiki: Cognitive aging
     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

980. wang2007familyhistory

     S. S. Wang et al. Family history of hematopoietic malignancies and risk of non-Hodgkin lymphoma (NHL): a pooled analysis of 10 211 cases and 11 905 controls from the International Lymphoma Epidemiology Consortium (InterLymph). Blood, 109(8):3479-88, 2007. doi:10.1182/blood-2006-06-031948 Evidence: High

     Verified 2026-09-26 · PMID 17185468 · DOI 10.1182/blood-2006-06-031948

     • What Matters: What moves blood-cancer death risk

981. wang2012diabetesmellitus

     C. Wang et al. Increased risk of hepatocellular carcinoma in patients with diabetes mellitus: a systematic review and meta-analysis of cohort studies. Int J Cancer, 130(7):1639-48, 2012. doi:10.1002/ijc.26165 Evidence: Moderate

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     • What Matters: Habits behind liver cancer death risk

982. wang2013obstructivesleep

     X. Wang et al. Obstructive sleep apnea and risk of cardiovascular disease and all-cause mortality: a meta-analysis of prospective cohort studies. Int J Cardiol, 169(3):207-14, 2013. doi:10.1016/j.ijcard.2013.08.088 Evidence: High

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     • Wiki: Insomnia
     • Wiki: Sleep duration and mortality
     • What Matters: Habits that swing heart-disease death risk

983. wang2013taichi

     N. Wang et al. Associations of Tai Chi, Walking, and Jogging With Mortality in Chinese Men. Am J Epidemiol, 178(5):791-796, 2013. doi:10.1093/aje/kwt050 Evidence: Low

     Verified 2026-09-26 · DOI 10.1093/aje/kwt050

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • Wiki: Fall prevention
     • Wiki: Yoga and tai chi
     • Wiki: Everyday movement (section)
     • What Matters: Movement: What Matters?

984. wang2014fruitvegetable

     X. Wang et al. Fruit and vegetable consumption and mortality from all causes, cardiovascular disease, and cancer: systematic review and dose-response meta-analysis of prospective cohort studies. BMJ, 349:g4490, 2014. doi:10.1136/bmj.g4490 Evidence: High

     Verified 2026-09-26 · PMID 25073782 · DOI 10.1136/bmj.g4490

     • Wiki: Fruit
     • What Matters: Habits that swing heart-disease death risk

985. wang2016meat

     X. Wang et al. Red and processed meat consumption and mortality: dose-response meta-analysis of prospective cohort studies. Public Health Nutr, 19(5):893-905, 2016. doi:10.1017/S1368980015002062 Evidence: High

     Verified 2026-10-01 · PMID 26143683 · DOI 10.1017/S1368980015002062

     • Wiki: Processed meat

986. wang2016toothloss

     Y. Wang et al. Association between tooth loss and risk of oesophageal cancer: a dose-response meta-analysis. Springerplus, 5(1):1020, 2016. doi:10.1186/s40064-016-2711-6 Evidence: Low

     Verified 2026-09-26 · PMID 27441139 · DOI 10.1186/s40064-016-2711-6

     • What Matters: Factors that swing esophageal cancer deaths

987. wang2018telomeremortality

     Q. Wang et al. Telomere Length and All-Cause Mortality: A Meta-analysis. Ageing Res Rev, 48:11-20, 2018. doi:10.1016/j.arr.2018.09.002 Evidence: Moderate

     Verified 2026-09-22 · PMID 30254001 · DOI 10.1016/j.arr.2018.09.002

     PR #555 audit: the original PMID (29129805) resolved to an unrelated rare-genetic-diseases review; corrected to 30254001. Also fixes a body-text mismatch that cited this as "Nature Aging, 2021" — the real paper is Ageing Research Reviews, 2018.

     • Wiki: Telomeres
     • Wiki: Longevity theories (section)

988. wang2020yogasleep

     W. L. Wang et al. The effect of yoga on sleep quality and insomnia in women with sleep problems: a systematic review and meta-analysis. BMC Psychiatry, 20(1):195, 2020. doi:10.1186/s12888-020-02566-4 Evidence: Moderate

     Verified 2026-10-08 · PMID 32357858 · DOI 10.1186/s12888-020-02566-4

     • Deep dive: Top 10 insomnia remedies, ranked by the evidence

989. wang2021bedtimepure

     C. Wang et al. Association of bedtime with mortality and major cardiovascular events: an analysis of 112,198 individuals from 21 countries in the PURE study. Sleep Med, 80:265-272, 2021. doi:10.1016/j.sleep.2021.01.057 Evidence: Moderate

     Verified 2026-09-30 · PMID 33610073 · DOI 10.1016/j.sleep.2021.01.057

     • What Matters: What sleep does to how long you live
     • Deep dive: How sleep affects how long you live
     • What Matters: The healthiest habits, ranked

990. wang2021fruitvegetable

     D. D. Wang et al. Fruit and Vegetable Intake and Mortality: Results From 2 Prospective Cohort Studies of US Men and Women and a Meta-Analysis of 26 Cohort Studies. Circulation, 143(17):1642-1654, 2021. doi:10.1161/CIRCULATIONAHA.120.048996 Evidence: High

     Verified 2026-09-28 · PMID 33641343 · DOI 10.1161/CIRCULATIONAHA.120.048996

     • Wiki: Fruit
     • Wiki: Vegetables
     • Wiki: Potatoes
     • Quiz: Diet
     • Quiz: Diet check

991. wang2024associationbetween2

     M. Wang et al. Association between self-reported napping and risk of cardiovascular disease and all-cause mortality: A meta-analysis of cohort studies. PLoS One, 19(10):e0311266, 2024. doi:10.1371/journal.pone.0311266 Evidence: Moderate

     Verified 2026-09-26 · DOI 10.1371/journal.pone.0311266

     • Wiki: Naps
     • Deep dive: Do naps make your brain younger, or are long ones a red flag?

