Diet drinks

From the YapSpan Longevity Wiki · Updated 2026-10-01

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Diet drinks, also called artificially sweetened beverages, are soft drinks and other beverages sweetened with low- or no-calorie sweeteners such as aspartame, sucralose or stevia instead of sugar. They provide little or no energy and are often chosen as a replacement for sugary drinks, particularly by people trying to lose weight or manage diabetes.

A 2024 meta-analysis (a study that pools the results of earlier studies) of prospective studies (studies that follow people forward in time) with 2,196,503 participants found that the highest intake of artificially sweetened drinks was associated with 13% higher all-cause mortality (death from any cause) than the lowest [1]. Analyses designed to reduce bias have not found this harm [2].

  • The highest intake of artificially sweetened drinks was associated with 13% higher all-cause mortality and 26% higher cardiovascular mortality than the lowest [1].
  • Replacing one sugary drink a day with an artificially sweetened one was associated with 4 to 6% lower all-cause and cardiovascular mortality [1].
  • Risk followed a J-shaped curve: about 1 serving a day showed no clear excess risk, while 2.5 servings a day was associated with 13% higher all-cause mortality [3].
  • When cohort studies were analysed in ways that reduce bias, low- and no-calorie sweeteners were associated with lower, not higher, all-cause mortality [2].
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YapSpan estimates are for reflection and entertainment only. They are not medical advice, a diagnosis, or a prediction of any individual outcome. Check with a doctor before making any medical decision.