992. wang2024restingheart

     J. Wang et al. Association between Resting Heart Rate and Machine Learning-Based Brain Age in Middle- and Older-Age. J Prev Alzheimers Dis, 11(4):1140-1147, 2024. doi:10.14283/jpad.2024.76 Evidence: Low

     Verified 2026-09-26 · PMID 39044526 · DOI 10.14283/jpad.2024.76

     • What Matters: What moves your cognitive age
     • Deep dive: How to lower your cognitive age: every habit with a number in years
     • What Matters: The healthiest habits, ranked

993. wang2025coffeedrinking

     X. Wang et al. Coffee drinking timing and mortality in US adults. Eur Heart J, 46(8):749-759, 2025. doi:10.1093/eurheartj/ehae871 Evidence: Low

     Verified 2026-09-26 · PMID 39776171 · DOI 10.1093/eurheartj/ehae871

     • What Matters: What sleep does to how long you live
     • Deep dive: How sleep affects how long you live
     • What Matters: The healthiest habits, ranked

994. ward2017phonepresence

     A. F. Ward et al. Brain Drain: The Mere Presence of One’s Own Smartphone Reduces Available Cognitive Capacity. J Assoc Consum Res, 2(2):140-154, 2017. doi:10.1086/691462 Evidence: Low

     Verified 2026-09-26 · DOI 10.1086/691462

     Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

     • What Matters: What stretches, or shreds, attention

995. wargocki2020classroomco2

     P. Wargocki et al. The relationships between classroom air quality and children’s performance in school. Build Environ, 173:106749, 2020. doi:10.1016/j.buildenv.2020.106749 Evidence: Low

     Verified 2026-09-26 · DOI 10.1016/j.buildenv.2020.106749

     • What Matters: What stretches, or shreds, attention

996. wastyk2021gutmicrobiota

     H. C. Wastyk et al. Gut-microbiota-targeted diets modulate human immune status. Cell, 184(16):4137-4153.e14, 2021. doi:10.1016/j.cell.2021.06.019 Evidence: Low

     Verified 2026-09-26 · PMID 34256014 · DOI 10.1016/j.cell.2021.06.019

     • Wiki: Colon health
     • Wiki: Inflammation and aging
     • Deep dive: The 9 things that matter most for your colon
     • Deep dive: The 9 things that matter most for taming inflammation

997. watts2022moudsuicide

     B. V. Watts et al. Association of Medication Treatment for Opioid Use Disorder With Suicide Mortality. Am J Psychiatry, 179(4):298-304, 2022. doi:10.1176/appi.ajp.2021.21070700 Evidence: Low

     Verified 2026-09-26 · PMID 35360916 · DOI 10.1176/appi.ajp.2021.21070700

     Metadata confirmed against the Europe PMC MEDLINE record for this PMID (NCBI E-utilities unavailable 2026-09-26).

     • What Matters: Factors linked to suicide deaths

998. webber2023activitypneumonia

     B. J. Webber, H. C. Yun, and G. P. Whitfield. Leisure-time physical activity and mortality from influenza and pneumonia: a cohort study of 577 909 US adults. Br J Sports Med, 57(19):1231-1237, 2023. doi:10.1136/bjsports-2022-106644 Evidence: Low

     Verified 2026-09-26 · PMID 37192831 · DOI 10.1136/bjsports-2022-106644

     • What Matters: Factors that swing flu and pneumonia deaths

999. welsh2019apoblipids

     C. Welsh et al. Comparison of Conventional Lipoprotein Tests and Apolipoproteins in the Prediction of Cardiovascular Disease. Circulation, 140(7):542-552, 2019. doi:10.1161/circulationaha.119.041149 Evidence: Low

     Verified 2026-09-27 · PMID 31216866 · DOI 10.1161/circulationaha.119.041149

     • Wiki: Cholesterol
     • Deep dive: The 9 things that matter most for your cholesterol

1000. wen201115minutes

      C. P. Wen et al. Minimum amount of physical activity for reduced mortality and extended life expectancy: a prospective cohort study. Lancet, 378(9798):1244-53, 2011. doi:10.1016/S0140-6736(11)60749-6 Evidence: Low

      Verified 2026-09-26 · PMID 21846575 · DOI 10.1016/S0140-6736(11)60749-6

      • Wiki: Exercise and longevity
      • Deep dive: The 8 things that matter most in exercise
      • Deep dive: Does having a pet actually help you live longer?

1001. western2024westernled

      Western University. Western-led study shows playing video games may improve cognitive performance. Western University News, 2024. Evidence: Not graded (news release)

      Verified 2026-09-27

      • What Matters: What moves your cognitive age
      • Deep dive: How to lower your cognitive age: every habit with a number in years
      • What Matters: The healthiest habits, ranked

1002. westgarth2019dogowners

      C. Westgarth et al. Dog owners are more likely to meet physical activity guidelines than people without a dog: An investigation of the association between dog ownership and physical activity levels in a UK community. Sci Rep, 9(1), 2019. doi:10.1038/s41598-019-41254-6 Evidence: Very low

      Verified 2026-09-26 · DOI 10.1038/s41598-019-41254-6

      • Wiki: Pet ownership
      • Deep dive: Does having a pet actually help you live longer?

1003. white2019spendingat

      M. P. White et al. Spending at least 120 minutes a week in nature is associated with good health and wellbeing. Sci Rep, 9(1), 2019. doi:10.1038/s41598-019-44097-3 Evidence: Very low

      Verified 2026-09-26 · DOI 10.1038/s41598-019-44097-3

      • Wiki: Green space
      • What Matters: Movement: What Matters?
      • Deep dive: Does living somewhere green actually help you live longer?

1004. whitehead2014oatbeta

      A. Whitehead et al. Cholesterol-lowering effects of oat β-glucan: a meta-analysis of randomized controlled trials. Am J Clin Nutr, 100(6):1413-21, 2014. doi:10.3945/ajcn.114.086108 Evidence: High

      Verified 2026-09-26 · PMID 25411276 · DOI 10.3945/ajcn.114.086108

      • Wiki: Cholesterol
      • Deep dive: The 9 things that matter most for your cholesterol

1005. whiteman2001sunburnmelanoma

      D. C. Whiteman, C. A. Whiteman, and A. C. Green. Childhood sun exposure as a risk factor for melanoma: a systematic review of epidemiologic studies. Cancer Causes Control, 12(1):69-82, 2001. doi:10.1023/a:1008980919928 Evidence: Low

      Verified 2026-09-27 · PMID 11227927 · DOI 10.1023/a:1008980919928

      • Wiki: Skin aging
      • Deep dive: What your skin is actually telling you about how long you live
      • Quiz: Environment

1006. who2020uvradiation

      World Health Organization. Ultraviolet radiation. WHO fact sheet, 2020. Evidence: Not graded (reference page)

      Verified 2026-09-27

      • Wiki: Skin aging
      • Wiki: Skin and hair (section)
      • Deep dive: What your skin is actually telling you about how long you live
      • Quiz: Skin health
      • What Matters: What Affects Lifespan the Most
      • What Matters: The healthiest habits, ranked

1007. who2023aspartamehazard

      World Health Organization, IARC, FAO/WHO JECFA. Aspartame hazard and risk assessment results released. WHO news release, 2023. Evidence: Not graded (news release)

      Verified 2026-10-05

      Joint IARC (hazard, Group 2B) and JECFA (risk, ADI 0-40 mg/kg) statement; the IARC Lancet Oncology summary is doi:10.1016/S1470-2045(23)00341-8.

      • Deep dive: Diet soda vs regular soda vs water: what the evidence shows

1008. who2023globalreport

      WHO. Global report on hypertension: the race against a silent killer. WHO, 2023. Evidence: Not graded (statistics)

      Verified 2026-09-27

      • Deep dive: Is your blood pressure quietly aging you? The 9 things that matter most
      • Quiz: Blood pressure check

1009. who2023nssguideline

      World Health Organization. Use of non-sugar sweeteners: WHO guideline. WHO, 2023. Evidence: Not graded (guideline)

      Verified 2026-10-05

      • Deep dive: Diet soda vs regular soda vs water: what the evidence shows

1010. wieland2022yoga

      L. S. Wieland et al. Yoga for chronic non-specific low back pain. Cochrane Database Syst Rev, 11(11):CD010671, 2022. doi:10.1002/14651858.CD010671.pub3 Evidence: Moderate

      Verified 2026-09-28 · PMID 36398843 · DOI 10.1002/14651858.CD010671.pub3

      • Wiki: Yoga and tai chi

1011. wiese2018opioidpneumococcal

      A. D. Wiese et al. Opioid Analgesic Use and Risk for Invasive Pneumococcal Diseases: A Nested Case-Control Study. Ann Intern Med, 168(6):396-404, 2018. doi:10.7326/M17-1907 Evidence: Low

      Verified 2026-09-26 · PMID 29435555 · DOI 10.7326/M17-1907

      Nested case-control in Tennessee Medicaid; prescription opioid fills only, illicit use not measured.

      • What Matters: Factors that swing flu and pneumonia deaths

1012. wikoff2017caffeinesafety

      D. Wikoff et al. Systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. Food Chem Toxicol, 109(Pt 1):585-648, 2017. doi:10.1016/j.fct.2017.04.002 Evidence: Moderate

      Verified 2026-09-29 · PMID 28438661 · DOI 10.1016/j.fct.2017.04.002

      • Wiki: Coffee, tea and energy drinks

1013. wild2018dissociableeffects

      C. J. Wild et al. Dissociable effects of self-reported daily sleep duration on high-level cognitive abilities. Sleep, 41(12), 2018. doi:10.1093/sleep/zsy182 Evidence: Very low

      Verified 2026-09-26 · DOI 10.1093/sleep/zsy182

      Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

      • Wiki: Cognitive aging
      • Wiki: Brain health (section)
      • What Matters: What moves your cognitive age
      • Deep dive: How to lower your cognitive age: every habit with a number in years
      • What Matters: The healthiest habits, ranked

1014. wilker2023pm25

      E. H. Wilker, M. Osman, and M. G. Weisskopf. Ambient air pollution and clinical dementia: systematic review and meta-analysis. BMJ, 381:e071620, 2023. doi:10.1136/bmj-2022-071620 Evidence: Moderate

      Verified 2026-09-26 · PMID 37019461 · DOI 10.1136/bmj-2022-071620

      • Wiki: Dementia risk factors
      • Deep dive: How to escape dementia: all 14 risk factors, ranked

1015. wilson2021cognitiveactivity

      R. S. Wilson et al. Cognitive Activity and Onset Age of Incident Alzheimer Disease Dementia. Neurology, 97(9):e922-e929, 2021. doi:10.1212/WNL.0000000000012388 Evidence: Low

      Verified 2026-09-26 · PMID 34261788 · DOI 10.1212/WNL.0000000000012388

      • What Matters: What moves your cognitive age
      • Deep dive: How to lower your cognitive age: every habit with a number in years
      • What Matters: The healthiest habits, ranked

1016. win2015familyhistory

      A. K. Win, J. C. Reece, and S. Ryan. Family history and risk of endometrial cancer: a systematic review and meta-analysis. Obstet Gynecol, 125(1):89-98, 2015. doi:10.1097/AOG.0000000000000563 Evidence: High

      Verified 2026-09-26 · PMID 25560109 · DOI 10.1097/AOG.0000000000000563

      • What Matters: Habits that change uterine cancer death risk

1017. windred2024personalday

      D. P. Windred et al. Brighter nights and darker days predict higher mortality risk: A prospective analysis of personal light exposure in >88,000 individuals. Proc Natl Acad Sci U S A, 121(43):e2405924121, 2024. doi:10.1073/pnas.2405924121 Evidence: Low

      Verified 2026-09-26 · PMID 39405349 · DOI 10.1073/pnas.2405924121

      • What Matters: What sleep does to how long you live
      • Deep dive: How sleep affects how long you live
      • What Matters: The healthiest habits, ranked

1018. windred2024regularityremainder

      D. P. Windred et al. Sleep regularity is a stronger predictor of mortality risk than sleep duration: A prospective cohort study. Sleep, 47(1), 2024. doi:10.1093/sleep/zsad253 Evidence: Low

      Verified 2026-09-26 · PMID 37738616 · DOI 10.1093/sleep/zsad253

      • Wiki: Sleep duration and mortality
      • Wiki: Sleep quality
      • What Matters: What sleep does to how long you live
      • What Matters: What actually moves sleep quality
      • Deep dive: The 8 things that matter most for your sleep
      • Deep dive: The 8 things that matter most for staying calm
      • Deep dive: How sleep affects how long you live
      • Deep dive: What matters most for high-quality sleep
      • Deep dive: Bryan Johnson's Ten Sleep Power Laws: what each one asks and how strong the evidence is
      • Quiz: Bryan Johnson's Ten Sleep Power Laws
      • Quiz: Sleep
      • Quiz: Sleep check
      • What Matters: The healthiest habits, ranked

1019. wiradhany2017cognitivecontrol

      W. Wiradhany and M. R. Nieuwenstein. Cognitive control in media multitaskers: Two replication studies and a meta-Analysis. Atten Percept Psychophys, 79(8):2620-2641, 2017. doi:10.3758/s13414-017-1408-4 Evidence: Low

      Verified 2026-09-28 · PMID 28840547 · DOI 10.3758/s13414-017-1408-4

      • What Matters: What stretches, or shreds, attention

1020. wiradhany2021mediamultitasking

      D. A. Parry and D. B. Le Roux. “Cognitive control in media multitaskers” ten years on: A meta-analysis. Cyberpsychology (Brno), 15(2), 2021. doi:10.5817/CP2021-2-7 Evidence: Low

      Verified 2026-09-26 · DOI 10.5817/CP2021-2-7

      Automated link-check got HTTP ERR:The read operation timed out (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

      • What Matters: What stretches, or shreds, attention

1021. witkowski2023erythritol

      M. Witkowski et al. The artificial sweetener erythritol and cardiovascular event risk. Nat Med, 29(3):710-718, 2023. doi:10.1038/s41591-023-02223-9 Evidence: Very low

      Verified 2026-10-05 · PMID 36849732 · DOI 10.1038/s41591-023-02223-9

      • Deep dive: Diet soda vs regular soda vs water: what the evidence shows

1022. wittbrodt2018dehydrationattention

      M. T. WITTBRODT and M. MILLARD-STAFFORD. Dehydration Impairs Cognitive Performance: A Meta-analysis. Med Sci Sports Exerc, 50(11):2360-2368, 2018. doi:10.1249/mss.0000000000001682 Evidence: Low

      Verified 2026-09-26 · DOI 10.1249/mss.0000000000001682

      • What Matters: What stretches, or shreds, attention

1023. wolf1991atrialfibrillation

      P. A. Wolf, R. D. Abbott, and W. B. Kannel. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke, 22(8):983-8, 1991. doi:10.1161/01.str.22.8.983 Evidence: Low

      Verified 2026-09-26 · PMID 1866765 · DOI 10.1161/01.str.22.8.983

      • What Matters: What raises — or cuts — stroke death risk

1024. wolin2009physicalactivity

      K. Y. Wolin et al. Physical activity and colon cancer prevention: a meta-analysis. Br J Cancer, 100(4):611-6, 2009. doi:10.1038/sj.bjc.6604917 Evidence: High

      Verified 2026-09-26 · PMID 19209175 · DOI 10.1038/sj.bjc.6604917

      • Wiki: Colon health
      • Deep dive: The 9 things that matter most for your colon

1025. wolters2017parentaldementia

      F. J. Wolters et al. Parental family history of dementia in relation to subclinical brain disease and dementia risk. Neurology, 88(17):1642-1649, 2017. doi:10.1212/WNL.0000000000003871 Evidence: Low

      Verified 2026-10-08 · PMID 28356461 · DOI 10.1212/WNL.0000000000003871

      • Deep dive: What you inherit from your family, and what you don’t
      • What Matters: What Affects Lifespan the Most

1026. wood2018alcohol

      A. M. Wood et al. Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies. Lancet, 391(10129):1513-1523, 2018. doi:10.1016/S0140-6736(18)30134-X Evidence: High

      Verified 2026-09-26 · PMID 29676281 · DOI 10.1016/S0140-6736(18)30134-X

      • Wiki: Alcohol
      • Wiki: Alcohol and tobacco (section)
      • Deep dive: The 7 things to know about alcohol
      • Quiz: Alcohol
      • What Matters: Habits that swing heart-disease death risk
      • What Matters: What Affects Lifespan the Most
      • What Matters: The healthiest habits, ranked

1027. worldnadeafnesshearing

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      Verified 2026-09-27

      Continuously-updated fact sheet, no single publication year stated.

      • Wiki: Hearing and vision loss
      • Wiki: Brain health (section)
      • Deep dive: Are your ears and eyes quietly aging your brain?

1028. wright2013daylightclock

      K. P. Wright Jr. et al. Entrainment of the human circadian clock to the natural light-dark cycle. Curr Biol, 23(16):1554-8, 2013. doi:10.1016/j.cub.2013.06.039 Evidence: Very low

      Verified 2026-09-26 · PMID 23910656 · DOI 10.1016/j.cub.2013.06.039

      • Wiki: Sleep physiology
      • Wiki: Insomnia
      • Wiki: Sleep quality
      • What Matters: What actually moves sleep quality
      • Deep dive: The 8 things that matter most for your sleep
      • Deep dive: What matters most for high-quality sleep
      • Deep dive: Bryan Johnson's Ten Sleep Power Laws: what each one asks and how strong the evidence is
      • Deep dive: Top 10 insomnia remedies, ranked by the evidence

1029. wu2023qualityplant

      H. Wu et al. Quality of plant-based diet and the risk of dementia and depression among middle-aged and older population. Age Ageing, 52(5), 2023. doi:10.1093/ageing/afad070 Evidence: Low

      Verified 2026-09-26 · PMID 37247402 · DOI 10.1093/ageing/afad070

      • Wiki: Dementia risk factors
      • Deep dive: Plants and your brain: what the vegetarian, Mediterranean and MIND studies really show about dementia

1030. xia2017cigarettesmoking

      J. Xia et al. Cigarette smoking and chronic kidney disease in the general population: a systematic review and meta-analysis of prospective cohort studies. Nephrol Dial Transplant, 32(3):475-487, 2017. doi:10.1093/ndt/gfw452 Evidence: Moderate

      Verified 2026-09-26 · PMID 28339863 · DOI 10.1093/ndt/gfw452

      • What Matters: Factors that swing kidney disease deaths

1031. xie2013metabolite

      L. Xie et al. Sleep drives metabolite clearance from the adult brain. Science, 342(6156):373-7, 2013. doi:10.1126/science.1241224 Evidence: Very low

      Verified 2026-09-22 · PMID 24136970 · DOI 10.1126/science.1241224

      • Wiki: Sleep physiology

1032. xie2021exercise22

      Y. Xie et al. Effects of Exercise on Sleep Quality and Insomnia in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Front Psychiatry, 12:664499, 2021. doi:10.3389/fpsyt.2021.664499 Evidence: Moderate

      Verified 2026-09-26 · PMID 34163383 · DOI 10.3389/fpsyt.2021.664499

      • Wiki: Sleep quality
      • What Matters: What actually moves sleep quality
      • Deep dive: What matters most for high-quality sleep
      • Deep dive: Top 10 insomnia remedies, ranked by the evidence
      • What Matters: The healthiest habits, ranked

1033. xu2022sarcopeniamortality

      J. Xu et al. Sarcopenia Is Associated with Mortality in Adults: A Systematic Review and Meta-Analysis. Gerontology, 68(4):361-376, 2022. doi:10.1159/000517099 Evidence: Moderate

      Verified 2026-09-28 · PMID 34315158 · DOI 10.1159/000517099

      • Wiki: Sarcopenia
      • Wiki: Strength and muscle (section)

1034. xue2014redprocessed

      X. J. Xue et al. Red and processed meat consumption and the risk of lung cancer: a dose-response meta-analysis of 33 published studies. Int J Clin Exp Med, 7(6):1542-53, 2014. Evidence: Moderate

      Verified 2026-09-26 · PMID 25035778

      • What Matters: Smoking and the rest: lung cancer death risk

1035. yaggi2005obstructivesleep

      H. K. Yaggi et al. Obstructive sleep apnea as a risk factor for stroke and death. N Engl J Med, 353(19):2034-41, 2005. doi:10.1056/NEJMoa043104 Evidence: Low

      Verified 2026-09-26 · PMID 16282178 · DOI 10.1056/NEJMoa043104

      • What Matters: What raises — or cuts — stroke death risk

1036. yakobi2021mindfulnessattention

      D. Sumantry and K. E. Stewart. Meditation, Mindfulness, and Attention: a Meta-analysis. Mindfulness, 12(6):1332-1349, 2021. doi:10.1007/s12671-021-01593-w Evidence: Low

      Verified 2026-09-26 · DOI 10.1007/s12671-021-01593-w

      • What Matters: What stretches, or shreds, attention

1037. yamada2013malepattern

      T. Yamada et al. Male pattern baldness and its association with coronary heart disease: a meta-analysis. BMJ Open, 3(4):e002537, 2013. doi:10.1136/bmjopen-2012-002537 Evidence: Moderate

      Verified 2026-09-27 · PMID 23554099 · DOI 10.1136/bmjopen-2012-002537

      • Wiki: Hair loss
      • Wiki: Skin and hair (section)
      • Deep dive: The 9 things balding is actually telling you about your health

1038. yamada2015daytimenapping

      T. Yamada et al. Daytime Napping and the Risk of Cardiovascular Disease and All-Cause Mortality: A Prospective Study and Dose-Response Meta-Analysis. Sleep, 38(12):1945-53, 2015. doi:10.5665/sleep.5246 Evidence: High

      Verified 2026-09-26 · PMID 26158892 · DOI 10.5665/sleep.5246

      • Wiki: Sleep duration and mortality
      • Wiki: Sleep quality
      • Wiki: Naps
      • What Matters: What sleep does to how long you live
      • What Matters: What actually moves sleep quality
      • Deep dive: The 8 things that matter most for your sleep
      • Deep dive: How sleep affects how long you live
      • Deep dive: What matters most for high-quality sleep
      • Deep dive: Do naps make your brain younger, or are long ones a red flag?
      • What Matters: The healthiest habits, ranked

1039. yamadera2007glycine

      W. YAMADERA et al. Glycine ingestion improves subjective sleep quality in human volunteers, correlating with polysomnographic changes. Sleep Biol Rhythms, 5(2):126-131, 2007. doi:10.1111/j.1479-8425.2007.00262.x Evidence: Low

      Verified 2026-09-22 · DOI 10.1111/j.1479-8425.2007.00262.x

      PR #555 audit: direct fetch returns 403 (bot-blocked, not dead); the DOI and paper were confirmed by hand.

      • Wiki: Glycine (supplement)

1040. yang2014vegetablefruit

      Y. Yang et al. Increased intake of vegetables, but not fruit, reduces risk for hepatocellular carcinoma: a meta-analysis. Gastroenterology, 147(5):1031-42, 2014. doi:10.1053/j.gastro.2014.08.005 Evidence: High

      Verified 2026-09-26 · PMID 25127680 · DOI 10.1053/j.gastro.2014.08.005

      • What Matters: Habits behind liver cancer death risk

1041. yang2022foodgroupsINCOMPLETE METADATA

      J. Yang et al. Joint Associations of Food Groups with All-Cause and Cause-Specific Mortality in the Mr. OS and Ms. OS Study: A Prospective Cohort. Nutrients, 14(19), 2022. doi:10.3390/nu14193915 Evidence: Low

      Verified 2026-10-01 · PMID 36235568 · DOI 10.3390/nu14193915

      PubMed lists no pages for this paper yet (checked 2026-10-01).

      • Wiki: Legumes

1042. yang2023chili

      L. Yang et al. Chili pepper intake and all-cause and disease-specific mortality. Int J Vitam Nutr Res, 93(4):378-384, 2023. doi:10.1024/0300-9831/a000746 Evidence: Moderate

      Verified 2026-10-01 · PMID 35038885 · DOI 10.1024/0300-9831/a000746

      • Wiki: Chili peppers

1043. yeo2023hearingaids

      B. S. Y. Yeo et al. Association of Hearing Aids and Cochlear Implants With Cognitive Decline and Dementia: A Systematic Review and Meta-analysis. JAMA Neurol, 80(2):134-141, 2023. doi:10.1001/jamaneurol.2022.4427 Evidence: High

      Verified 2026-09-27 · PMID 36469314 · DOI 10.1001/jamaneurol.2022.4427

      • Wiki: Hearing and vision loss
      • What Matters: What raises dementia risk most
      • Deep dive: How to escape dementia: all 14 risk factors, ranked
      • What Matters: Factors behind Alzheimer’s death risk
      • What Matters: The healthiest habits, ranked

1044. yi2026sugarsweetened

      K. Yi et al. Higher consumption of sugar-sweetened beverages is associated with an increased risk of endometrial cancer: a prospective cohort study of 92,777 women from the UK Biobank. Front Public Health, 13:1692974, 2026. doi:10.3389/fpubh.2025.1692974 Evidence: Low

      Verified 2026-09-26 · PMID 41573798 · DOI 10.3389/fpubh.2025.1692974

      • What Matters: Habits that change uterine cancer death risk

1045. young2008wisconsinsleep

      T. Young et al. Sleep disordered breathing and mortality: eighteen-year follow-up of the Wisconsin sleep cohort. Sleep, 31(8):1071-8, 2008. Evidence: Low

      Verified 2026-09-26 · PMID 18714778

      • Wiki: Insomnia
      • Wiki: Sleep duration and mortality
      • Wiki: Sleep quality
      • What Matters: What sleep does to how long you live
      • Deep dive: The 8 things that matter most for your sleep
      • Deep dive: How sleep affects how long you live
      • Deep dive: What matters most for high-quality sleep
      • Deep dive: Top 10 insomnia remedies, ranked by the evidence
      • Quiz: Sleep
      • Quiz: Sleep check
      • What Matters: The healthiest habits, ranked

1046. yu2000familialrisk

      M. W. Yu et al. Familial risk of hepatocellular carcinoma among chronic hepatitis B carriers and their relatives. J Natl Cancer Inst, 92(14):1159-64, 2000. doi:10.1093/jnci/92.14.1159 Evidence: Low

      Verified 2026-09-26 · PMID 10904089 · DOI 10.1093/jnci/92.14.1159

      • What Matters: Habits behind liver cancer death risk

1047. yu2016coffeeconsumption

      C. Yu et al. An updated dose-response meta-analysis of coffee consumption and liver cancer risk. Sci Rep, 6:37488, 2016. doi:10.1038/srep37488 Evidence: High

      Verified 2026-09-26 · PMID 27910873 · DOI 10.1038/srep37488

      • What Matters: Habits behind liver cancer death risk

1048. yu2022familyhistory

      E. Y. Yu et al. Family History and Risk of Bladder Cancer: An Analysis Accounting for First- and Second-degree Relatives. Cancer Prev Res (Phila), 15(5):319-326, 2022. doi:10.1158/1940-6207.CAPR-21-0490 Evidence: Moderate

      Verified 2026-09-26 · PMID 35027464 · DOI 10.1158/1940-6207.CAPR-21-0490

      • What Matters: What changes bladder cancer death risk

1049. yusuf2004interheart9

      S. Yusuf et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet, 364(9438):937-52, 2004. doi:10.1016/S0140-6736(04)17018-9 Evidence: Moderate

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      • Wiki: Cardiovascular disease
      • Wiki: Family history and genetics
      • Wiki: Heart and metabolic health (section)
      • Deep dive: What you inherit from your family, and what you don’t
      • What Matters: Habits that swing heart-disease death risk

1050. zaccardi2017saunabathing

      F. Zaccardi et al. Sauna Bathing and Incident Hypertension: A Prospective Cohort Study. Am J Hypertens, 30(11):1120-1125, 2017. doi:10.1093/ajh/hpx102 Evidence: Low

      Verified 2026-09-27 · PMID 28633297 · DOI 10.1093/ajh/hpx102

      • Wiki: Heat exposure
      • Deep dive: Does the sauna actually make you live longer?

1051. zainal2023mindfulness111

      N. H. Zainal and M. G. Newman. Mindfulness enhances cognitive functioning: a meta-analysis of 111 randomized controlled trials. Health Psychol Rev, 18(2):369-395, 2023. doi:10.1080/17437199.2023.2248222 Evidence: Moderate

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      Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

      • What Matters: What stretches, or shreds, attention

1052. zargarzadeh2023legumes

      N. Zargarzadeh et al. Legume Consumption and Risk of All-Cause and Cause-Specific Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Studies. Adv Nutr, 14(1):64-76, 2023. doi:10.1016/j.advnut.2022.10.009 Evidence: Moderate

      Verified 2026-10-01 · PMID 36811595 · DOI 10.1016/j.advnut.2022.10.009

      • Wiki: Legumes
      • What Matters: Foods ranked for longevity

1053. zauber2012polypectomy

      A. G. Zauber et al. Colonoscopic polypectomy and long-term prevention of colorectal-cancer deaths. N Engl J Med, 366(8):687-96, 2012. doi:10.1056/NEJMoa1100370 Evidence: Low

      Verified 2026-09-26 · PMID 22356322 · DOI 10.1056/NEJMoa1100370

      Cited from both the gut/colon-health and preventive-care markers; one registry entry, two citers.

      • Wiki: Dietary fiber
      • Wiki: Colon health
      • Wiki: Digestive and oral health (section)
      • Deep dive: The 9 things that matter most for your colon
      • Deep dive: Why doctors will not shut up about fiber
      • Quiz: Gut & colon health
      • Quiz: Preventive care
      • What Matters: What Affects Lifespan the Most
      • What Matters: The healthiest habits, ranked

1054. zeraatkar2019meat

      D. Zeraatkar et al. Red and Processed Meat Consumption and Risk for All-Cause Mortality and Cardiometabolic Outcomes: A Systematic Review and Meta-analysis of Cohort Studies. Ann Intern Med, 171(10):703-710, 2019. doi:10.7326/M19-0655 Evidence: Moderate

      Verified 2026-10-01 · PMID 31569213 · DOI 10.7326/M19-0655

      • Wiki: Red meat

1055. zhang2006smokingremainder

      L. Zhang et al. Cigarette smoking and nocturnal sleep architecture. Am J Epidemiol, 164(6):529-37, 2006. doi:10.1093/aje/kwj231 Evidence: Very low

      Verified 2026-09-26 · PMID 16829553 · DOI 10.1093/aje/kwj231

      • What Matters: What actually moves sleep quality
      • Deep dive: What matters most for high-quality sleep

1056. zhang2016fishpufa

      Y. Zhang et al. Intakes of fish and polyunsaturated fatty acids and mild-to-severe cognitive impairment risks: a dose-response meta-analysis of 21 cohort studies. Am J Clin Nutr, 103(2):330-40, 2016. doi:10.3945/ajcn.115.124081 Evidence: Moderate

      Verified 2026-09-26 · PMID 26718417 · DOI 10.3945/ajcn.115.124081

      • Wiki: Dementia risk factors
      • Deep dive: Plants and your brain: what the vegetarian, Mediterranean and MIND studies really show about dementia

1057. zhang2016restingheart

      D. Zhang, X. Shen, and X. Qi. Resting heart rate and all-cause and cardiovascular mortality in the general population: a meta-analysis. CMAJ, 188(3):E53-E63, 2016. doi:10.1503/cmaj.150535 Evidence: High

      Verified 2026-09-27 · PMID 26598376 · DOI 10.1503/cmaj.150535

      • Wiki: Cardiovascular disease
      • Deep dive: The 10 things that matter most for your heart
      • Deep dive: Body Check: five at-home tests linked to how long you live
      • What Matters: Habits that swing heart-disease death risk

1058. zhang2017diabetesmellitus

      D. Zhang et al. Diabetes mellitus and risk of ovarian cancer. A systematic review and meta-analysis of 15 cohort studies. Diabetes Res Clin Pract, 130:43-52, 2017. doi:10.1016/j.diabres.2017.04.005 Evidence: Moderate

      Verified 2026-09-26 · PMID 28554142 · DOI 10.1016/j.diabres.2017.04.005

      • What Matters: What raises ovarian cancer death risk

1059. zhang2021meatconsumption

      H. Zhang et al. Meat consumption and risk of incident dementia: cohort study of 493,888 UK Biobank participants. Am J Clin Nutr, 114(1):175-184, 2021. doi:10.1093/ajcn/nqab028 Evidence: Low

      Verified 2026-09-26 · PMID 33748832 · DOI 10.1093/ajcn/nqab028

      • Wiki: Dementia risk factors
      • Deep dive: Plants and your brain: what the vegetarian, Mediterranean and MIND studies really show about dementia

1060. zhang2021ssbasb

      Y. B. Zhang et al. Association of Consumption of Sugar-Sweetened Beverages or Artificially Sweetened Beverages with Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies. Adv Nutr, 12(2):374-383, 2021. doi:10.1093/advances/nmaa110 Evidence: High

      Verified 2026-10-01 · PMID 33786594 · DOI 10.1093/advances/nmaa110

      • Wiki: Diet drinks
      • Wiki: Sugary drinks
      • What Matters: Foods ranked for longevity
      • Deep dive: Diet soda vs regular soda vs water: what the evidence shows

1061. zhang2023cheese

      M. Zhang et al. Cheese consumption and multiple health outcomes: an umbrella review and updated meta-analysis of prospective studies. Adv Nutr, 14(5):1170-1186, 2023. doi:10.1016/j.advnut.2023.06.007 Evidence: High

      Verified 2026-10-01 · PMID 37328108 · DOI 10.1016/j.advnut.2023.06.007

      • Wiki: Cheese
      • What Matters: Foods ranked for longevity

1062. zhang2024berries

      L. Zhang et al. Consumption of Berries and Flavonoids in Relation to Mortality in NHANES, 1999-2014. J Nutr, 154(2):734-743, 2024. doi:10.1016/j.tjnut.2024.01.002 Evidence: Low

      Verified 2026-10-01 · PMID 38184200 · DOI 10.1016/j.tjnut.2024.01.002

      • Wiki: Berries
      • What Matters: Foods ranked for longevity

1063. zhang2025butteroils

      Y. Zhang et al. Butter and Plant-Based Oils Intake and Mortality. JAMA Intern Med, 185(5):549-560, 2025. doi:10.1001/jamainternmed.2025.0205 Evidence: Moderate

      Verified 2026-10-01 · PMID 40048719 · DOI 10.1001/jamainternmed.2025.0205

      • Wiki: Olive oil
      • Wiki: Butter

1064. zhao2016fish

      L. G. Zhao et al. Fish consumption and all-cause mortality: a meta-analysis of cohort studies. Eur J Clin Nutr, 70(2):155-61, 2016. doi:10.1038/ejcn.2015.72 Evidence: High

      Verified 2026-10-01 · PMID 25969396 · DOI 10.1038/ejcn.2015.72

      • Wiki: Fish

1065. zhao2016isalcohol

      J. Zhao et al. Is alcohol consumption a risk factor for prostate cancer? A systematic review and meta-analysis. BMC Cancer, 16(1):845, 2016. doi:10.1186/s12885-016-2891-z Evidence: High

      Verified 2026-09-26 · PMID 27842506 · DOI 10.1186/s12885-016-2891-z

      • What Matters: Levers on prostate cancer death risk

1066. zhao2017associationbody

      L. Zhao et al. Association of body mass index with bladder cancer risk: a dose-response meta-analysis of prospective cohort studies. Oncotarget, 8(20):33990-34000, 2017. doi:10.18632/oncotarget.16722 Evidence: High

      Verified 2026-09-26 · PMID 28389625 · DOI 10.18632/oncotarget.16722

      • What Matters: What changes bladder cancer death risk

1067. zhao2023biascorrected

      J. Zhao et al. Association Between Daily Alcohol Intake and Risk of All-Cause Mortality: A Systematic Review and Meta-analyses. JAMA Netw Open, 6(3):e236185, 2023. doi:10.1001/jamanetworkopen.2023.6185 Evidence: High

      Verified 2026-09-27 · PMID 37000449 · DOI 10.1001/jamanetworkopen.2023.6185

      • Wiki: Alcohol
      • Wiki: Alcohol and tobacco (section)
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      • What Matters: Foods ranked for longevity
      • Deep dive: The 7 things to know about alcohol

1068. zhao2023specificbotanical

      L. Zhao et al. Specific botanical groups of fruit and vegetable consumption and liver cancer and chronic liver disease mortality: a prospective cohort study. Am J Clin Nutr, 117(2):278-285, 2023. doi:10.1016/j.ajcnut.2022.12.004 Evidence: Low

      Verified 2026-09-26 · PMID 36811575 · DOI 10.1016/j.ajcnut.2022.12.004

      • What Matters: Factors that swing liver disease deaths

1069. zhao2023sugarsweetened

      L. Zhao et al. Sugar-Sweetened and Artificially Sweetened Beverages and Risk of Liver Cancer and Chronic Liver Disease Mortality. JAMA, 330(6):537-546, 2023. doi:10.1001/jama.2023.12618 Evidence: Low

      Verified 2026-09-26 · PMID 37552302 · DOI 10.1001/jama.2023.12618

      • What Matters: Factors that swing liver disease deaths

1070. zheng2020yogurtconsumption

      X. Zheng et al. Yogurt consumption and risk of conventional and serrated precursors of colorectal cancer. Gut, 69(5):970-972, 2020. doi:10.1136/gutjnl-2019-318374 Evidence: Low

      Verified 2026-09-27 · PMID 31209182 · DOI 10.1136/gutjnl-2019-318374

      • Wiki: Colon health
      • Deep dive: The 9 things that matter most for your colon

1071. zhong2014nonoccupationalphysical

      S. Zhong et al. Nonoccupational physical activity and risk of ovarian cancer: a meta-analysis. Tumour Biol, 35(11):11065-73, 2014. doi:10.1007/s13277-014-2385-z Evidence: Low

      Verified 2026-09-26 · PMID 25095977 · DOI 10.1007/s13277-014-2385-z

      • What Matters: What raises ovarian cancer death risk

1072. zhong2015smokingdementia

      G. Zhong et al. Smoking Is Associated with an Increased Risk of Dementia: A Meta-Analysis of Prospective Cohort Studies with Investigation of Potential Effect Modifiers. PLoS One, 10(3):e0118333, 2015. doi:10.1371/journal.pone.0118333 Evidence: High

      Verified 2026-09-26 · DOI 10.1371/journal.pone.0118333

      • Wiki: Smoking
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      • What Matters: What raises dementia risk most
      • Deep dive: How to escape dementia: all 14 risk factors, ranked
      • What Matters: Factors behind Alzheimer’s death risk
      • What Matters: The healthiest habits, ranked

1073. zhong2020redprocessed

      V. W. Zhong et al. Associations of Processed Meat, Unprocessed Red Meat, Poultry, or Fish Intake With Incident Cardiovascular Disease and All-Cause Mortality. JAMA Intern Med, 180(4):503-512, 2020. doi:10.1001/jamainternmed.2019.6969 Evidence: High

      Verified 2026-09-26 · PMID 32011623 · DOI 10.1001/jamainternmed.2019.6969

      • Wiki: Dietary patterns
      • Deep dive: Vegan, vegetarian, omnivore, carnivore: what the labels actually buy you
      • Quiz: Diet

1074. zhong2021chocolate

      G. C. Zhong et al. Chocolate consumption and all-cause and cause-specific mortality in a US population: a post hoc analysis of the PLCO cancer screening trial. Aging (Albany NY), 13(14):18564-18585, 2021. doi:10.18632/aging.203302 Evidence: Low

      Verified 2026-10-01 · PMID 34329196 · DOI 10.18632/aging.203302

      • Wiki: Chocolate

1075. zhou2012reexaminationtotal

      J. Zhou et al. Reexamination of Total Fluid Intake and Bladder Cancer in the Health Professionals Follow-Up Study Cohort. Am J Epidemiol, 175(7):696-705, 2012. doi:10.1093/aje/kwr359 Evidence: Low

      Verified 2026-09-26 · DOI 10.1093/aje/kwr359

      Automated link-check got HTTP 403 (bot-block/rate-limit typical of this domain, not necessarily broken); URL carried over from pre-existing curated content, not independently re-verified against the paper in this pass.

      • What Matters: What changes bladder cancer death risk

1076. zhu2013redprocessed

      H. Zhu et al. Red and processed meat intake is associated with higher gastric cancer risk: a meta-analysis of epidemiological observational studies. PLoS One, 8(8):e70955, 2013. doi:10.1371/journal.pone.0070955 Evidence: Moderate

      Verified 2026-09-26 · PMID 23967140 · DOI 10.1371/journal.pone.0070955

      • Wiki: Helicobacter pylori
      • Deep dive: H. pylori and stomach cancer: what the evidence shows
      • What Matters: What raises stomach cancer death risk

1077. zhu2013riskbladder

      Z. Zhu et al. Risk of bladder cancer in patients with diabetes mellitus: an updated meta-analysis of 36 observational studies. BMC Cancer, 13:310, 2013. doi:10.1186/1471-2407-13-310 Evidence: Moderate

      Verified 2026-09-26 · PMID 23803148 · DOI 10.1186/1471-2407-13-310

      • What Matters: What changes bladder cancer death risk

1078. zick2011chamomile

      S. M. Zick et al. Preliminary examination of the efficacy and safety of a standardized chamomile extract for chronic primary insomnia: a randomized placebo-controlled pilot study. BMC Complement Altern Med, 11:78, 2011. doi:10.1186/1472-6882-11-78 Evidence: Low

      Verified 2026-09-22 · PMID 21939549 · DOI 10.1186/1472-6882-11-78

      PR #555 audit: the original PMID (21294900) resolved to an unrelated GWAS serum-uric-acid study; corrected to 21939549. Not all outcomes reached statistical significance.

      • Wiki: Apigenin (supplement)

1079. zuin2021atrialfibrillation

      M. Zuin et al. Risk of dementia in patients with atrial fibrillation: Short versus long follow-up. A systematic review and meta-analysis. Int J Geriatr Psychiatry, 36(10):1488-1500, 2021. doi:10.1002/gps.5582 Evidence: Moderate

      Verified 2026-09-26 · PMID 34043846 · DOI 10.1002/gps.5582

      • What Matters: What raises dementia risk most
      • Deep dive: How to escape dementia: all 14 risk factors, ranked
      • What Matters: Factors behind Alzheimer’s death risk

1080. zunhammer2014sleepquality

      M. Zunhammer, P. Eichhammer, and V. Busch. Sleep Quality during Exam Stress: The Role of Alcohol, Caffeine and Nicotine. PLoS One, 9(10):e109490, 2014. doi:10.1371/journal.pone.0109490 Evidence: Very low

      Verified 2026-09-26 · DOI 10.1371/journal.pone.0109490

      • Wiki: Sleep quality
      • What Matters: What actually moves sleep quality
      • Deep dive: What matters most for high-quality sleep